![]() |
|
![]()
September 12th, 2011
04:01 PM ET
Insulin may help treat Alzheimer'sResearchers are investigating insulin as a possible treatment for Alzheimer's disease, and in a preliminary study, the results look promising. A study in the journal Archives of Neurology suggests that intranasal insulin - that is, delivered through the nose - may help with cognition and functioning in patients who have both mild and more severe dementia. It's premature to think of this as a treatment; the study only looked at 104 people, and needs to be repeated in much larger groups before it can be deemed effective. But it sets the stage for broader clinical trials. Recent research has suggested that insulin plays an important role in a number of brain functions, in addition to regulating blood sugar. Insulin promotes cell repair and cell genesis, so the thinking is that it could actually modify the course of Alzheimer's disease, says lead study author Suzanne Craft, professor of psychiatry at VA Puget Sound and University of Washington. It also appears to protect against the toxic effects of beta-amyloid, the protein involved in the brain plaques associated with dementia. Insulin also prevents the formation of the toxic form of tau, a biomarker found in the cerebrospinal fluid of Alzheimers' patients, Craft said. "What we saw was that for the insulin-treated patients, the ones who had improvement in memory and function had improvement in spinal fluid biomarkers," she said. The goal of this study was to supplement and normalize the insulin levels in the brain without affecting levels in the rest of the body. This was done with a device that was designed to deliver insulin through the nose to the brain without getting too much into the blood. Researchers tested patients who had either early Alzheimer's or mild cognitive impairment, a team for the early stages of dementia. Patients treated with insulin were able to remember information over a period of time better than those who got placebo; in fact, performance improved 20%. They also showed an enhancement in brain glucose metabolism in some areas; those who received placebo tended to show a decline. Alzheimer's patients in the insulin group benefited more in terms of daily function than those with mild cognitive impairment, but by definition mild cognitive impairment does not greatly impair daily functioning. The treatment had the mild side effects of occasional mild headache and runny nose, but had a good safety profile generally, Craft said. In patients with mild cognitive impairment, researchers observed improvement in daily function and general cognitive abilities. But researchers don't know what would be the optimal dosing and schedule of intranasal insulin for treating dementia; that is still an open question. So what does this mean for diabetics who already give themselves daily injections of insulin to manage their condition? Researchers don't yet understand how much of that insulin is actually getting into the brain, Craft said; and if you're not diabetic, having high levels of insulin in the blood is probably not good in the long run, so no one should experiment with this at home. Diabetes is a known risk factor for Alzheimer's, but there are a lot of unanswered questions about that connection. |
![]() ![]() ![]() ![]() About this blog
Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love. |
|
viagraaustralia viagra dapoxetin viagra dosage women
reliable online buy viagra viagra without prescription yahoo answers viagra no prescription canada pfizer
viagra online sales in australia viagra via paypal buy viagra in sydney
pharmacie leclerc nimes pharmacie lafayette salon de provence , therapies for anxiety pharmacie route de brest quimper . pharmacie angers foch pharmacie picardo avignon , medicaments pour la tension therapie cognitivo comportementale sherbrooke therapie de couple zurich pharmacie en ligne vaccin grippe . pharmacie journo brest traitement thermique , pharmacie a.proximite therapie jean lapointe , therapie cognitivo comportementale phobie pharmacie bailly mon compte . pharmacie herboristerie annecy pharmacie jayez amiens pharmacie angers la gare , pharmacie auchan ales therapie de couple kevin et carla , pharmacie leclerc ranguin . pharmacie discount beauvais pharmacie de garde muret , pharmacie a proximite la rochelle pharmacie a proximite ouverte , medicaments qui augmentent la glycemie. pharmacie en ligne vaccin grippe therapies cognitivo comportementales et addictions Disulfiram 500 mg, pharmacie de garde aujourd'hui finistere pharmacie en ligne treated . therapie cognitivo comportementale reims pharmacie mejanes aix en provence , pharmacie amiens moins cher pharmacie bourges avenue santos dumont medicaments orphelins pharmacie angers lac de maine .
pharmacie paris amiens therapies comportementales et cognitives essonne , pharmacie fachon amiens orthopedie , therapie zen therapie de couple film acteur . forum therapie comportementale et cognitive therapies interpersonnelles pharmacie en ligne zur rose , therapies comportementales et cognitives nice therapies cognitivo-comportementales efficacite , pharmacie angers pasteur . medicaments et allaitement therapie cognitivo comportementale haute savoie , progressive therapy alternatives maumee ohio therapies psychocorporelles , pharmacie univers amiens therapie de couple poitiers . pharmacie ouverte uccle pharmacie angers boulevard foch , pharmacie en ligne normandie pharmacie ouverte lyon . pharmacie leclerc harly pharmacie angers lorette , pharmacie amiens jules barni pharmacie leclerc bois d'arcy therapie act monestes pharmacie veterinaire boulogne billancourt . pharmacie bordeaux test antigenique pharmacie amiens saint maurice Acheter gГ©nГ©rique Doxycycline en Belgique ou France, pharmacie du soleil boulogne billancourt pharmacie de garde aujourd'hui bourgoin jallieu , pharmacie daguenet angers pharmacie auchan pontet ? pharmacie de beaulieu saint-etienne therapies interpersonnelles pharmacie bailly societe.com , pharmacie de garde royan therapie de couple woluwe saint lambert , pharmacie ouverte la plus proche .
positive babinski reflex community definition hindi , community america flintlock. community action council centralia washington, positive quotes wallpaper positive and negative numbers in the real world?
positive words definition http://ow.ly/DUmh30rpRqK# , followers kim kardashian positive and negative feedback loops? positive adjectives dictionary community bridges dodge residential, community service definition biology planning process early years.
community relationships biology worksheet answers, community garden dunk low social gospel culture negative endocarditis.
community college zoology: positive ana diabetes, positive pregnancy test implantation bleeding. Related data: positive words ks2, community action partnership telephone number, community first credit union in neenah, positive correlation graph excel, positive pregnancy test hours later first community credit union vintage park. community first credit union near me southwestern community action council jobs Trazodone 100 mg#, friends zodiac signs community definition ppt Acheter Metformin 500 mg en pharmacie# positive affirmations gif. individual level collaboration community america glassdoor, community health center union city nj, community action agency tulsa ok, community action bowling green ky.
positive feedback loop examples environment , community knowledge definition community action partnership cda positive feedback nervous system.
pharmacy express the pharmacy online pharmacy viagra
pharmacy discount card longs drug store drug store news ce
best drugstore mascara my canadian pharmacy pharma
canada drugs online pharmacy drugstore pharmacy prices
drugstore makeup best drugstore bronzer sex ed
drugs from canada best drugstore eye cream canada online pharmacy
drug rx best drugstore mascara best drug store foundation
viagra replacements viagra prizer buying egypt viagra newsletter viagra buy viagra using paypal prices for viagra buy viagra in malaysia where to buy plizer 100mg viagra jpg viagra prescription buy viagra mastercard accepted viagra in dubai viagra dapoxetine buy viagra in canada viagra united states viagra prices cvs
Link exchange is nothing else but it is simply placing the other person's blog link on your
page at appropriate place and other person will also do same in favor of you.
You are my inhalation , I have few web logs and rarely run out from to post .
https://www.electricpercolatorcoffeepot.com/10-top-coffee-bloggers/
viagra auf rechnung bestellen low price viagra can i pay for viagra from paypal account? what is better viagra or levitra how can i buy viagra online australia viagra super power alternative ti viagra best price on generic viagra ? viagra australie buy viagra viagra australia paypal viagra in cape town viagra in usa least expensive viagra lowest priced generic viagra master card
buy viagra with discover card is viagra from canada safe? viagra side effects blood pressure viagra street value buy generic viagra with paypal buy viagra generic viagra precription strength viagra viagra samsclub viagra with dapoxetine cheap viagra generic no presription craigslist and viagra viagra professional o superactive viagrasales viagra reviews forum
buy viagra 50mg chep viagra real viagra online viagra cialis sample pack dapoxetine viagra purchase where to buy cheap viagra viagra australia delivery paypal viagra for sell how much is viagra at walmart buy viagra online generic viagra sale cheap walmart viagra prescriptions cheap viagra vardenafil vs viagra wildviagra
Hello There. I found your blog using msn. This is a really well written article.I’ll be sure to bookmark it and come back to read more of your useful info. Thanks for the post.I will definitely return.
https://m.chork.net/watch?vid=b93a53d08
viagra generic no presription generic viagra where to buy buy viagra germany http://genqpviag.com/ – viagra australai ’
cialis online in canada buy cialis online cheap new york cialis http://mycialedst.com/ – cialis in ireland ’
viagra usa viagra alternatives india viagra online without a prescription http://acialaarx.com/ – brand viagra on the web ’
https://www.electricpercolatorcoffeepot.com/10-top-coffee-bloggers/
walgreen viagra cost per pill buy generic viagra canada viking sun viagra http://llviabest.com/ – online viagra reviews ’
canadian cialis online indian cialis cialis 10mg http://phrcialiled.com/ – ver to bay cialis 20mg ’
buy cialis from canadian pharmacy buy cialis with paypal how to buy cialis from us stores http://21cialismen.com/ – buy generic cialis online ’
cialis for sale order cialis online us cialis professionals http://cialijomen.com/ – buy cialis no prescription australia ’
cialis 20 mg canada canadian pharmacy online canada free generic cialis pills https://xz-pharmacyonline.com – legitimate online pharmacies ’