Colon cancer spotted by blood test
June 7th, 2013
01:30 PM ET

Colon cancer spotted by blood test

For the field of cancer research, a reliable blood test for colorectal cancer would be a revelation. Currently, the condition is diagnosed through stool blood tests and uncomfortable colonoscopies, but the dream is to be able to find genetic markers predictive of such cancers in order to intervene early or follow patients in their treatment.

A study published Friday in the Journal of Molecular Diagnostics suggests that a blood test for colon cancer could be on the horizon. But the research is still preliminary and the test is not currently recommended as a screening tool, said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society.

The lifetime risk of developing colorectal cancer is 1 in 20, and men are slightly more likely to get it than women, according to the American Cancer Society. In 2013, it is expected to cause more than 50,000 deaths.

The study

Researchers at Genomictree, Inc., and the Yonsei University College of Medicine in Seoul, South Korea, first went on a "search mission" to find genes that could be related to colorectal cancer tissue, Lichtenfeld said. They compared tumor tissue samples from patients to non-tumor tissue, and identified candidate genes that could be markers for colon cancer. They focused on one for further investigation, a marker called SDC2.

Then, scientists took blood samples from 12 colon cancer patients with various stages of cancer, to look for that gene. They found that this gene was present, and could be detected, in the patients' blood. In these patients, the gene was predictive for colon cancer.

Bigger picture

The ultimate goal of this line of research is to find a blood test that would either find cancer early or help doctors follow patients in their treatment to see how it's working, Lichtenfeld said.

This research shows that this particular gene may be a marker that could be useful in either following colon cancer patients, or potentially defining colon cancer early and saving lives, he said.

Ultimately, however, doctors want to be able to identify a lesion before it becomes cancerous, Lichtenfeld said. The authors of this study not claim that this blood test will do that.

It's unknown whether this particular test would find colon cancer early enough to save lives or prevent people from developing the disease, Lichtenfeld said. More research needs to be done.

Other candidates

This isn't the only potential marker for colon cancer that a blood test could pick up. There are other genes that other research groups are looking at, too.

Study authors wrote that their findings are similar to those of the SEPT9 test for colorectal cancer. SEPT9 is a gene that has also been correlated with the condition. A 2011 study in the journal BMC Medicine showed the potential for that gene to serve as a marker in a blood test for colorectal cancer - but this research is not definitive either.

"No reputable organization is recommending that either of these tests be used as screening test for colon cancer," Lichtenfeld said.

The SEPT9 test is being marketed with claims that it could replace a colonoscopy, but the American Cancer Society does not recommend it at this time, Lichtenfeld said.

soundoff (799 Responses)
  1. Ford Cargo Van Repair Shop Near Me


    May 31, 2021 at 23:16 | Report abuse | Reply
  2. Custom Paint Shop


    May 31, 2021 at 23:41 | Report abuse | Reply
  3. Sid Matsui

    This was awesome! I would like you to clean up all this spam though


    June 1, 2021 at 00:01 | Report abuse | Reply
  4. 08 Sprinter Intake PRT Repair

    Your style is unique compared to other people I have read stuff from. Many thanks for posting when you have the opportunity, Guess I'll just book mark this blog.


    June 1, 2021 at 01:50 | Report abuse | Reply
  5. RV Window Repair Near Me


    June 1, 2021 at 02:50 | Report abuse | Reply
  6. Van Repair Shop

    I used to be able to find good info from your articles.


    June 1, 2021 at 04:29 | Report abuse | Reply
  7. RV Body Repair Shops Near Me


    June 1, 2021 at 08:14 | Report abuse | Reply
  8. Rv Paint Shop

    I must thank you for the efforts you've put in penning this site. I'm hoping to check out the same high-grade content by you later on as well. In truth, your creative writing abilities has inspired me to get my very own blog now 😉


    June 1, 2021 at 11:45 | Report abuse | Reply
  9. does rv insurance cover roof leaks

    I blog often and I genuinely thank you for your information. The article has really peaked my interest. I'm going to take a note of your site and keep checking for new information about once per week. I opted in for your Feed as well.


    June 1, 2021 at 12:36 | Report abuse | Reply
  10. box truck repair panels

    This site definitely has all the information and facts I needed about this subject and didn’t know who to ask.


    June 1, 2021 at 15:06 | Report abuse | Reply
  11. Maile Philpotts

    Your style is so unique in comparison to other people I have read stuff from. Thank you for posting when you've got the opportunity, Guess I will just bookmark this site.


    June 1, 2021 at 15:26 | Report abuse | Reply
  12. rv slide repair

    Great info. Lucky me I came across your website by accident (stumbleupon). I've book-marked it for later!


    June 1, 2021 at 15:27 | Report abuse | Reply
  13. My Carwin

    Oh my goodness! Awesome article dude! Thanks, However I am having troubles with your RSS. I don’t know why I am unable to subscribe to it. Is there anybody getting the same RSS problems? Anyone who knows the answer can you kindly respond? Thanx!!


    June 1, 2021 at 16:03 | Report abuse | Reply
  14. Restoration Shop Near Me

    That is a great tip particularly to those new to the blogosphere. Simple but very accurate information… Many thanks for sharing this one. A must read article!


    June 1, 2021 at 16:34 | Report abuse | Reply
  15. Cristal Martire


    June 1, 2021 at 22:16 | Report abuse | Reply
  16. i repair near me


    June 2, 2021 at 00:49 | Report abuse | Reply
  17. rv plumbing leak

    Greetings, I do believe your site might be having internet browser compatibility issues. When I take a look at your web site in Safari, it looks fine however, when opening in Internet Explorer, it has some overlapping issues. I just wanted to provide you with a quick heads up! Other than that, excellent blog!


    June 2, 2021 at 01:12 | Report abuse | Reply
  18. Taobao delivery agency

    Hi, i think that i saw you visited my blog so i got here to go back the
    desire?.I am attempting to in finding things to enhance
    my web site!I assume its ok to use a few of your ideas!!

    June 2, 2021 at 03:51 | Report abuse | Reply
  19. paint shops near me


    June 2, 2021 at 05:36 | Report abuse | Reply
  20. Matilde Bronsky

    You are so cool! I do not believe I've read something like that before. So nice to discover another person with some original thoughts on this issue. Seriously.. many thanks for starting this up. This web site is one thing that's needed on the web, someone with a little originality!


    June 2, 2021 at 08:48 | Report abuse | Reply
  21. Danilo Glatter


    June 2, 2021 at 10:42 | Report abuse | Reply
  22. Chevrolet Luxury Van Repair Shop Near Me


    June 2, 2021 at 13:06 | Report abuse | Reply
  23. Yung Mui


    June 2, 2021 at 14:02 | Report abuse | Reply
  24. all rv repair

    Good post. I will be going through some of these issues as well..


    June 2, 2021 at 15:01 | Report abuse | Reply
  25. ankara escort

    What i don't realize is in truth how you're not actually a lot more well-appreciated than you might be
    now. You are very intelligent. You recognize therefore considerably on the subject of this subject, made me personally imagine it from a lot of
    varied angles. Its like women and men don't seem to be involved unless it's one thing to
    accomplish with Woman gaga! Your individual stuffs excellent.

    All the time maintain it up!

    June 2, 2021 at 15:47 | Report abuse | Reply
  26. Rebbeca Marcon

    Have you ever heard of second life (sl for short). It is basically a online game where you can do anything you want. SL is literally my second life (pun intended lol). If you would like to see more you can see these Second Life articles and blogs


    June 2, 2021 at 22:43 | Report abuse | Reply
  27. Local Marketing Services


    June 3, 2021 at 00:46 | Report abuse | Reply
  28. Sprinter Van Windshield Replacement Shop Near Me

    I was able to find good info from your blog articles.


    June 3, 2021 at 01:50 | Report abuse | Reply
  29. oc windshield

    Excellent web site you've got here.. It’s hard to find high quality writing like yours nowadays. I seriously appreciate people like you! Take care!!


    June 3, 2021 at 04:34 | Report abuse | Reply
  30. Social Media Marketing Specialist Near Me

    It’s hard to find experienced people about this subject, however, you seem like you know what you’re talking about! Thanks


    June 3, 2021 at 05:28 | Report abuse | Reply
  31. Authorized Sprinter Repair Facility


    June 3, 2021 at 07:26 | Report abuse | Reply
  32. Dodge Sprinter Repair Shops

    Good post. I learn something totally new and challenging on websites I stumbleupon everyday. It will always be helpful to read content from other authors and practice something from other web sites.


    June 3, 2021 at 07:43 | Report abuse | Reply
  33. RV Windows Riverside


    June 3, 2021 at 08:53 | Report abuse | Reply
  34. Video Marketing Business


    June 3, 2021 at 10:28 | Report abuse | Reply
  35. Sprinter Repair Costa Mesa


    June 3, 2021 at 11:05 | Report abuse | Reply
  36. Sprinter Seat Fabric Repair

    This is a topic which is near to my heart... Thank you! Where are your contact details though?


    June 3, 2021 at 16:28 | Report abuse | Reply
  37. orange skye body and beauty bar

    Pretty! This was an extremely wonderful article. Many thanks for supplying this information.


    June 3, 2021 at 16:33 | Report abuse | Reply
  38. tv repair orange county ca

    Oh my goodness! Awesome article dude! Thank you so much, However I am having troubles with your RSS. I donít know why I can't join it. Is there anyone else getting similar RSS problems? Anyone that knows the solution will you kindly respond? Thanks!!


    June 3, 2021 at 16:39 | Report abuse | Reply
  39. camera shop california

    I need to to thank you for this good read!! I certainly loved every bit of it. I've got you book-marked to look at new things you postÖ


    June 3, 2021 at 16:40 | Report abuse | Reply
  40. RV Repair And Service Near Me


    June 3, 2021 at 16:41 | Report abuse | Reply
  41. Internet Marketing Companies Near Me

    Nice post. I learn something totally new and challenging on blogs I stumbleupon on a daily basis. It will always be exciting to read articles from other authors and use a little something from their web sites.


    June 3, 2021 at 22:23 | Report abuse | Reply
  42. geico store near me


    June 4, 2021 at 00:13 | Report abuse | Reply
  43. car sound system repair near me

    Everything is very open with a precise description of the issues. It was really informative. Your website is very helpful. Thanks for sharing!


    June 4, 2021 at 01:50 | Report abuse | Reply
  44. Digital Marketing Businesses

    Everything is very open with a precise clarification of the issues. It was definitely informative. Your site is useful. Many thanks for sharing!


    June 4, 2021 at 01:55 | Report abuse | Reply
  45. trailer repair near me

    I love reading through a post that can make men and women think. Also, thanks for permitting me to comment!


    June 4, 2021 at 01:59 | Report abuse | Reply
  46. Mercedes Sprinter Van Abs Repair


    June 4, 2021 at 02:00 | Report abuse | Reply
  47. arcade near me

    I could not refrain from commenting. Well written!


    June 4, 2021 at 02:00 | Report abuse | Reply
  48. Sprinter Heater Contol Repair

    Your style is so unique in comparison to other people I've read stuff from. Thanks for posting when you have the opportunity, Guess I'll just book mark this site.


    June 4, 2021 at 04:14 | Report abuse | Reply
  49. Bernita Prost

    This was awesome! I would like you to clean up all this spam though


    June 4, 2021 at 09:12 | Report abuse | Reply
  50. RV Engine Repair Near Me


    June 4, 2021 at 09:38 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16

Leave a Reply to Social Media Marketing Contractors


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.