home
RSS
Common chemical linked to Parkinson's
November 14th, 2011
06:45 PM ET

Common chemical linked to Parkinson's

Exposure to a man-made chemical known as trichloroethylene, or TCE, is associated with a sixfold increased risk of developing Parkinson's disease, according to a new study published Monday in the Annals of Neurology. TCE is a common organic contaminant that pollutes groundwater, soil, and air.

The study also found that exposure to another man-made chemical similar to TCE, known as perchloroethylene or tetrachloroethylene, or PERC, is associated with a tenfold increased risk of Parkinson's. Both chemicals are found in metal degreasers, metal cleaners, paint, spot removers, and carpet-cleaning fluids.

"The fact that we were able to find a six-to-tenfold increased risk in exposure I think is very meaningful," says Dr. Samuel M. Goldman, an associate professor of clinical research at The Parkinson's Institute and the lead author of the study.

Chemicals and solvents like TCE have been anecdotally linked to Parkinson's disease before but according to Goldman, no epidemiologic study has been done to verify the relationship until now.

To conduct the study, Goldman and his team identified six specific solvents previously suspected to be related to the development of Parkinson's, two of which were TCE and PERC. They then reached out to 99 all-male pairs of twins, each composed of one twin with Parkinson's and one without. The twins were all male because they were part of the National Academy of Sciences/National Research Council World War II Veteran Twins Registry that was founded in the 1960s using military records.

Goldman and his team interviewed the twins using detailed job-specific questionnaires to gauge the likelihood of each person being exposed to the predetermined solvents.

"We designed these extremely detailed interviews so that we didn't have to rely on the memory or the knowledge of the respondent," explains Goldman.

For example, if one of the study participants said he used to work as an aircraft mechanic in the 1950s, Goldman and his team would question the participant about the different duties or machinery the job involved.

"We know the geographic locations where [each participant] worked, the decade, and what they did so we can say, 'OK – we know that with someone who worked in the 1950s, in a plant with air plane engines, and they were working with the degreasing process, there is a high likelihood that person was exposed to TCE.'"

By working with twins, Goldman and his team were able to account for genetic and lifestyle factors and focus on the job differences between each brother, one of whom had Parkinson's. They found that exposure to TCE, PERC, and to a lesser extent another chemical known as carbon tetrachloride, were all associated with an increased risk of the neurodegenerative disease.

Goldman says that single finding could have major public health implications given how ubiquitous these chemicals, particularly TCE, are in the environment.

"These results need to be replicated," says Goldman. "Even though we have this single epidemiologic study, it's something that needs to be studied quickly."

That sense of urgency is reinforced by the Environmental Protection Agency's recent decision to classify TCE as a known human carcinogen. In an email to CNN, a spokesman for the EPA says the agency believes there is no "acceptable" level of the chemical in groundwater because of its designation as a carcinogen. However, the agency has set a maximum standard of five parts per billion (ppb) to help measure and enforce the amount of TCE in water supplies around the country.

"Clean water is critical to the health and prosperity of every American community and a fundamental concern to every American family," the EPA spokesman wrote to CNN.

The findings in Goldman's study support an emerging line of thought among Parkinson's researchers that the disease is caused by a combination of genetic and environmental factors.

"In Parkinson's disease, research has been pointing in the direction supporting the notion that genetics loads the gun, and the environment pulls the trigger," says Dr. Michael S. Okun, medical director of the National Parkinson Foundation.

"This may make the investigation of pesticides, toxins, and trauma very important to understanding what leads to this disease."

Goldman agrees and says more research needs to be done to identify potential environmental triggers like TCE.


« Previous entry
soundoff (1,370 Responses)
  1. Leigh Pallansch

    http://images.google.be/url?q=http://jasperj69l7.blogozz.com/4047132/the-definitive-guide-to-truck-repair-shop-near-me

    June 11, 2021 at 10:56 | Report abuse | Reply
  2. Oleta Londo

    https://tieba.baidu.com/mo/q/checkurl?url=https://donovane60s1.canariblogs.com/value-of-appointed-day-successful-day-in-restructuring-16623501

    June 11, 2021 at 12:03 | Report abuse | Reply
  3. Elin Catanese

    https://www.treasury.gov/cgi-bin/redirect.cgi/?https://www.griffing69k7.ambien-blog.com/5572607/the-5-second-trick-for-rv-awning-repair-shop-near-me

    June 11, 2021 at 12:03 | Report abuse | Reply
  4. vtv trực tuyến vtv1

    Thẳng Bóng Đá Việt Nam Vs Lebanon. Coi Truc Tiep Bong Da. Futsal Việt Nambet168Trên băng ghế giảng dạy, Lebanon đã bửa nhiệm Ramiro Lopez cách đây 3 tuần. Nhà cầm quân người Tây Ban Nha nhà yếu ớt làm việc tại Ý và từng có thời gian làm việc tại Kuwait.|Và NHM bóng đá Việt Nam đang được chờ Minh Trí cùng đồng đội hóa giải đối thủ để tạo lợi thế cho trận lượt về tại đây hai ngày. Chelsea đã cần trải qua 8 phút bù giờ nghẹt thở bảo vệ thắng lợi.

    https://bongdatv.vn/detail/truc-tuyen-htv7-vien-ngoc-rong-4-104349.html

    June 11, 2021 at 12:58 | Report abuse | Reply
  5. for sale near me

    guns

    June 11, 2021 at 17:31 | Report abuse | Reply
  6. does rv insurance cover roof leaks

    https://www.membership.newcastlejets.com.au/analytics/outbound?url=http://ocrvcenter.org/

    June 11, 2021 at 17:31 | Report abuse | Reply
  7. https://www.adultchatsex.com/kati3kat/

    I wwas wondering if you ever considered changing the layout of your website?

    Itss very well written; I love what youve got to say.
    But maybe you could a little more in the way off content so people could connect with it
    better. Youve got an awful loot of text for only having 1 or
    2 pictures. Maybe you could space it out better?

    Feel fre to sirf to mmy page: https://www.adultchatsex.com/kati3kat/

    June 11, 2021 at 19:01 | Report abuse | Reply
  8. RV Refrigerator California

    https://www.cracking.com.ar/redir/redir.php?URL=https://carsonrvexperience.com

    June 11, 2021 at 22:50 | Report abuse | Reply
  9. Business Van Repair Shop

    Hi, I do think your site could possibly be having browser compatibility issues. Whenever I look at your blog in Safari, it looks fine however, when opening in I.E., it's got some overlapping issues. I simply wanted to provide you with a quick heads up! Aside from that, excellent website!

    http://apollo.danirvinrather.com/__media__/js/netsoltrademark.php?d=www.fleetservicesorangecounty.com/

    June 11, 2021 at 22:51 | Report abuse | Reply
  10. Sprinter 2500 Front Glass Repair

    http://annpirruccello.com/__media__/js/netsoltrademark.php?d=commercialrepairshop.com/

    June 11, 2021 at 23:05 | Report abuse | Reply
  11. Motorhome Repair

    https://cross-a.net/go_out.php?url=https://campervanrepairshop.com/

    June 12, 2021 at 00:29 | Report abuse | Reply
  12. rv slide repair

    https://www.bungersurf.com/Redirect.aspx?destination=http://ocrvmotorsports.us

    June 12, 2021 at 00:59 | Report abuse | Reply
  13. raleigh collision repair

    Wow this blog is very nice!

    https://pr9websites.com/auto-body-repairs-work-for-budgets/

    June 12, 2021 at 01:32 | Report abuse | Reply
  14. after school program in gambrills md

    such a great information for blogger i am a professional blogger thanks

    https://emunahhealth.com/blog/2018/05/03/how-sitting-can-affect-health

    June 12, 2021 at 02:57 | Report abuse | Reply
  15. after school program near gambrills md

    I'm not sure where you are getting your information, but great topic.

    https://scientific-programs.science/wiki/Vital_Causes_Your_Child_Must_Be_Enrolled_in_an_Right_after_College_Method

    June 12, 2021 at 06:12 | Report abuse | Reply
  16. motorhome remodeling companies

    http://jernia.com/__media__/js/netsoltrademark.php?d=www.ocrv.tv/

    June 12, 2021 at 08:35 | Report abuse | Reply
  17. RV Upgrades Riverside

    http://www.teachingengine.net/__media__/js/netsoltrademark.php?d=ocrvmotorsports.biz/

    June 12, 2021 at 10:05 | Report abuse | Reply
  18. Conversion Van Repair Shop

    Greetings! Very helpful advice in this particular article! It is the little changes which will make the most significant changes. Many thanks for sharing!

    http://kin.vaccineh5n1.info/__media__/js/netsoltrademark.php?d=sprintervanrepair.com

    June 12, 2021 at 10:05 | Report abuse | Reply
  19. EncoxGtv

    do canadian pharmacies verify prescriptions onlinecanadianpharmacy canadadrugpharmacy com

    June 12, 2021 at 10:15 | Report abuse | Reply
  20. RV Roof Repair Service

    Hello there! I simply wish to give you a huge thumbs up for the great information you have here on this post. I am coming back to your web site for more soon.

    http://www.lnbrb.us/__media__/js/netsoltrademark.php?d=campervanrepairshop.com

    June 12, 2021 at 10:28 | Report abuse | Reply
  21. Sprinter 2500 Front Glass Repair

    https://dta365.com/dt/uchome/link.php?url=https://fleetautorepairshop.com

    June 12, 2021 at 11:05 | Report abuse | Reply
  22. Free Jennica Lynn

    Its not my first time to pay a quick visit this web site, i am browsing this web page dailoly aand obtain fastidious
    data from here every day.

    Review my site – Free Jennica Lynn

    June 12, 2021 at 11:16 | Report abuse | Reply
  23. social-store.net

    It's very trouble-free to find out any matter on net as compared to books, as I found this paragraph at this site.

    June 12, 2021 at 14:43 | Report abuse | Reply
  24. cheap hotels near me

    I'd like to thank you for the efforts you have put in writing this website. I'm hoping to view the same high-grade blog posts by you later on as well. In fact, your creative writing abilities has inspired me to get my own, personal blog now 😉

    https://europe.google.com/url?rct=j&sa=t&url=https://bjsnearme.com/motorhome-shades-repair-near-me

    June 12, 2021 at 17:34 | Report abuse | Reply
  25. suntrust near me

    I seriously love your website.. Pleasant colors & theme. Did you make this website yourself? Please reply back as Iím planning to create my own blog and would like to find out where you got this from or just what the theme is named. Thank you!

    http://www.sydneyevan.net/__media__/js/netsoltrademark.php?d=bulknearme.com/

    June 12, 2021 at 18:35 | Report abuse | Reply
  26. Chance

    Thanks for the marvelous posting! I really enjoyed reading it, you may be a
    great author.I will be sure to bookmark your blog and will eventually come back down the road.
    I want to encourage you to continue your great writing, have a nice
    evening!

    my blog: اجاره خودرو, Chance,

    June 12, 2021 at 18:52 | Report abuse | Reply
  27. Https://Sites.Google.Com/View/Live-Sex-Cams-Chaturbate/Home

    Have you ever considered about including a little bit
    more than just your articles? I mean, what you say
    is valuable and everything. Nevertheless imagine iif yyou added some great
    pictures or videos to give your poists more, "pop"! Yoour content is exfellent but wth pics and viddeo clips,
    this blog could certainly be one of the most beneficial in its field.
    Terrific blog!

    my web site – https://Sites.Google.Com/View/Live-Sex-Cams-Chaturbate/Home

    June 12, 2021 at 18:57 | Report abuse | Reply
  28. rapid results covid testing near me

    http://www.hoagsummerfestival.com/__media__/js/netsoltrademark.php?d=hootnholler.net/

    June 12, 2021 at 21:08 | Report abuse | Reply
  29. verizon wireless near me

    http://www.ricefamily.com/__media__/js/netsoltrademark.php?d=quotenearme.com/

    June 12, 2021 at 22:20 | Report abuse | Reply
  30. urologist near me

    http://weekly.chosun.com/protect_weekly/redirect.asp?url=https://bulknearme.com/

    June 12, 2021 at 22:41 | Report abuse | Reply
  31. police.bet

    This is the right webpage for anyone who wants to find out about this topic.
    You understand a whole lot its almost hard to argue with
    you (not that I personally would want to…HaHa).
    You certainly put a brand new spin on a topic which has been written about for ages.
    Excellent stuff, just excellent!

    June 12, 2021 at 23:30 | Report abuse | Reply
  32. https://Www.adultchatsex.Com/annabel-redd/

    Hi too every body, it's my first go too see of
    this website; this blog contains remarkable and realoly excellent data for readers.

    Visit my homepage – https://Www.adultchatsex.Com/annabel-redd/

    June 13, 2021 at 04:45 | Report abuse | Reply
  33. toyota dealers near me

    http://sunhun.com/link.php?url=https://nearmyspot.com

    June 13, 2021 at 08:23 | Report abuse | Reply
  34. dollar store near me

    http://adicg.com/__media__/js/netsoltrademark.php?d=bestservicenearme.com

    June 13, 2021 at 09:38 | Report abuse | Reply
  35. brewery near me

    Way cool! Some very valid points! I appreciate you penning this post plus the rest of the website is really good.

    http://findrecipe.com/__media__/js/netsoltrademark.php?d=www.bestshopnearme.com

    June 13, 2021 at 11:18 | Report abuse | Reply
  36. pizza near me

    http://www.hawkspur.com/__media__/js/netsoltrademark.php?d=bestshopnearme.com/

    June 13, 2021 at 11:50 | Report abuse | Reply
  37. EncoxAni

    pharmacy on line canada prescription cost comparison canada-pharmacy-365

    June 13, 2021 at 14:08 | Report abuse | Reply
  38. Https://Www.Adultchatsex.Com/Littlebuffbabe/

    When I initially commented I clicked thee "Notify me when new comments are added" checkbox and now
    each time a comment is added I gett several e-mails with the same comment.

    Is there any wayy you can remove me from that service?
    Cheers!

    Here is my web site – https://Www.Adultchatsex.Com/Littlebuffbabe/

    June 14, 2021 at 01:25 | Report abuse | Reply
  39. Emely

    Fantastic website. Lots of useful information here.
    I am sending it too some friends ans aldo sharing in delicious.
    And of course, thank you iin your effort!

    Also visit my blog post :: Dulceyjohn (Emely)

    June 14, 2021 at 03:45 | Report abuse | Reply
  40. Anabel054 performance

    I enjoy readding through an article that
    will make people think. Also, thank you for permitting me to comment!

    Also visit my web blog – Anabel054 performance

    June 14, 2021 at 05:05 | Report abuse | Reply
  41. urologist near me

    http://hzql.ziwoyou.net/m2c/2/s_date0.jsp?tree_id=0&sdate=2019-11-01&url=http://www.cateringbusinessplans.com/

    June 14, 2021 at 08:52 | Report abuse | Reply
  42. hospital near me

    Everything is very open with a very clear clarification of the challenges. It was really informative. Your website is useful. Thanks for sharing!

    https://sc.sie.gov.hk/TuniS/internetmarketingidaho.com

    June 14, 2021 at 09:05 | Report abuse | Reply
  43. truyen hinh online vtv3

    Kết Trái Futsal Việt Nam Vs Lebanonlich bong da giao huu hom nayTheo thể thức thi đấu, đội thắng ở cặp đấu này sẽ giành tấm vé đến Lithuania trong ngày hội bóng đá lớn nhất thế giới mang đến futsal. Tuyển futsal Việt Nam bước vào trận play-off lượt đi tranh vé dự play-off World Cup 2021 với sự tự tin. Tuy vậy, HLV Phạm Minh Giang bày tỏ, toàn đội ko ngán Lebanon song sẽ tìm cách để khắc chế sức mạnh của đối thủ bởi bên trên băng ghế huấn luyện là nhà cầm quân Ramiro Lopez, người từng dẫn dắt futsal Tây Ban Nha.|Dựa vào lịch thi đấu, bạn có thể chuẩn bị xếp việc làm

    https://virandoamor.com/detail/fpt-truc-tiep-vtv-6-129538.html

    June 14, 2021 at 09:27 | Report abuse | Reply
  44. Kaylee

    Greetings from Los angeles! I'm bored at work so I decided to check out your
    site on my iphone during lunch break. I enjoy the info you present
    here and can't wait to take a look when I get home. I'm shocked at how fast your blog
    loaded on my phone .. I'm not even using
    WIFI, just 3G .. Anyhow, very good blog!

    my web site ... حال کامل; Kaylee,

    June 14, 2021 at 10:02 | Report abuse | Reply
  45. minute clinic near me

    You ought to take part in a contest for one of the finest sites on the internet. I am going to highly recommend this site!

    http://b.grabo.bg/special/dealbox-492×73/?rnd=2019121711&affid=19825&deal=199235&cityid=1&city=Sofia&click_url=eyedoctorphoenixaz.com

    June 14, 2021 at 10:05 | Report abuse | Reply
  46. subaru dealer near me

    Hey there! I simply wish to offer you a big thumbs up for your great information you've got right here on this post. I'll be coming back to your website for more soon.

    http://blog.so-net.ne.jp/_pages/mobile/step/index?u=www.makemoneymommas.com/

    June 14, 2021 at 11:03 | Report abuse | Reply
  47. towing near me

    https://2ch-ranking.net/redirect.php?url=https://www.lacapillacantina.com

    June 14, 2021 at 11:17 | Report abuse | Reply
  48. teriyaki near me

    http://go.20script.ir/index.php?url=https://autopartsservicenearme.com

    June 14, 2021 at 14:31 | Report abuse | Reply
  49. Pearline

    If you desire to increase your familiarity simply
    keep visiting this website and be updated with the latest news update posted here.

    Here is my webpage :: معتبرترین سایت شرطبندی (Pearline)

    June 14, 2021 at 14:37 | Report abuse | Reply
  50. auto parts store near me

    http://234ww.com/__media__/js/netsoltrademark.php?d=https://ocrv.me

    June 14, 2021 at 14:41 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

« Previous entry
Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.