home
RSS
April 9th, 2012
12:01 AM ET

Mom's weight may be risk factor for autism

A mother's weight and diabetic condition may increase the risk of her unborn child developing a neurodevelopmental disorder, such as autism, according to a new study published in this week's journal Pediatrics.

Researchers with the UC Davis MIND Institute in California found that mothers-to-be who were obese were 67% more likely to have a child with autism as opposed to normal-weight mothers without diabetes or hypertension.

And a pregnant woman who is obese doubles her child's risk of having another developmental disorder (poor communication skills, lack of attention) compared to a child born to a mother at healthy weight.

The study included 1,004 mother-and-child pairs who were enrolled in the Childhood Autism Risks from Genetics and the Environment Study (CHARGE). Most of the families were from Northern California, with a small group living in Los Angeles.

The children were between 24 and 60 months old; 517 children had autism; 172 with other developmental disorders; and 315 were developing normally. The participants were enrolled between January 2003 and June 2010.

When it came to women with diabetes, researchers discovered they had more than two times the chance of having a child with developmental delays as opposed to those without diabetes.

"I was surprised at how strong the obesity effect was on new-born children and their cognitive development," said Dr. Irva Hertz-Picciotto, professor of Epidemiology and a researcher at the MIND Institute . "And we didn't just look at weight," she continued. "We looked at diabetes, and hypertension in mothers to see how those conditions affected their children. It was pretty significant."

The study also found that children with autism who were born to diabetic mothers had greater deficits in communication skills than the children with autism born to healthy mothers. Yet, many children who were not diagnosed with autism, but had diabetic mothers, also showed some signs of socialization problems as well as poor communication skills, compared to the non-autistic children of healthy women.

"Over a third of U.S. women in their childbearing years are obese and nearly one-tenth have gestational or type 2 diabetes during pregnancy," said Paula Krakowiak, a biostatician with the MIND Institute. "Our finding that these maternal conditions may be linked with neurodevelopment problems in children raises concerns and therefore may have serious public-health implications."

For more than a decade researchers have been looking for a genetic cause for autism. But new research suggests multiple genetic mutations make a child susceptible for the disorder.

In recent years, scientists have also been looking for environmental triggers that push these genetically susceptible children over the edge. As the search for these triggers continues, this research seems to suggest obesity may be one of those triggers in some cases.

Its authors say this is the first study to examine associations between neurodevelopmental disorders and maternal metabolic conditions. According to the Centers for Disease Control and Prevention, more than 60% of U.S. women of childbearing age are overweight, 34% are obese, and 16% have metabolic syndrome, a precursor to diabetes.

Nearly 9% of U.S.women of childbearing age are diabetic, and more than 1% of U.S. pregnancies are complicated because the mother has high blood pressure.

Obesity is a major risk factor for diabetes and hypertension and can increase insulin resistance and inflammation in the body. Study authors suggest in women with diabetes, unregulated sugar in the body can result in prolonged fetal exposure to high glucose levels which doctors say can affect brain development in unborn children.

"The fetus depends on the mother for nutrients," noted Dr. Hertz-Picciotto. "So at certain times in the fetal development if sugar levels or other nutrients are too high or too low, the imbalance can affect the fetus, especially when it comes to the brain."

But Hertz-Picciotto said there was good news from this study.

"The best thing about this is a lot of this can be modified," she said. "If you are thinking about getting pregnant, watch your weight and if you have diabetes have your doctor keep a close eye on you so you keep your glucose under control while you're carrying your baby."


soundoff (415 Responses)
  1. Zandra Retherford

    This web page can be a stroll-by means of for all of the data you needed about this and didn’t know who to ask. Glimpse here, and also you’ll undoubtedly uncover it.

    https://dreamproxies.com/free-proxies-and-discounts

    January 15, 2021 at 15:18 | Report abuse | Reply
  2. froleprotrem

    I loved as much as you'll receive carried out right here. The sketch is attractive, your authored subject matter stylish. nonetheless, you command get got an edginess over that you wish be delivering the following. unwell unquestionably come more formerly again as exactly the same nearly very often inside case you shield this hike.

    http://www.froleprotrem.com/

    January 18, 2021 at 16:00 | Report abuse | Reply
  3. Von Pomiecko

    Cheapest private proxies – costs only $0.15 for each proxy! Buy at this moment and find 50 discounted for the proxy bundle – DreamProxies.com

    https://dreamproxies.com/proxy-tag/100-usa-proxies-cheap-pricebuy-100-proxies-50-sale/

    January 18, 2021 at 23:40 | Report abuse | Reply
  4. froleprotrem

    Hello There. I found your weblog the usage of msn. This is a very smartly written article. I will make sure to bookmark it and return to learn more of your helpful info. Thank you for the post. I will definitely return.

    http://www.froleprotrem.com/

    January 21, 2021 at 21:37 | Report abuse | Reply
  5. Shalonda Kanipe

    I was planning on starting the guide with wordpress..

    https://ask-cloudkicker.tumblr.com/

    January 26, 2021 at 20:26 | Report abuse | Reply
  6. Dori Roat

    https://www.electricpercolatorcoffeepot.com/10-top-coffee-bloggers/

    January 28, 2021 at 22:26 | Report abuse | Reply
  7. frolep rotrem

    you have a great blog here! would you like to make some invite posts on my blog?

    http://www.froleprotrem.com/

    February 6, 2021 at 16:44 | Report abuse | Reply
  8. Europa-Road kombájn szállítás

    I’ve recently started a site, the info you offer on this website has helped me greatly. Thank you for all of your time & work.

    https://europa-road.eu/hu/kombajn-szallitas-mezogazdasagi-gep-szallitas.php

    February 9, 2021 at 04:26 | Report abuse | Reply
  9. Learn More

    Hey there, You've done a fantastic job. I’ll definitely digg it and personally recommend to my friends. I am confident they'll be benefited from this web site.

    http://www.dumpawaste.co.uk

    February 9, 2021 at 07:46 | Report abuse | Reply
  10. zortilonrel

    great points altogether, you just gained a new reader. What would you suggest in regards to your post that you made some days ago? Any positive?

    http://www.zortilonrel.com/

    February 16, 2021 at 08:55 | Report abuse | Reply
  11. zortilonrel

    Thanks for all your efforts that you have put in this. very interesting information.

    http://www.zortilonrel.com/

    February 16, 2021 at 09:44 | Report abuse | Reply
  12. Agen Judi Poker

    This is a topic which is near to my heart... Take care!
    Exactly where are your contact details though?

    February 24, 2021 at 08:46 | Report abuse | Reply
  13. Thanh Furness

    Excellent article. I am going through a few of these issues as well..

    https://proxyti.com/features

    February 26, 2021 at 21:53 | Report abuse | Reply
  14. Benjamin Tuel

    I’m amazed, I have to admit. Seldom do I come across a blog that’s both educative and amusing, and let me tell you, you have hit the nail on the head. The problem is something which not enough men and women are speaking intelligently about. Now i'm very happy I came across this during my hunt for something relating to this.

    https://proxyti.com/

    February 27, 2021 at 19:01 | Report abuse | Reply
  15. ClarkTauts

    emzoa dmyg3 44id

    February 28, 2021 at 14:14 | Report abuse | Reply
  16. ClarkTauts

    sawc9 6sijj 8le3

    March 1, 2021 at 14:48 | Report abuse | Reply
  17. Situs Judi Online

    It is the best time to make some plans for the future and it's time to be happy. I've read this post and if I could I desire to suggest you some interesting things or suggestions. Perhaps you can write next articles referring to this article. I wish to read more things about it!|

    https://ekuldime.net

    March 2, 2021 at 07:25 | Report abuse | Reply
  18. the best massage in london

    Say, you got a nice post. Keep writing.

    https://www.secrettantric.com/

    March 21, 2021 at 17:19 | Report abuse | Reply
  19. https://www.songmanhits.com

    I have never seen this view !

    https://images.google.com.do/url?q=https://www.songmanhits.com

    March 31, 2021 at 09:24 | Report abuse | Reply
  20. vardenafil 10 mg

    vardenafil sublingual under tongue https://vegavardenafil.com/ warnings for vardenafil

    April 3, 2021 at 19:41 | Report abuse | Reply
  21. alprostadil injection where to buy

    edex (alprostadil) https://alprostadildrugs.com/ video of transurethral alprostadil admimistering

    April 4, 2021 at 14:04 | Report abuse | Reply
  22. sildenafil pharmacy prices

    sildenafil brand name in canada https://eunicesildenafilcitrate.com/ where can i purchase sildenafil

    April 5, 2021 at 15:24 | Report abuse | Reply
  23. buy zithromax online cheap

    zithromax 250 mg price https://zithromaxes.com/ zithromax pfizer

    April 12, 2021 at 13:50 | Report abuse | Reply
  24. generic viagra cost walmart canada

    viagra canada https://canadaviagrastore.com/ viagra prices canada

    April 16, 2021 at 14:08 | Report abuse | Reply
  25. vardenafil vs tadalafil vs viagra which gives better erection?

    vardenafil prices https://vegavardenafil.com/ generic vardenafil 20mg india

    April 17, 2021 at 02:02 | Report abuse | Reply
  26. cialis on line purches canadian pharmacy

    cialis canadian pharmacy https://canadacialisstore.com/ do you need prescription for canadian prescription of cialis in usa

    April 21, 2021 at 03:36 | Report abuse | Reply
  27. injection suppository

    injectable drugs for erectile dysfunction https://alprostadildrugs.com/ ed medications injectable

    April 21, 2021 at 09:47 | Report abuse | Reply
1 2 3 4

Leave a Reply to Cynthia Zalenski


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.