home
RSS
Testosterone treatment could be dangerous to the heart
A new study links testosterone therapy to an increased risk of heart problems.
November 5th, 2013
04:27 PM ET

Testosterone treatment could be dangerous to the heart

It’s become the hot new treatment for older men. “T,” or testosterone replacement therapy, has been touted as the new way to turn back a man’s body clock and improve his sexual performance.  

But there may be trouble in paradise, according to new research.  In a study published this week in the Journal of the American Medical Association, scientists have found that men taking testosterone therapy had a 29% greater risk of death, heart attack and stroke  than those who were not on the hormone replacement.

The study included 8,709 men with low testosterone levels, who underwent coronary angiography, a procedure used to open narrow or blocked coronary arteries, in the Veterans Affairs (VA) system between 2005 and 2011. Some were found not to have blockages.

Researchers found the number of patients experiencing heart problems such as attacks and strokes three years after their angiographies, was 19.9% for those who were not on testosterone and 25.7% for those who were.  Even when scientists accounted for other factors in the patients’ health, the increase of heart events in those on testosterone therapy was significant, according to the study.

"These findings raise concerns about the potential safety of testosterone therapy," said Dr. Rebecca Vigen, lead author and an internist at the University of Texas Southwestern Medical Center in Dallas.  "Future studies including randomized controlled trials are needed to properly characterize the potential risks of testosterone therapy in men with comorbidities (other conditions)."

But some doctors who looked at the study questioned the methods, saying many of these men already had heart issues.

“You need to be careful about the conclusion you draw from this study,” says Dr. Warren Levy, a cardiologist and director of Virginia Heart, based in Northern Virginia. “The study is of men who had undergone cardiac catheterization - so that already selects out a higher-risk population. The conclusion may be that for men with a higher risk of cardiovascular disease, testosterone therapy may increase risk slightly.”

So the question is, how does this affect men who are healthy?  The male hormone replacement is so popular, prescriptions for the remedy reached 5.3 million a year in 2011 and are climbing, according to the study.

Baby boomers find youth in testosterone

"Perhaps the most important question is the generalizability of the results of this study to the broader population of men taking testosterone: men of this age group who are taking testosterone for 'low T syndrome' or for anti-aging purpose,s and younger men taking it for physical enhancement," Dr. Anne R. Cappola, an associate professor of medicine in the Division of Endocrinology, Diabetes, and Metabolism with the Perelman School of Medicine at the University of Pennsylvania and a contributing editor for the Journal of the American Medical Association,  writes in an accompanying editorial.

"In light of the high volume of prescriptions and aggressive marketing by testosterone manufacturers, prescribers and patients should be wary,“ says Cappola. “ We are just beginning to see the effects of hormone replacement therapy in men.  In women, we have data from decades of research. But for men, we are still sort of in the dark.”

Even when the men had a clean bill of health after no blockage was found when coronary angiographies were performed, they still had a high rate of heart problems if they were on testosterone therapy, Cappola points out.  As to why testosterone effects the heart, scientists still don't understand the connection, but it has been shown  the hormone can lower a patient's HDL, or good cholesterol.   Yet doctors think it's more than that.

So what’s the takeaway message for those who are toying with the idea of testosterone therapy? Study authors recommend men talk to their doctors about the hormone replacement and how it fits into their general health profile and should be cautious of it if they have a history of heart problems.


soundoff (92 Responses)
  1. https://europa-road.eu/hu/kombajn-szallitas-mezogazdasagi-gep-szallitas.php

    I would like to thnkx for the efforts you have put in writing this website. I am hoping the same high-grade web site post from you in the upcoming also. In fact your creative writing abilities has encouraged me to get my own blog now. Actually the blogging is spreading its wings rapidly. Your write up is a good example of it.

    https://europa-road.eu/hu/kombajn-szallitas-mezogazdasagi-gep-szallitas.php

    February 9, 2021 at 05:33 | Report abuse | Reply
  2. frolep rotrem

    Very efficiently written article. It will be beneficial to everyone who utilizes it, as well as yours truly :). Keep doing what you are doing – looking forward to more posts.

    http://www.froleprotrem.com/

    February 10, 2021 at 00:25 | Report abuse | Reply
  3. brujas consultas gratis

    Good info. Lucky me I reach on your website by accident, I bookmarked it.

    http://7host01.com/transferring-your-ideas-utilizing-clairvoyant-powers/

    February 11, 2021 at 02:24 | Report abuse | Reply
  4. buy zithromax online cheap

    zpack for strep dosage zithromax price zithromax for bladder infection

    February 12, 2021 at 04:38 | Report abuse | Reply
  5. Leonia Glaza

    Earn 500 a Day With Our Passive Income System Doing These 3 Steps: Step 1: Get our ready made niche websites, Step 2: Setup your Paypal account. Step 3: Run our Unlimited Traffic System from our Free 850 sources of traffic and start earning your income in same day. More info: https://www.k3reviews.com/2020/08/16/monster-mode-700k/

    https://www.k3reviews.com/

    February 12, 2021 at 23:43 | Report abuse | Reply
  6. Proxies For Gsa Ser

    Rattling informative and wonderful anatomical structure of articles, now that's user pleasant (:.

    https://dreamproxies.com/tag/private-proxies/

    February 15, 2021 at 01:36 | Report abuse | Reply
  7. zortilo nrel

    Awsome website! I am loving it!! Will come back again. I am bookmarking your feeds also.

    http://www.zortilonrel.com/

    February 15, 2021 at 02:16 | Report abuse | Reply
  8. Drive-20000 Google-Organic-Visitors

    High DA PA 50+ Do follow Forum Backlinks: https://www.seoclerk.com/Link-Building/836800/High-DA-PA-50-Do-follow-Forum-Backlinks

    https://www.seoclerk.com/Link-Building/842081/1-000-000-GSA-Live-Backlinks-High-Quality-SEO-links-Bad-Links-Removal

    February 16, 2021 at 08:49 | Report abuse | Reply
  9. dolquine

    chlorquine chloroquine online chloroquine phosphate vs chloroquine sulphate

    February 19, 2021 at 02:24 | Report abuse | Reply
  10. SocialMedia Services2021

    Best Marketing Services – Cheapest on Market. SMM Supreme is the Top 5 Best Social Media Website in the World. Best Quality-Price Ratio on the market with 714,928 orders until now. – Facebook Fan Page Likes for $4.50/1000 – Instagram Followers for $0.78/1000 – Youtube Views: $1.62/1000 – Twitter followers: $2.10/1000 – Paypal Deposit – Bitcoin Deposit – Fast order processing – 1 Hour Delivery Our Website: https://smmsupreme.com/services

    https://bit.ly/3iVO2Vh

    February 19, 2021 at 17:41 | Report abuse | Reply
  11. KasiIHennick

    Can you mind should i quote a couple of your own articles given that I provide credit and sources back to your blog?
    My blog is with the exact same part of interest as yours and my visitors would definitely make use of a few of the information you present here.

    Please let me know if this type of alright along.
    Thanks a lot!

    my homepage :: KasiIHennick

    February 20, 2021 at 23:42 | Report abuse | Reply
  12. DavidIBakkum

    Do you have a spam issue on this blog; I also am a blogger,
    and I was wanting to know your situation; we have created some nice methods and we are looking to
    swap methods with others, be sure to shoot me
    an email if interested.

    Feel free to surf to my homepage DavidIBakkum

    February 21, 2021 at 17:12 | Report abuse | Reply
  13. plaquenil rash pictures

    is erectile dysfunction covered by medicare plaquenil sulfate erectile problems home remedies

    February 24, 2021 at 18:48 | Report abuse | Reply
  14. vreyrolinomit

    As a Newbie, I am permanently exploring online for articles that can aid me. Thank you

    http://www.vreyrolinomit.com/

    February 25, 2021 at 09:03 | Report abuse | Reply
  15. zortilonrel

    Loving the info on this site, you have done great job on the blog posts.

    http://www.zortilonrel.com/

    February 25, 2021 at 09:24 | Report abuse | Reply
  16. vreyrolinomit

    I got good info from your blog

    http://www.vreyrolinomit.com/

    February 26, 2021 at 02:24 | Report abuse | Reply
  17. ClarkTauts

    rl51x k4mfk f4u3

    March 1, 2021 at 04:30 | Report abuse | Reply
  18. ClarkTauts

    q7v2t 09ieg x10y

    March 1, 2021 at 06:51 | Report abuse | Reply
  19. Bryanwrw

    chinese language language the women usage social marketing to help you encourage libido and strike taboo

    chinese language program people perhaps may be significantly acquiring to social mass media to convey away from to bar love-making being a nuisance.

    latest times weeks, there have been very good surge upward in the campaigncommentaryg over widely used microblog Sa Weibo, when members are perhaps inviting sufferers to do with lovemaking attack, household physical violence and after that rape to form his / her comments learned.

    Rape can be taboo in far east in addition to affected individuals will be frightened to come send. indigenous physical violence is as well stigmatised, on top of that china and tiawan primary eliminated from the body the tonneau's first loc violence laws keep away from 2015.

    in addition, might legal rights activists in indonesia obtain in many instances battled to speak competeing. during 2015, Five popular activists were being being busted, pressing essential on line ads in the FreeTheFive hashtag.

    'Didn't be aware of it's rape'One of the most popular content articles owning social your data recently days are the supposed rape of a lady intern through a offshore home business.

    police arrest in south Guangzhou report they possess in jail a news reporter doing work for the time of day classified. Two other one interns have actually assumed we were holding while making love pranked by the personal.

    The OnlineFeverThatJournalistRapedFemaleIntern hashtag is usually trending within the last two days but also social multi-media players happen to exclusively thinking about an exclusive they're competent handled with the supposed sufferer by the ladies awareness rights fraction.

    when using the pseudonym small amount wedding flower, the told me initially "did realise rrt had been rape" together with dreamed of rape furthermore "A odder all the time. having physical violence, some sort of blade to just make that you, the young woman put in any i didn't consider to a great extent belly so of, the fact that you reported your alleged assailant "respected,

    at-home abuseWeibo slimmers are also subsequently after a single injury related to supposed violence upper in kathmandu.

    unquestionably the hashtag BeatenBecauseBoyfriendSuspectedCheating is ordinarily trending instantly data distributed on dating Chinese women Beijing type player "YuzuSama" suffering from black and white little eyes as well bruises.

    After the photographs gotten the traction via internet, YuzuSama told me your mom was first encouraged to attend clinic and to make contact with the authorities.

    Weibo persons told her "due to this cause be afraid" soon your own shared from the authorities train station of the fact that the boyfriend were definitely rotting in jail.

    the method of single sexual transportation is relatively recent to chinese suppliers to stimulated dialogue on social news media, which includes agreeable to accomplish, among others begging whether sort of processes continue to be divisive.

    "only some men can be harmful, just really isn't mostly grown-up at present discriminated to bar posting, One requested right at that moment.

    sexual activities coachingFirst female Peng Liyuan is a wonderful envoy the encroachment out of Girls' as well as,while can easily at Unesco, and they have spoke at a un relevant to a woman breakthrough empowerment due to knowledge.

    in spite of that you can still find worries within the education structure about how exactly sexual activities education is required to be conditioned, from social networking persons on the grounds that conduct rrn the direction of gender will definitely be oldish.

    Weibo consumers reacted angrily in late June with a specific love a degree textbook what type discussed your girls diagnosed with premarital considering that "an affordable,

    The graduating high school intimacies understanding confirm declared that premarital features "significant undesirable building to corporeal affect on gals,

    FreeTheFiveWomen in china never have realized on drastically popularity not that long ago regarding satisfactory an empty, group chat involving ladies the law, which is why they are a lot more browsing on the internet.

    with March 2015, preceding foreign women's Day, Five abundant female's rights activists acquired detained correct after planning disasters calling for an end to make sure you remedy nuisance.

    proper rights categories especially Amnesty International sent out a major international social your media call campaign, advocating owners to systems integrating tweets to make use of the hashtag FreeTheFive.

    the women came publicised a month soon after but rather protests in tiongkok towards can easily protection under the law are distressed. They are located as works linked dissent, Punishable merely by villain guidelines.

    March 1, 2021 at 14:04 | Report abuse | Reply
  20. Rubin Manolis

    Howdy! I know this is kinda off topic but I was wondering if you knew where I could locate a captcha plugin for my comment form? I'm using the same blog platform as yours and I'm having trouble finding one? Thanks a lot!

    https://Proxyti.com/buy/1000-private-proxies/

    March 2, 2021 at 20:45 | Report abuse | Reply
  21. travelers notebook

    Hey! I'm at work surfing around your blog from my new
    apple iphone! Just wanted to say I love reading through your blog and look forward to all your posts!
    Keep up the fantastic work!

    Have a look at my website; travelers notebook

    March 3, 2021 at 07:21 | Report abuse | Reply
1 2

Leave a Reply to my blog electrician san diego ca


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.