home
RSS
Opium study raises questions about painkillers
Farmers harvest the opium sap from the poppy plant in Fayzabad, Badakhshan, Afghanistan.
April 17th, 2012
06:31 PM ET

Opium study raises questions about painkillers

About 20 million people are using the drug opium or one of its derivatives. A new study suggests new reasons for viewing this as problematic.

Research in the British Medical Journal finds strong connections between people using opium and conditions such as cancer, circulatory diseases and respiratory conditions.

"Long term recreational opioid use, even at relatively modest levels, causes important increases in death from multiple different causes," said study co-author Paul Brennan, head of the Section of Genetics at the International Agency for Research on Cancer in Lyon, France.

Why it matters

Although this study focused on opium for recreational purposes, the research also has significant implications for medicinal uses of opium-derived painkillers - such as morphine and codeine, Irfan Dhalla, assistant professor at St. Michael's Hospital in Toronto, wrote in an accompanying editorial.


Dhalla points out that a separate study in the United States on osteoarthritis patients found a nearly two-fold mortality increase among those who used opioids compared to those who took non-steroidal anti-inflammatory drugs. Other research supports the conclusion that there's a risk apart from the chance of accidental overdose.

These risks are still not entirely understood, and more research is needed to determine exactly what's going on here.

"For the management of chronic non-cancer pain, a better prescription may be caution," Dhalla writes.

The research 

The authors used information from more than 50,000 people in northeastern Iran, who enrolled in the study between January 2004 and June 2008. At the time they entered the study, participants' ages ranged from 40 to 75. Researchers recorded opium use and other factors, and followed most of these people until May 2011.

Researchers adjusted for variables such as poverty and cigarette smoking, which could have otherwise influenced the health outcomes of the participants. They still found an 86% increased likelihood of death from major causes among people who used opium.

The study's design - observing patient's outcomes but not randomly assigning them to use opium or not - cannot prove that opium causes the death risk.

But the authors were unable to find any alternative explanation. The effects were similar in men and women, in smokers and non-smokers, and in people who live in urban and rural communities. Taking opium orally and smoking it both carried similar risks.

Also, most users who participated in this study did not begin taking opium because of a pre-existing illness, Brennan said.


soundoff (980 Responses)
  1. Digital Marketing Event

    https://kinobusiness.com/bitrix/redirect.php?event1=news_out&event2=2Fupload2Fiblock2F1622FAvanpost-_-reliz.docx&event3=D090D0B2D0B0D0BDD0BFD0BED181D182+-+D180D0B5D0BBD0B8D0B7.docx&goto=http3A2F2Faffordableranking.com

    May 9, 2021 at 06:47 | Report abuse | Reply
  2. Seo Marketing Quotes

    I must thank you for the efforts you've put in penning this website. I really hope to see the same high-grade blog posts from you later on as well. In fact, your creative writing abilities has inspired me to get my own, personal blog now 😉

    http://www.st.sparneuwagen.de/index.php?action=click&isApp=0&url=http3A2F2Faffordableranking.com

    May 9, 2021 at 10:08 | Report abuse | Reply
  3. Cooper

    Thank you for any other informative blog. The place else
    may just I get that type of info written in such a perfect way?

    I have a project that I'm just now running on, and I've been at the
    look out for such information.

    May 9, 2021 at 10:37 | Report abuse | Reply
  4. Social Media Marketing Shop

    Pretty! This has been an incredibly wonderful article. Many thanks for supplying this information.

    http://kudzuenterprises.com/__media__/js/netsoltrademark.php?d=www.affordableranking.com

    May 9, 2021 at 13:42 | Report abuse | Reply
  5. RV Dashboard Los Angeles

    I like it when people come together and share opinions. Great blog, stick with it!

    https://bonus-books.com/rv-repair-near-me-86/

    May 9, 2021 at 15:27 | Report abuse | Reply
  6. Digital Marketing Specialists

    http://www.jagwareposingsuits.com/__media__/js/netsoltrademark.php?d=affordableranking.com

    May 9, 2021 at 16:12 | Report abuse | Reply
  7. RV Windows Orange County

    Good blog you have here.. It’s difficult to find excellent writing like yours nowadays. I truly appreciate people like you! Take care!!

    http://a.srvtwelve.com/internal/clicktrack?aid=&fd=http3A2F2Focrvcenter.com&req=i-719853296227524901567035013.196357C07C

    May 9, 2021 at 22:39 | Report abuse | Reply
  8. Internet Marketing Agency Near Me

    https://giloventures.com/__media__/js/netsoltrademark.php?d=affordableranking.com

    May 9, 2021 at 22:59 | Report abuse | Reply
  9. Emiko Luckey

    Have you ever heard of second life (sl for short). It is basically a game where you can do anything you want. SL is literally my second life (pun intended lol). If you would like to see more you can see these sl articles and blogs

    http://everydayliteracies.blogspot.com/2017/04/spanish-language-edition-of-of-new.html?showComment=1528150064412&m=0

    May 10, 2021 at 07:27 | Report abuse | Reply
  10. สล็อต

    The good think and so excellent with me thanks

    https://slot-191.com//สล็อต-slotxo-joker123-สล็อตแปะแมวทุน100/

    May 10, 2021 at 11:55 | Report abuse | Reply
  11. Content Marketing Agency Orange County

    Hello there! I simply wish to offer you a huge thumbs up for the excellent information you have got right here on this post. I am coming back to your web site for more soon.

    https://portal.estrechy.cz/redir.php?url=affordableranking.com

    May 10, 2021 at 16:55 | Report abuse | Reply
  12. Digital Marketing Consultant

    The next time I read a blog, Hopefully it doesn't disappoint me as much as this one. I mean, I know it was my choice to read through, but I actually believed you would probably have something interesting to talk about. All I hear is a bunch of complaining about something you could possibly fix if you weren't too busy looking for attention.

    http://brazner.com/__media__/js/netsoltrademark.php?d=affordableranking.com

    May 10, 2021 at 21:04 | Report abuse | Reply
  13. Internet Marketing Store

    Can I simply say what a relief to discover somebody that genuinely knows what they're talking about online. You actually understand how to bring an issue to light and make it important. More and more people really need to look at this and understand this side of your story. I was surprised you aren't more popular since you definitely possess the gift.

    http://kebrt.webz.cz/download.php?url=http://affordableranking.com

    May 10, 2021 at 21:55 | Report abuse | Reply
  14. Digital Marketing Event

    http://figure8realty.com/__media__/js/netsoltrademark.php?d=affordableranking.com

    May 11, 2021 at 00:59 | Report abuse | Reply
  15. Digital Marketing Programs

    I want to to thank you for this good read!! I absolutely loved every bit of it. I have you book-marked to look at new stuff you post…

    http://www.niklasdorf.eu/?Lgg=de&ToSite=affordableranking.com

    May 11, 2021 at 02:38 | Report abuse | Reply
  16. Seo Marketing Quotes

    http://www.hirek.hu/click.php?link=http://affordableranking.com

    May 11, 2021 at 04:32 | Report abuse | Reply
  17. Local Marketing Association Near Me

    A motivating discussion is worth comment. I do believe that you ought to publish more on this subject, it might not be a taboo matter but typically people do not talk about these issues. To the next! All the best!!

    http://www.charoittravel.ru/bitrix/rk.php?goto=http://www.affordableranking.com

    May 11, 2021 at 04:50 | Report abuse | Reply
  18. Video Marketing Companies Near Me

    http://integratingmindandbody.net/__media__/js/netsoltrademark.php?d=affordableranking.com

    May 11, 2021 at 06:33 | Report abuse | Reply
  19. Google Marketing Specialists

    A motivating discussion is definitely worth comment. I believe that you should write more about this issue, it might not be a taboo matter but usually folks don't speak about these issues. To the next! Many thanks!!

    http://hotvote.com/__media__/js/netsoltrademark.php?d=affordableranking.com

    May 11, 2021 at 07:25 | Report abuse | Reply
  20. rv air conditioner repair near me

    http://cc.toast.com/cc?a=godo&m=1&pr=pc&pid=&u=http://youtube.com/watch?v=_Uq6Alh1_8k&ts=1523474038.431

    May 11, 2021 at 19:22 | Report abuse | Reply
  21. Faye Daine

    This was great! I would like you to clean up all this spam though

    https://www.linkedin.com/in/yusuf-hanafy-82493b183

    May 11, 2021 at 20:40 | Report abuse | Reply
  22. certified rv repair

    This site was... how do you say it? Relevant!! Finally I've found something which helped me. Kudos!

    http://web2.sups.tp.edu.tw/school/netlink/hits.php?id=207&url=http://youtube.com/watch?v=NEistTyDq9Q

    May 11, 2021 at 21:13 | Report abuse | Reply
  23. RV Beds Los Angeles

    https://www.10tvtogo.mobi/__media__/js/netsoltrademark.php?d=g.page/OCRVFleetServices

    May 11, 2021 at 21:21 | Report abuse | Reply
  24. auto paint supply orange county

    The next time I read a blog, Hopefully it won't disappoint me just as much as this one. I mean, Yes, it was my choice to read through, but I truly thought you would have something helpful to talk about. All I hear is a bunch of crying about something that you can fix if you weren't too busy searching for attention.

    https://www.sibur.ru/bitrix/rk.php?goto=https://ocrvcenter.info/rv-repair-shop-south-el-monte-california

    May 12, 2021 at 00:06 | Report abuse | Reply
  25. cabinet repair service near me

    An outstanding share! I've just forwarded this onto a coworker who was doing a little homework on this. And he in fact ordered me dinner simply because I stumbled upon it for him... lol. So allow me to reword this.... Thank YOU for the meal!! But yeah, thanks for spending the time to discuss this matter here on your web page.

    http://kasugai.genki365.net/gnkk06/common/redirect.php?url=https://ocrv.biz/earthroamer-rv-collision-repair-paint-shop-near-me-orange-county

    May 12, 2021 at 01:00 | Report abuse | Reply
  26. RV Slide Out Orange County

    https://www.wescomfinancial.com/info/redirect.aspx?url=https://www.youtube.com/channel/UChUH5GdtSzHx6V02C90mnfQ/videos

    May 12, 2021 at 02:42 | Report abuse | Reply
  27. Juliann Gloston

    https://www.letterballoons.net

    May 12, 2021 at 03:59 | Report abuse | Reply
  28. rv blinds repair

    Saved as a favorite, I like your blog!

    https://www.newsletter.viamedica.pl/lt.php?c=1282&m=2481&nl=6&lid=20647&l=https://theocrv.com/toy-hauler-trailer-collision-repair-shop-near-me

    May 12, 2021 at 05:57 | Report abuse | Reply
  29. Frieghtliner Sprinter Abs Module Repair

    Excellent article. I am dealing with a few of these issues as well..

    https://d.agkn.com/pixel/2389/?che=2979434297&col=22204979,1565515,238211572,435508400,111277757&l1=https://fleetvehiclerepairshop.com/leisure-travel-van-repair-shop-near-me

    May 12, 2021 at 07:14 | Report abuse | Reply
  30. Repair Dash Ac Vents Sprinter

    https://www.dbta.com/Events/updateStats.aspx?id=1598&lnk=https://boxtruckrepairshop.com/touring-van-repair-shop-near-me

    May 12, 2021 at 16:51 | Report abuse | Reply
  31. RV Cabinet Riverside

    I could not refrain from commenting. Exceptionally well written!

    http://www.stydend.ru/go.php?site=http://www.yelp.com/biz/ocrv-center-anaheim-4

    May 12, 2021 at 17:22 | Report abuse | Reply
  32. Fiberglass Van Roof Repair

    Your style is very unique compared to other folks I've read stuff from. Thanks for posting when you've got the opportunity, Guess I will just bookmark this site.

    https://go.onelink.me/v1xd?pid=Patch&c=Mobile Footer&af_web_dp=https://sprintervanrepairshop.com/semi-truck-dent-repair-shop-near-me

    May 12, 2021 at 18:12 | Report abuse | Reply
  33. Jameslar

    Canned Heat Future Blues Rick Hayward Rick Hayward Stephen Whynott From Philly To Tablas

    May 12, 2021 at 19:29 | Report abuse | Reply
  34. box truck roof repair

    http://www.mnogosearch.org/redirect.html?https://youtube.com/watch?v=k4-6fPlUQCw

    May 12, 2021 at 19:46 | Report abuse | Reply
  35. Mercedes Benz Sprinter Repair Shop

    Pretty! This has been an extremely wonderful post. Thanks for providing these details.

    https://rosreestr.gov.ru/bitrix/redirect.php?event1=&event2=&event3=&goto=https://sprintervanrepairshop.com/semi-truck-body-shop-near-me

    May 12, 2021 at 20:23 | Report abuse | Reply
  36. RV TV Orange County

    http://www.community.kpro.co.in/home/leaving?target=http://yelp.com/biz/ocrv-center-anaheim-23dE0rLy

    May 12, 2021 at 20:35 | Report abuse | Reply
  37. rv wraps near me

    http://sendfwd.com/__media__/js/netsoltrademark.php?d=ocrv.xyz/rv-repair-shop-jurupa-valley-california

    May 12, 2021 at 21:11 | Report abuse | Reply
  38. RV Couches California

    http://magle.dk/music-forums/redirect-to/?redirect=http://g.page/ocrvcenter

    May 12, 2021 at 22:34 | Report abuse | Reply
  39. how to repair a slide out on a travel trailer

    http://ad.sxp.smartclip.net/optout?url=https://theocrv.com/rv-awning-repair-near-me

    May 13, 2021 at 07:40 | Report abuse | Reply
  40. RV Parts Near Me

    Great information. Lucky me I found your blog by accident (stumbleupon). I have saved it for later!

    http://in.klery.com/__media__/js/netsoltrademark.php?d=

    May 13, 2021 at 09:14 | Report abuse | Reply
  41. Jameslar

    Queen Studio Collection Slim Willis Band Wine Me Up Baby I Sayed That Queen Sheer Heart Attack

    May 13, 2021 at 12:34 | Report abuse | Reply
  42. Mercedes Benz Sprinter Body Repair San Diego

    http://web.trailerpark.com/__media__/js/netsoltrademark.php?d=fleetvehiclerepairshop.com/mercedes-luxury-van-repair-shop-near-me

    May 13, 2021 at 13:19 | Report abuse | Reply
  43. upholstery repair shop near me

    Good post. I learn something totally new and challenging on websites I stumbleupon on a daily basis. It's always useful to read through content from other writers and use something from their websites.

    https://dsu.regione.marche.it/Logout.aspx?Returnurl=https://ocrv.vip/motorhome-mattress-repair-near-me

    May 13, 2021 at 15:39 | Report abuse | Reply
  44. Los Angeles Sprinter Repair

    https://eao.rtrs.ru/go/?q=https://ocrvfleetservices.com/cargo-van-conversion-shop-near-me

    May 13, 2021 at 15:43 | Report abuse | Reply
  45. rv camping in orange county ca

    https://ads.homedy.com/ads/click?id=79&url=https://ocrv.org/rv-repair-shop-redlands-california

    May 13, 2021 at 15:53 | Report abuse | Reply
  46. RV Remodel Los Angeles

    http://www.reparan.com/__media__/js/netsoltrademark.php?d=

    May 13, 2021 at 18:34 | Report abuse | Reply
  47. rv awning replacement near me

    https://www.export.org.au/Redirect.aspx?destination=http://youtube.com/watch?v=jVBjGJWafng

    May 13, 2021 at 19:42 | Report abuse | Reply
  48. truck shop orange county

    https://tapestry.tapad.com/tapestry/1?ta_partner_id=950&ta_redirect=https://ocrvshop.com/delivery-truck-collision-repair-shop-near-me

    May 13, 2021 at 22:11 | Report abuse | Reply
  49. Jameslar

    The Billy Childish The 1982 Cassetes Various Baby Driver Music From The Motion Picture The Doobie Brothers Stampede

    May 13, 2021 at 22:26 | Report abuse | Reply
  50. redtube store

    Hi! I could have sworn I’ve been to this web site before but after browsing through some of the articles I realized it’s new to me. Regardless, I’m certainly delighted I discovered it and I’ll be bookmarking it and checking back frequently!

    http://emktg.cihi.ca/UrlTracking.aspx?em_key=08jafBPP2lWZoOqmzY/BzF3hFU9jQvN9pRYQwdGchCoOfLXGIWW6Y6UWEMHRnIQqHYmVVeX23ik5bqfdhCmHXL3vARe3YTEE&em_url=https://ocrv.pro/motorhome-seats-repair-near-me

    May 13, 2021 at 23:53 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Leave a Reply to RV Repair Shops Near My Location


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.