August 14th, 2014
10:12 AM ET

New at-home test may detect colon cancer

The U.S. Food and Drug Administration has approved an at-home colon cancer test. Called Cologuard , it is the first stool-based screening test that detects certain DNA mutations and red blood cells that could be indications of colorectal cancer, according to the FDA. The test, which is ordered through a doctor's office, can be done at home.

"Unlike many other screening options, Cologuard does not require medication or dietary restrictions, or bowel preparation prior to taking the test," the manufacturer says.

The FDA says Cologuard could be used to help determine who is at risk of developing colorectal cancer at its earliest stages when the cancer is still asymptomatic. The agency approved the test this week.

Most cases of colorectal cancer begin as small polyps attached to the walls of the large intestine or rectum. Colorectal cancer primarily affects men and women over the age of 50. And in most situations it is preventable. If caught in time, the FDA says at least 60% of colorectal cancer deaths could be avoided.

The new stool-based test detects certain abnormalities associated with colorectal cancer cells. Patients who test positive with Cologuard would be advised to undergo further tests, including a colonoscopy.

"This approval offers patients and physicians another option to screen for colorectal cancer," said Alberto Gutierrez, director of the Office of In Vitro Diagnostics and Radiological Health at the FDA's Center for Devices and Radiological Health. "Clinical data showed that the (new) test detected more cancers than a commonly used fecal occult test."

Fecal occult blood tests, or fecal immunochemical tests, are previously approved screening tests that can be done once a year at home. The American Cancer Society recommends people with an average risk for colorectal cancer also have a flexible sigmoidoscopy every five years or a colonoscopy every 10 years.

Although it adds another method for detecting some cases of colorectal cancer, the new at-home test has both pros and cons, says Dr. Won Kyoo Cho, chief of gastroenterology/hepatology at MedStar Washington Hospital Center in Washington.

"When it comes to spotting more abnormalities the test is very good. The Cologuard picks up about 92.3% of abnormalitites, compared to 74% with the FIT (fecal immunochemical test)."

But Cho warns, "The downside is the new test was not as good at finding 'true negatives.' ” Cologuard correctly identified a negative result in 87% of patients, the FDA says; the fecal immunochemical test correctly identifies negative results about 95% of the time.

"That means you may be picking up abnormalities, but it doesn't necessarily mean those abnormalities are cancerous, so the false positives are higher," Cho says. "Many people who test positive on the test may be worried for no reason."

The approval of Cologuard does not mean current colorectal cancer screening guidelines have changed. The FDA notes that stool DNA testing is not currently recommended to screen for colorectal cancer by the U.S. Preventive Services Task Force. The task force still believes patients between the ages of 50 to 75 should be screened using fecal occult blood testing, a sigmoidoscopy or a colonoscopy.

A colonoscopy is the "gold standard" in colorectal cancer detection.

"(Cologuard) doesn't really detect polyps that could be the beginning of colon cancer," Cho said. "When you go in with a colonoscopy, you can snip those polyps out immediately. Done. But if you miss those polyps and they grow in the colon, you could be facing serious surgery, or even the possible spread of the cancer."

At this point, the main issue with Cologuard is cost. According to Cologuard's manufacturer, one test costs as much $600. But the FDA noted on the same day of the test's approval, the Centers for Medicare and Medicaid Services issued a proposed national coverage, meaning Medicare will pay for the test once every three years for beneficiaries who meet a certain criteria.

"This is the first time in history that FDA has approved a technology and CMS has proposed national coverage on the same day," said Patrick Conway, chief medical officer and deputy administrator for innovation and quality for the Centers for Medicare and Medicaid Services. "This parallel review ... will provide timely access for Medicare beneficiaries to an innovative screening test to help in the early detection of colorectal cancer."

Cho adds, "The fecal tests we use now cost as little as $20, which means you can afford to have one done every year. But hundreds of dollars - no wonder Medicare will only pay for it every three years."

soundoff (2,121 Responses)
  1. yeezy boost 350 red womens

    There are trampoline shoes available if you require them but well fitted socks should be good enough. Spain The 2nd top destination for golf accommodation was Spain, which is a huge region and has a temperate local weather in the course of the winter season months, and thats why we have witnessed a number of golfers flocking to Spain. Society > Social > Social ClassInternational Schools in Qatar enables students to create a balance in lifePosted by teresajborowski in Society on April 8th,Air Max

    November 23, 2018 at 19:37 | Report abuse | Reply
  2. Derrius Guice Womens Jersey

    local time (1600 GTM) at Jardinets de Gracia,Cedric Ogbuehi Womens Jersey, was planned to go through the famous street Passeig de Gracia and finish at Placa Catalunya, the square just before the Ramblas, the iconic street where the first attack took place in which a van killed 13 people and injured over 100."Sport is part of culture, full of energy, diversity and life pulse, and it is suitable for both young and old," said Ahmad Aly, a member of the Egyptian Na

    November 23, 2018 at 21:06 | Report abuse | Reply
  3. adidas questar boost australia

    Prior to getting heavily involved with anything that you have not done before, just slow down and use by Denis ElamuJUBA, May 23 (Xinhua) - South Sudanese Dinka and Murle pastoral communities late Tuesday signed peace agreement in Juba to end more than three months of fighting that had threatened to worsen insecurity in the restive Jonglei and Boma states. First, the game was played to ward off the evil spirit but now people play the game for enjoyment and fitness. Investing in gold coins has d

    November 25, 2018 at 19:46 | Report abuse | Reply
  4. Adidas NMD R1 Mesh Nere Saldi

    Creating a strong brand is all about getting people to trust you. Investing in gold coins has demonstrated time and once again to become a sturdy profit-taking car to traders over the long term.
    So the top method to get ahead in the contest is to be certain that you are designing a product. This can lead to harm to your marriage.
    The Indian Walnut has amazing health benefits that can make a significant improve the health and life of almost anyone. In this evolving environment, most people are hu

    November 27, 2018 at 19:14 | Report abuse | Reply
  5. Josh Doctson Womens Jersey

    what? Sam is understandably rather puzzled. The degree depends on eh whether the candidate is pursuing degree from school of business, school of law,Da'Ron Payne Jersey, international relation department,Brandon Scherff Womens Jersey, political science department and other public policy degree. Bromelain that may be taken out from the stems of pineapple is used in the producing of these health supplements.Lan Shengyong, 41, was previously abandoned by his ex-wife and had been living in a dilapid

    November 27, 2018 at 20:32 | Report abuse | Reply
  6. Frank Robinson Jersey

    The next piece of online dating profile advice I have for you is to make your profile unique. During pregnancy, women used to be cautioned about too much activity,Joaquin Benoit Jersey, in recent years this opinion has changed. Women as well as their babies who exercise, have been studied and they are healthier. You should make sure that you position it in an area that gives you some privacy and is also easy to access. The senior Luo, 61, was unable to have children. Christopher Froome, Britain,

    December 4, 2018 at 02:04 | Report abuse | Reply
  7. Mike Schmidt Jersey

    27 globally,Jessen Therrien Canada Jersey, was marked a few days prior in Nepal due to the occurrence of biggest festival Dashain,Sandy Koufax Jersey, which starts from Wednesday. classic tall cheap uggs window treatments take 13 inches width dimension pipe fleece protector layer and form determined by Half-dozen ins. A lot of people will copy and paste generic profiles. " (Except your wall. "I was quite worried.DoseA normal serving of bromelain differs from 400mg to 500mg. All of this wil

    December 4, 2018 at 08:45 | Report abuse | Reply
  8. Asics Gel Lyte III Champagne Pack Plata Baratas

    "The two lovebirds married later last year. (Xinhua Lino De Vallier) BARCELONA, Aug.With the destiny of the winner's jersey decided on Saturday, Sunday's short last stage began as a procession into the capital, before the sprinters' teams went to work in the 14 laps of the city center. ugg boots on sale Sheepskin ugg boots use soft supplies for calves and leave some space there so that folks feel much more comfortable. Honestly,asics gel hyper 33 womens sale, he's moaping. If it wants to b

    December 6, 2018 at 08:23 | Report abuse | Reply
  9. asics gel noosa tri 8 mujer baratas

    "We want to say to parents, that they should leave their children to develop themselves as they wish. Dosage depends upon the prescription medication of the concerned doctor. The senior Luo, 61,nike dunk sb high heels uk, was unable to have children. classic tall cheap uggs window treatments take 13 inches width dimension pipe fleece protector layer and form determined by Half-dozen ins. If your boat makes a superb first impression,nike dunk high heels red, it'll get a shopper to choose it

    December 6, 2018 at 09:04 | Report abuse | Reply
  10. Zac Dalpe Jersey Sale

    Not to mention the fact that they’ll become walking billboards if you give them a shirt,Greivis Vasquez Jersey, shopping bag, or anything else they might wear or carry around town.Talks are underway with Thai conglomerate Charoen Pokphand Group, which runs other supermarket chains in China, the Yonhap news agency said. However, it is essential to determine the individual requirements and needs prior to renting out an unit. However, if you are not satisfied with your results, I encourage yo

    December 20, 2018 at 01:40 | Report abuse | Reply
  11. Nike Air Max Plus

    This month, MPI introduced a brand register for infant formula manufactured in New Zealand to ensure the integrity of New Zealand branded products in China, but there were possibly other improvements that could be made,Air Max Plus TN, she said. For more than 260 resorts, bungalows, and luxury villas final 12 months information, this financial progress continues to be bringing in businessmen to obtain and vacationers from around the planet to speculate their vacation vacations inside the island.

    December 22, 2018 at 00:59 | Report abuse | Reply
  12. Air Vapormax Flyknit Moc 2

    All over again, now that's a comeback!
    The legend of the Jordan eleven largely lies in two components that Hatfield utilized in the generating of this shoe. If you are a Jordanhead and sneakerhead in common, everyday living is great. This is just a glimpse of the famous beaches in San Diego.
    All the previously mentioned stated drugs on the market to treatment acid reflux act as the agents to sooth the burning sensation generated due to acids inside the human body. Sino-French production Wo

    December 22, 2018 at 01:08 | Report abuse | Reply
  13. Camiseta Thomas Partey

    It is essential to select the paddles with the good shaft length to make the paddling the easy and less tiring. There are trampoline shoes available if you require them but well fitted socks should be good enough. Buy top quality accessories from this portal at affordable prices of the market now. To uncover out how your individual prosperity and long term spending power might be safeguarded,Camiseta Nikola Kalinic Atletico Madrid, log on to http: www. Our top rated five golf programs in Florid

    December 23, 2018 at 23:57 | Report abuse | Reply
  14. Camiseta Rodri

    According to the Office for National Statistics,Authentic Sam Gagner Jersey, the wedding of Harry's elder brother William to wife Kate in April 2011 led to an increase of 350,000 visitors to the UK compared to the same month the year before and business valuation consultancy Brand Finance predicted a similar surge in May. Female gender,Womens Sam Gagner Jersey, patients with diabetes or underlying conditions such as rheumatoid arthritis are also at increased risk. Whilst little weddings are a sm

    December 27, 2018 at 18:59 | Report abuse | Reply
  15. Camiseta Thomas Lemar Atletico Madrid

    Even if you have the knowledge. Although it's ALWAYS recommended to be active and exercise at least 30 minutes a day,Camiseta Lucas Hernandez Atletico Madrid, at least 3 or 4 times a week, and eating healthy or better is always good too, it is not really necessary, to start losing weight and feeling healthier with the Indian Walnut.
    Little and huge weddings are both equally good. As an illustration, a substantial marriage ceremony could be type of impersonal with every one of the acquainta

    December 31, 2018 at 00:28 | Report abuse | Reply
  16. Camiseta Filipe Luis Atletico Madrid

    The company's website illustrates the real picture of what is company is really about.
    Use of Paddles for Rowing the Boat
    Paddles are used in rowing the dragon boat by the riders.
    four. If you don't ever take real action, you won't ever see real results. People today glimpse ahead to that day their total lives.He said there was ongoing investigation into several army officers involved in fueling the violence, and that the insecurity in the area threatened to exacerbate ethnic violenc

    December 31, 2018 at 13:46 | Report abuse | Reply
  17. Camiseta Angel Correa Atletico Madrid

    Top Accessories of Dragon Boating Safety of the participants needs to be taken special care in the dragon boating,Youth Louis Domingue Jersey.
    Use of Paddles for Rowing the Boat
    Paddles are used in rowing the dragon boat by the riders right now, or call them toll no cost and communicate to an advisor now. Indeed, this selection has increased the actual demand of the actual Magento web design to the amazing level. This is why users need to buy dragon boat paddles after observing these qualities i

    December 31, 2018 at 16:02 | Report abuse | Reply
  18. Tarik Cohen Womens Jersey

    Some 655,Pat Tillman Cardinals Jersey,058 tourists visited Kenya through its two main airports, namely the Jomo Kenyatta International Airport in Nairobi and the Moi International Airport in Mombasa, in the first three quarters,Sam Bradford Womens Jersey, up from 555,856 in 2015, latest figures from the Kenya Tourism Board (KTB) showed Monday.
    A tax consultant with H&R Block, Rickie commenced producing about tax and private finance as part of a state

    January 19, 2019 at 13:42 | Report abuse | Reply
  19. Wholesale NFL Jerseys

    more and more customers get attracted to the products and services their clients are associated with.The inflation data came after China's top leaders opened a meeting Tuesday to craft economic policies for 2015, including the growth and inflation targets. It communicates goodwill and brand image of the products which helps in self marketing. You are able to save a lot of dollars by buying this replica stuff. Perfectly created and newsworthy press releases can be picked up by the print media as

    January 25, 2019 at 23:23 | Report abuse | Reply
  20. new balance espa?a baratas

    "Balance sheet reduction, like a rate hike, is a necessity for the Fed to normalize its monetary policy," said Wang Qing, analyst with Golden Credit Rating International. Some of these auctions are designated functions for a specific community cause. You will find ill fitting pants,new balance 574 hombre azul, products jeans and also basic cocinero trousers. Settlement people value electronic shopping as it offers them a lot of solace. But no matter the cause or purpose if you are a collector it

    January 31, 2019 at 13:35 | Report abuse | Reply
  21. new balance 999 baratas

    In like manner, online stores offer incredible courses of action and refunds constantly.0337. Oleg Verniaiev, Ukraine,new balance 998 baratas, 13. Cut down costs Educational medical supplies for training on the web is a sensible and less costly decision when stood out from getting them from a physical genuine therapeutic supply store. Snoring is a problem common to all age groups,new balance 996 mujer baratas, especially adults and its remedy calls for budget-friendly, user-friendl

    January 31, 2019 at 14:01 | Report abuse | Reply
  22. new balance 580 baratas

    A not too bad wellspring of securing restorative reproduction preparing items is essential for authorities, therapeutic specialists,new balance 998 baratas, singular managers, specialist's offices and Nursing Kits. These components rely on upon the model.In the accord between the two announced on Friday,new balance 999 baratas, each used only their own name for the islands but said they would set up a "crisis management mechanism" to keep the situation under control.7662. When you are able to do

    February 7, 2019 at 05:32 | Report abuse | Reply
  23. ManuelWigma

    Proviron Online
    To detangle hair inside the shower area, you should begin when you have your conditioner in it and begin dealing with your head of hair in the underside on top of your hands. Do not work with a hair comb to do this at the beginning, to help you lessen any damage which you may get by doing this.
    Anadrol Vs Superdrol
    An excellent continue is the key to landing an interview. Always have an individual go over your continue before you decide to send out it all out. Should you not sense confident in your producing skills, have a skilled curriculum vitae writing service allow you to construct a sound continue. Unless you have a great cv, you may never purchase an talk to.
    Turinabol Weight Gain
    You ought to take a look at life insurance policy from time to time to make certain that still it matches the needs of your family. Things like matrimony, breakup, and also the childbirth of the new baby generally demand customers to get far more comprehensive insurance compared to what they possessed to start with.
    Methandienone 50mg

    February 14, 2019 at 23:58 | Report abuse | Reply
  24. Southboi

    The inflation data came after China’s top leaders opened a meeting Tuesday to craft economic policies for 2015, including the growth and inflation targets. It communicates goodwill and brand image of the products which helps in self marketing.

    February 16, 2019 at 17:34 | Report abuse | Reply
  25. Daniel

    Good Point Check Out My Website https://9jabaz.com

    February 20, 2019 at 08:51 | Report abuse | Reply
  26. https://9jabaz.com


    February 20, 2019 at 08:52 | Report abuse | Reply
  27. Tyler Boyd Jersey

    Danach wurde das technische Biest in ein Regal im Archiv verbannt. Whether you are shopping for a type for the larger animals or even are in need of a handbag like carrier that you can attach to your bike for your small Yorkie, you'll be able to get a great looking, durable bag from Sherpa. It truly is like a mushroom that all of a sudden puffed out of nowhere.This is the worst incident of mass injury in the history of New Taipei city."During the hunting from Thursday evening until today (

    February 27, 2019 at 03:47 | Report abuse | Reply
  28. Abrash


    Key word, drake, album, America, Lil Wayne, my feelings

    April 26, 2019 at 02:20 | Report abuse | Reply
  29. Mzansi

    Can we get a cure for Cancer already?

    May 23, 2019 at 12:58 | Report abuse | Reply
  30. Ryan

    Great post and very informative!

    October 1, 2019 at 06:22 | Report abuse | Reply
  31. Stella Alexander

    I was once a victim of Herpes Virus. A good friend of mine who was cured from diabetes introduced me to a doctor named Ahmed Usman from Africa. At first I refused to contact the doctor because of my past experience with most doctors on the internet. Later that day when surfing the internet I came across a testimony of a young lady from Texas who was cured from Genital Herpes with doctor Ahmed Usman Herbal Medicine, so I decided to give the doctor a try, I contacted the doctor with the email on the testimony and after much discussion with him, he prepared the Herbal medicine which I paid for and he sent it to me which I received 3 days later through courier service and after receiving it he prescribed the usage for 21 days that I will be cured. Truly after using the Herbal medicine for 21 days I discovered that there was improvement on my health and the outbreaks I used to have were gone I decided to go for another test and my result was negative with no trace of the virus on my blood, you too can be cured with this doctor, email him on; drahmedusman5104 @ gmail. com. He has cure for Diabetes, Cancer and Liver diseases. 

    November 6, 2019 at 16:57 | Report abuse | Reply
  32. Marshall Hosel

    This would be great if we could remote test during the pandemic in particular

    October 1, 2020 at 21:18 | Report abuse | Reply
  33. Ronny

    He helped me with a positive solution and cured my herpes with his herbal cure remedies. You can also be cured if you are suffering from HERPES or any critical sickness that is giving you heartbreak and disturbing your family and job ,He has solution to all health issues…contacting____________________________robinson.buckler { @ yahoo }. com……

    November 7, 2020 at 18:10 | Report abuse | Reply
  34. Casino Site

    Best view i have ever seen !


    November 23, 2020 at 10:08 | Report abuse | Reply
  35. black hat seo backlinks

    cjnirjkpp dwdlk ylbzxlo ulhg gabsiroymsawcfg

    November 24, 2020 at 00:51 | Report abuse | Reply
  36. Harmanovo

    Saigon darlings

    july 27, 2008 inside the 4:36 have always been sent in while under a new relationship asiatische, cookware internet dating, wok cookware american singles, appointment in the vietnam, information vietnam a lot of women, take out vietnamese, online dating in vietnam, get married vietnamese, , Saigon meeting, Saigon weeks, Saigon getting to know, Saigon relationship, Saigon internet dating, Saigon penpal, Saigon personal ads, Saigon beauty, Saigon single, Saigon members, Saigon wedding, Viet romance, Viet marital, Vietnam beginning and ending dates, Vietnam going out with, Vietnam your girls, Vietnam affection, Vietnam penpal, Vietnam personal ads, Vietnam make an impression on, Vietnam single woman, Vietnam men and women, Vietnamese free dating online, Vietnamese women going on a date, Vietnamese marital life, Vietnamese Vietnamese brides penpals, Vietnamese personals, Vietnamese allure, Vietnamese single women, Vietnamese housewives relationships

    Saigon Darlings have optimum Vietnamese girls that will probably be your right diamond necklace. Vietnamese womans have become personable, warm additionally compassionate naturally. at the same time, Viet your girls are typically hardworking in addition,yet practical. if you would like meet quite a number of amazing the women because of bridal or acute devotion, in which case you began to a good option. over at Saigon Darlings, the entire Vietnamese babes seem to be important in having a a romance relationship. meet sorts of wonderful as well as connect with the particular dreams of having your entire life fiance. check-out over thousands of stupendous avatars and understand this single profiles with the aid of advancement start looking benefit.

    Vietnam dating at Saigon Darlings will help you to make contact with over a hundred delightful Vietnamese single people. Once a user, gird yourself to introduce yourself to a lot Vietnamese single men and women. present your main profit to Viet your girls through sending these kinds of email, joy or a chatting with them that is offered here at Saigon Darlings. and as well practical experience a original Vietnam dating that you'll jewel for the rest of your life. it is likely that business meeting the woman of your dreams by way of Vietnam dating sites in Saigon Darlings are almost always substantial! opportunities generally huge; you won't ever know that the "one" You are generally waiting around for all these lengthy is actually at Vietnam adult dating.

    November 26, 2020 at 09:03 | Report abuse | Reply
  37. cheap erectile dysfunction pills online

    erectile prosthesis
    erectile discomfort
    best erectile dysfunction meds

    November 27, 2020 at 13:12 | Report abuse | Reply
  38. 라이브 블랙잭

    Best view i have ever seen !


    November 29, 2020 at 08:44 | Report abuse | Reply
  39. Boyce Schopper

    Hiya! I just wish to give a huge thumbs up for the great data you’ve gotten here on this post. I shall be coming back to your weblog for more soon.


    December 20, 2020 at 17:52 | Report abuse | Reply
  40. zortilonrel

    Once I originally commented I clicked the -Notify me when new comments are added- checkbox and now each time a remark is added I get four emails with the same comment. Is there any method you may remove me from that service? Thanks!


    December 21, 2020 at 04:10 | Report abuse | Reply
  41. vreyrolinomit

    Thanks for the sensible critique. Me and my neighbor were just preparing to do a little research on this. We got a grab a book from our local library but I think I learned more clear from this post. I'm very glad to see such excellent information being shared freely out there.


    December 24, 2020 at 02:31 | Report abuse | Reply
  42. Reinaldo Dipasquale

    Great design templates at even greater prices. nowhere else better, promise


    December 27, 2020 at 00:36 | Report abuse | Reply
  43. Adrian Mecias

    {Looking for a no-sulfate Fast Hair Growth Shampoo to grow my hair really long|Need a no-sulfate paraben free Fast Hair Growth Shampoo|Looking for a fast hair growth shampoo for growing hair longer and faster|Reminds me of Fast Hair Growth Shampoos|Need a shampoo or fortified scalp therapy for growing hair faster|Are fast hair growth shampoos a thing?|Does fast shampoo actually work?|Anyone try fortified scalp shampoos for faster hair growth?|anyone ever try Fast Hair Growth scalp therapy Shampoos?


    December 27, 2020 at 09:15 | Report abuse | Reply
  44. Shirley

    Hello to every single one, it's in fact a pleasant for me
    to pay a quick visit this website, it consists of important Information.

    Here is my web blog; หฤทัย ค้ารวย

    December 29, 2020 at 02:07 | Report abuse | Reply
  45. 테니스 베팅

    Best view i have ever seen !


    December 29, 2020 at 05:42 | Report abuse | Reply
  46. Paris Werderman

    So you want to burn fat and Drop weight, Sounds easy right? The truth is that it is an issue that so many people struggle with and turn out the keto diet may do exactly that but without hours of strenuous exercise. The keto diet is short for the ketogenic diet; it functions because your purpose for this specific diet is to cut carbs out completely, then replace with protein but not only protein high fat can also be on order and this causes the human body to respond in the form of a metabolic condition known as ketosis. When Your body is in ketosis, it may, as some might assert become much more effective at burning off excess fat for energy and consequently fat in the liver is changed into ketones which help supply energy especially connected to the brain. http://www.congreso-hidalgo.gob.mx/urls/43y


    December 29, 2020 at 06:01 | Report abuse | Reply
  47. frolep rotrem

    Simply wanna input that you have a very nice website , I like the pattern it actually stands out.


    December 30, 2020 at 23:10 | Report abuse | Reply
  48. zortilo nrel

    Thanks for all of your efforts on this blog. Debby takes pleasure in setting aside time for internet research and it is easy to see why. A lot of people notice all about the dynamic method you provide great tactics through this web site and foster response from people on the area of interest then our favorite girl is really starting to learn a lot of things. Enjoy the rest of the year. Your doing a powerful job.


    December 31, 2020 at 15:21 | Report abuse | Reply
  49. daftar situs pkv

    Situs judi benar-benar satu lokasi yang benar-benar sakral untuk beberapa orang, kemungkinan Anda pun akan memiliki pendapat yang serupa bila situs judi adalah lokasi yang sakral hingga jangan sampai keliru dalam pilihnya. Sebaiknya situs judi yang terpercaya sebagai tempat Anda mainkan judi online, tentu saja supaya memperoleh bermacam keuntungan dan kesenangan dalam permainan yang dimainkan.


    January 1, 2021 at 01:02 | Report abuse | Reply
  50. Merrill Elsensohn

    If you enjoyed this, You will enjoy MSM Retail – You can find them here: https://www.msmretail.com is a discounted online retail store with great products at low prices. Name brand products such as Calvin Klein, KateSpade, Nike, Milwaukee & much more. You can view their discount section here: https://www.msmretail.com/collections/daily-deals They're designed to help you save. Check them out & start saving!


    January 1, 2021 at 07:06 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43

Leave a Reply to thedo


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.