home
RSS
Study: Don't delay measles vaccine
May 19th, 2014
02:18 PM ET

Study: Don't delay measles vaccine

There are many myths about vaccinations floating around the Internet, says Dr. Simon Hambidge. One - that giving vaccinations too close together is unhealthy - has prompted some parents to request that their children receive vaccines on an alternate schedule, Hambidge told CNN in an e-mail.

Hambidge, an expert in pediatric vaccination with Kaiser Permanente's Institute for Health Research Colorado, is lead author of a new study that examines the association between vaccine timing and seizures.

His team found that in the first year of life, there is no relationship between the recommended vaccine schedule and seizures. But delaying the measles vaccine until after a child is 15 months old may raise his or her seizure risk. The study results were published Monday in the journal Pediatrics.

"A number of people have claimed that a young child’s immune system is not robust enough to be given multiple vaccines, and that it is safer to 'spread out' vaccination," Hambidge said. "There is no scientific evidence for this, and there is evidence that it is safe and effective to follow the current recommended schedule."

Background

Parents who don't comply with recommended guidelines for childhood vaccines are in a sizable minority.

A study using the 2009 National Immunization Survey found that 25.8% of parents delayed the vaccines, 8.2% refused to get their children vaccinated, and 5.8% both delayed and refused, Hambidge said. The rest did not delay or refuse. These data come from parents of children aged 24 to 35 months.

Parents' fears are mostly about autism, Hambidge said, even though no scientific link has been proven between the two.

Methods

For this study, researchers obtained data on more than 300,000 children born between 2004 and 2008. They looked at a variety of different vaccines and their associated seizure risks.

There are two options for vaccinating children against measles: the measles-mumps-rubella (MMR) vaccine plus a separate varicella vaccine, and the measles-mumps-rubella-varicella (MMRV) vaccine. The Centers for Disease Control and Prevention tells parents that while MMRV results in one fewer vaccine, it is associated with a higher risk of seizures.

U.S. health authorities recommend that children receive their first dose of the MMR or MMRV vaccine at 12 to 15 months of age.

Results

The study suggests that children who receive childhood vaccines in the first year of life do not have an associated risk of seizure. But seizure risk may increase in the second year of life with measles vaccines specifically.

The overall risk of seizures in vaccines that contain measles is "real but very low," Hambidge said - it's about 1 in 4,000 doses, according to previous research. It appears that the risk of seizures is about 2 in every 4,000 doses for children who receive the first MMR vaccine between 16 and 23 months of age.

"Febrile seizures that occur after MMR vaccine are rare and temporary – these children are not at increased risk of epilepsy," Hambidge said. "The risk of catching measles disease is far more serious, especially as we are seeing increased cases of measles in the U.S."

(A febrile seizure is a convulsion in young children that may be caused by a spike in body temperature, often from an infection.)

Meanwhile, the study found that getting the MMRV vaccine, instead of the MMR and varicella vaccines separately, increases the risk of seizures twofold - regardless of whether the vaccine was given on time. The association with seizures was strongest for children who received the MMRV vaccine between 16 and 18 months of age.

The results support a 2010 study that found additional febrile seizure risk from using MMRV instead of MMR plus varicella separately. But the absolute risk remains small: For every 2,300 MMRV doses given in the second year of life, there is one additional febrile seizure in the seven to 10 days following vaccination.

Recommendations

"This study supports the currently recommended vaccination schedule from the CDC as the best choice for protecting children from serious disease and minimizing adverse events from vaccination," Hambidge said.

Bottom line: Do what your doctor says and vaccinate against measles on time. Have a conversation about MMRV versus MMR if you have questions or concerns. The CDC recommends receiving the MMR and varicella injections separately.

"Because the U.S. is seeing the largest increase in measles cases in recent memory due to unvaccinated travelers returning from trips abroad, the risk of not vaccinating a child for measles or for delaying vaccination is that the child is left vulnerable to catching measles, which is a very serious disease," Hambidge said.

Related: Measles cases at highest level in nearly 20 years


soundoff (364 Responses)
  1. MileSwa

    buy cialis overnight shipping cialis from india generic cialis pills

    June 1, 2021 at 10:28 | Report abuse | Reply
  2. EncoxAni

    online pharmacy ed canadian pharmacy cheap reviews pharmacy rx one coupon codes

    June 1, 2021 at 18:16 | Report abuse | Reply
  3. Zisseloh

    cialis troche viagra and cialis combination cialis with viagra

    June 2, 2021 at 04:52 | Report abuse | Reply
  4. EJblsudMGvHeaUQ

    XtmLsJalyS

    June 2, 2021 at 10:56 | Report abuse | Reply
  5. EncoxHtf

    cialis for enlarged prostate \'generic cialis\' cialis in india

    June 3, 2021 at 09:53 | Report abuse | Reply
  6. Zisseloh

    dr oz cialis local generic cialis in united states pictures of penis on cialis

    June 3, 2021 at 15:43 | Report abuse | Reply
  7. tadalafil sublingual

    tadalafil drug evolution peptides tadalafil tadalafil side effects

    June 3, 2021 at 17:05 | Report abuse | Reply
  8. EncoxDev

    stat rx pharmacy rx clinic pharmacy pharmacy salaries in canada

    June 3, 2021 at 19:35 | Report abuse | Reply
  9. EncoxGtv

    canadian pharmacy generic viagra g and e pharmacy edmonton store hours desoxyn online pharmacy

    June 3, 2021 at 20:00 | Report abuse | Reply
  10. tadalafil sublingual

    tadalafil dosage purchase peptides tadalafil tadalafil online with out prescription

    June 3, 2021 at 23:20 | Report abuse | Reply
  11. Al Delpit

    This was great! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusufhanafy

    June 4, 2021 at 02:18 | Report abuse | Reply
  12. ZisseVed

    generic cialis uk online generic cialis at walmart cialis soft online

    June 4, 2021 at 10:17 | Report abuse | Reply
  13. hydroxychloroquine plaquenil cost

    chloroquine side effects buy hydroxychloroquine online chroloquine

    June 4, 2021 at 10:36 | Report abuse | Reply
  14. CrulkAsd

    where to buy cialis online for cheap discount cialis online farmacy cialis

    June 4, 2021 at 11:22 | Report abuse | Reply
  15. gALysQuv

    ljoPrtGbxvyM

    June 4, 2021 at 15:43 | Report abuse | Reply
  16. cialis pills

    c-tadalafil buy cialis online cialis tadalafil

    June 4, 2021 at 19:36 | Report abuse | Reply
  17. Tonette Uranga

    This was awesome! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusufhanafy

    June 4, 2021 at 21:11 | Report abuse | Reply
  18. hydrodiuril

    chloroquine hydroxychloroquine sulfate australia chloroquinone

    June 6, 2021 at 20:25 | Report abuse | Reply
  19. dolquine

    hydroxychloroquine tablet clonidine hcl hydroclorizine

    June 7, 2021 at 05:44 | Report abuse | Reply
  20. EncoxAni

    Keflex prescription drugs prices comparison non prescription online pharmacy reviews

    June 7, 2021 at 07:27 | Report abuse | Reply
  21. MileSwa

    cheap cialis by post generic cialis usps priority mail cialis, money order

    June 7, 2021 at 07:34 | Report abuse | Reply
  22. Audry Tix

    This was awesome! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusufhanafy

    June 7, 2021 at 08:40 | Report abuse | Reply
  23. EncoxGtv

    walmart pharmacy viagra canada pharmacy checker reviews of canadian pharmacy

    June 7, 2021 at 09:53 | Report abuse | Reply
  24. CrulkAsd

    best price cialis 20mg cialis online overnight shipping cialis online/canada

    June 7, 2021 at 15:48 | Report abuse | Reply
  25. ZisseVed

    how long does it take for cialis 20mg to work cialis troche lilly cialis coupon

    June 7, 2021 at 21:17 | Report abuse | Reply
  26. EncoxHtf

    cialis capsule cialis benefits cialis generic available

    June 8, 2021 at 02:11 | Report abuse | Reply
  27. aralen price usa

    what is in hydroxychloroquine hidroxicloroquina antimalarial drug hydroxychloroquine

    June 8, 2021 at 03:59 | Report abuse | Reply
  28. EncoxDev

    can you use target pharmacy rewards online cvs pharmacy store manager salary buy phentermine online canadian pharmacy

    June 8, 2021 at 06:30 | Report abuse | Reply
  29. EncoxAni

    heb online pharmacy northwest drugs canada modafinil online pharmacy

    June 8, 2021 at 15:47 | Report abuse | Reply
  30. MileSwa

    cialis without prescription howard stern commercial cialis buy generic cialis

    June 9, 2021 at 03:44 | Report abuse | Reply
  31. Zisseloh

    comprar cialis viagra levitra cialis comparison tadafil cialis

    June 9, 2021 at 07:27 | Report abuse | Reply
  32. Zisseloh

    when is generic cialis coming out cialis past expiration date cialis sizes

    June 9, 2021 at 15:39 | Report abuse | Reply
  33. EncoxHtf

    buying cialis from mexico 5mg of cialis generic cialis

    June 10, 2021 at 00:12 | Report abuse | Reply
  34. Derrick Scoville

    This was great! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusufhanafy

    June 10, 2021 at 03:27 | Report abuse | Reply
  35. EncoxGtv

    big mountain drugs canada my rx pharmacy true rx pharmacy

    June 12, 2021 at 07:02 | Report abuse | Reply
  36. EncoxDev

    rx plus pharmacy nyc quick rx pharmacy canadian no prescription pharmacy

    June 12, 2021 at 10:10 | Report abuse | Reply
  37. Heidy Wuellenweber

    Have you ever heard of second life (sl for short). It is essentially a video game where you can do anything you want. SL is literally my second life (pun intended lol). If you would like to see more you can see these sl articles and blogs

    http://beyondnewhorizons.com/2009/05/a-fresh-look/

    June 12, 2021 at 14:56 | Report abuse | Reply
  38. Emanuel Dakes

    I don't know about you people but I infatuated with airplanes. I have a friend in highschool that loves airplanes, so here are some airplane related stuff I don't know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2010/01/house-cleaning-interesting-stories-i-didnt-get-around-to-blog-about/

    http://urlm.co/g/c/f/163870

    June 13, 2021 at 01:26 | Report abuse | Reply
  39. ZisseVed

    us cialis online pharmacy daily cialis price comparison of 10 mg cialis price

    June 13, 2021 at 02:10 | Report abuse | Reply
  40. Kayla Nordsiek

    I don't know about you guys but I love airplanes. I have a friend in highschool that loved airplanes, so here are some airplane related stuff I don't know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2010/10/travel-time-off-to-tokyo/

    http://everydayliteracies.blogspot.com/2018/05/border-crossers.html?showComment=1536852677216

    June 13, 2021 at 16:09 | Report abuse | Reply
  41. CrulkAsd

    cialis viagra sales cialis w/o perscription safest and most reliable pharmacy to buy cialis

    June 13, 2021 at 17:31 | Report abuse | Reply
  42. Willetta Dilucca

    Have you ever heard of second life (sl for short). It is essentially a video game where you can do anything you want. SL is literally my second life (pun intended lol). If you want to see more you can see these sl articles and blogs

    http://adolit.blogspot.com/2007/05/its-baaack.html

    June 14, 2021 at 19:20 | Report abuse | Reply
  43. roIRgpPXwvQUKW

    lJQbArnfCIVxmS

    June 15, 2021 at 15:03 | Report abuse | Reply
  44. cad 3d

    750539 423593I believe this internet site contains some quite great information for everyone : D. 931604

    June 19, 2021 at 02:52 | Report abuse | Reply
  45. Michal Feaster

    Have you ever heard of second life (sl for short). It is essentially a game where you can do anything you want. sl is literally my second life (pun intended lol). If you would like to see more you can see these second life authors and blogs

    http://myvedana.blogspot.com/2005/02/watch-your-back.html?m=0

    June 21, 2021 at 16:04 | Report abuse | Reply
  46. pharmacepticacom

    sildenafil 20 https://pharmaceptica.com/

    June 23, 2021 at 17:14 | Report abuse | Reply
1 2 3 4 5 6 7

Leave a Reply to FmrfEncox


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.