home
RSS
Cold sores linked to cognitive decline
March 26th, 2013
10:04 AM ET

Cold sores linked to cognitive decline

The virus causing your cold sore may put you at risk for something more insidious: Lower cognitive abilities.

In a study of 1,625 people, researchers at Columbia University measured specific antibodies to common infectious agents in each person's blood, and using this information, created an "infectious burden index." Participants higher on the infectious burden index were more likely to have worse cognition, or cognitive abilities.

The study, published Monday in the journal Neurology, further suggests a link between cognitive decline and herpesviridae viral infections in particular, which previous studies have also linked to Alzheimer's disease and risk of stroke, an accompanying editorial notes. Herpesviridae is a family of viruses including HSV-1 or herpes simplex virus-1, which causes cold sores and can cause genital herpes, and HSV-2, which commonly causes genital herpes.

For the study, researchers tracked participants for eight years, giving them tests to measure cognition each year, but found no link between decline in abilities and viral infections over that period. The associated decline occurred before the study even began; the participants infectious burden index score did not make that person more or less likely to experience cognitive decline over the course of the study.

Only physical activity significantly reduced the association between infectious burden and cognitive decline, researchers found.

A study starting with younger participants - this study's average was 69 years old - and over a longer period may reveal more about how the decline progresses over time, says Dr. Mira Katan, the lead study author.

"While this association needs to be further studied, the results could lead to ways to identify people at risk of cognitive impairment and eventually lower that risk," said Katan in a statement.

"For example, exercise and childhood vaccinations against viruses could decrease the risk for memory problems later in life."

"This is a fascinating area which certainly deserves a treatment trial," says Dr. Timo Strandberg, author of the editorial, from the Department of Medicine, geriatric clinic, at the University of Helsinki (Finland) and University Hospital in Helsinki. "We are currently planning one... just remember what a paradigm change there was in ulcer disease in the 1980s. Of course this could have great potential if proved to be right. Nevertheless, old age AD (Alzheimer's disease) is a multifactorial geriatric syndrome (in my opinion), so several factors are contributing at the individual level."

However, said Dr. William Schaffner, chairman of the preventive medicine department at Vanderbilt University's School of Medicine, "They cannot impute causal associations, these are just interesting phenomenon."

"My concerns are, who are these people who are drawn into these studies? Because they're not a representative population," says Schaffner, who was not involved in the research. "They of course have had a dropout rate, so I'm just very cautious about what we can conclude from this association."

But Schaffner says he finds the study "intriguing and provocative"  He says, "The more we pick at this and find infectious disease antecedents for chronic illness, the more provocative it is, because it opens up more doors for prevention."


soundoff (335 Responses)
  1. LbsoZisse

    cialis online canada ripoff http://ucialisdas.com/ cialis black to buy in the uk

    May 15, 2021 at 17:33 | Report abuse | Reply
  2. RebfZisse

    cialis 80 mg http://rcialisgl.com/ – buy cialis online free shipping cheap cialis generic online

    May 15, 2021 at 18:00 | Report abuse | Reply
  3. BbshMile

    viagra price comparison https://loxviagra.com/ – india viagra similar to viagra

    May 15, 2021 at 20:08 | Report abuse | Reply
  4. AnooEncox

    aetna viagra coverage https://llviagra.com/ – viagra cost in thailand viapro vs viagra

    May 16, 2021 at 02:41 | Report abuse | Reply
  5. stornobrzinol

    I’ve read several excellent stuff here. Certainly worth bookmarking for revisiting. I wonder how a lot effort you place to make this sort of excellent informative website.

    http://www.stornobrzinol.com/

    May 16, 2021 at 08:24 | Report abuse | Reply
  6. Kenneth Greiwe

    I don't know about you people but I infatuated with airplanes. I had a friend in highschool that loves airplanes, so here are some airplane related stuff I don't know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2009/03/the-airline-blogs-livery-of-the-day-jetstar-2/

    http://www.pseconline.org/pipermail/reps_pseconline.org/2013-October/000980.html

    May 16, 2021 at 14:22 | Report abuse | Reply
  7. Dale Alhaddad

    Very nice article. I certainly love this site. Keep writing!

    https://extraproxies.com/tag/roteamento/

    May 16, 2021 at 15:44 | Report abuse | Reply
  8. LebnEncox

    24 hr pharmacy near me https://xlnpharmacy.com/ best online pharmacy india

    May 16, 2021 at 16:24 | Report abuse | Reply
  9. Marilou Pfeifle

    Have you ever heard of second life (sl for short). It is basically a online game where you can do anything you want. sl is literally my second life (pun intended lol). If you would like to see more you can see these sl websites and blogs

    http://myvedana.blogspot.com/2008/03/autism-in-second-life.html?m=0

    May 16, 2021 at 21:53 | Report abuse | Reply
  10. RebfZisse

    cialis online overnight http://rcialisgl.com/ cialis 20 mg tadalafil

    May 17, 2021 at 01:36 | Report abuse | Reply
  11. BbshMile

    otc viagra usa http://loxviagra.com/ – canadian viagra sales how long does it take for viagra to take effect

    May 17, 2021 at 14:17 | Report abuse | Reply
  12. JebgEncox

    online medicine to buy https://pharmacylo.com/ diabetes

    May 18, 2021 at 00:05 | Report abuse | Reply
  13. FmrfEncox

    cialis store in korea http://cialisee.com/ – order cialis in australia shopping cialis

    May 18, 2021 at 14:33 | Report abuse | Reply
  14. bonus veren siteler

    31957 390844Hello my family member! I wish to say that this post is incredible, excellent written and come with approximately all vital infos. I would like to see extra posts like this . 380009

    May 18, 2021 at 17:35 | Report abuse | Reply
  15. Linn Contras

    I don't know about you people but I infatuated with airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff I don't know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2009/07/delta-airlines-fined-375000-for-bumping/

    http://archive.constantcontact.com/fs151/1111846961938/archive/1119161431892.html

    May 19, 2021 at 01:41 | Report abuse | Reply
  16. LbsoZisse

    drugstore1st cialis https://ucialisdas.com/ 365 cialis

    May 19, 2021 at 06:13 | Report abuse | Reply
  17. Noble Hamparian

    I'm very pleased to uncover this great site. I need to to thank you for ones time for this fantastic read!! I definitely enjoyed every part of it and i also have you book marked to look at new things on your website.

    https://extraproxies.com/tag/d0bcd0b1/

    May 19, 2021 at 06:51 | Report abuse | Reply
  18. JebgEncox

    canadian pharmacy viagra 100mg https://pharmacylo.com/ cvs drugstore

    May 19, 2021 at 14:16 | Report abuse | Reply
  19. casino slot oyna

    63318 578693Paris Hilton: So lovely spending time with Manny and h 712139

    May 19, 2021 at 14:38 | Report abuse | Reply
  20. Timothy Roome

    Have you ever heard of second life (sl for short). It is basically a online game where you can do anything you want. Second life is literally my second life (pun intended lol). If you would like to see more you can see these sl websites and blogs

    http://myvedana.blogspot.com/2006/02/always-somewhere.html?m=0

    May 19, 2021 at 17:58 | Report abuse | Reply
  21. FmrfEncox

    cialis oral http://cialisee.com/ cialis before and after pictures

    May 20, 2021 at 06:56 | Report abuse | Reply
  22. Willy Resetar

    Have you ever heard of second life (sl for short). It is basically a game where you can do anything you want. SL is literally my second life (pun intended lol). If you want to see more you can see these second life websites and blogs

    http://myvedana.blogspot.com/2012/01/everyday.html

    May 20, 2021 at 14:07 | Report abuse | Reply
  23. GtnbCrulk

    viagra meme https://jokviagra.com/ is cialis better than viagra

    May 20, 2021 at 19:36 | Report abuse | Reply
  24. LebnEncox

    economy pharmacy Zofran cialis professional

    May 20, 2021 at 20:20 | Report abuse | Reply
  25. Pedro Costell

    I don't know about you people but I love airplanes. I had a friend in highschool that loves airplanes, so here are some airplane related stuff I don't know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2011/02/photo-boeing-747-8-intercontinental-all-wrapped-up/

    http://urlm.co/g/c/f/163871

    May 21, 2021 at 14:47 | Report abuse | Reply
  26. RebfZisse

    pakistan cialis https://rcialisgl.com/ – buy cialis with paypal cialis online canada paypal

    May 21, 2021 at 17:42 | Report abuse | Reply
  27. LbsoZisse

    price of cialis in pakistan https://ucialisdas.com/ cipla cialis

    May 21, 2021 at 17:53 | Report abuse | Reply
  28. LebnEncox

    online pharmacy without a prescription india pharmacy people's pharmacy

    May 22, 2021 at 07:06 | Report abuse | Reply
  29. live sgp hari ini

    922539 877409I enjoyed reading this a lot I truly hope to read a lot more of your posts in the future, so Ive bookmarked your blog. But I couldnt just bookmark it, oh no.. When I see quality websites like this 1, I like to share it with others So Ive created a backlink to your site (from 741707

    May 22, 2021 at 07:55 | Report abuse | Reply
  30. FmrfEncox

    cheap tablet cialis https://cialisee.com/ – cheap cialis buy cialis online

    May 22, 2021 at 16:41 | Report abuse | Reply
  31. Seymour Tesoro

    Have you ever heard of second life (sl for short). It is essentially a game where you can do anything you want. Second life is literally my second life (pun intended lol). If you want to see more you can see these Second Life articles and blogs

    http://rumblingstrips.blogspot.com/2009/04/

    May 23, 2021 at 02:13 | Report abuse | Reply
  32. RebfZisse

    cheap real cialis http://rcialisgl.com/ cialis none prescription

    May 23, 2021 at 02:41 | Report abuse | Reply
  33. JebgEncox

    mail order pharmacy https://pharmacylo.com/ cheap pharmacy online

    May 23, 2021 at 05:01 | Report abuse | Reply
  34. FmrfEncox

    discount generic cialis http://cialisee.com/ buy daily cialis from canada

    May 23, 2021 at 17:19 | Report abuse | Reply
  35. GtnbCrulk

    viagra canadian pharmacy ezzz http://jokviagra.com/ – viagra 100mg cost main ingredient in viagra

    May 23, 2021 at 22:30 | Report abuse | Reply
  36. BbshMile

    what drugs should not be taken with viagra? http://loxviagra.com/ como funciona el viagra

    May 24, 2021 at 03:02 | Report abuse | Reply
  37. LbsoZisse

    generic cialis canada https://ucialisdas.com/ cialis no prescription canada

    May 24, 2021 at 10:48 | Report abuse | Reply
  38. JebgEncox

    impotence http://pharmacylo.com/ Levaquin

    May 25, 2021 at 01:06 | Report abuse | Reply
  39. Zisseloh

    ordering cialis online https://rcialisgl.com/ – cialis paypal cialis without prescriptions canada

    May 25, 2021 at 23:35 | Report abuse | Reply
  40. EncoxGtv

    united states online pharmacy mood enhancing prescription drugs legitimate online pharmacy list

    May 26, 2021 at 00:01 | Report abuse | Reply
  41. EncoxHtf

    cialis for sale https://cialishav.com/ – cialis and high blood pressure cialis free samples

    May 26, 2021 at 21:42 | Report abuse | Reply
  42. CrulkAsd

    cialis without prescription https://cialisjla.com/ – cialis black cialis without perscription canada pharmacy

    May 27, 2021 at 01:14 | Report abuse | Reply
  43. ZisseVed

    online cialis australia https://krocialis.com/ – cialisblack dapoxetine and cialis together

    May 27, 2021 at 15:01 | Report abuse | Reply
  44. EncoxGtv

    canadian pharmacy 3 testosterone cream online pharmacy viagra online pharmacy reviews

    May 27, 2021 at 19:28 | Report abuse | Reply
  45. EncoxHtf

    cialis for young guys https://cialishav.com/ – black cialis 800mg cialis 5 mg tablet

    May 27, 2021 at 21:49 | Report abuse | Reply
  46. Delpha Cavaretta

    Have you ever heard of second life (sl for short). It is basically a online game where you can do anything you want. Second life is literally my second life (pun intended lol). If you would like to see more you can see these sl websites and blogs

    http://thisteachinglife.blogspot.com/2007/03/new-call-to-teach-basics.html

    May 28, 2021 at 02:50 | Report abuse | Reply
  47. EncoxAni

    pharmacy online store malaysia https://pharmacyken.com/ – canadian pharmacies in canada online medicine tablets shopping

    May 29, 2021 at 00:23 | Report abuse | Reply
  48. Mitzi Verdell

    Have you ever heard of second life (sl for short). It is basically a online game where you can do anything you want. Second life is literally my second life (pun intended lol). If you want to see more you can see these Second Life authors and blogs

    http://razakam.blogspot.com/2009/07/spiralling-descent.html

    May 29, 2021 at 03:02 | Report abuse | Reply
  49. EncoxDev

    popular prescription drugs Nizoral synvisc canadian pharmacies

    May 29, 2021 at 09:16 | Report abuse | Reply
  50. CrulkAsd

    cialis with dapoxitine https://cialisjla.com/ – cialis cena buy cialis ireland

    May 29, 2021 at 19:25 | Report abuse | Reply
1 2 3 4 5 6

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.