home
RSS
Copper may be a trigger of Alzheimer's disease
August 19th, 2013
03:54 PM ET

Copper may be a trigger of Alzheimer's disease

Copper, which is found in anything from drinking water to red meats, may be an environmental trigger of Alzheimer’s disease, according to a new study.

The study, published Monday in the journal Proceedings of the National Academy of Sciences, suggests copper keeps toxic proteins from leaving the brain.

It is clear that, over time, copper impairs the systems through which amyloid beta is removed from the brain, said Rashid Deane, a research professor in the University of Rochester Medical Center  Department of Neurosurgery, member of the Center for Translational Neuromedicine, and lead author of the study.  This causes the protein "to accumulate in the brain and form the plaques that are the hallmark of Alzheimer's disease."

Copper is usually found in drinking water that is carried by copper pipes.  It is also found in shellfish, meats, nuts and many vegetables and fruits.   The mineral is important for the body because it helps with the development of the nervous system, along with bone growth and hormone secretion.

Researchers looked at the effect of copper-laced drinking water on mice. They used low doses of copper over a three-month period. The dose was 10% of the maximum contaminant level set by the Environment Protection Agency.

"These are very low levels of copper, equivalent to what people would consume in a normal diet." said Deane. "We chose copper in water because it is easily absorbed in the blood."

Even with the low levels of copper, scientists found a buildup of toxic proteins in the brain. The toxic protein is called amyloid beta, which is a component of amyloid plaques that have been previously connected to Alzheimer's disease.

Research conducted using mice doesn't necessarily translate to humans, but study authors found that in both mice and human brain cells, copper exposure prohibited the removal of the harmful protein from the brain. Researchers also found that copper exposure led to a breakdown of the blood- brain barrier, making it easier for copper to get into the brain as well.

"Copper is an essential metal, and it is clear that these effects are due to exposure over a long period of time," said Deane. "The key will be striking the right balance between too little and too much copper consumption. Right now we cannot say what the right level will be, but diet may ultimately play an important role in regulating this process."

Deane says people should know more about copper and its effects.  "Because of what I do, I believe in preventive medicine and practices," notes Deane.  "Copper is essential.  But maybe, just maybe, if we are finding that copper is creating a problem in the brain, we should back off on supplements, look at labels on foods and know how much copper we are putting in our bodies.  We don't need to overdo it."


« Previous entry
soundoff (129 Responses)
  1. Best Window Washing Service Near Me Globeville

    best i have ever seen!Hello, always i used to check webpage posts here early in the daylight, for the reason that i love to gain knowledge of more and more.

    https://ebusinesspages.com/Signature-Window-Washing_eb5ap.co

    April 10, 2021 at 07:26 | Report abuse | Reply
  2. Best Window Washing Service Near Me Jefferson Park, Denver, CO

    Really very happy to say,your post is very interesting to read.I never stop myself to say something about it.You're doing a great job.Keep it up

    https://www.igotbiz.com/directory/listingdisplay.aspx?lid=59570

    April 10, 2021 at 08:21 | Report abuse | Reply
  3. Best Window Washing Service Near Me Lower Highlands, Denver, CO

    This is a very interesting article. Please, share more like this!

    http://www.lacartes.com/business/Signature-Window-Washing/1794313

    April 10, 2021 at 08:54 | Report abuse | Reply
  4. Window Washing Service Platt Park, Denver, CO

    nice information for a new blogger. it is really helpful

    http://www.myhuckleberry.com/business-listing.aspx?id=26055965

    April 10, 2021 at 10:05 | Report abuse | Reply
  5. Best Window Washing Service Near Me Golden Triangle, Denver, CO

    this is very informative and intersting for those who are interested in blogging field.

    http://www.myhuckleberry.com/business-listing.aspx?id=26055965

    April 11, 2021 at 05:12 | Report abuse | Reply
  6. Window Cleaning Service South Park Hill, Denver, CO

    this is very informative and intersting for those who are interested in blogging field.

    https://www.superpages.com/denver-co/bpp/signature-window-washing-550947371

    April 11, 2021 at 05:40 | Report abuse | Reply
  7. Window Cleaning Service Lower Highlands, Denver, CO

    Impressive! Thanks for the post

    http://www.salespider.com/b-487999294/signature-window-washing

    April 11, 2021 at 06:11 | Report abuse | Reply
  8. Best Window Washing Service Near Me East Colfax, Denver, CO

    Impressive! Thanks for the post

    https://www.yelp.com/biz/signature-window-washing-denver-4?osq=Signature+Window+Washing

    April 11, 2021 at 07:36 | Report abuse | Reply
  9. Window Washing Service Lower Highlands, Denver, CO

    Impressive! Thanks for the post

    https://medium.com/@tiptopkhanjohn/benefits-of-hiring-a-professional-window-cleaner-2cb9db461a97

    April 11, 2021 at 08:51 | Report abuse | Reply
  10. AC Repair Apopka

    carry on, dont stop

    https://goo.gl/maps/usG3VzyikjDQGWhu5

    April 14, 2021 at 14:21 | Report abuse | Reply
  11. signature window cleaning denver

    Thanks for wonderful information I used to be in search of this info for my mission.

    http://windowcleaningdenver.blogprodesign.com/22709563/is-it-necessary-to-hire-a-commercial-window-cleaning-services

    April 15, 2021 at 11:14 | Report abuse | Reply
1 2 3

Leave a Reply to Profitable-Digital-Marketing Strategy-and-Plan


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

« Previous entry
Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.