home
RSS
Opium study raises questions about painkillers
Farmers harvest the opium sap from the poppy plant in Fayzabad, Badakhshan, Afghanistan.
April 17th, 2012
06:31 PM ET

Opium study raises questions about painkillers

About 20 million people are using the drug opium or one of its derivatives. A new study suggests new reasons for viewing this as problematic.

Research in the British Medical Journal finds strong connections between people using opium and conditions such as cancer, circulatory diseases and respiratory conditions.

"Long term recreational opioid use, even at relatively modest levels, causes important increases in death from multiple different causes," said study co-author Paul Brennan, head of the Section of Genetics at the International Agency for Research on Cancer in Lyon, France.

Why it matters

Although this study focused on opium for recreational purposes, the research also has significant implications for medicinal uses of opium-derived painkillers - such as morphine and codeine, Irfan Dhalla, assistant professor at St. Michael's Hospital in Toronto, wrote in an accompanying editorial.


Dhalla points out that a separate study in the United States on osteoarthritis patients found a nearly two-fold mortality increase among those who used opioids compared to those who took non-steroidal anti-inflammatory drugs. Other research supports the conclusion that there's a risk apart from the chance of accidental overdose.

These risks are still not entirely understood, and more research is needed to determine exactly what's going on here.

"For the management of chronic non-cancer pain, a better prescription may be caution," Dhalla writes.

The research 

The authors used information from more than 50,000 people in northeastern Iran, who enrolled in the study between January 2004 and June 2008. At the time they entered the study, participants' ages ranged from 40 to 75. Researchers recorded opium use and other factors, and followed most of these people until May 2011.

Researchers adjusted for variables such as poverty and cigarette smoking, which could have otherwise influenced the health outcomes of the participants. They still found an 86% increased likelihood of death from major causes among people who used opium.

The study's design - observing patient's outcomes but not randomly assigning them to use opium or not - cannot prove that opium causes the death risk.

But the authors were unable to find any alternative explanation. The effects were similar in men and women, in smokers and non-smokers, and in people who live in urban and rural communities. Taking opium orally and smoking it both carried similar risks.

Also, most users who participated in this study did not begin taking opium because of a pre-existing illness, Brennan said.


soundoff (839 Responses)
  1. RV Repair Garden Grove

    Everything is very open with a precise explanation of the challenges. It was really informative. Your website is very useful. Thanks for sharing!

    http://neurostar.com/en/redirect.php?url=ocrvcenter.com/construction-truck-collision-repair-shop-near-me

    June 17, 2021 at 04:42 | Report abuse | Reply
  2. motels near me

    Hello there! This article could not be written much better! Looking through this post reminds me of my previous roommate! He constantly kept talking about this. I will send this article to him. Fairly certain he'll have a good read. I appreciate you for sharing!

    http://gppl.ca/EN/index/notification/notification-page.html?url=www.ocrvcenter.com/

    June 17, 2021 at 04:56 | Report abuse | Reply
  3. Camper Repair Shops Near Me

    https://www.fhwa.dot.gov/reauthorization/reauexit.cfm?link=ocrvcenter.com/rv-restoration-near-me

    June 17, 2021 at 05:42 | Report abuse | Reply
  4. food lion near me

    Very good article. I'm dealing with a few of these issues as well..

    https://dns.parkpage.foundationapi.com/__media__/js/netsoltrademark.php?d=http://www.ocrvcenter.com/

    June 17, 2021 at 07:41 | Report abuse | Reply
  5. download wukong333

    If you desire to get much from this paragraph then you have
    to apply these methods to your won weblog.

    My web page ... download wukong333

    June 17, 2021 at 08:34 | Report abuse | Reply
  6. RV Repairs Near My Location

    Good web site you have got here.. Itís difficult to find good quality writing like yours nowadays. I seriously appreciate people like you! Take care!!

    http://otohits.net/home/redirectto?url=http://www.ocrvcenter.com/rv-repair-shop-glendora-california/

    June 17, 2021 at 09:36 | Report abuse | Reply
  7. RV Repair Shop Near My Location

    http://rs.rikkyo.ac.jp/rs/error/ApplicationError.aspx?TopURL=https://ocrvcenter.com/rv-repair-shop-signal-hill-california

    June 17, 2021 at 10:43 | Report abuse | Reply
  8. apple picking near me

    I truly love your blog.. Pleasant colors & theme. Did you create this web site yourself? Please reply back as Iím looking to create my own site and would like to find out where you got this from or exactly what the theme is called. Kudos!

    https://www.mundijuegos.com/messages/redirect.php?url=https://ocrvcenter.com

    June 17, 2021 at 10:54 | Report abuse | Reply
  9. bakeries near me

    An outstanding share! I have just forwarded this onto a friend who was doing a little homework on this. And he actually bought me lunch simply because I discovered it for him... lol. So let me reword this.... Thank YOU for the meal!! But yeah, thanks for spending time to talk about this matter here on your web page.

    https://www.singhui.com/uchome/link.php?url=https://www.masternearme.com/

    June 17, 2021 at 14:54 | Report abuse | Reply
  10. bowling alley near me

    Hi, I do think this is a great site. I stumbledupon it 😉 I may come back once again since i have book marked it. Money and freedom is the greatest way to change, may you be rich and continue to guide other people.

    http://220-server01.coldironcompanies.com/__media__/js/netsoltrademark.php?d=bestlocalnearme.com

    June 17, 2021 at 18:08 | Report abuse | Reply
  11. texas roadhouse near me

    After I initially commented I seem to have clicked on the -Notify me when new comments are added- checkbox and now whenever a comment is added I receive 4 emails with the same comment. Is there an easy method you can remove me from that service? Thanks!

    http://proxy.uriburner.com/fct/rdfdesc/usage.vsp?g=http://www.bjsnearme.com/

    June 17, 2021 at 18:20 | Report abuse | Reply
  12. sprint store near me

    Excellent article. I certainly appreciate this site. Keep writing!

    http://sawyersaving.com/__media__/js/netsoltrademark.php?d=bestservicenearme.com

    June 17, 2021 at 18:54 | Report abuse | Reply
  13. chicken wings near me

    Everything is very open with a really clear explanation of the challenges. It was truly informative. Your site is very useful. Thank you for sharing!

    http://bb3x.ru/go.php?http://masternearme.com/

    June 17, 2021 at 21:42 | Report abuse | Reply
  14. driving range near me

    https://www.bing.com/news/apiclick.aspx?ref=FexRss&aid=&url=https://www.bestshopnearme.com/&cc=be&setmkt=fr-be&setlang=fr-be

    June 17, 2021 at 22:46 | Report abuse | Reply
  15. batteries plus near me

    Iím impressed, I have to admit. Seldom do I come across a blog thatís both equally educative and entertaining, and let me tell you, you've hit the nail on the head. The problem is an issue that too few folks are speaking intelligently about. Now i'm very happy I found this in my search for something relating to this.

    http://www.btcuae.com/__media__/js/netsoltrademark.php?d=reviewnearme.com

    June 17, 2021 at 23:28 | Report abuse | Reply
  16. health food store near me

    http://iinet2.org/__media__/js/netsoltrademark.php?d=masternearme.com

    June 18, 2021 at 01:22 | Report abuse | Reply
  17. bbq near me

    http://www.nainews.com/__media__/js/netsoltrademark.php?d=bestshopnearme.com/

    June 18, 2021 at 04:07 | Report abuse | Reply
  18. keybank near me

    http://www.tbgweb.com/__media__/js/netsoltrademark.php?d=reviewnearme.com

    June 18, 2021 at 08:45 | Report abuse | Reply
  19. kinkos near me

    I could not refrain from commenting. Well written!

    http://www.bowlahat.com/__media__/js/netsoltrademark.php?d=www.wholesalenearme.com

    June 18, 2021 at 09:37 | Report abuse | Reply
  20. licensed general contractor

    This is a good tip especially to those fresh to the blogosphere. Short but very precise infoÖ Thank you for sharing this one. A must read article!

    http://finnp04d5.howeweb.com/5322973/not-known-factual-statements-about-generator-repair

    June 18, 2021 at 11:25 | Report abuse | Reply
  21. Camper Repair Places Near Me

    http://irwebcast.com/cgi-local/report/redirect.cgi?url=www.ocrvcenter.com/rv-fiberglass-repair-near-me/

    June 18, 2021 at 17:06 | Report abuse | Reply
  22. RV Repairs Near Me

    I used to be able to find good info from your articles.

    http://autocar.co.nz/Redirect.aspx?destination=http://ocrvcenter.com/rv-repair-shop-sun-valley-california/

    June 18, 2021 at 17:13 | Report abuse | Reply
  23. RV Repair Shops Near My Location

    Excellent web site you've got here.. Itís difficult to find good quality writing like yours nowadays. I really appreciate people like you! Take care!!

    http://slack-redir.net/link?url=http://ocrvexperts.com/rv-repair-shop-rialto-california/

    June 18, 2021 at 18:04 | Report abuse | Reply
  24. Nearest RV Repair

    https://herna.net/cgi/redir.cgi?https://www.ocrvcenter.com/rv-repair-shop-norco-california

    June 18, 2021 at 18:49 | Report abuse | Reply
  25. RV Repair Huntington Beach

    https://telecom.uu.ru/?a%5B%5D=<a+href=https://www.ocrvcenter.com/prostar-collision-repair-shop-near-me/

    June 18, 2021 at 23:29 | Report abuse | Reply
  26. Camper Repair Near Me

    Pretty! This was a really wonderful post. Thanks for providing this information.

    https://findit.timesleader.com/__media__/js/netsoltrademark.php?d=www.ocrv.info/rv-repair-shop-national-city-california/

    June 19, 2021 at 03:27 | Report abuse | Reply
  27. dentists near me

    http://nupp-legal-forms.org/__media__/js/netsoltrademark.php?d=nearmyspot.com

    June 19, 2021 at 06:00 | Report abuse | Reply
  28. RV Repair Orange County

    That is a great tip especially to those fresh to the blogosphere. Simple but very precise infoÖ Many thanks for sharing this one. A must read post!

    http://www.secure.duoservers.com/?lang=en&s_id=123179&rdomain=ocrvmotorsports.com/national-interstate-rv-collision-repair-shop-near-me&action=order&popup=1

    June 19, 2021 at 08:53 | Report abuse | Reply
  29. mega888sg.com

    Outstanding post however , I was wondering if you
    could write a litte more on this topic? I'd be very thankful if you could elaborate a little bit more.
    Many thanks!

    Here is my website; i aaa1188, mega888sg.com,

    June 19, 2021 at 13:44 | Report abuse | Reply
  30. 918kiss 2 slot game list

    For most recent news you have to pay a visit world-wide-web and on web I found this web site as a best
    web page for most up-to-date updates.

    my blog :: 918kiss 2 slot game list

    June 19, 2021 at 16:19 | Report abuse | Reply
  31. RV Repair Shops Near Me

    https://yellowpages.uticaod.com/__media__/js/netsoltrademark.php?d=ocrv.vip/international-truck-collision-repair-shop-near-me

    June 19, 2021 at 16:24 | Report abuse | Reply
  32. RV Repair Near My Location

    This website was... how do you say it? Relevant!! Finally I have found something that helped me. Cheers!

    https://www.bad.org.uk/for-the-public/patient-information-leaflets/androgenetic-alopecia/?showmore=1&returnlink=https://www.ocrv.info/rv-vinyl-wrap-repair-near-me

    June 19, 2021 at 16:52 | Report abuse | Reply
  33. Camper Repair Shops Near Me

    http://pt-br.paltalk.com/client/webapp/client/External.wmt?url=stfly.me/SGAHi0

    June 19, 2021 at 18:58 | Report abuse | Reply
  34. RV Repair California

    https://tools.folha.com.br/print?url=www.ocrvcenter.com/rv-repair-shop-cathedral-city-california

    June 19, 2021 at 20:53 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

Leave a Reply to international truck repair shop near me


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.