Experimental treatment may help food allergies
March 5th, 2012
12:00 AM ET

Experimental treatment may help food allergies

Food allergies are tricky business. They're on the rise in the United States and no one knows why.

Some children are allergic to many foods, and it's impossible to know based on preventive testing whether someone will have a mild or severe reaction. And so far there's no cure.

Researchers at Johns Hopkins University and Duke University are working on a treatment that may one day allow kids with allergies to safely eat the foods that cause them life-threatening reactions. It's still in the early stages, but Dr. Robert Wood of Johns Hopkins, who has been on the forefront of food allergy research, estimates the treatment could be brought to the public within six to eight years.

In his new study, researchers explored a treatment for children with cow's milk allergies. The strategy is to desensitize the child by giving small amounts of the allergen (milk). Oral immunotherapy, swallowing small amounts of the allergen, has shown to be more effective than sublingual therapy, which involves putting even tinier quantities of milk under the person's tongue.

Wood and colleagues found promising results from this small experiment with 30 children ages 6 to 18. These kids were severely allergic to cow's milk. Wood presented the study, published in the Journal of Allergy and Clinical Immunology, at the 2012 Annual Meeting of the American Academy of Allergy, Asthma & Immunology this weekend.

The results suggested that children who went through a year of sublingual therapy followed by one to two years of oral immunotherapy were less likely to have significant allergic reactions when undergoing the oral immunotherapy. Still, it did not eliminate all symptoms.

This is particularly important, because about 20% of the kids that Wood and colleagues work with have significant reactions during the treatment that make the therapy unfeasible, Wood said.

Some participants have shown they can safely eat milk products up to a year after stopping the therapies, Wood said. But only one-third have longterm protection. Others need regular exposure to milk in order to maintain protection against allergic reactions.

"With milk that’s not too hard," Wood says, because one could "eat pizza a couple of times a week."

It's not known yet whether children respond better to this kind of treatment than adults, since there have been so few participants in this research. The big barrier to broadening the scope of the research is funding, Wood said.

This is the first time the sublingual therapy has been studied in terms of its benefit as a precursor to the oral immunotherapy, Wood said.

Other research has shown that immunotherapy techniques may similarly work for children with peanut allergies. But tree nuts may be harder to treat, Wood said, because tree-nut allergic individuals often have multiple kinds of nuts they can't eat.

Researchers are separately looking at a drug called omalizumab (Xolair), approved by the U.S. Food and Drug Administration for the treatment of severe asthma, to see if it could help people with food allergies, too.

Do not try the immunotherapy technique at home; these experiments are conducted under medical supervision.

soundoff (95 Responses)
  1. FhsnZisse

    female viagra pills australia boots viagra online young people viagra

    December 15, 2020 at 06:49 | Report abuse | Reply
  2. Orville Elis

    Mecanizados en general, para piezas únicas series en nuestras instalaciones. Fabricación de máquinas especiales y equipos de control para la industria del automóvil. Si estás buscando las mejores empresas de mecanizados en Valencia, con gusto te podemos ayudar.


    December 20, 2020 at 11:47 | Report abuse | Reply
  3. FgvdZisse

    best drugstore eyebrow pencil best drugstore primer best drugstore eyebrow pencil

    January 10, 2021 at 03:50 | Report abuse | Reply
  4. JtmfEncox

    ed meds online pharmacy canadian drug pharmacy

    January 10, 2021 at 16:56 | Report abuse | Reply
  5. LokuEncox

    online pharmacy reviews ed ed meds

    January 10, 2021 at 18:37 | Report abuse | Reply
  6. KhthMile

    best drugstore face moisturizer best drugstore face moisturizer pharma

    January 11, 2021 at 00:45 | Report abuse | Reply
  7. zortilo nrel

    Just desire to say your article is as amazing. The clarity in your post is simply nice and i can assume you're an expert on this subject. Well with your permission allow me to grab your RSS feed to keep up to date with forthcoming post. Thanks a million and please continue the enjoyable work.


    January 11, 2021 at 02:38 | Report abuse | Reply
  8. FwsxEncox

    the pharmacy best drugstore face wash pharmacy rx world

    January 11, 2021 at 08:04 | Report abuse | Reply
  9. Rosalba Balckwell

    Hiya, I am really glad I’ve found this information. Today bloggers publish just about gossip and internet stuff and this is actually irritating. A good website with exciting content, that’s what I need. Thank you for making this website, and I’ll be visiting again. Do you do newsletters? I Cant find it.


    January 12, 2021 at 01:56 | Report abuse | Reply
  10. NllpZisse

    drugstore near me 24 hour pharmacy rx express pharmacy

    January 12, 2021 at 10:31 | Report abuse | Reply
  11. FgnhZisse

    discount viagra buy viagra in spain viagra trial voucher viagra 100mg viagra australia free nitric oxide and viagra where to buy viagra in toronto viagra pills for sale is posssible buy viagra no prescription at walgrees? walmart pharmacy online viagra viagra site:au but viagra with no prescription viagra without presciption generic viagra suppliers viagra

    January 14, 2021 at 07:27 | Report abuse | Reply
  12. zortilo nrel

    Just wish to say your article is as astonishing. The clearness in your post is just spectacular and i could assume you're an expert on this subject. Well with your permission allow me to grab your feed to keep up to date with forthcoming post. Thanks a million and please continue the rewarding work.


    January 14, 2021 at 21:22 | Report abuse | Reply
  13. KlioMile

    cheap pfizer viagra online order viagra with pay pal newsletter viagra natural viagra alternatives medical cvs viagra viagra prices viagra gel uk can i get walk in and buy viagra at wal mart today purchase viagra in australia viagra dosage instructions viagra samples free online viagra canada customs viagra/cialis black and gold 800 viagra for sale malaysia buying viagra by paypal

    January 16, 2021 at 00:18 | Report abuse | Reply
  14. NlbxZisse

    viagra cheap overnight shippimg generic viagra mastercard buy viagra and prescription drugs viagra online viagra vanessa hudgens oline generic viagra sildenafil citrate generic viagra soft tabs cheap prices for viagra purchase viagra without prescription viagra trial pack best price for generic viagra il viagra in uk viagra george south africa canadian pharmacy viagra & cialis viagra pills 90

    January 16, 2021 at 13:15 | Report abuse | Reply
  15. FbdhZisse

    cialis without persciction how to buy cialis online from canada cialis without prescripe http://21cialismen.com/ – cialis trial coupon ’

    January 19, 2021 at 08:19 | Report abuse | Reply
  16. JbdcEncox

    viagra online pharmacy australia chdap viagra viagra buy http://llviabest.com/ – viagra uk ’

    January 20, 2021 at 11:35 | Report abuse | Reply
  17. LcxEncox

    viagra online without perscription viagra pills in ilkeston over counter viagra canada http://genqpviag.com/ – health care products,viagra toronto ’

    January 20, 2021 at 13:10 | Report abuse | Reply
  18. KbctMile

    new cialis commercial 2010 buy cialis by paypal cialis for sale nz http://mycialedst.com/ – cialis black ’

    January 20, 2021 at 23:27 | Report abuse | Reply
  19. NlbxZisse

    generic cialis tadalafil 20mg online cialis reviews cialis dosage recommend http://cialijomen.com/ – cialis in manitoba ’

    January 21, 2021 at 14:00 | Report abuse | Reply
  20. AqbvEncox

    4 pack viagra buy viagra with paypal uk buying viagra online in australia http://acialaarx.com/ – generic viagra on line ’

    January 21, 2021 at 15:38 | Report abuse | Reply
1 2

Leave a Reply to movierulz3


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.