Do men have a biological clock of sorts? A large new study suggests they may.

Compared to younger fathers, older fathers' children were found to be significantly more at risk for a host of psychiatric disorders, according to the study, published Wednesday in the journal JAMA Psychiatry.

For example, the children of fathers ages 45 and over were three times more likely to have an autism spectrum disorder, 13 times more likely to have ADHD, and 25 times more likely to have bipolar disorder than the children of fathers aged 20 to 24.

For the study, researchers analyzed data from 2.6 million children born in Sweden between 1973 and 2001, making it one of the largest and most comprehensive studies on the effects of paternal age.

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