June 27th, 2012
02:43 PM ET

FDA approves drug to treat some obese, overweight adults

Some people who suffer from chronic weight issues may soon get some help from a pill. 

The U.S. Food and Drug Administration Wednesday approved Belviq, or lorcaserin hydrochloride, to be combined with a reduced-calorie diet and exercise, for treatment of chronic weight problems.

Specifically, the FDA says, it is approved for overweight or obese adults who have one or more medical conditions due to their weight, such as high blood pressure, type 2 diabetes or high cholesterol.

The FDA says the drug works by activating a receptor in the brain that helps a person to eat less and still feel full.

In trials, 47% of patients without type 2 diabetes lost at least 5% of their body weight. By comparison, 23% of patients treated with placebo lost at least 5% of their weight. In people with type 2 diabetes, 38% of patients on Belviq lost at least 5% of their body weight compared to 16% on placebo, according to the FDA.

"The results overall are quite modest," said Dr. Melina Jampolis, a physician nutrition specialist and CNN's diet and fitness expert. "But most experts agree that even a 5% weight loss has significant implications in terms of reducing the risk of obesity associated diseases including heart disease and diabetes."

The FDA says the manufacturer of Belviq, Arena Pharmaceuticals, will be required to conduct six postmarketing studies, including a long term cardiovascular trial to assess the risk of heart attack and stroke.

CNNMoney: Arena surges on weight loss drug approval

The most common side effects of Belviq in non-diabetic patients include headache, dizziness and fatigue; and in diabetic patients low blood sugar and pain, according to the FDA.

soundoff (879 Responses)
  1. jurb

    although i understand both sides of the comments on this board, i do not agree with the FDA publicly announcing some new drug to battle obesity as there are so many overweight people who got the way they are due to poor diet and lack of/no exercise who see an article like this and think "great! all i have to do is get my hands on some of this and i'll lose weight!", and we all know that there are a lot of overweight people who will think just that. for those who are overweight due to a medical condition and/or medicine than please make sure to talk with your doctor about what medications you're taking and the side effects you are experiencing before hopping on any bandwagon for this (or any) new drug.

    June 27, 2012 at 17:31 | Report abuse | Reply
    • Fig1024

      At least 1/3 of all overweight people (if not more) are just too poor to afford healthy diet. Fast foods simply offer the cheapest possible way to feed yourself. And those poor people will not be able to afford some fancy new obesity drug anyway.

      June 27, 2012 at 17:45 | Report abuse |
    • Trish

      Jurb, I agree with you. I am an overweight person but I've worked in a pharmacy for the past 10 years. There is absolutely, 100%, without a doubt "NO" overnight cure to lose weight! I've tried a couple of the over the counter weightloss methods and not taken them like I was supposed to which was to follow all directions including eating right, drinking enough water and daily exercise I managed to take off about 5 lbs. in week. Well guess what people?! If you eat right, drink enough water and exercise daily you'll still lose that same 5 lbs. without buying these miracle weightloss cures!!!!! And if you keep doing this without taking the cures, you'll keep losing weight! Gastric bypass works...for a few years. I've seen a few people that had it and because they don't want to give up or miss good food and sodas they eventually started gaining or gain all their weight back. Yes, some people have health issues that make weightloss impossible, but for most of us it's a self-control and laziness issue. If you want to try a diet plan, the one I've seen work the best is the Weight Watcher's Points Plus system. Quite a few people close to me are trying this and all of them have lost significant amounts. Weight Watcher's isn't a cure, it's a way of life and it's not that hard once you figure it out as long as you have the mindset to stick to it. You don't give up anything, you just learn to tweak it to your favor.

      June 27, 2012 at 18:51 | Report abuse |
    • Nah

      fig: "At least 1/3 of all overweight people (if not more) are just too poor to afford healthy diet. Fast foods simply offer the cheapest possible way to feed yourself."

      Are you serious?

      Spending $5 per meal on fast food is monumentally more expensive than spending $2 on a home cooked meal. And that home cooked meal can include all the healthy food you want.

      June 27, 2012 at 19:19 | Report abuse |
    • Michael

      Fig1024 I hate to tell you, but that's the biggest excuse I've ever heard. As a college student I would eat on less than 30 dollars a week and that wasn't shopping at walmart. It's a matter of looking and seeing what on special that week. Sometimes pasta is buy one get one free. So I would make pasta with a big bag of frozen veggies and whatever meat was on sale. People are lazy, junk food is expensive. That is the only time I spent more than 30 dollars is when I decided to get oreos or something. Beans, grains, vegetables and a little meat goes a long way. Also as someone who worked in a nice restaraunt I saw a lot of overweight people they obviously have monney. They're eating out. What needs to happen is the U.S. needs to stop making excuses for them and forcing them to improve.

      June 27, 2012 at 19:23 | Report abuse |
    • RunningMan

      STAY OUT of FAST FOOD places and DONUT SHOPS! Buy ONLY lean meat and veggies at the grocery store. Cook yourself, don't be lazy. Snack on raw veggies if you get hungry, not junk food. . Get out and walk fast for 30 minutes every day. Do this and you will not be obese for long. This is not a biology or medical problem, stop making excuses. Never in the history of human evolution have we had so many fatsos. It is a Western cultural problem. A culture of couch-sitting, TV-watching, fast-food-munching laziness. Blame yourself, not your genes. And GET OFF THE COMPUTER NOW. Go exercise, fatty!

      June 27, 2012 at 19:43 | Report abuse |
    • Don

      It is cheaper to eat healthier than eat garbage. It might be more convenient to get fast food but surely not cheaper. Buying in bulk, shopping the adds and not wasting is the key if you have little money. If you spend $25 at MacDonalds you can get a lot of decent fruits, veggies and meat with the same amount and stretch it to more than one meal. Money is an excuse.

      June 27, 2012 at 19:59 | Report abuse |
    • DocBrown34

      Hi Jurb,
      I don't agree with part of your statement. FDA releases public information related to new drugs approvals in order to be transparent and keep the public informed. The FDA approves drugs based on safety and effectivness, and the benefits outweighing the risks of the drug. How the public and media outlets perceive this information is an entirely different thing altogether. I know FDA has some issues, but they aren't "announcing" anything here. This getting picked up and hyped by the media outlets, not FDA.

      June 27, 2012 at 20:37 | Report abuse |
  2. Cajun

    Yes, I want a double whopper everything on it, large fries and a DIET COKE!!!!!

    June 27, 2012 at 17:32 | Report abuse | Reply
    • lxNay

      I know, ironic. Still. having a diet coke is still hundreds of calories less than a regular coke and just cutting back on pop can significantly work toward reducing weight.

      June 27, 2012 at 17:42 | Report abuse |
    • Arnold

      I order the diet Coke with large fries and a double whopper. I don't have a weight problem, just prefer the taste of sweetener in diet coke over that of regular Coke. During my tour in Iraq, we had Coke bottled in Turkey and it tasted nothing like the Coke bottled in the US...different water treatment and sweeteners make a difference.

      June 27, 2012 at 17:59 | Report abuse |
    • ME

      ... Except that it appears that diet drinks mess up your metabolism and can still make you gain weight.

      June 27, 2012 at 18:05 | Report abuse |
    • willll

      In many other countries (dunno about Turkey) they use real cane sugar in their soft drinks instead of high fructose corn syrup. Tastes a lot better imo.

      June 27, 2012 at 18:06 | Report abuse |
    • dike

      coke with HFCS-which is bad and diet coke with cancer causing sweetner... no difference, still you'll die young either being fat or fat + cancer.

      June 27, 2012 at 18:07 | Report abuse |
    • Max Brooks from Florida

      Diet soda can actually be worse than regular soda because of all the artificial sweeteners that they are loaded with. You are better off skipping soda entirely.

      June 27, 2012 at 18:26 | Report abuse |
  3. BO Failed

    Is Michelle O going to beta test this drug?

    June 27, 2012 at 17:33 | Report abuse | Reply
    • Wow

      You are not a very intelligent human being.

      June 27, 2012 at 17:45 | Report abuse |
    • USian

      I'm sorry that your body odor has failed you, you might try a different deodorant. Of course, my statement makes as much sense as yours.

      June 27, 2012 at 18:06 | Report abuse |
  4. Melissa

    In other words, it doesn't work.

    June 27, 2012 at 17:34 | Report abuse | Reply
  5. Jon Gluvna

    I could get this even though my body fat percentage is pretty much normal. cause of my BMI!

    June 27, 2012 at 17:36 | Report abuse | Reply
  6. Elite Wellness

    America...wise up...stop eating processed foods and fast foods....eat food with nutritional value....lean white meats, vegetables and fruits!!!!

    June 27, 2012 at 17:36 | Report abuse | Reply
  7. Jay Sunleeh

    I do tae bo and zumba 3-4 times a week. I have a 1200 calorie diet I stick too, and I only drink water.

    That is to maintain my health. I am healthy but store fat. At 200 pounds I was at 17% body fat. Thats 45 pounds overweight for my height. The math doesnt add up.

    See you immediately assume everyone is built the same. Therefore, everything works for all people. It is simple minded.

    There is no miracle drug, miracle diet, miracle exercise program, just do what works for you.

    June 27, 2012 at 17:38 | Report abuse | Reply
    • ICU Nurse

      Yes!! I love your approach. Awesome!

      June 27, 2012 at 17:44 | Report abuse |
    • really?

      You are 100% correct in saying that everyone is built different, bodies react different, and that there is no one solution that works for everyone, etc. Unfotunatley, it is equally simple minded on your part to really try to convince someone that a 1200 calorie diet in addition to semi-rigorous exercise, will not help lose weight. Even in extreme glandular cases, the body simply cannot keep fat/weight on without the proper fuel (aka calories). I would recommend a closer/more honest assessment of your caloric intake or possibly using a more realistic example to support your argument. Your basis for comment is correct (everyone is differrent), but your supporting case simply does not make sense and is probably more phsychologically driven than it is factual (very common with this subject).

      June 27, 2012 at 18:50 | Report abuse |
  8. eroteme

    Why should we need Belviq? Has not Bloomberg solved our obesity problem with his demand to ban 32oz sugary sodas? Then on the other hand maybe we do need Belviq: there may be some obese who will drink two 16oz sugary sodas instead of one 32oz sugary soda, sending Bloomberg back to his medical drawing board, scratching his head.

    June 27, 2012 at 17:39 | Report abuse | Reply
  9. Ted

    Can anyone name one, just one "Weight Loss" (they used to be more sensitive, even when they were trying to kill you) Drug,
    that didn't result in Heart attacks, liver failure, high blood pressure, erectile dysfunction, wonky finger, oh no side boards and diarrhea?

    June 27, 2012 at 17:40 | Report abuse | Reply
  10. ICU Nurse

    Ah, the cure for putting too much in the mouth, is to put something else your mouth. How about we look to our feet to loose those extra pounds. Get up and move and groove to the music. Let's all dance. Get to know and love your body. It's been with your whole life. Use it.

    June 27, 2012 at 17:43 | Report abuse | Reply
    • Mike

      You are correct in that many people who are obese are that way because they need to move their bodies more. Most Americans are lazy, and I would agree that most overweight people are lazy and have poor eating habits. And while I think this drug really shouldn't be approved because 5% of one's body is really nothing if one is morbidly obese, there are those unlucky people out there who cannot lose weight no matter how much they change their life style. For example, people who take anti-depressants for years because they have a disorders that require them often suffer from weight gain because years and years of anti-depressants/anti-anxieties can destroy the function of your thyroid gland. There are many exceptions.

      June 27, 2012 at 17:49 | Report abuse |
    • eroteme

      Lets's all dance! I am a non-obese male. I tried dancing with a young obese lady a week or so ago. It was a bit of a struggle but I perservered.

      June 27, 2012 at 17:59 | Report abuse |
  11. Tamars

    when will the fda STOP rwarding pharmaceuticals and doctors for keeping human beings substance (dru) dependent? this insanity has to stop.

    June 27, 2012 at 17:44 | Report abuse | Reply
  12. Curmodgeon

    Let us clarify-–this drug will not help unless you exercise and diet.. That means 60-70% of the people it might help will not be helped because the reason they are obese is usually due to a poor diet and lack of exercise.

    June 27, 2012 at 17:45 | Report abuse | Reply
  13. Mike

    While I do understand the necessity of such drugs for people who are unable to lose weight (and those people are out there, no matter how much lifestyle change they go through), 5% of a person's body weight isn't enough to really market this as a success. Sorry, but it isn't. Also, most people who will take this drug are people who are lazy, people who give a bad name to those who would actually benefit from such a drug.

    June 27, 2012 at 17:46 | Report abuse | Reply
  14. Charles Darwin

    Obesity is on the nurture side of the nature vs. nurture scale.

    June 27, 2012 at 17:47 | Report abuse | Reply
    • will

      Medicines can nurture. Enough said.

      June 27, 2012 at 21:54 | Report abuse |
  15. Primal 4 Life

    Follow the Primal Blueprint and you will not need any of this nonsense. It's that simple and it wqil work for anyone who give it an honest go around.

    You will, lose weight without trying. You will, feel far more satisfied with your meals and eat less. You will, be able to leave you meds at the pharmacy where they belong.

    Give it a try, your health is your most important asset. Or you can take this pill which will do nothing but allow you to continue to make poor choices.

    June 27, 2012 at 17:48 | Report abuse | Reply
  16. lex

    I have been overweight (not obese, though) before and I didn't need a pill to help me lose weight. I decided that to lose the weight (about 30 lbs) I needed to eat when I was hungry and stop when I was full. I made sure to eat 3 meals a day that were nutritious and low in the bad fats. If I got hungry between meals I ate healthy snacks like fruits, veggies, nuts, etc. so that I wasn't starving all day. If I had a craving for something I ate a small portion of it. I also exercised for an hour a day. Guess what? I lost 30 lbs in 4 months. It's not rocket science.

    June 27, 2012 at 17:50 | Report abuse | Reply
  17. common sense

    So many people here saying just exercise and diet will solve everything... It is very hard to eat healthy when a family of 4 is living with $40k or less a year. Fruits and Veggies are definitely more expensive than past and bread.
    And, who's got time to exercise and work 2 jobs?!
    We don't need to just balance our diet, we need to balance our wealth.

    June 27, 2012 at 17:51 | Report abuse | Reply
    • Don

      Nobody makes people have more kids than they can afford.

      June 27, 2012 at 20:02 | Report abuse |
    • Dan

      Work smarter not harder.

      June 28, 2012 at 07:25 | Report abuse |
  18. bella

    no commets.

    June 27, 2012 at 17:52 | Report abuse | Reply
  19. Adipotide

    The real obesity drug will be here in 5 or 6 years hopefully. It is called adipotide. It destroys fat cells by killing the capillaries in them. The scientists that created it will likely win the Nobel prize.

    People need to bear in mind that many like myself use to eat terribly but wised up. We still have far more urges and terrible metabolism because new fat cells are created but never destroyed. They also constantly send your brain signals that you are hungry. With this drug, at least we can reset ourselves.

    June 27, 2012 at 17:55 | Report abuse | Reply
    • kotjmf

      you couldn't be more wrong.

      June 27, 2012 at 18:15 | Report abuse |
    • Saveallsharks

      Try a vegan lifestyle for 1 month and see the positive changes it makes to your body and it's drug free and cheaper than conventional eating!!

      June 27, 2012 at 19:18 | Report abuse |
  20. Shawn

    "To be combined with a reduced calorie diet and exercise."

    In other words, it's another sugar pill the drug companies are going to push on stupid people who think it is actually helping them. It's not the diet and exercise, oh no, it's the wonder drug! Here, take more of my money!

    June 27, 2012 at 17:56 | Report abuse | Reply
  21. dike

    just another vice that is being abused by cheap bad food. Tax all GMO's, sugar HFCS and fat. make fresh and healthy food cheap. it is all in the $$. Ban lobbyist (legal bribers and tugs) and people will do the right thing.

    June 27, 2012 at 17:58 | Report abuse | Reply
    • Don

      That's the typical liberal response. More government rules. More tax and spending. Pump money and regulations into a problem.

      June 27, 2012 at 20:05 | Report abuse |
  22. herpderp

    Hopefully it's cyanide.

    June 27, 2012 at 17:59 | Report abuse | Reply
  23. Adipotide

    Wrong Shawn. It helps you fend off hunger which assists you in sticking to your reduced calorie diet.

    June 27, 2012 at 17:59 | Report abuse | Reply
  24. Adipotide

    If anyone is struggling with hunger now I suggest low levels of ephedrine and or Ritalin. I believe you also can get prescription phentermine. Keep in mind all these can be dangerous stimulants if used incorrectly.

    June 27, 2012 at 18:01 | Report abuse | Reply
  25. skinsrock

    Yeah, but will it stop me from drinking a case of beer a week... That's where the cal's come from..

    June 27, 2012 at 18:04 | Report abuse | Reply
    • Don

      Why would you want to stop drinking a case a week? Sounds like you're doing ok to me!

      June 27, 2012 at 20:06 | Report abuse |
  26. Dizzyd

    There go the weight-loss sheeple again...let's beat up on the fat ppl again so we can feel superior! The diet industry really has you guys snookered. Just attack the fatties, everyone knows abuse is the way to help ppl...oh wait! That's right-those THINGS aren't ppl with feelings and such! I've got a suggestion – think for yourselves instead of letting the diet industry do it for you. Try reading 'The Obesity Myth' by Paul Campos.

    June 27, 2012 at 18:08 | Report abuse | Reply
    • LuisCamacho

      Right, because coddling and excuses has been working so well up until now (/sarcasm). This is not a superiority issue. My primary problem with obese people is that they continue to drive up the costs of health insurance, which everybody ends up paying for. I have no problem if you want to live your life as a sack of lard. Go for it. Its a free country. The problem starts when I'm expected to finance your unhealthy habits.

      June 27, 2012 at 18:44 | Report abuse |
  27. Daywalker_kyle

    Drugs cause more problems then they help solve and make a select class of businesses very wealthy. Any pill should be labeled a "gateway drug" because the cycle never ends. Treating symptoms and never the root problem. Pharma companies are happy all the while the health of the entire nation continues to erode. Healthy people are the number one enemy to Big Pharma. So yeah, keep on treating the symptom and don't enact a solution to address the problem and that is a long lasting lifestyle change. I'm amazed how people were able to live before "pills."

    June 27, 2012 at 18:08 | Report abuse | Reply
  28. pooch

    Seriously, those who argue they can't afford "healthy" food vs. fast food are just trying to justify a poor habit. The fact is this; I can make a healthy $10 meal composed of whole grain carbs, high quality protein and healthy fat that feeds my family for at least 2-days. In fact, I do this almost weekly. Fast food is not cheaper; it's simply easier. Now here's another fact: Fast food is tremendously more expensive in the long run as it slowly destroys the human body from the inside out. Think pharmaceutical drugs to manage your poor health are cheap? I didn't think so! Eat healthier, be healthier.

    June 27, 2012 at 18:09 | Report abuse | Reply
  29. philliyboy

    Can't afford to eat healthy? Excuses, excuses, oatmeal is cheap, whole grain rice is cheap, a bag of apples is cheap, water flows from the tap. Walk around the block costs $0.00. LAZY and STUPID!!

    June 27, 2012 at 18:11 | Report abuse | Reply
    • Johnnyboy

      apples are not cheap, unless you are buying them in bags, which half of them go bad within a day or two. Walking around the block does not burn enough calories to prevent obesity. You would really need a sustained activity for an hour or so. But I would hate to see a morbidly obese person attempt to run a marathon and have a heart attack just to make you happy.

      June 27, 2012 at 23:19 | Report abuse |
  30. Adipotide

    People didn't have such sedentary jobs in the past. You actually burned off the calories you consumed at work. Are you saying programmers that work all day so you can write your nasty comments here should have to exercise 3 hours when they come home just so they can stay thin like you?

    If you don't like the advancement of science and technology then go sign up with the Amish. Adipotide will be the CURE for many obesity problems and Type 2 diabetes.

    June 27, 2012 at 18:13 | Report abuse | Reply
    • Daywalker_kyle

      I'd be down for that. The advancement of science and technology is destroying the planet and it's inhabitants. That's why topics such as this get so much attention. Because obesity really is a serious problem, one that is not cured with "science and technology's" pill. It has a much more simple and natural solution. trying to get around the laws of nature only lead to a new problem being developed.

      June 27, 2012 at 18:42 | Report abuse |
    • LuisCamacho

      If you're spending three hours in the gym, and you're not a professional bodybuilder, then you're doing it wrong.

      June 27, 2012 at 19:03 | Report abuse |
  31. Adipotide

    The real problem isn't that health food is more expensive. The real problem is it tastes like crap.

    June 27, 2012 at 18:16 | Report abuse | Reply
    • Daywalker_kyle

      Pills taste much better. Especially if you chew them.

      June 27, 2012 at 18:35 | Report abuse |
    • Saveallsharks

      Hahahahahahah ya your miracle drug will help u as u continue to eat crap food..you are what u eat and there is no pill gonna help you with that...plus you pill poppers are destroying your kidneys and livers...eat healthy and exercise and get off the couch !!!!!

      June 27, 2012 at 19:24 | Report abuse |
  32. poofoo


    June 27, 2012 at 18:17 | Report abuse | Reply
  33. greybush

    I've seen this before...the fat guy will wash down his pills with a triple beef and triple cheese burger, extra large fries and a extra large Dr. Pepper and say "Thank your modern medicine!"

    June 27, 2012 at 18:24 | Report abuse | Reply
  34. WD

    Side effects include fatigue, diziness, fainting, dry mouth, constipation, stroke, cardiac arrest, seizures, urinary tract infections, and death.

    June 27, 2012 at 18:27 | Report abuse | Reply
  35. Adipotide

    Actually cocaine and meth are good for losing weight. It's just they are dopamine reuptake inhibitors and releasers and most people would not take them as prescribed.

    June 27, 2012 at 18:31 | Report abuse | Reply
  36. Adipotide

    By the way, you can get those same side effects if you ate too many leafy vegetables in one sitting. Many vegetables are alkaline and you could end up making your ph far too basic requiring a breathing machine.

    June 27, 2012 at 18:33 | Report abuse | Reply
    • Saveallsharks

      I only eat veggies and my side effects are weight loss, greater metabolism, way more energy, never sick, don't need pills not to mention the health benefits for my next 50 years...animal products are way to acidic which takes calcium from your bones to get your ph balance in check...top dairy consuming countries also are the top countries with osteoporosis !!! Dairy is the worst thing u could do to your body it's all lies lies lies !!!!!!!

      June 27, 2012 at 18:46 | Report abuse |
    • Adipotide

      You are eating your vegetables in proper amounts. Try a little experiment. Eat all the vegetables you would normally eat in a week in one sitting and if you're not dead in tomorrow then post back on this article.

      The point is you have to do things in moderation including taking medicine. You shouldn't abuse it and anything can cause side effects.

      June 27, 2012 at 18:49 | Report abuse |
    • Saveallsharks

      Luckily I can't eat all my meals for a week in one sitting hahahahahahah who can??? Try that with your weekly meat diet and let me know how that works out for ya !!!

      June 27, 2012 at 19:13 | Report abuse |
  37. Name*

    Where do you go to be a test person for weight lost drugs.

    June 27, 2012 at 18:44 | Report abuse | Reply
    • Cherries


      June 27, 2012 at 21:55 | Report abuse |
  38. Mike Johnson

    ... the best anti-obesity drug is called water ... water instead of soda .. less donuts and beer ... no candy etc ... but that would mean that people actually would need some will power.

    June 27, 2012 at 18:49 | Report abuse | Reply
    • Daywalker_Kyle

      I'm sure there is a pill for that though right? Will Power that is...

      June 27, 2012 at 19:03 | Report abuse |
    • Adipotide

      If you guys have never been obese then you have NO idea what you are talking about. Fat cells never die. They just shrink in size. They send hormonal signals to your brain telling you you're hungry constantly. Perhaps this drug will put obese people where you are with your hormonal signals.

      I really wish a machine could be hooked up to people like you and the same signals sent to your brain so you'd shut the f up.

      June 27, 2012 at 19:09 | Report abuse |
  39. Moderate1981

    When will our society look at the obesiety issue and see that it is either due to a medical condition (Yes it does happen) or because of (for what ever reason) a person making their own decision. People have a free will and I have no respect for your 'drug'. Just like anything else if the person is not seriously motivated they will not loose weight or gAin it right back. There is NO magic pill.

    June 27, 2012 at 18:52 | Report abuse | Reply
  40. Adipotide

    Adipotide is the magic pill. It will be here in 5 or 6 years.

    June 27, 2012 at 18:55 | Report abuse | Reply
  41. mikesmovieblog007

    How about getting help from a healthy diet and exercise?

    June 27, 2012 at 19:15 | Report abuse | Reply
    • Saveallsharks

      Hahahahahahahah that doesn't taste good and exercise is to much work...we need a magic pill so we can eat crap food while we sit our big asses on the couch to watch 8 hrs of tv a day...that's not to much to ask is it??? Hahahahahahahaha

      June 27, 2012 at 19:41 | Report abuse |
  42. Frank Fielder

    As a pharmacist, I flinched when I saw that this drug works by activating the serotonin 2c receptors. Lets hope this drug is properly engineered to enter only certain areas of the brain that control hunger. Activating the serotonin 2c receptors, also called 5-HT2C receptors, can be bad news. It is a receptor found to be involved in suicidal thoughts, depression and anxiety when activated. Wikipedia has a good, well referenced article on this receptor and the consequences of its activation, especially if this activation is chronic, as would be the case here. I would not be surprised if this drug is pulled from the market a year or so after its release to the general public. Only then, after millions of people start using a drug, do you see side effects not seen in the clinical trials. I wish Arena Pharmaceuticals good luck with this drug, but personally, I would be wary of trying it or recommending it to others knowing how it works.

    June 27, 2012 at 19:18 | Report abuse | Reply
    • Adipotide

      Good analysis. There is another drug on the market in Europe that does the same thing. You can currently order it from China online as well. I avoided it for the very reasons you mentioned.

      June 27, 2012 at 20:06 | Report abuse |
    • Don

      A pharmacist that isn't Asian? Wow!!

      June 27, 2012 at 20:09 | Report abuse |
  43. FloridaPoliticiansSuckBalls

    I have developed a new weight loss pill too. You take one a day then get your fat ... on a bike and cycle 34 miles every day to and from work. It doesn't even matter how much you eat. After one month you will quickly figure out what food is healthy and what is not. If it comes in a box it is probably not worth eating. Fruits and Vegetables and lots of them. Within six months my new pill will help you lose 20+ lbs guaranteed. Oh and there are no side effects from my pill cause it is made with SUGAR and about as effective as the garbage in this article.

    June 27, 2012 at 19:32 | Report abuse | Reply
  44. MinkMonks

    This pill already exists in generic form, it's called EDUCATION.

    June 27, 2012 at 19:37 | Report abuse | Reply
    • Saveallsharks

      Best comment of the day !!!!!!!!!

      June 27, 2012 at 19:47 | Report abuse |
    • Adipotide

      I know. The scientists that created Adipotide were very educated.

      June 27, 2012 at 20:17 | Report abuse |
  45. Ehhh

    I used to eat what was considered a fairly healthy and balanced diet, and worked out regularly and weight 175 pounds. I kept track of everything I ate. I aimed to eat 1400 calories a day. I worked out three times a week at the gym, and would walk 2-3 miles around my neighborhood on non-workout days. I couldn't seem to lose any more than a pound here or there. And if I went on vacation or the holidays came I would gain back whatever I lost in a week.

    Finally I went on a mostly plant based whole foods diet, and this was the first time I could lose weight. I lost 40 pounds in six months, I feel better than ever, and I just got back from the doctor and my blood pressure was 95/65, my cholesterol was 150, and triglycerides were 115. In the past my numbers were all in the normal ranges, but towards the high side of normal. Now they are all in the very low ranges.

    My theory is that genetically I hold onto weight. I can't eat pasta, processed food, dairy, or lots of meat. I'm eating a similar amount of calories as before, but the calories come from different places.

    Unfortunately, I make about 25k/year and I have had to totally rebudget my life to keep this lifestyle change. I spend at least twice as much on food as I did 6 months ago. It is a huge sacrifice, and my savings have taken a big hit. I feel that my health needs to be my number one priority, but I know if I take a financial hit this new diet is unsustainable. I used to eat things like pasta 5 times a week, and sandwiches with bread, lunch meat and a slice of cheese almost one meal a day. Those meals were less than a dollar, and cannot eat those things any more. Now I figure I spend $15/day to eat all of the fresh fruits and veggies that I eat now. I rarely eat at restaurants, so I'm not wasting money there.

    June 27, 2012 at 19:52 | Report abuse | Reply
    • Adipotide

      Just get some Bronkaid, take one pill a day divided up multiple times. Also take 1 to 2 tsp of baking soda a day mixed with water. DO NOT take it all at once as you will be to alkaloid.

      Try to slowly add vegetables and fruits to your diet along with chicken and fish or fish oil. Keep your calories around 2000 and make adjustments as time goes by.

      Don't take the Bronkaid for more than a few months before taking a break for a month or two. You could also experiment with Yohimbine. Yohimbine you can get from Amazon.com and Bronkaid you can get from your local drug store but you'll have to sign for it.

      June 27, 2012 at 20:14 | Report abuse |
  46. brian

    Go figure, FDA says medical marijuana has no medical use (even while not smoked) but handing out pills for lazy fat people is fine.

    June 27, 2012 at 20:04 | Report abuse | Reply
  47. RunningMan

    Do fruits and veggies cost more than bread and pasta? Probably. Do fruits band veggies cost more than DVD/BlueRay players, movie rentals, movie theatre tickets, Xboxes, iPods, cable/satellite TV bills, makeup and perfume, fancy sneakers, and all sorts of unnecessary things you will find in the budget of many "poor" obese people? No, they don't. They could have spent that money on eating healthier.Obesity is a choice for most people.

    Liberals like to 'fix' things with taxes. Perhaps we need to create a hefty national tax on obesity to help people make the right choice. Also ban fat people from movie theaters, donut shops, and the dessert isle at the grocery store. Seriously, if you want national health care, we just might have to do it. Welcome to socialism. Big brother will help you make better choices.

    June 27, 2012 at 20:08 | Report abuse | Reply
    • LuisCamacho

      I think you'd have more success approaching obesity the same way we went after smoking. Public education (starting young), national advertising campaigns, and a hefty dose of public shaming. Might also have to add in some sort of extra costs/inconveniences to really drive the point home, maybe things like charging extra airfare above a certain body fat percentage.

      June 27, 2012 at 20:32 | Report abuse |
    • Johnnyboy

      You are ridiculous, taxes have already been attempted to stop folks in major cities from drinking sodas. That doesn't work.

      June 27, 2012 at 23:22 | Report abuse |
  48. Adipotide

    Just get some Bronkaid, take one pill a day divided up multiple times. Also take 1 to 2 tsp of baking soda a day mixed with water. DO NOT take it all at once as you will be to alkaloid.

    Try to slowly add vegetables and fruits to your diet along with chicken and fish or fish oil. Keep your calories around 2000 and make adjustments as time goes by.

    Don't take the Bronkaid for more than a few months before taking a break for a month or two. You could also experiment with Yohimbine. Yohimbine you can get from Amazon.com and Bronkaid you can get from your local drug store but you'll have to sign for it.

    June 27, 2012 at 20:15 | Report abuse | Reply
  49. Mochi

    Pills now? Give me a break. People take too much everyday anyhow, and having one to reduce obesity is just absurd. I agree with everyone who said that education, fitness, and better eating is the more correct solution. Because it takes mental and emotional discipline to reduce weight. If an overweight person is relying on a single pill to get rid of that excess weight, than there's definitely a lack of something in there lives… perhaps self confidence? It's true, a person saying that they got rid of weight on their own through a good diet and squeezing more fitness into their lives (for crying out loud, stop the laziness and get on your feet people) honestly increases their self confidence. Ahh, that sounds way better.

    That's a good thing.

    June 27, 2012 at 20:25 | Report abuse | Reply
    • will

      Yet another idiot who thinks he knows that there's only one answer, and that answer cannot include medicine. Get an education, Mochi.

      June 27, 2012 at 21:57 | Report abuse |
  50. 22X Richer

    People! Stop putting quarter pounders and Whoppers in your mouth, get off the couch and the hip tires will ebb some. It is unbelievable that the US is possibly the fattest nation on planet earth. We have more recreational opportunity than most other nations yet we do nothing but eat while we watch the stupid box.

    Abundance has caused us to live to eat not eat to live.

    June 27, 2012 at 20:26 | Report abuse | Reply
    • Cherries

      I second those motions!

      June 27, 2012 at 20:40 | Report abuse |
    • Johnnyboy

      That is myth, overweight folks do not eat quarter ponders, It is more of the fact that folks don't eat consistent meals. I gained my weight when I stopped eating breakfast regularly and overate when I got food.

      June 27, 2012 at 23:17 | Report abuse |
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