home
RSS
Common chemical linked to Parkinson's
November 14th, 2011
06:45 PM ET

Common chemical linked to Parkinson's

Exposure to a man-made chemical known as trichloroethylene, or TCE, is associated with a sixfold increased risk of developing Parkinson's disease, according to a new study published Monday in the Annals of Neurology. TCE is a common organic contaminant that pollutes groundwater, soil, and air.

The study also found that exposure to another man-made chemical similar to TCE, known as perchloroethylene or tetrachloroethylene, or PERC, is associated with a tenfold increased risk of Parkinson's. Both chemicals are found in metal degreasers, metal cleaners, paint, spot removers, and carpet-cleaning fluids.

"The fact that we were able to find a six-to-tenfold increased risk in exposure I think is very meaningful," says Dr. Samuel M. Goldman, an associate professor of clinical research at The Parkinson's Institute and the lead author of the study.

Chemicals and solvents like TCE have been anecdotally linked to Parkinson's disease before but according to Goldman, no epidemiologic study has been done to verify the relationship until now.

To conduct the study, Goldman and his team identified six specific solvents previously suspected to be related to the development of Parkinson's, two of which were TCE and PERC. They then reached out to 99 all-male pairs of twins, each composed of one twin with Parkinson's and one without. The twins were all male because they were part of the National Academy of Sciences/National Research Council World War II Veteran Twins Registry that was founded in the 1960s using military records.

Goldman and his team interviewed the twins using detailed job-specific questionnaires to gauge the likelihood of each person being exposed to the predetermined solvents.

"We designed these extremely detailed interviews so that we didn't have to rely on the memory or the knowledge of the respondent," explains Goldman.

For example, if one of the study participants said he used to work as an aircraft mechanic in the 1950s, Goldman and his team would question the participant about the different duties or machinery the job involved.

"We know the geographic locations where [each participant] worked, the decade, and what they did so we can say, 'OK – we know that with someone who worked in the 1950s, in a plant with air plane engines, and they were working with the degreasing process, there is a high likelihood that person was exposed to TCE.'"

By working with twins, Goldman and his team were able to account for genetic and lifestyle factors and focus on the job differences between each brother, one of whom had Parkinson's. They found that exposure to TCE, PERC, and to a lesser extent another chemical known as carbon tetrachloride, were all associated with an increased risk of the neurodegenerative disease.

Goldman says that single finding could have major public health implications given how ubiquitous these chemicals, particularly TCE, are in the environment.

"These results need to be replicated," says Goldman. "Even though we have this single epidemiologic study, it's something that needs to be studied quickly."

That sense of urgency is reinforced by the Environmental Protection Agency's recent decision to classify TCE as a known human carcinogen. In an email to CNN, a spokesman for the EPA says the agency believes there is no "acceptable" level of the chemical in groundwater because of its designation as a carcinogen. However, the agency has set a maximum standard of five parts per billion (ppb) to help measure and enforce the amount of TCE in water supplies around the country.

"Clean water is critical to the health and prosperity of every American community and a fundamental concern to every American family," the EPA spokesman wrote to CNN.

The findings in Goldman's study support an emerging line of thought among Parkinson's researchers that the disease is caused by a combination of genetic and environmental factors.

"In Parkinson's disease, research has been pointing in the direction supporting the notion that genetics loads the gun, and the environment pulls the trigger," says Dr. Michael S. Okun, medical director of the National Parkinson Foundation.

"This may make the investigation of pesticides, toxins, and trauma very important to understanding what leads to this disease."

Goldman agrees and says more research needs to be done to identify potential environmental triggers like TCE.


« Previous entry
soundoff (1,370 Responses)
  1. Chevy Van Repair Panels

    You are so interesting! I don't think I have read through a single thing like that before. So great to find another person with unique thoughts on this topic. Really.. many thanks for starting this up. This site is something that is required on the internet, someone with a little originality!

    https://www.quanlaoda.com/links.php?url=https://revol-presto.jp/presto-chatan/customers-voice/お客様の声01-2/attachment/chatan_questionnaires-10-2

    May 16, 2021 at 12:24 | Report abuse | Reply
  2. Alternator Mercedes Sprinter 2016 Repair

    /

    May 16, 2021 at 12:27 | Report abuse | Reply
  3. Sprinter Van Inside Computer Repair Shop

    After going over a number of the blog articles on your web page, I seriously appreciate your technique of blogging. I bookmarked it to my bookmark website list and will be checking back in the near future. Please visit my web site as well and tell me how you feel.

    http://neoromance.info/link/rank.cgi?mode=link&id=26&url=http://sprintervanrepairshop.com/tow-truck-repair-shop-near-me

    May 16, 2021 at 17:16 | Report abuse | Reply
  4. Independent Maserati Service Near Me

    Greetings! Very helpful advice within this article! It's the little changes that will make the most important changes. Many thanks for sharing!

    https://webpoint.usfieldhockey.com/wp15/Email/CT.wp?cx=xa_mzx__x__x__tyx__ccdrvi&pz=zqppccfccvx__i&tgt=http://www.club-maserati.com

    May 16, 2021 at 18:19 | Report abuse | Reply
  5. Repair My 2006 Dodge Sprinter 3500 Rv

    This blog was... how do I say it? Relevant!! Finally I have found something which helped me. Cheers!

    https://www.htcdev.com/?URL=www.commercialvanrepairshop.com/testimonials/

    May 16, 2021 at 18:33 | Report abuse | Reply
  6. Repair 2005 Sprinter Ecm

    http://ace-ace.co.jp/cgi-bin/ys4/rank.cgi?mode=link&id=26651&url=https://fleetautorepairshop.com/sprinter-van-upgrades-shop-near-me

    May 16, 2021 at 21:38 | Report abuse | Reply
  7. 2005 Dodge Sprinter 2500 A/C Heater Controls Repair

    https://www.gvomail.com/redir.php?k=1560a19819b8f93348a7bc7fc28d0168&url=https://commercialrepairshop.com/gmc-luxury-van-repair-shop-near-me

    May 16, 2021 at 21:49 | Report abuse | Reply
  8. Art Van Repair

    https://www.sprinter-forum.de/clickcounter?url=http://fleettruckrepairshop.com/ram-high-top-van-repair-shop-near-me/&kategorie=Werbung&linkbereich=Header

    May 17, 2021 at 04:24 | Report abuse | Reply
  9. Dodge Sprinter Repair Shop

    I must thank you for the efforts you've put in penning this website. I am hoping to see the same high-grade blog posts from you later on as well. In fact, your creative writing abilities has motivated me to get my own website now 😉

    https://www.cropscience.bayer.ca/?setlanguage=en&returnUrl=https://fleetservicerepairshop.com/uhaul-truck-repair-shop-near-me

    May 17, 2021 at 05:14 | Report abuse | Reply
  10. Dodge Sprinter Auto Repair

    Everyone loves it whenever people come together and share opinions. Great blog, continue the good work!

    http://www.singhui.com/uchome/link.php?url=https://www.fleettruckrepairshop.com/maintenance-shop-near-me

    May 17, 2021 at 06:23 | Report abuse | Reply
  11. Van Auto Repair

    Hello! I just want to offer you a huge thumbs up for your great information you've got right here on this post. I will be coming back to your web site for more soon.

    http://www.kichink.com/home/issafari?uri=http://www.commercialvanrepairshop.com/mercedes-cargo-van-repair-shop-near-me/

    May 17, 2021 at 07:45 | Report abuse | Reply
  12. FmrfEncox

    how to purchase cialis in canada http://cialisee.com/ – generi cialis cialis on line

    May 17, 2021 at 08:18 | Report abuse | Reply
  13. Authorized Mercedes Sprinter Service Centers Near Me

    http://old.evraz.com/bitrix/redirect.php?event1=news_out&event2=/upload/iblock/137/EVRAZ_ZSMK_Krajowa+ocena+techniczna+ITB-КОТ-2017_0052.pdf&event3=EVRAZ_ZSMK_Krajowa+ocena+techniczna+ITB-КОТ-2017_0052.pdf&goto=https://boxtruckrepairshop.com/rv-maintenance-shop-near-me/

    May 17, 2021 at 10:03 | Report abuse | Reply
  14. 歡迎光臨

    Normally I don't read post on blogs, however I would like to say that this write-up very pressured me to check out and do it!
    Your writing style has been surprised me. Thank you, quite great article.

    May 17, 2021 at 10:58 | Report abuse | Reply
  15. Van Wheelchair Lift Repair

    Saved as a favorite, I love your blog!

    https://login.talend.com/logout.php?redirectUrl=https://fleetvehiclerepairshop.com/pleasure-way-van-repair-shop-near-me/

    May 17, 2021 at 11:09 | Report abuse | Reply
  16. 2008 Maserati Granturismo For Sale

    http://www.im-harz.com/counter/counter.php?url=http://www.maseratiforum.net/

    May 17, 2021 at 12:34 | Report abuse | Reply
  17. toilet repair near me

    An outstanding share! I have just forwarded this onto a friend who had been conducting a little homework on this. And he actually ordered me lunch because I discovered it for him... lol. So allow me to reword this.... Thank YOU for the meal!! But yeah, thanx for spending the time to discuss this subject here on your web page.

    http://p-hero.com/hsee/rank.cgi?mode=link&id=88&url=https://12rex.com/the-basque-problem/p0003963/

    May 17, 2021 at 17:26 | Report abuse | Reply
  18. rv orange county

    http://dyna.boe.ttct.edu.tw/netlink/hits.php?id=438&url=https://ocrvcenter.com

    May 18, 2021 at 07:01 | Report abuse | Reply
  19. windshield repair orange county

    http://www.euroweb.com/aspmoduli/statistiche/vaiurl.asp?url=https://ocrvcenter.com

    May 18, 2021 at 08:37 | Report abuse | Reply
  20. 7호선석남역개통

    It's in reality a great and useful piece of information. I am happy that you simply shared
    this useful info with us. Please stay us informed like
    this. Thank you for sharing.

    May 18, 2021 at 09:38 | Report abuse | Reply
  21. How Much Does A Maserati Car Cost

    This is a topic which is near to my heart... Many thanks! Where are your contact details though?

    https://www.rc-webdesign-und-internet.de/besucherzaehler-counter/dlcount.php?id=Ballak_Kai-Erik&url=https://maseratis.net

    May 18, 2021 at 15:22 | Report abuse | Reply
  22. Family Dental Clinic

    Good post! We will be linking to this great content on our website. Keep up the good writing.

    https://domaindirectory.com/servicepage/?domain=getdentalimplantsnearme.com

    May 18, 2021 at 15:33 | Report abuse | Reply
  23. online meditation coach

    I was able to find good information from your blog posts.

    http://www.zhhsw.com/home/link.php?url=https://menmastermind.com/

    May 18, 2021 at 19:51 | Report abuse | Reply
  24. mindset coach

    http://webstolica.ru/go.php?link=menmastermind.com

    May 18, 2021 at 20:33 | Report abuse | Reply
  25. Maserati Reviews

    http://letronc-m.com/redirector?url=https://club-maserati.com/

    May 18, 2021 at 23:08 | Report abuse | Reply
  26. Roofing Supply Company Near Me

    You ought to be a part of a contest for one of the best sites on the web. I will highly recommend this site!

    https://ad.atdmt.com/c/img?h=https://sanmarinoroof.com/

    May 19, 2021 at 00:22 | Report abuse | Reply
  27. Best Pediatric Optometrist Near Me

    I’m impressed, I must say. Seldom do I encounter a blog that’s both educative and interesting, and let me tell you, you have hit the nail on the head. The issue is something not enough people are speaking intelligently about. I am very happy that I came across this in my search for something relating to this.

    https://fotobug.net/home/link.php?url=https://eyedoctorphoenixaz.com

    May 19, 2021 at 01:14 | Report abuse | Reply
  28. Eyeglasses Exam Near Me

    http://chaosns.com/link.php?url=https://optometristphoenixaz.com

    May 19, 2021 at 01:30 | Report abuse | Reply
  29. Eye Exam Near Me

    http://p4trc.emv2.com/DTS?url=https://optometristphoenixaz.com/&emv_key=F9X7CqqshZGf8SA9MKJi8NUY54O102IMNfcStGb5lw8W0bBhOG5mpqVsje_HhdA0lliq

    May 19, 2021 at 03:35 | Report abuse | Reply
  30. Local Marketing Jobs Near Me

    http://dereferer.org/?https://curtismelancon.com/

    May 19, 2021 at 04:53 | Report abuse | Reply
  31. Contacts Exam Near Me

    May I simply just say what a comfort to discover somebody that actually knows what they are talking about on the web. You actually understand how to bring an issue to light and make it important. More and more people must read this and understand this side of the story. It's surprising you aren't more popular given that you certainly possess the gift.

    https://trackings.oxfamintermon.org/click.php?campanya=SYD1612_S0310_03126_0001&data_enviament=20161207&desti=https://eyedoctorphoenixaz.com/

    May 19, 2021 at 04:57 | Report abuse | Reply
  32. Video Marketing Videos

    http://track.affclkr.com/track/clicks/3171/c627c2b89e0522dbfe9cbd2e8d2b8914736245cb75e9f0ab416db1046005?t=postfallslocal.com/

    May 19, 2021 at 05:56 | Report abuse | Reply
  33. Maserati Sara Jay

    http://www.islulu.com/link.php?url=https://www.maseratiforum.net/

    May 19, 2021 at 06:12 | Report abuse | Reply
  34. GtnbCrulk

    is viagra over the counter usa https://jokviagra.com/ viagra pills for men

    May 19, 2021 at 06:22 | Report abuse | Reply
  35. Best Vision Doctors Near Me

    This is a great tip particularly to those new to the blogosphere. Brief but very precise information… Thanks for sharing this one. A must read post!

    https://www.vpdacha.ru/_snippet/redirector.php?url=https://eyedoctorphoenixaz.com

    May 19, 2021 at 07:39 | Report abuse | Reply
  36. Vision Appointment Near Me

    There's certainly a lot to find out about this subject. I like all the points you have made.

    http://crl.ucsd.edu/cgi-bin/ax.cgi?http://sunglasseseyedoctorsoptometristphoenixaz.com

    May 19, 2021 at 07:54 | Report abuse | Reply
  37. Maserati Dealers Chicago

    I love reading through a post that will make people think. Also, thank you for allowing for me to comment!

    http://sitecheck.elinkdesign.com/redirect.php?url=http://club-maserati.com/

    May 19, 2021 at 09:24 | Report abuse | Reply
  38. RebfZisse

    cialis pharmacy mastercard http://rcialisgl.com/ cialis & viagra

    May 19, 2021 at 10:01 | Report abuse | Reply
  39. Printing Companies Near Me

    http://www.10lowkey.us/UCH/link.php?url=http://www.360branded.com/

    May 19, 2021 at 10:24 | Report abuse | Reply
  40. RV Upholstery California

    It’s hard to find educated people for this subject, but you seem like you know what you’re talking about! Thanks

    https://cloudsso.hikvision.com/logout?service=http://homelyhammock.com/ms/blog/15_The-Arabic-Alphabet-Activity-Pack.html

    May 19, 2021 at 13:17 | Report abuse | Reply
  41. Nearest Mercedes Service Center

    Good info. Lucky me I recently found your website by chance (stumbleupon). I've saved as a favorite for later!

    https://passport.sfacg.com/LoginOut.aspx?Returnurl=https://ocrv.tv/

    May 19, 2021 at 16:00 | Report abuse | Reply
  42. RV Flooring California

    After checking out a few of the blog posts on your blog, I honestly appreciate your technique of writing a blog. I book-marked it to my bookmark site list and will be checking back in the near future. Please visit my web site too and let me know how you feel.

    http://blackfive.net/__media__/js/netsoltrademark.php?d=trimsarl.com/component/k2/item/156-lipsum-loror-dit/156-lipsum-loror-dit?start=850960

    May 19, 2021 at 16:10 | Report abuse | Reply
  43. rv interior remodeling companies

    I blog often and I really thank you for your content. This great article has really peaked my interest. I am going to book mark your website and keep checking for new information about once per week. I subscribed to your RSS feed as well.

    http://www.10lowkey.us/UCH/link.php?url=https://dalton1z5v3.blogsvila.com/3493812/about-rv-service-near-me

    May 19, 2021 at 17:50 | Report abuse | Reply
  44. RV Storage Orange County

    /

    May 19, 2021 at 18:23 | Report abuse | Reply
  45. LebnEncox

    trusted online pharmacy reviews https://xlnpharmacy.com/ online pharmacy uk

    May 19, 2021 at 18:49 | Report abuse | Reply
  46. RV Fiberglass Riverside

    Good day! I could have sworn I’ve been to this website before but after browsing through a few of the posts I realized it’s new to me. Regardless, I’m certainly pleased I found it and I’ll be bookmarking it and checking back frequently!

    /

    May 19, 2021 at 21:08 | Report abuse | Reply
  47. Digital Marketing Specialist

    https://blogranking.fc2.com/out.php?id=414788&url=https://internetmarketingsupply.com/

    May 19, 2021 at 22:49 | Report abuse | Reply
  48. roof repair orange county ca

    I must thank you for the efforts you've put in penning this website. I am hoping to check out the same high-grade content by you in the future as well. In fact, your creative writing abilities has encouraged me to get my very own site now 😉

    http://wmcasher.ru/out.php?url=https://mariavcastellanos.com/?p=343701

    May 20, 2021 at 00:33 | Report abuse | Reply
  49. Local Marketing Agencies Near Me

    I'd like to thank you for the efforts you've put in writing this blog. I am hoping to see the same high-grade content by you later on as well. In truth, your creative writing abilities has motivated me to get my own site now 😉

    http://www.dev-skanvor.1gb.ru/redir.php?url=https://bulknearme.com/

    May 20, 2021 at 05:21 | Report abuse | Reply
  50. SEO Marketing Agencies

    The very next time I read a blog, I hope that it won't fail me just as much as this particular one. I mean, I know it was my choice to read, however I really thought you would probably have something useful to talk about. All I hear is a bunch of complaining about something you could fix if you were not too busy looking for attention.

    http://www.nozokinakamuraya.com/index.php?sbs=11679-1-140&page=https://bestservicenearme.com/

    May 20, 2021 at 05:53 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27

Leave a Reply to du ket qua bong da hom nay


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

« Previous entry
Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.

Archive
November 2011
M T W T F S S
 123456
78910111213
14151617181920
21222324252627
282930  
  • An error has occurred, which probably means the feed is down. Try again later.