home
RSS
Antiviral drugs help prevent HIV infection in IV drug users
June 12th, 2013
06:01 PM ET

Antiviral drugs help prevent HIV infection in IV drug users

Treating intravenous drug users with antiviral drugs may reduce their chances of HIV infection, according to a new study published Wednesday in the British medical journal The Lancet.

The Bangkok Tenofovir Study was done in Bangkok, Thailand, from 2005-2013. It was run by the Centers for Disease Control and Prevention in collaboration with the Thailand Ministry of Public Health.

Researchers recruited more than 24,000 people at 17 sites. Half took the pill tenofovir - an antiretroviral drug - daily, while the other half got a placebo. Participants were followed for about four years. Researchers found those taking the drug cut their chances of infection by 49% almost in half - approximately 49%.

This is not the first study to prove that PrEP - pre-exposure prophylaxis - is effective in reducing HIV transmission in high risk groups. Studies have already been done in heterosexuals as well as gay and bisexual men. But according to the CDC, this is the first study of its kind to prove effective in reducing rates among those who inject drugs.

“This study completes the picture of PrEP efficacy for all major HIV risk groups," said Dr. Michael Martin, chief of clinical research for the Thailand Ministry of Public Health-CDC collaboration. "We now know that pre-exposure prophylaxis can be a potentially vital option for HIV prevention in people at very high risk for infection, whether through sexual transmission or injecting drug use.”

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said, "The real important advance here is the proof of concept that in yet another high risk group - IV-drug users - pre-exposure prophylaxis can work if the individuals adhere to taking the drug."

The study found that the reduction rate for those who took their daily dose routinely was even higher - 74%.

“Adherence was a key factor determining efficacy in our trial among people who inject drugs,  as it has been in previous PrEP trials examining sexual transmission,” said Martin. “These results underscore the importance of helping people using pre-exposure prophylaxis achieve effective levels of adherence.”

It can often be difficult to directly attribute the antiviral drug's protective effect on people who get infected by injecting drugs, said Salim Karim, professor and director of the Centre for the AIDS Programme of Research in South Africa (CAPRISA) at the University of KwaZulu-Natal in Durban, South Africa. That's because, he says, some IV drug users engage in risky behavior such as prostitution to support their drug habit.

“Even though questions remain about the extent to which PrEP can be effective in preventing either of the routes of transmission in this group, the overall result is that daily tenofovir does reduce HIV transmission in injecting drug users," Karim said. "The introduction of PrEP for HIV prevention in injecting drug users should be considered as an additional component to accompany other proven prevention strategies like needle exchange programmes, methadone programmes, promotion of safer sex and injecting practices, condoms, and HIV counseling and testing.”

UNAIDS, the Joint United Nations Programme on HIV/AIDS, called the study results a complement to other PrEP trials released over the past few years.

“Piece by piece, scientific advances are paving the way to the end of the AIDS epidemic,” said Michel Sidibé, UNAIDS executive director. “The full potential of antiretroviral therapy in keeping people alive and well and in preventing new HIV infections is becoming apparent. The results of this study are important, and if used effectively in HIV programming, could have a significant impact in protecting people who inject drugs from becoming infected with HIV.”

So far, all evidence suggests PrEP is safe and effective for reducing the risk of HIV infection in high-risk populations, and there have been no concerns regarding its use daily, the CDC says.


soundoff (939 Responses)
  1. remodeled rvs interior

    Good article! We will be linking to this particularly great content on our website. Keep up the good writing.

    https://www.preissuchmaschine.de/link.asp?url=https://www.ocrvmotorsports.org

    June 5, 2021 at 10:43 | Report abuse | Reply
  2. Sprinter Door Rust Repair

    I wanted to thank you for this excellent read!! I absolutely loved every little bit of it. I've got you saved as a favorite to look at new stuff you postÖ

    http://dairy4life.com/__media__/js/netsoltrademark.php?d=sprinterrepairnearme.com

    June 6, 2021 at 02:52 | Report abuse | Reply
  3. Sprinter Heater Valve Repair

    The very next time I read a blog, I hope that it won't disappoint me just as much as this particular one. After all, Yes, it was my choice to read through, but I genuinely believed you would probably have something interesting to say. All I hear is a bunch of crying about something you could possibly fix if you weren't too busy seeking attention.

    http://radio.cancaonova.com/iframe-loader/?t=Dating Single: No Longer a Mystery – Rádio&ra=&url=http://ocrv.me/rv-repair-shop-fontana-california

    June 6, 2021 at 03:57 | Report abuse | Reply
  4. covid test near me

    Great site you've got here.. Itís difficult to find quality writing like yours these days. I really appreciate individuals like you! Take care!!

    http://acelszerkezet.com/phpinfo.php?a%5B%5D=https://nearmyspot.com/

    June 6, 2021 at 08:43 | Report abuse | Reply
  5. Sprinter Van Repair Laguna Niguel

    I blog frequently and I genuinely thank you for your content. This great article has truly peaked my interest. I am going to book mark your site and keep checking for new information about once a week. I subscribed to your Feed too.

    https://rock-club.net/out.php?url=http://fleetservicesocrv.com/

    June 6, 2021 at 15:29 | Report abuse | Reply
  6. EncoxDev

    pharmacy jobs canada pharmacy tech practice tests online www canadian pharmacies

    June 7, 2021 at 05:53 | Report abuse | Reply
  7. Barney Magwood

    This was awesome! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusufhanafy

    June 7, 2021 at 06:03 | Report abuse | Reply
  8. EncoxGtv

    canadian online pharmacy importing drugs from canada cheapest pharmacy canada

    June 7, 2021 at 08:56 | Report abuse | Reply
  9. motorhome interior remodel

    Great web site you have got here.. Itís hard to find good quality writing like yours nowadays. I seriously appreciate individuals like you! Take care!!

    http://handlerkron.com/__media__/js/netsoltrademark.php?d=www.ocrv.club

    June 7, 2021 at 11:02 | Report abuse | Reply
  10. Repair Sprinter Seat

    http://sherlock.scribblelive.com/r?u=ocrv.rocks/rv-repair-shop-encinitas-california

    June 7, 2021 at 13:49 | Report abuse | Reply
  11. CrulkAsd

    generic canadian cialis paypal cialis payment cialis greece

    June 7, 2021 at 14:46 | Report abuse | Reply
  12. Zisseloh

    cialis otc usa where to get cialis cheap ebay cialis

    June 7, 2021 at 21:08 | Report abuse | Reply
  13. ZisseVed

    when to take cialis 20mg does cialis help prostate free cialis coupon 2018

    June 7, 2021 at 21:43 | Report abuse | Reply
  14. RV Service And Repair Near Me

    Great site you have here.. Itís difficult to find quality writing like yours these days. I honestly appreciate people like you! Take care!!

    https://www.etypeservices.com/Flash/LinkRedirection.aspx?IssueID=46912&Returnurl=https://ocrv.fun/rv-repair-shop-lynwood-california

    June 8, 2021 at 00:41 | Report abuse | Reply
  15. semi truck shop near me

    https://trends.gab.com/visit?url=https://ocrv.world/rv-lighting-repair-near-me

    June 8, 2021 at 01:28 | Report abuse | Reply
  16. rv restoration companies

    I must thank you for the efforts you have put in writing this site. I really hope to check out the same high-grade content by you later on as well. In fact, your creative writing abilities has inspired me to get my own, personal website now 😉

    https://cloudsso.hikvision.com/logout?service=http://ingenieurleistungenreiter.de/index.php?option=com_phocaguestbook&view=phocaguestbook&id=1&Itemid=4&t=160&limitstart=81940

    June 8, 2021 at 01:49 | Report abuse | Reply
  17. RV Shower Near Me

    https://www.prodesigns.com/redirect?url=http://hootnholler.net/category/uncategorized/page/149/

    June 8, 2021 at 01:54 | Report abuse | Reply
  18. EncoxHtf

    do you need a prescription for cialis cialis 5mg vs 20mg best prices for cialis 20mg

    June 8, 2021 at 12:20 | Report abuse | Reply
  19. MileSwa

    cialis in usa cialis lion cheap cialis alternatives

    June 8, 2021 at 20:56 | Report abuse | Reply
  20. rv slide out repair parts

    https://go.20script.ir/index.php?url=https://ocrv.art/rv-ac-repair-near-me

    June 8, 2021 at 21:53 | Report abuse | Reply
  21. RV Entertainment System Riverside

    https://www.treasury.gov/cgi-bin/redirect.cgi/?https://abusinessblender.worldblogged.com/3038192/the-best-side-of-rv-repair-shop

    June 8, 2021 at 23:37 | Report abuse | Reply
  22. Best Tucker Sprinter Repair

    That is a good tip particularly to those new to the blogosphere. Short but very accurate informationÖ Thank you for sharing this one. A must read post!

    &cp_1=washington&cp_2=myteams-nbc-sports&cp_3=nbcsphi1356

    June 8, 2021 at 23:45 | Report abuse | Reply
  23. trailer body repair near me

    https://za.zalo.me/v3/verifyv2/pc?token=OcNsmjfpL0XY2F3BtHzNRs4A-hhQ5q5sPXtbk3O&continue=ocrvfleetservices.com

    June 9, 2021 at 01:26 | Report abuse | Reply
  24. Video Marketing Firms

    Greetings! Very helpful advice in this particular post! It's the little changes which will make the biggest changes. Many thanks for sharing!

    http://feed.thepund.it/?url=https://internetmarketingnevada.com/

    June 9, 2021 at 09:17 | Report abuse | Reply
  25. Daniell Solan

    This was awesome! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusufhanafy

    June 9, 2021 at 10:04 | Report abuse | Reply
  26. Awilda Drewett

    You should be a part of a contest for one of the highest quality sites on the web. I'm going to highly recommend this web site!

    https://brooksm04e6.blogaritma.com/4054429/5-simple-techniques-for-sprinter-van-repair

    June 9, 2021 at 13:22 | Report abuse | Reply
  27. Long Skaer

    A motivating discussion is definitely worth comment. I think that you need to write more on this subject matter, it may not be a taboo subject but usually folks don't talk about such issues. To the next! Best wishes!!

    https://bitly.com/a/warning?hash=3nUs1YL&url=https://emilianoq92s0.get-blogging.com/6049836/the-best-side-of-eye-doctor

    June 9, 2021 at 14:42 | Report abuse | Reply
  28. Yolanda Hollmann

    Itís difficult to find educated people in this particular topic, however, you sound like you know what youíre talking about! Thanks

    https://www.fhwa.dot.gov/reauthorization/reauexit.cfm?link=https://griffing69k8.myparisblog.com/4713363/how-much-you-need-to-expect-you-ll-pay-for-a-good-sprinter-repair

    June 9, 2021 at 14:42 | Report abuse | Reply
  29. ZisseVed

    cutting cialis in half cialis viagra combination generic cialis quick shipping

    June 9, 2021 at 18:48 | Report abuse | Reply
  30. EncoxAni

    ventolin canada pharmacy canadian pharmacy near me Female Cialis Soft

    June 9, 2021 at 18:59 | Report abuse | Reply
  31. Social Media Marketing Companies

    http://dotnet40.logicmelon.com/SimpleProxy.ashx?url=http://www.juicycalls.com/

    June 9, 2021 at 19:05 | Report abuse | Reply
  32. Roseline Dallago

    Can I simply say what a relief to uncover someone who truly understands what they're talking about on the internet. You definitely realize how to bring an issue to light and make it important. More people ought to check this out and understand this side of your story. It's surprising you aren't more popular given that you most certainly possess the gift.

    https://cristianh60p9.blogsumer.com/4068751/a-secret-weapon-for-maserati-repair-shops-near-me

    June 9, 2021 at 20:48 | Report abuse | Reply
  33. Elijah Barb

    Way cool! Some very valid points! I appreciate you writing this write-up and the rest of the site is really good.

    http://help.dedecms.com/plus/player/index.php?url=https://manuel2sx24.blog4youth.com/4393978/top-latest-five-commercial-truck-repair-near-me-urban-news

    June 10, 2021 at 01:25 | Report abuse | Reply
  34. Neva Lefeld

    https://ditu.google.cn/url?q=http://hectorq92t0.dgbloggers.com/4916621/digital-marketing-agency-things-to-know-before-you-buy

    June 10, 2021 at 01:43 | Report abuse | Reply
  35. rv repair shop

    https://stevemorse.org/hebrew/ytrans2.php?url=http://jasper4f7z5.blogsvila.com/3496659/top-rv-repair-near-me-secrets

    June 10, 2021 at 02:48 | Report abuse | Reply
  36. Lezlie Southern

    I could not refrain from commenting. Well written!

    https://connert63m2.blogcudinti.com/4161018/a-secret-weapon-for-personal-injury-attorney

    June 10, 2021 at 04:16 | Report abuse | Reply
  37. EncoxHtf

    best seller cialis cialis flushing cialis blood pressure

    June 10, 2021 at 06:58 | Report abuse | Reply
  38. Sonny Heddlesten

    This blog was... how do I say it? Relevant!! Finally I've found something which helped me. Appreciate it!

    https://franciscog69l7.blogdomago.com/4386449/significance-of-appointed-day-effective-date-in-restructuring

    June 10, 2021 at 11:39 | Report abuse | Reply
  39. Destiny Parlor

    http://www.bshare.cn/share?url=https://andersonq03v1.bloggazza.com/4353505/what-s-daily-life-coaching-and-why-everyday-living-coaching-may-be-to-suit-your-needs

    June 10, 2021 at 12:06 | Report abuse | Reply
  40. rv repair near me

    This site definitely has all the information I needed concerning this subject and didnít know who to ask.

    https://it.paltalk.com/client/webapp/client/External.wmt?url=https://54.249.99.185/blog/timlelliott/20140531105950.html

    June 10, 2021 at 12:09 | Report abuse | Reply
  41. Darline Barbarito

    I used to be able to find good information from your blog posts.

    https://www.treasury.gov/cgi-bin/redirect.cgi/?https://www.paxtonl30f9.theideasblog.com/4663099/repair-shop-for-dummies

    June 10, 2021 at 12:38 | Report abuse | Reply
  42. Loren Korman

    Iím amazed, I have to admit. Seldom do I encounter a blog thatís both equally educative and amusing, and let me tell you, you have hit the nail on the head. The issue is something that not enough men and women are speaking intelligently about. I am very happy that I stumbled across this during my search for something regarding this.

    https://ditu.google.cn/url?q=http://jasperl80p9.is-blog.com/5990070/time-for-kitchen-transforming-five-signs-that-provide-you-with-it-is-time-to-remodel

    June 10, 2021 at 12:38 | Report abuse | Reply
  43. clonidin

    hydroxycloroquine buy aralen online uk hydroxychloroquine sulphate

    June 10, 2021 at 18:43 | Report abuse | Reply
  44. Frederica Radulescu

    https://kamerono04c4.activosblog.com/4096784/repair-shop-fundamentals-explained

    June 10, 2021 at 19:03 | Report abuse | Reply
  45. rv repair service near me

    Having read this I believed it was very informative. I appreciate you taking the time and energy to put this article together. I once again find myself personally spending way too much time both reading and commenting. But so what, it was still worth it!

    https://www.paltalk.com/client/webapp/client/External.wmt?url=https://gregory8c5g6.techionblog.com/3491367/an-unbiased-view-of-rv-repairs-near-me

    June 10, 2021 at 21:30 | Report abuse | Reply
  46. Cristopher Isaacsen

    I like it whenever people get together and share views. Great blog, keep it up!

    June 10, 2021 at 22:43 | Report abuse | Reply
  47. Silas Renter

    I really love your website.. Excellent colors & theme. Did you develop this site yourself? Please reply back as Iím attempting to create my own personal website and would like to know where you got this from or what the theme is named. Thank you!

    June 10, 2021 at 23:32 | Report abuse | Reply
  48. Amira Seager

    I have to thank you for the efforts you've put in penning this website. I am hoping to see the same high-grade blog posts from you later on as well. In truth, your creative writing abilities has motivated me to get my own, personal website now 😉

    http://www.bshare.cn/share?url=https://franciscof58j6.jiliblog.com/59333308/relevance-of-appointed-day-efficient-date-in-restructuring

    June 10, 2021 at 23:32 | Report abuse | Reply
  49. Alva Walter

    https://manueln30d8.laowaiblog.com/4047399/about-van-repair-shop

    June 11, 2021 at 02:26 | Report abuse | Reply
  50. rv repair

    https://georgewbushlibrary.smu.edu/exit.aspx?url=https://checkipdomain.com/search/rv-storage-near-me

    June 11, 2021 at 06:50 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.