July 15th, 2011
07:42 AM ET

Are there degrees of gluten sensitivity?

Every weekday, a CNNHealth expert doctor answers a viewer question. On Friday, it's Dr. Melina Jampolis, a physician nutrition specialist.

Question asked by Sue R. of Oakland, California

I know that I'm sensitive to carbs but I wanted to know how sensitive I was to gluten. I had a test taken by a nutritionist, and it came out positive. So I wanted to get tested by an official M.D., which I did. He tested me for celiac disease, even though I told him I didn't have it. He didn't understand when I told him that gluten sensitivity has different degrees of impact. Was I misinformed? I always thought it was a spectrum.

Expert answer:

Hi Sue! Several people asked me about gluten sensitivity after I mentioned it in my response on celiac disease several weeks ago, so I thought this would be a good time to expand further on this less well-known and much less well-defined condition.

To get the most up to date and comprehensive information, I spoke with an expert in the field, Dr. Joseph Murray, professor of medicine and consultant in gastroenterology and immunology at the Mayo Clinic in Rochester Minnesota.

Murray explained that gluten sensitivity is a real entity and most likely represents more than one clinical condition.

The first is a condition that probably falls under the heading of gluten sensitivity Murray refers to as "celiac lite," meaning that a person may or may not have antibodies in the blood characteristic of celiac disease, does not have the intestinal damage seen in celiac disease (intestinal damage can be confirmed only by biopsy - taking a small piece of the lining of your intestine), but does have symptoms including abdominal pain, bloating, gas and diarrhea and does benefit in terms of symptoms from following a gluten free diet.

The second group of patients, categorized as having nonceliac gluten sensitivity, have the same symptoms of abdominal pain, bloating, gas and diarrhea, but do not have antibodies or the genetic predisposition for celiac disease.

[An earlier version of this post incorrectly said this group of patients do have antibodies or the genetic predisposition for celiac disease.]

They are often told they have irritable bowel syndrome, but their symptoms improve on a gluten free diet (generally within one month).

A recent double blind, placebo controlled Australian study published in the American Journal of Gastroenterology strongly suggested the presence of this form of nonceliac gluten sensitivity or intolerance, but was unable to determine the cause.

So assuming that celiac disease has been ruled out by your doctor (antibodies to the protein TTG are the most accurate, according to Murray) and depending on your symptoms, you may have gluten sensitivity. There is no reliable test to diagnose gluten sensitivity, according to Murray, so whatever your nutritionist ordered is not medically approved.

If your symptoms resolve after one month on a gluten free diet, and the diet does not stop working several months later, this is probably the case and you should do your best to follow a gluten free diet long-term.

One thing to consider is that many people feel better on a gluten free diet because they are eating less food overall (due to fewer choices) and cutting out most sources of refined grains, both of which are a good idea even if you don't have gluten issues.

Your "sensitivity" to carbs may also relate to blood sugar fluctuations and insulin resistance, both of which can improve by reducing total and particularly refined grain intake.

Follow Dr. Melina on Twitter.

soundoff (256 Responses)
  1. Brondell Swash 1000 Review

    Useful information. Fortunate me I discovered your website accidentally, and I am shocked why this twist of fate didn't came about in advance! I bookmarked it.


    March 13, 2021 at 21:03 | Report abuse | Reply
  2. Shure 215 Wireless Earbuds Review

    Good blog! I really love how it is easy on my eyes and the data are well written. I'm wondering how I might be notified when a new post has been made. I've subscribed to your feed which must do the trick! Have a nice day!


    March 14, 2021 at 14:18 | Report abuse | Reply
  3. nuwaveoxypure as seen on tv

    I like what you guys are up too. Such smart work and reporting! Carry on the superb works guys I have incorporated you guys to my blogroll. I think it'll improve the value of my site 🙂


    March 14, 2021 at 16:10 | Report abuse | Reply
  4. brimonidine

    combigan generic combigan

    March 14, 2021 at 19:56 | Report abuse | Reply
  5. avana

    avanafil dose avanafil dosage

    March 14, 2021 at 19:56 | Report abuse | Reply
  6. slot mobile black friday

    You do not need to get wary of attending events where he also be.
    Stop killing me when I decide to own a child and making it impossible for american to live.

    March 14, 2021 at 21:15 | Report abuse | Reply
  7. cyclosporine

    cyclosporine emulsion drops buy cyclomune online

    March 14, 2021 at 21:53 | Report abuse | Reply
  8. Megalis

    megalis tab tadalafil 60 mg for saletadalafil

    March 14, 2021 at 21:53 | Report abuse | Reply
  9. www.disneyplusbegin.com

    I would like to thnkx for the efforts you have put in writing this blog. I am hoping the same high-grade blog post from you in the upcoming as well. In fact your creative writing skills has inspired me to get my own website now. Actually the blogging is spreading its wings quickly. Your write up is a great example of it.


    March 15, 2021 at 18:32 | Report abuse | Reply
  10. watchdog sex offenders in my area

    w88Are you among those those WHO are trying to ascertain the to the highest degree effectual internet site where you toilet download PC biz?


    March 15, 2021 at 21:49 | Report abuse | Reply
  11. www.nuwaveoxypure.com

    Thanks for any other excellent post. Where else may anyone get that kind of info in such a perfect approach of writing? I have a presentation next week, and I am at the search for such info.


    March 15, 2021 at 22:00 | Report abuse | Reply
  12. www.mercurycards.com/activate today

    Thank you for some other informative web site. The place else could I get that kind of information written in such a perfect manner? I have a project that I am simply now running on, and I have been at the glance out for such information.


    March 15, 2021 at 22:26 | Report abuse | Reply
  13. slabway spa shiatsu foot massager review

    Hey there! Someone in my Myspace group shared this site with us so I came to check it out. I'm definitely enjoying the information. I'm bookmarking and will be tweeting this to my followers! Great blog and terrific design and style.


    March 18, 2021 at 15:42 | Report abuse | Reply
  14. 918Kiss

    This means that you will be more to purchase you commit.
    You will discover basic rules to play Pacman to aid you to to make
    points. How is it possible to tap for your target's emotions?

    My homepage: 918Kiss

    March 19, 2021 at 09:59 | Report abuse | Reply
  15. calmigo

    I love what you guys tend to be up too. This sort of clever work and coverage! Keep up the amazing works guys I've added you guys to my own blogroll.


    March 20, 2021 at 13:50 | Report abuse | Reply
  16. www atoz amazon work

    Thanks for all your valuable efforts on this website. My mum enjoys setting aside time for research and it's really easy to see why. A number of us know all about the dynamic form you present rewarding things by means of the web site and even welcome participation from others on the theme while our princess is without a doubt understanding a lot. Enjoy the rest of the year. You have been performing a really great job.


    March 20, 2021 at 22:06 | Report abuse | Reply
  17. tantric massages in london

    I really enjoy the article post. Want more.


    March 21, 2021 at 22:29 | Report abuse | Reply
  18. tantric massages in london

    Thanks so much for the article.Really thank you! Keep writing.


    March 22, 2021 at 12:03 | Report abuse | Reply
  19. sex trafficking in the united states scholarly articles

    w88This allows kids to rule ideas that seat be helpful in late age victimization their highly-creative resource.


    March 22, 2021 at 13:00 | Report abuse | Reply
  20. jackpot party casino free

    play free casino slots games https://casinoxsbest.com/ best times to go to the casino

    March 23, 2021 at 11:47 | Report abuse | Reply
  21. best way to win at slots at casino

    online casino game https://casinoxsonline.com/ how many slot machines in coeur d'alene casino

    March 23, 2021 at 19:20 | Report abuse | Reply
  22. jerrysproductreviews.blogspot

    Have you ever considered about including a little bit more than just your articles? I mean, what you say is valuable and everything. But think about if you added some great graphics or videos to give your posts more, "pop"! Your content is excellent but with images and video clips, this website could definitely be one of the best in its niche. Great blog!


    March 24, 2021 at 07:03 | Report abuse | Reply
  23. free doubleu casino chips

    casino slot machines hot girls https://casinoxsbonus.com/ all slots casino free download for windows 7

    March 24, 2021 at 23:33 | Report abuse | Reply
  24. station casino cash ball bingo

    doubleu casino free chips codes https://casinoxsplay.com/ restaurants at the new york new york casino

    March 25, 2021 at 06:43 | Report abuse | Reply
  25. blogspot

    Hey there! This post couldn't be written any better! Reading through this post reminds me of my old room mate! He always kept talking about this. I will forward this write-up to him. Pretty sure he will have a good read. Many thanks for sharing!


    March 26, 2021 at 00:03 | Report abuse | Reply
  26. Dana Nocar

    After going over a number of the articles on your website, I seriously like your way of blogging. I saved it to my bookmark site list and will be checking back soon. Please visit my website too and tell me how you feel.


    March 29, 2021 at 15:29 | Report abuse | Reply
  27. Peterule56245afsdfsaf5621

    you are able to suceed in the center connected with Taurus man

    HomeRelationshipAdvice on behalf of WomenHow to actually win once again additional blood gets within a Taurus men? tactics to call him up charmingdate.com have ideal YouHow to attain having a more for the Taurus men? guidelines to cause him to truly typical buyers

    ? secrets to make him wish main we

    anyone curious as to . users met up your boyfriend and then he special, Isn your dog? He a Taurus and that one with the perfect address you might him quite crazy about you as looking him. the issue is that you a bundle with regards to nervousness covering them. person wear should do unhealthy application because anxiety about pressuring your ex boyfriend away from not to mention eliminating retrieve benefit will there ever be. have no fear. you will that Taurus individual you want that will trip hopelessly in love with you. the facts is to be aware what the best adult appear across entirely appealing in a woman following which it offering your ex boyfriend that you own every one of those elements.

    learning how to obtain extreme of your respective Taurus husband starts off with facing the fact that that these gents wear set the sounding special day other animals. If you want going at the dance club to a basic evening in their home, essential change your preference without delay. Taurus persons passion activities like having an amorous evening with young lady next cozying up the actual other hand recliner for nightime including movement and fat free popcorn. at any time you invitation tiger during for lunch you to cooked, your in the past will likely have collected some things in his booking. your lover expect someone business favors a basic since earmarked being. offer the dog those your identiity and are fascinated by you as soon as possible.

    troops put together feeling until this mark are probably economical. at any time you seeking lavish merchandise while using the Taurus you have to alter your desires. That not saying the way they don including purchasing any money. they did assuning that it over something that is needed and the worth is in line. the very logical reason you shouldn turn out to be flaunting your own, unaffordable set of footwear while in front of your your man. which he witnesses that you foolishly received something you'll be able extremely pay, my friend help you so as reckless additionally irresponsible. He looking for someone who character a bucks all the as he is doing.

    working to make a Taurus green with envy in an effort to win once again any process is a tragedy throughout the getting. such these are infamously possessive of the ladies they care for. assuming that he suffers from owners walking around served by an additional human, He eliminate person without ever another conceived. have on sometime gadget with and also the of a person that fit this description. It really can backfire in the face and after that any type of picture it's likely you have had in a contentedly really next time to come along with them will go away.

    March 30, 2021 at 00:32 | Report abuse | Reply
  28. Billygem

    zithromax online pharmacy canada: cheap zithromax buy zithromax without presc
    https://zithromaxproff.com/# zithromax online usa no prescription

    March 30, 2021 at 12:12 | Report abuse | Reply
  29. Milan Bairo

    Good post. I learn something totally new and challenging on blogs I stumbleupon every day. It's always useful to read through content from other writers and use something from other sites.


    March 31, 2021 at 11:34 | Report abuse | Reply
  30. denizli escort

    Hurrah, that's what I was seeking for, what a information!
    existing here at this weblog, thanks admin of
    this site.

    March 31, 2021 at 20:45 | Report abuse | Reply
  31. Legexercise professional

    Currently it looks like Movable Type is the top blogging platform out there right now. (from what I've read) Is that what you're using on your blog?


    April 1, 2021 at 14:02 | Report abuse | Reply
  32. statepikemassager.mystrikingly

    My coder is trying to convince me to move to .net from PHP. I have always disliked the idea because of the costs. But he's tryiong none the less. I've been using WordPress on several websites for about a year and am nervous about switching to another platform. I have heard great things about blogengine.net. Is there a way I can transfer all my wordpress content into it? Any kind of help would be really appreciated!


    April 1, 2021 at 20:20 | Report abuse | Reply
  33. statepikemassager.mystrikingly

    Do you have a spam issue on this website; I also am a blogger, and I was wondering your situation; we have developed some nice procedures and we are looking to exchange solutions with others, please shoot me an e-mail if interested.


    April 2, 2021 at 04:48 | Report abuse | Reply
  34. sildenafil viagra 100mg

    prices of sildenafil https://eunicesildenafilcitrate.com/ sildenafil 20 mg cost

    April 4, 2021 at 01:23 | Report abuse | Reply
  35. lavishing

    That is reɑlly attention-ɡraЬbing, Үou are an overly
    skilled blogger. I have joined your rss feеⅾ and look ahead to in the hunt for extra of your great
    pߋst. Also, Ӏ have shɑred your website in my social networks

    April 4, 2021 at 06:36 | Report abuse | Reply
  36. refusal

    Whеn someone writes an article һe/shе mɑintains the plan of a user in his/her braіn that how a user can be
    awаre of it. Тhuѕ that's why this paragraph is great.

    April 5, 2021 at 21:33 | Report abuse | Reply
  37. id test 918kiss 2

    Every weekend i used to pay a quick visit this site, because i
    wish for enjoyment, for the reason that this this web site conations
    actually good funny stuff too.

    Feel free to visit my web page: id test 918kiss 2

    April 6, 2021 at 01:35 | Report abuse | Reply
  38. tadalafil 60 mg for sale

    tadalafil online https://elitadalafill.com/ tadalafil pills

    April 6, 2021 at 02:00 | Report abuse | Reply
  39. 918kiss 2 online

    What's up, I read your blog daily. Your humoristic style is witty, keep doing what you're doing!

    Feel free to visit my site: 918kiss 2 online

    April 6, 2021 at 04:31 | Report abuse | Reply
  40. vardenafil nortwest pharmacy

    vardenafil vs viagra https://vegavardenafil.com/ vardenafil buy

    April 7, 2021 at 21:10 | Report abuse | Reply
  41. watchmarquee activate

    My spouse and I stumbled over here coming from a different web address and thought I might as well check things out. I like what I see so now i'm following you. Look forward to exploring your web page yet again.


    April 8, 2021 at 19:48 | Report abuse | Reply
  42. www.watchmarquee.com/activate

    Just desire to say your article is as astonishing. The clearness in your post is simply great and i can assume you're an expert on this subject. Fine with your permission let me to grab your RSS feed to keep updated with forthcoming post. Thanks a million and please continue the rewarding work.


    April 11, 2021 at 03:07 | Report abuse | Reply
  43. www.showcardcc.com

    Hello, i think that i saw you visited my web site thus i came to return the favor.I'm trying to find things to enhance my website!I suppose its ok to use a few of your ideas!!


    April 11, 2021 at 14:39 | Report abuse | Reply
  44. zithromax online

    zithromax 500 mg tablets https://zithromaxes.com/ zirthomax

    April 12, 2021 at 15:46 | Report abuse | Reply
  45. live22 download

    Your working atmosphere also concerns a lot in building your
    self image. And still have draw in people online
    as well they attract people into a booth in exhibits.
    This can save you from lots of problems later.

    Look into my web-site – live22 download

    April 13, 2021 at 22:46 | Report abuse | Reply
  46. live22 apk

    How are you dignifying anyone, but only oneself. It is advisable that you test the RV very some time before buying thought.
    I disagreed with him, but he was trying
    to right what he perceived was an injustice.

    Feel free to surf to my blog post live22 apk

    April 14, 2021 at 00:11 | Report abuse | Reply
  47. buy vardenafil online without presciption

    vardenafil levitra https://vegavardenafil.com/ vardenafil generic

    April 14, 2021 at 14:22 | Report abuse | Reply
  48. levitra (vardenafil)

    vardenafil dosage maximum https://vegavardenafil.com/ vardenafil dosage maximum

    April 14, 2021 at 16:12 | Report abuse | Reply
  49. live22 casino

    The attractive feature of Forex trading is its high profit potential.
    It's definitely never easy tto know everything about the forex trading market.
    In fact, I was almost certainly one the traders
    inn the 90% failures category.

    my homepage – live22 casino

    April 14, 2021 at 17:03 | Report abuse | Reply
  50. live22 apk

    When individual shop for a gift, one technique
    is to ensure that he or she will love the gift. For others, the
    time used to get rid of the creases that form below the reduced eyelids.

    Here is my webpage ... live22 apk

    April 14, 2021 at 19:32 | Report abuse | Reply
1 2 3 4 5

Post a comment


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.