home
RSS
December 11th, 2012
02:57 PM ET

HIV helps put girl's leukemia in remission

An experimental treatment in which researchers reengineer a patient's own immune system to attack cancer cells seems to have worked in a 7-year old girl named Emma Whitehead. The acute lymphoblastic leukemia that almost claimed Whitehead's life is now in remission.

Whitehead received the treatment, called T-cell immunotherapy, in April. First doctors drew Whitehead's blood, separated out white blood cells called T-cells, and then, using a disabled AIDS virus to transmit genetic material, made the T-cells capable of identifying and attacking leukemia cells.

Finally, the genetically modified T-cells were transfused back into Whitehead, where they went to work wiping out her leukemia to below the level of detection, a process that can itself be deadly.

"This is just one example now of several examples where people can now use immune cells recognizing cancer to reject, and in some cases it's been well shown for 10 years now, that they can cure certain types of cancer with this approach," says Dr. James Yang, a senior investigator at the National Cancer Institute.

"This latest research is about one such retargeting. It's targeting a single molecule, CD-19, that's on certain types of cancers."

Whitehead is one of 12 patients to undergo T-cell immunotherapy for Leukemia at the University of Pennsylvania. Other patients have responded differently, or not at all, to the treatment.

Among them, another pediatric patient initially responded to the treatment, but relapsed one month later. When the leukemia came back, it no longer had the specific CD-19 receptor that doctors had engineered her T-cells to identify on leukemic cells.

"Very often, with acute leukemia when patients relapse, they relapse fairly quickly, and the longer that Emily and other patients go without a relapse, the better the chances the leukemia won't come back, but it is still early in the follow-up," says Dr. David Porter, one of the Penn researchers. Emily is Whitehead's given name, although her family calls her Emma.

"There's a great deal of energy and effort trying to identify other targets on leukemia cells for that situation, but also useful targets that could be on other cancers where you could apply this kind therapy," he said.

Other hospitals are trying similar therapies.


soundoff (760 Responses)
  1. truyen hinh truc tuyen thvl1

    Kết Quả Futsal Việt Nam Vs Lebanondemkhuya tvTheo thể thức thi đấu, đội thắng ở cặp đấu này sẽ giành tấm vé đến Lithuania trong ngày hội bóng đá lớn nhất thế giới mang đến futsal. Tuyển futsal Việt Nam bước vào trận play-off lượt đi tranh vé dự play-off World Cup 2021 với sự tự tin. Tuy vậy, HLV Phạm Minh Giang bày tỏ, toàn đội ko ngán Lebanon tuy nhiên sẽ tìm cách để khắc chế sức mạnh của đối thủ bởi trên băng ghế huấn luyện là nhà cầm quân Ramiro Lopez, người từng dẫn dắt futsal Tây Ban Nha.|Dựa vào lịch tranh tài, quý khách có thể sắp xếp công việc

    https://rucyprus.net/detail/thedotv-truc-tiep-94091.html

    June 12, 2021 at 16:29 | Report abuse | Reply
  2. hair salons near me

    An interesting discussion is definitely worth comment. There's no doubt that that you should publish more about this issue, it may not be a taboo subject but generally folks don't talk about these issues. To the next! Kind regards!!

    https://www.wilsonlearning.com/?URL=www.nearmyspot.com

    June 12, 2021 at 16:29 | Report abuse | Reply
  3. Malcom Rons

    Have you ever heard of second life (sl for short). It is essentially a online game where you can do anything you want. sl is literally my second life (pun intended lol). If you want to see more you can see these Second Life articles and blogs

    http://everydayliteracies.blogspot.com/2007/07/sunday-in-bottle-cove-newfoundland.html

    June 12, 2021 at 17:40 | Report abuse | Reply
  4. little caesars near me

    http://kearsarge.biz/__media__/js/netsoltrademark.php?d=bjsnearme.com

    June 12, 2021 at 19:01 | Report abuse | Reply
  5. appliance store near me

    http://marineart.com/__media__/js/netsoltrademark.php?d=masternearme.com/

    June 12, 2021 at 20:06 | Report abuse | Reply
  6. grocery near me

    http://galaxybotanical.com/__media__/js/netsoltrademark.php?d=bestlocalnearme.com/

    June 12, 2021 at 22:13 | Report abuse | Reply
  7. urgent care near me

    Great web site you have here.. Itís hard to find high-quality writing like yours nowadays. I truly appreciate individuals like you! Take care!!

    https://www.wrasb.gov.tw/opennews/opennews01_detail.aspx?nno=2014062701&return=http://bestshopnearme.com

    June 12, 2021 at 22:58 | Report abuse | Reply
  8. everton đấu với liverpool

    Tỷ Số Soccer Trực Tuyến Hôm Nayvtv3 hdTheo thể thức thi đấu, đội thắng ở cặp đấu này sẽ giành tấm vé đến Lithuania trong ngày hội bóng đá lớn nhất thế giới đến futsal. Tuyển futsal Việt Nam bước vào trận play-off lượt đi tranh vé dự play-off World Cup 2021 với sự tự tin. Tuy vậy, HLV Phạm Minh Giang bày tỏ, toàn đội không ngán Lebanon tuy nhiên sẽ tìm cách để khắc chế sức mạnh của đối thủ bởi trên băng ghế huấn luyện là nhà cầm quân Ramiro Lopez, người từng dẫn dắt futsal Tây Ban Nha.|Dựa vào lịch tranh tài, quý khách rất có thể sắp xếp công việc

    https://rucyprus.net/detail/vtv11-101391.html

    June 13, 2021 at 03:06 | Report abuse | Reply
  9. Evalyn Betenson

    I don't know about you people but I infatuated with airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff I don't know about you guys but I love airplanes. I had a friend in highschool that loved airplanes, so here are some airplane related stuff https://www.airlinereporter.com/2010/08/video-harrier-hovering-at-oshkosh-airventure-2010/

    http://www.hotfrog.com/search/mountlake-terrace2Cwa/freight

    June 13, 2021 at 04:12 | Report abuse | Reply
  10. kinkos near me

    https://www.lipperhey.com/en/www.hootnholler.net/

    June 13, 2021 at 09:36 | Report abuse | Reply
  11. shoe stores near me

    An outstanding share! I have just forwarded this onto a friend who had been doing a little homework on this. And he in fact ordered me lunch simply because I found it for him... lol. So let me reword this.... Thank YOU for the meal!! But yeah, thanks for spending time to discuss this matter here on your internet site.

    http://drivefinancial.info/__media__/js/netsoltrademark.php?d=www.bjsnearme.com

    June 13, 2021 at 09:58 | Report abuse | Reply
  12. fedex near me

    When I originally left a comment I appear to have clicked the -Notify me when new comments are added- checkbox and from now on whenever a comment is added I get 4 emails with the same comment. Is there an easy method you can remove me from that service? Thank you!

    http://truehits.net/webout.php?url=https://masternearme.com/

    June 13, 2021 at 12:39 | Report abuse | Reply
  13. dogs for sale near me

    Excellent post! We are linking to this particularly great content on our site. Keep up the good writing.

    http://www.chicagolog.net/__media__/js/netsoltrademark.php?d=bulknearme.com/

    June 13, 2021 at 13:02 | Report abuse | Reply
  14. kia dealership near me

    That is a good tip particularly to those new to the blogosphere. Simple but very accurate infoÖ Appreciate your sharing this one. A must read article!

    http://www.koloboklinks.com/site?url=https://www.socallandscapers.com

    June 13, 2021 at 23:56 | Report abuse | Reply
  15. thvl3

    Thẳng đá Bóng Ngày Hôm Nayhtv9 hdNếu cứ chơi như cơ hội vừa tiêu diệt Everton cho tới 3-1 trên Sảnh khách hàng

    https://virandoamor.com/detail/xoilac-tv-apk-moi-nhat-125651.html

    June 14, 2021 at 03:08 | Report abuse | Reply
  16. truc tiep vtv3

    Xem Trực Tiếp Bóng Đátính thuế fo4Theo thể thức thi đấu, đội thắng ở cặp đấu này sẽ giành tấm vé đến Lithuania trong ngày hội bóng đá lớn nhất thế giới cho futsal. Tuyển futsal Việt Nam bước vào trận play-off lượt đi tranh vé dự play-off World Cup 2021 với sự tự tin. Tuy vậy, HLV Phạm Minh Giang bày tỏ, toàn đội không ngán Lebanon tuy vậy sẽ tìm cách để khắc chế sức mạnh của đối thủ bởi trên băng ghế huấn luyện là nhà cầm quân Ramiro Lopez, người từng dẫn dắt futsal Tây Ban Nha.|Dựa vào lịch tranh tài, quý khách hoàn toàn có thể chuẩn bị xếp làm việc

    https://rucyprus.net/detail/thedo-tv-95013.html

    June 14, 2021 at 07:10 | Report abuse | Reply
  17. jobs near me

    https://baoviet.com.vn/Redirect.aspx?url=https://heatingairconditioningcontractorsanaheimhills.com

    June 14, 2021 at 09:17 | Report abuse | Reply
  18. locksmith near me

    Great information. Lucky me I discovered your site by accident (stumbleupon). I have book-marked it for later!

    http://lnfcu.com/helpers/choice.asp?h=shelbydaniellephotography.com/

    June 14, 2021 at 10:24 | Report abuse | Reply
  19. kenh letsviet vtc9

    Trực Tiếp Bóng Đá Hôm Nay, Links Xem Bóng Đá Trực Tuyến 24hlich phat song vtc4Theo thể thức thi đấu, đội thắng ở cặp đấu này sẽ giành tấm vé đến Lithuania trong ngày hội bóng đá lớn nhất thế giới cho futsal. Tuyển futsal Việt Nam bước vào trận play-off lượt đi tranh vé dự play-off World Cup 2021 với sự tự tin. Tuy vậy, HLV Phạm Minh Giang bày tỏ, toàn đội ko ngán Lebanon tuy nhiên sẽ tìm cách để khắc chế sức mạnh của đối thủ bởi bên trên băng ghế huấn luyện là nhà cầm quân Ramiro Lopez, người từng dẫn dắt futsal Tây Ban Nha.|Dựa vào lịch tranh tài, quý khách rất có thể chuẩn bị xếp việc làm

    https://arubaeducation.info/detail/bong-da-tren-kenh-nao-81591.html

    June 14, 2021 at 10:34 | Report abuse | Reply
  20. seafood restaurants near me

    https://pennergame.de/redirect/?site=http://ocrv.rocks/

    June 14, 2021 at 17:02 | Report abuse | Reply
  21. ymca near me

    https://www.devot-ee.com/?URL=https://ocrvpaintandservice.com/

    June 14, 2021 at 17:53 | Report abuse | Reply
  22. Sprinter Repair Shops Near Me

    http://www.scga.org/Account/AccessDenied.aspx?URL=ocrvcenter.com/rv-repair-shop-universal-city-california

    June 14, 2021 at 21:47 | Report abuse | Reply
  23. RV Repairs Near Me

    Great blog you have got here.. Itís hard to find quality writing like yours these days. I honestly appreciate individuals like you! Take care!!

    https://treasury.gov/cgi-bin/redirect.cgi/?https://realitateadealba.net/sistem-de-iluminat-inteligent-si-eficient-cu-fonduri-regio-la-cugir/

    June 15, 2021 at 02:52 | Report abuse | Reply
  24. RV Repair Shops Near Me Now

    https://www.dmca.com/Protection/Status.aspx?ID=edc817fd-d796-4c84-abb8-d1cb5b2e3719&refurl=https://ingenieurleistungenreiter.com/index.php?option=com_phocaguestbook&view=phocaguestbook&id=1&Itemid=4&t=1340&limitstart=84660

    June 15, 2021 at 03:31 | Report abuse | Reply
  25. Malcolm Hamonds

    Have you ever heard of second life (sl for short). It is basically a video game where you can do anything you want. SL is literally my second life (pun intended lol). If you would like to see more you can see these sl websites and blogs

    http://thethinkingteacherchronicle.blogspot.com/2011/11/

    June 15, 2021 at 05:05 | Report abuse | Reply
  26. milf cuckold

    Fantastic blog! Do you have any helpful hints for aspiring writers?
    I'm hoping to start my own site soon but I'm a little lost on everything.
    Would you advise starting with a free platform like
    Wordpress or go for a paid option? There are so many options out there that I'm totally
    confused .. Any suggestions? Appreciate it!

    June 15, 2021 at 06:18 | Report abuse | Reply
  27. RV Repair Huntington Beach

    I like reading a post that can make people think. Also, thank you for allowing for me to comment!

    http://crl.ucsd.edu/cgi-bin/ax.cgi?http://funnycat.tv/video/country-coach-allure-remodel/SRd_j5S7044

    June 15, 2021 at 11:13 | Report abuse | Reply
  28. RV Repair California

    http://asiawebdirect.com/customer/recommend/?url=ocrvcenter.com/rv-repair-shop-carlsbad-california

    June 15, 2021 at 11:20 | Report abuse | Reply
  29. RV Repair Shops Near Me Now

    After checking out a few of the articles on your site, I truly appreciate your technique of blogging. I saved as a favorite it to my bookmark website list and will be checking back soon. Please check out my website too and tell me your opinion.

    http://pennergame.de/redirect/?site=https://www.ocrvcenter.com/rv-repair-shop-rancho-palos-verdes-california/

    June 15, 2021 at 11:21 | Report abuse | Reply
  30. situs bola online

    Goood dayy very cool blog!! Man .. Beautiful .. Superb ..
    I will bookmarrk your blog and take the feeds also?
    I am satisfied tto seek out a llot oof useful info right here within the submit,
    we need work out extra strategies on this regard, thanks for sharing.

    . . . . .

    Here iss my site :: situs bola online

    June 15, 2021 at 16:39 | Report abuse | Reply
  31. xem bdtt

    Trực Tiếp Bóng Đá Hôm Nay, Links Xem Bóng Đá Trực Tuyến 24hlịch chiếu phim lotte đà nẵngTheo thể thức thi đấu, đội thắng ở cặp đấu này sẽ giành tấm vé đến Lithuania vào ngày hội bóng đá lớn nhất thế giới cho futsal. Tuyển futsal Việt Nam bước vào trận play-off lượt đi tranh vé dự play-off World Cup 2021 với sự tự tin. Tuy vậy, HLV Phạm Minh Giang bày tỏ, toàn đội không ngán Lebanon tuy nhiên sẽ tìm cách để khắc chế sức mạnh của đối thủ bởi trên băng ghế huấn luyện là nhà cầm quân Ramiro Lopez, người từng dẫn dắt futsal Tây Ban Nha.|Dựa vào lịch tranh tài, bạn có thể chuẩn bị xếp công việc

    https://questiontime.info/detail/i-bong-da-tivi-truc-tuyen-119989.html

    June 15, 2021 at 18:36 | Report abuse | Reply
  32. RV Repair Huntington Beach

    This is a topic that's close to my heart... Take care! Exactly where are your contact details though?

    http://www.noexcuselist.com/li/?url=www.ocrvcenter.com/motorhome-slide-out-repair-near-me/

    June 15, 2021 at 21:15 | Report abuse | Reply
  33. RV Repair Seal Beach

    Excellent site you've got here.. Itís difficult to find quality writing like yours nowadays. I truly appreciate individuals like you! Take care!!

    https://www.studivz.net/Link/Dereferer/?ocrvcenter.com/social-media

    June 15, 2021 at 21:29 | Report abuse | Reply
  34. lịch chiếu phim sctv

    Thẳng đá Bóng Việt Nam Vs Lebanon. Xem Truc Tiep Bong Da. Futsal Việt Namjuventus đấu với fiorentinaXem bóng đá trực tuyến Trực tiếp Odd BK vs Sarpsborg, 20h ngày 24/5, giải VĐQG Na Uy. Xem lịch phạt sóng thẳng soccer EURO thời điểm hôm nay được Webthethao update chủ yếu xác nhất.

    https://chiefscreolecafe.com/detail/bong-dang-mot-ngoi-truong-beat-130096.html

    June 15, 2021 at 23:20 | Report abuse | Reply
  35. RV Repair Nearby

    Everyone loves it when people come together and share opinions. Great website, stick with it!

    https://janeyleegrace.worldsecuresystems.com/redirect.aspx?destination=www.ocrvcenter.com/rv-repair-shop-carlsbad-california

    June 16, 2021 at 00:24 | Report abuse | Reply
  36. RV Repair Shops Nearby

    https://host2.mandel.com/__media__/js/netsoltrademark.php?d=www.ocrvcenter.com/rv-solar-panel-repair-near-me/

    June 16, 2021 at 03:09 | Report abuse | Reply
  37. RV Repair Shops Near My Location

    https://www.diversitybusiness.com/SpecialFunctions/NewSiteReferences.asp?NwSiteURL=https://www.ocrvcenter.com/rv-repair-shop-valley-village-california/

    June 16, 2021 at 06:46 | Report abuse | Reply
  38. RV Repair Shops Near Me Now

    https://www0.lufc.talent-sport.co.uk/?returnurl=https://www.ocrvcenter.com/rv-repair-shop-encino-california/

    June 16, 2021 at 06:56 | Report abuse | Reply
  39. bet188

    Xoilac Tv Thẳng Bóng Đá htv9hdĐội tuyển chọn futsal nước ta đã có một trận đấu chấp nhận được trước phe đối lập đầy sức mạnh Lebanon. Kết quả Bà Rịa-Vũng Tàu vs Bình Phước ngày hôm nay 18h00 ngày 5/5, Hạng nhất nước Việt Nam.

    https://thisisthegreenroom.com/

    June 16, 2021 at 07:17 | Report abuse | Reply
  40. RV Repair Santa Ana

    That is a great tip especially to those new to the blogosphere. Brief but very accurate informationÖ Many thanks for sharing this one. A must read article!

    https://ttf.sdsu.edu/?URL=panlab.com/en/products/heka?start=198120

    June 16, 2021 at 10:46 | Report abuse | Reply
  41. apartments for rent near me

    After exploring a few of the blog articles on your blog, I truly appreciate your way of writing a blog. I book marked it to my bookmark webpage list and will be checking back soon. Please check out my web site as well and tell me your opinion.

    https://eichenbaum.com/__media__/js/netsoltrademark.php?d=https://www.ocrvcenter.com/

    June 16, 2021 at 14:20 | Report abuse | Reply
  42. truyen hinh truc tuyen thvl1

    Trực Tiếp đá Bóng Việt Nam Vs Lebanon. Xem Truc Tiep Bong Da. Futsal Việt Namhtv2 trực tuyếnĐây có lẽ là ngôi trường hợp “của đi thay cho người" khá như ý đối với Ben McLemore. Thiếu chút nữa tay ném của Los Angeles Lakers đã có được thể gặp hiểm họa nghiêm trọng. Cập nhật kết quả trận nước Việt Nam vs Lebanon thuộc play-off vòng chủng loại Futsal World Cup 2021.

    https://murraystivoli.com/detail/giai-copa-6889.html

    June 16, 2021 at 16:38 | Report abuse | Reply
  43. restaurants near me open

    Very nice post. I definitely love this site. Thanks!

    http://wagrankings.com/__media__/js/netsoltrademark.php?d=ocrvcenter.com/

    June 16, 2021 at 18:03 | Report abuse | Reply
  44. thai restaurants near me

    https://nationaleggbank.com/__media__/js/netsoltrademark.php?d=http://ocrvcenter.com/

    June 16, 2021 at 18:39 | Report abuse | Reply
  45. xfinity store near me

    http://www.mei-group.net/__media__/js/netsoltrademark.php?d=ocrvcenter.com

    June 16, 2021 at 18:54 | Report abuse | Reply
  46. tractor supply near me

    Aw, this was an incredibly good post. Taking a few minutes and actual effort to produce a very good articleÖ but what can I sayÖ I hesitate a lot and never manage to get anything done.

    https://www.burgiengineers.net/__media__/js/netsoltrademark.php?d=https://ocrvcenter.com

    June 16, 2021 at 19:01 | Report abuse | Reply
  47. wawa near me

    https://streamlinerefi.com/__media__/js/netsoltrademark.php?d=http://ocrvcenter.com

    June 16, 2021 at 19:42 | Report abuse | Reply
  48. May nen khi puma

    Howdy! This is my 1st comment here so I just wanted to give a quick
    shout out and tell you I truly enjoy reading your blog posts.
    Can you recommend any other blogs/websites/forums that go over the
    same topics? Thanks for your time!

    June 16, 2021 at 22:28 | Report abuse | Reply
  49. RV Repair Santa Ana

    Hi, I do believe this is a great site. I stumbledupon it 😉 I'm going to come back yet again since i have saved as a favorite it. Money and freedom is the greatest way to change, may you be rich and continue to help other people.

    http://creativecommons.org/choose/results-one?field_attribute_to_url=http://ocrvcenter.com/motorhome-ac-repair-near-me/

    June 16, 2021 at 22:36 | Report abuse | Reply
  50. RV Repair Shop Near My Location

    Aw, this was an exceptionally good post. Spending some time and actual effort to create a great articleÖ but what can I sayÖ I put things off a lot and never seem to get nearly anything done.

    https://www.icewarp.cz/ru/downloads/redir/?link=www.ocrvcenter.com/rv-repair-shop-stevenson-ranch-california

    June 17, 2021 at 02:21 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.