home
RSS
Researcher: Blood test for early-onset depression promising
April 17th, 2012
02:44 PM ET

Researcher: Blood test for early-onset depression promising

How does a parent know if their child or teen is experiencing normal adolescent sadness or moodiness or - a more serious form of depression? The answer may one day lie in a simple blood test, if the results of a new early study are confirmed in larger populations.

The results are published in Translational Psychiatry.

Early-onset major depressive disorder is a mental illness that affects people under 25. While about 2 to 4% of cases are diagnosed before adolescence, the numbers skyrocket to 10-25% with adolescence, explains lead researcher Eva Redei, professor of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine.

Why it matters

“Not diagnosed, depression affects how teens relate to others.  The No. 1 cause of death among the depressed is suicide,” explains Redei. “If teens are depressed and not treated, there can be drug abuse, dropping out of school.  Their whole lives can depend on these crucial and vulnerable years.”  Depression typically continues into adulthood, says Redei,  so catching it early allows for proper treatment.

The research

Redei’s research team discovered eleven blood biomarkers for early-onset major depression.  Their original work used rats, and they confirmed their results in this small study of humans that included 14 teens with major depressive disorder, and 14 teens without depression.  The researchers discovered that they could distinguish between major depression with anxiety and without anxiety, based upon the genetic markers.

“Having an objective test that tells a physician there is a physical, genetic explanation for depression”  allows them to treat patients with a precise diagnosis, Redei explains.  "Knowing there is an objective reason for their child’s feelings can allow parents and children to understand that depression is an illness, it’s a complicated illness, that is very common, and can be treated.”

What's next?

She hopes that having a science-based diagnosis will eliminate some of the stigma associated with mental illness. After more testing, these findings hopefully “may help psychiatrists to predict which treatments will be efficient, based on the biomarkers."

"It won’t be in the clinic this year, but assuming the resources are available, then it is going to happen.”


soundoff (92 Responses)
  1. tadalafil 30 mg

    elevex 20 mg tadalafil 60 mg for sale tadalafil com

    February 19, 2021 at 14:27 | Report abuse | Reply
  2. SocialMedia Services2021

    Social network traffic Facebook likes Twitter Followers Instagram Followers and much more. Our Website: https://smmsupreme.com/

    https://bit.ly/2Hnl7vE

    February 19, 2021 at 17:28 | Report abuse | Reply
  3. aralen uk

    who makes chloroquine phosphate chloroquine diphosphate does chloroquine work

    February 20, 2021 at 14:26 | Report abuse | Reply
  4. zithromax online

    z pak wiki zithromax 500 mg zithormax

    February 21, 2021 at 20:25 | Report abuse | Reply
1 2

Leave a Reply to chris


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.