FDA recommends lowering Celexa's maximum daily dose
August 25th, 2011
12:51 PM ET

FDA recommends lowering Celexa's maximum daily dose

The Food and Drug Administration is recommending that patients taking the anti-depressant Celexa (citalopram hydrobromide) take no more than 40mg a day. The FDA says anything more can cause abnormal heart rhythms, and studies show there is no therapeutic benefit with doses higher than 40mg. The recommendation includes generic versions of the drug.

Celexa, is made by Forest Laboratories Inc., and is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Serotonin is a neurotransmitter–it helps relay messages from one part of the brain to another. Researchers believe serotonin imbalances can influence your mood and lead to depression. SSRIs like Celexa increase the amount of serotonin in the brain, which can help improve mood.

Although the drug is available in 10mg, 20mg and 40mg pills, 60mg doses can be used to treat certain patients with depression.

"Most patients are treated with lower doses of Celexa," Sandy Walsh, FDA spokesperson said. "But we issued the safety communication today [Wednesday] to make sure doctors and patients have the most up to date information possible to make treatment decisions."

The FDA says at-risk patients include "those with underlying heart conditions and those who tend to have low levels of potassium and magnesium in their blood."

The  safety announcement warns doctors not to prescribe the drug for patients with congenital long QT syndrome (LQTS)–a condition of the heart's electrical system that can lead to cardiac arrest or sudden death. LQTS is rare–only about 1 in 5,000 Americans have the condition.

Patients, the agency says, should not stop taking Celexa or change their dose without first talking to their doctor.  Stopping suddenly can cause side effects. Any patient who has shortness of breath, irregular heartbeat or dizziness while taking the medication should see their doctor.

soundoff (2,342 Responses)
  1. 먹튀

    Hi! I could have sworn Iíve visited this web site before but after going through some of the posts I realized itís new to me. Anyhow, Iím certainly delighted I found it and Iíll be book-marking it and checking back frequently!


    May 8, 2021 at 08:43 | Report abuse | Reply
  2. Nicki Inoa

    I am often to blogging and i truly appreciate your content. The write-up has actually peaks my interest. I am going to bookmark your website and maintain checking for new data.


    May 8, 2021 at 10:14 | Report abuse | Reply
  3. Digital Marketing California

    Aw, this was a really nice post. Spending some time and actual effort to generate a really good article… but what can I say… I procrastinate a lot and don't seem to get anything done.


    May 8, 2021 at 10:16 | Report abuse | Reply
  4. Erick Salazan

    The Notebook is of course one of Nick Sparks best tear jearker novel. Nick is really very talented guy;


    May 8, 2021 at 12:49 | Report abuse | Reply
  5. Social Media Marketing Company

    Pretty! This was an extremely wonderful article. Thank you for supplying this info.


    May 8, 2021 at 13:48 | Report abuse | Reply
  6. chloroquine phosphate generic name

    chloroquine amazon https://chloroquineorigin.com/ cloraquine

    May 8, 2021 at 13:55 | Report abuse | Reply
  7. Digital Marketing Job

    Excellent site you have got here.. It’s difficult to find good quality writing like yours these days. I honestly appreciate individuals like you! Take care!!


    May 8, 2021 at 15:24 | Report abuse | Reply
  8. Internet Marketing Pros


    May 8, 2021 at 20:14 | Report abuse | Reply
  9. Social Media Marketing Firm

    Hi there! This blog post couldn’t be written much better! Reading through this article reminds me of my previous roommate! He continually kept talking about this. I'll forward this information to him. Pretty sure he will have a great read. Thanks for sharing!


    May 8, 2021 at 21:23 | Report abuse | Reply
  10. Jeanett Eppley

    I will right away clutch your rss feed as I can't find your email subscription hyperlink or e-newsletter service. Do you've any? Kindly permit me recognize in order that I may just subscribe. Thanks.


    May 8, 2021 at 22:50 | Report abuse | Reply
  11. Social Media Marketing Near Me

    Can I simply say what a comfort to find someone that actually understands what they're talking about online. You certainly know how to bring an issue to light and make it important. More people should look at this and understand this side of the story. I can't believe you aren't more popular since you certainly possess the gift.


    May 9, 2021 at 01:58 | Report abuse | Reply
  12. Digital Marketing Consultants


    May 9, 2021 at 04:18 | Report abuse | Reply
  13. Digital Marketing Specialists

    Very good article. I'm facing a few of these issues as well..


    May 9, 2021 at 12:34 | Report abuse | Reply
  14. Alise Kaye

    My brother recommended I might like this blog. He was totally right. This publish actually made my day. You can not believe simply how so much time I had spent for this information! Thanks!


    May 9, 2021 at 12:43 | Report abuse | Reply
  15. 먹튀검증사이트

    Way cool! Some very valid points! I appreciate you writing this write-up and the rest of the website is really good.


    May 9, 2021 at 13:40 | Report abuse | Reply
  16. RV Entertainment System Near Me


    May 9, 2021 at 14:17 | Report abuse | Reply
  17. RV Roof Riverside

    Saved as a favorite, I really like your blog!


    May 9, 2021 at 15:17 | Report abuse | Reply
  18. 먹튀

    Everything is very open with a really clear clarification of the issues. It was really informative. Your website is very useful. Thanks for sharing!


    May 9, 2021 at 17:32 | Report abuse | Reply
  19. 먹튀검증커뮤니티

    I'm more than happy to find this site. I wanted to thank you for ones time for this particularly fantastic read!! I definitely savored every little bit of it and I have you saved as a favorite to check out new things on your site.


    May 9, 2021 at 18:23 | Report abuse | Reply
  20. Google Marketing Program


    May 9, 2021 at 18:41 | Report abuse | Reply
  21. Internet Marketing Jobs Near Me

    Good information. Lucky me I ran across your website by accident (stumbleupon). I have book marked it for later!


    May 9, 2021 at 19:31 | Report abuse | Reply
  22. 먹튀검증사이트

    Great web site you have here.. Itís hard to find excellent writing like yours nowadays. I really appreciate individuals like you! Take care!!


    May 9, 2021 at 21:10 | Report abuse | Reply
  23. Annamaria Deihl

    I bookmared your site a couple of days ago coz your blog impresses me.;`~”-


    May 9, 2021 at 21:58 | Report abuse | Reply
  24. Internet Marketing Services Near Me

    Good post. I learn something new and challenging on sites I stumbleupon every day. It will always be useful to read through content from other writers and practice something from other sites.


    May 9, 2021 at 21:58 | Report abuse | Reply
  25. 먹튀검증커뮤니티

    Good info. Lucky me I ran across your website by chance (stumbleupon). I have saved as a favorite for later!


    May 10, 2021 at 01:45 | Report abuse | Reply
  26. 먹튀검증업체

    There is definately a lot to find out about this subject. I love all of the points you have made.


    May 10, 2021 at 05:57 | Report abuse | Reply
  27. 먹튀검증

    Excellent site you have got here.. Itís hard to find quality writing like yours nowadays. I really appreciate people like you! Take care!!


    May 10, 2021 at 11:38 | Report abuse | Reply
  28. Local Marketing Companies Near Me


    May 10, 2021 at 13:56 | Report abuse | Reply
  29. Reyes Kihlstrom

    An impressive share, I just given this onto a colleague who was doing just a little evaluation on this. And he actually purchased me breakfast as a result of I discovered it for him.. smile. So let me reword that: Thnx for the treat! However yeah Thnkx for spending the time to discuss this, I feel strongly about it and love studying extra on this topic. If possible, as you turn out to be experience, would you thoughts updating your blog with more details? It's extremely helpful for me. Large thumb up for this blog put up!


    May 10, 2021 at 14:02 | Report abuse | Reply
  30. 먹튀검증

    Spot on with this write-up, I honestly believe this web site needs far more attention. Iíll probably be returning to read more, thanks for the information!


    May 10, 2021 at 16:44 | Report abuse | Reply
  31. Content Marketing Quotes


    May 10, 2021 at 16:44 | Report abuse | Reply
  32. Seo Marketing Deal

    An outstanding share! I have just forwarded this onto a co-worker who had been doing a little research on this. And he in fact ordered me lunch due to the fact that I discovered it for him... lol. So let me reword this.... Thanks for the meal!! But yeah, thanks for spending the time to talk about this issue here on your website.


    May 10, 2021 at 19:45 | Report abuse | Reply
  33. Social Media Marketing Events

    This site certainly has all of the information I wanted about this subject and didn’t know who to ask.


    May 10, 2021 at 19:53 | Report abuse | Reply
  34. 먹튀검증업체

    An outstanding share! I have just forwarded this onto a co-worker who was conducting a little homework on this. And he in fact ordered me lunch due to the fact that I discovered it for him... lol. So allow me to reword this.... Thank YOU for the meal!! But yeah, thanks for spending the time to discuss this subject here on your internet site.


    May 10, 2021 at 20:00 | Report abuse | Reply
  35. 먹튀검증

    I blog quite often and I truly thank you for your content. The article has truly peaked my interest. I am going to take a note of your site and keep checking for new details about once per week. I opted in for your Feed too.


    May 10, 2021 at 21:55 | Report abuse | Reply
  36. 먹튀검증

    Great information. Lucky me I discovered your website by accident (stumbleupon). I've saved as a favorite for later!


    May 10, 2021 at 23:50 | Report abuse | Reply
  37. 먹튀

    Iím amazed, I have to admit. Seldom do I come across a blog thatís both equally educative and amusing, and let me tell you, you have hit the nail on the head. The issue is an issue that too few men and women are speaking intelligently about. Now i'm very happy I stumbled across this during my hunt for something regarding this.


    May 11, 2021 at 00:09 | Report abuse | Reply
  38. 먹튀검증업체

    Everything is very open with a clear description of the issues. It was definitely informative. Your website is useful. Thanks for sharing!


    May 11, 2021 at 00:27 | Report abuse | Reply
  39. Social Media Marketing Events

    Hi, I do believe this is an excellent web site. I stumbledupon it 😉 I may come back once again since i have book-marked it. Money and freedom is the best way to change, may you be rich and continue to help other people.


    May 11, 2021 at 00:30 | Report abuse | Reply
  40. Russell Belstad

    Thank you so much for providing individuals with an extraordinarily remarkable opportunity to read from this website. It really is very sweet and also stuffed with amusement for me and my office co-workers to visit your blog at minimum thrice a week to read through the latest tips you have. Not to mention, we are always contented for the powerful information you give. Some 1 areas in this article are unequivocally the most suitable we've ever had.


    May 11, 2021 at 04:06 | Report abuse | Reply
  41. 먹튀검증사이트

    Good day! I could have sworn Iíve been to this web site before but after going through a few of the posts I realized itís new to me. Anyways, Iím certainly delighted I discovered it and Iíll be book-marking it and checking back frequently!


    May 11, 2021 at 04:27 | Report abuse | Reply
  42. Video Marketing Videos

    The very next time I read a blog, I hope that it doesn't disappoint me as much as this particular one. I mean, I know it was my choice to read through, however I really thought you'd have something interesting to talk about. All I hear is a bunch of crying about something that you could fix if you were not too busy seeking attention.


    May 11, 2021 at 10:01 | Report abuse | Reply
  43. 먹튀검증

    Hello there! This article couldnít be written any better! Reading through this post reminds me of my previous roommate! He constantly kept preaching about this. I'll send this information to him. Fairly certain he'll have a very good read. Thank you for sharing!


    May 11, 2021 at 10:56 | Report abuse | Reply
  44. Google Marketing Jobs

    Excellent article. I certainly love this website. Continue the good work!


    May 11, 2021 at 14:44 | Report abuse | Reply
  45. 먹튀검증사이트

    Spot on with this write-up, I truly feel this website needs a great deal more attention. Iíll probably be returning to see more, thanks for the info!


    May 11, 2021 at 16:35 | Report abuse | Reply
  46. 먹튀검증

    You should take part in a contest for one of the greatest websites on the net. I am going to recommend this website!


    May 11, 2021 at 17:05 | Report abuse | Reply
  47. Internet Marketing Business


    May 11, 2021 at 17:45 | Report abuse | Reply
  48. Best Tucker Sprinter Repair

    That is a good tip especially to those new to the blogosphere. Simple but very precise information… Thanks for sharing this one. A must read post!


    May 11, 2021 at 19:25 | Report abuse | Reply
  49. rv renovation companies near me


    May 11, 2021 at 22:12 | Report abuse | Reply
  50. motorhome mechanic near me

    The next time I read a blog, I hope that it doesn't disappoint me just as much as this one. I mean, I know it was my choice to read through, however I actually believed you'd have something useful to say. All I hear is a bunch of whining about something that you can fix if you were not too busy seeking attention.


    May 11, 2021 at 23:48 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47

Post a comment


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.