![]() |
|
![]()
May 18th, 2011
05:05 PM ET
Stop selling higher dose Alzheimer's drug, group saysA specific dose of Alzheimer’s drug should be pulled from the market because it poses a risk to patients, according to a consumer group. The drug, donepezil, sold under the brand Aricept, is administered in several doses – the highest being 23 milligrams – for patients with moderate to severe Alzheimer’s disease. It is prescribed to improve mental function, such as memory, attention and reasoning by increasing a brain chemical. Aricept which is taken daily, could slow the mental decline, but it does not cure or prevent Alzheimer's. The Public Citizen’s Health Research Group called the 23-milligram dose of Aricept “significantly more toxic” than the 10-milligram dose and said it “should be immediately withdrawn from the market.” The group says that the drug in higher dose compared with the 10-milligrams could pose increased adverse effects such as slowed pulse rate, nausea, vomiting, diarrhea, urinary incontinence, fatigue, dizziness and agitation. The group also said the higher dose does not appear to give any benefits to the patients. Patients often stop taking the higher dose because of its strong side effects such as vomiting. And Alzheimer’s patients are particularly sensitive to vomiting because it can lead to other problems such as pneumonia, massive gastrointestinal bleeding, esophageal rupture and even death, the group said. In response, Pfizer, which co-promotes Aricept with another company, Eisai, wrote in an emailed statement: "We are reviewing the petition and will respond accordingly; however, it is important to note that the Aricept (donepezil HCl) 23 mg tablet has been approved by the U.S. Food and Drug Administration for the treatment of moderate-to-severe Alzheimer’s disease. " Dr. James Lah, director of the cognitive neurology program at Emory University"s Department of Neurology, regularly prescribes Aricept to patients, but doesn't prescribe the 23-milligram dose. “Being Americans, the notion is that bigger is better, more is better... it’s simply not true in this particular instance,” Lah said. He said he was concerned when the FDA approved the 23-milligram version. “There is very little evidence that it’s superior,” Lah, an Alzheimer's clinician and associate professor said. “There is a lot of evidence that it’s worse in terms of causing side effects. If you look at the one study, only one clinical trial reported about the 23 versus 10 milligram Aricept. The results were entirely mixed in terms of effectiveness.” soundoff (35,738 Responses)« Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 695 696 697 698 699 700 701 702 703 704 705 706 707 708 709 710 711 712 713 714 715 Next »Leave a Reply to Davidssasw |
![]() ![]() ![]() ![]() About this blog
Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love. |
|
avanafil buy avana canada
side effects of tadalafil buy generic cialis online with mastercard buy cialis tadalafil cialis https://tadalafilol.com/ – cheapest tadalafil cost
значение рунах
ксго рун
руны гп
руны картинки значения
релл руны
https://mytrickstips.com/free-itunes-gift-card/?unapproved=78047&moderation-hash=a9e4744844634f9ca9852b43f0352cf3#comment-78047
https://www.texsnab.kiev.ua/blog/fiksatsiya-porushen-v-avtomatichnomu-rezhimi-abo-posmihajtes-vas-znimae-kamera
http://lasendaantigua.org/an-example-post/?unapproved=115364&moderation-hash=efd00ad607cebe7c9f221a8ba19775b8#comment-115364
http://www.blueangel.ca/operacion-terra/?unapproved=122237&moderation-hash=650d5e3f087740f8dab46ff169c75c64#comment-122237
http://ketopurediets.com/insta-keto-pills/?unapproved=2412&moderation-hash=016074da99488d75adfaa36dc9cb604b#comment-2412
свастика руны значение
ноктюрн руны
лагуз значение руны
кейтлин руны
феху руна
руна тис значение
руна турисаз значение
символы рун
значение руны одина
руны медальон значение
фиора руныруна гебославянские руны значениеv руна значениеруны std значение
руна тора
руны значение славянские
иллаой руны
руны речи
руна белобога значение
вирд руна значение
руна денежная
тату руны значение
руна чернобог
йи руны
руна сила значение
canada generic tadalafil cialis cost tadalafil online with out prescription cialis cost https://tadalafilww.com/ – cost tadalafil generic
руна валькнут значение
руны амулеты значение
руна йера значение
древние руны значение
тимо руны
https://reliablesources.blogs.cnn.com/2013/09/15/patricks-picks/comment-page-11/
http://verzijde.nl/ger-verzijde/?unapproved=428739&moderation-hash=152a6eee61b6baa07b7713b4762baa0c#comment-428739
http://roconcer.s60.xrea.com/cgi-bin/bbs/z-bbs.cgi?
https://www.ziel-vor-augen.com/component/k2/item/5-best-summer-fashion-fair-2014/
https://ph.okfn.org/2014/10/21/talk-data-to-me-an-open-data-meet-up/?unapproved=166608&moderation-hash=422f00417f627930b29b81ccb9ffcee5#comment-166608
руны здоровья
все руны
руны эко
руны дня
руна eolh значение
руны викингов значение
перевод рун
руны значение эйваз
руны петра значение
руна радость
руны арискайрим рундагаз рунаруны тиморуна тату значение
значение руны совелу
значение руны даждьбога
вышивка рун
руна москва
перто руна
руна уруз значение
руна тир значение
руны книги
руна спокойствия
руны викингов значение
памятка значения рун
tadalafil price walmart https://cttadalafil.com/ – tadalafil order online no prescription generic cialis online fast shipping where to buy tadalafil on line https://tadalafilww.com/
generic cialis online fast shipping tadalafil side effects cialis at canadian pharmacy what is tadalafil https://tadagatadalafil.com/ – cialis cost
buy avana uk avanafil cost
Hi! Someone in my Myspace group shared this website with us so I came
to give it a look. I'm definitely loving the information. I'm book-marking and will be tweeting this to my followers!
Exceptional blog and wonderful style and design.
my web site; lionking888 Ios (mega888sg.com)
https://cttadalafil.com/ cialis cost https://tadalafilol.com/ – cialis without prescription best price usa tadalafil
tadalafil cost walmart https://cttadalafil.com/ buy cialis pills where to order tadalafil tablets tadalafil daily online
avanafil dosing avanafil dosage
cost of cialis [url=https://tadalafilol.com/ ]tadalafil online [/url] generic cialis tadalafil side effects of tadalafil https://tadacipetadalafil.com/
https://tadacipetadalafil.com/ tadalafil liquid tadalafil goodrx generic tadalafil from uk tadalafil without a doctor prescription
where to buy cialis without prescription https://apcalisetadalafil.com/ – cialis at canadian pharmacy tadalafil generic where to buy buy tadalafil tadalafil drug
cheap cialis pills for sale https://tadacipetadalafil.com/ tadalafil cost in canada what is tadalafil where to order tadalafil tablets
https://tadacipetadalafil.com/ prescription tadalafil online https://tadalafilol.com/ – best price usa tadalafil buy generic cialis online with mastercard
https://cttadalafil.com/ tadalafil goodrx [url=https://tadalafilww.com/ ]where to order tadalafil tablets [/url] tadalafil without a doctor prescription
lowest price cialis https://tadagatadalafil.com/ – tadalafil side effects buy cialis pills cialis without prescription tadalafil cialis
buy combigan combigan bottle sizecombigan
руна кейтлин
йи руны
руна защиты
психологическое значение рун
кельтские руны значение
http://robertaguilar.com/2019/08/mass-shooting-in-el-paso-texas-ep-56/?unapproved=68501&moderation-hash=d2f38b94ca63fcf0296189f7c41a7f09#comment-68501
https://ipne.ws/novosti-ukrainy/rubric/gonka-politikov-kto-sobiraetsya-v-prezidenty-ukrainy/?unapproved=33546&moderation-hash=21ac8c22d49b56da82280ac7235829ff#comment-33546
https://wiki.feagri.unicamp.br/doku.php?id=fa733:crescimento_microbiano#comment_5baffc8ff167e4d65aff476b3f7d4548
https://www.docconcierge.com.br/uncategorized/mito-ou-verdade/?unapproved=287&moderation-hash=036b165003c58ec84923c27842cf16c0#comment-287
http://www.globosapiens.net/travel-advertisement.html?error=06&email=jaquelinejeffersonxl16%40gmail.com&name=Donjackkeefs&subject=94eegfdsf2df83bkslldk1&message=%3Ca+href%3Dhttps%3A%2F%2Fzootovaryvsems.site%2Fpost%2Fcat%2Bchow%2Burinary%3E%3Cimg+src%3D%22https%3A%2F%2Fic.pics.livejournal.com%2Fshalenaolena%2F21982935%2F37303%2F37303_900.jpg%22%3E%3C%2Fa%3E++++%3Ca+href%3D%22https%3A%2F%2Fzootovaryvsems.site%2Fpost%2Fcat%2Bchow%2Burinary%22%3E%3Cimg+src%3D%22https%3A%2F%2Fic.pics.livejournal.com%2Fshalenaolena%2F21982935%2F37303%2F37303_900.jpg%22+width%3D%22400%22+height%3D%22400%22+alt%3D%22%D1%80%D1%83%D0%BD%D1%8B%22%3E%3C%2Fa%3E++++++++Hi+all%21+ma+favorite+city+is+a4319+94eegfds3dslklaa83b+o283+%3Ca+href%3Dhttps%3A%2F%2Fzootovaryvsems.site%2Fpost%2Fcat%2Bchow%2Burinary%3Ehttps%3A%2F%2Fzootovaryvsems.site%2Fpost%2Fcat%2Bchow%2Burinary%3C%2Fa%3E
соло руна значение
подробное значение рун
соль руна значение
руна исток
значения руны опора
руны значение фото
значение руны волка
чувашские руны
руна достатка
перевод значения рун
руны квиннкальк рунаруна люксзначение руны турисазкраткие значения рун
все руны
руна банк
языческие руны значение
руны значения кратко
руны стихий
7 руна
значение языческих рун
значения всех рун
руны виктор
руны райз
значение руны солнце
buy cialis pills tadalafil drug best price usa tadalafil https://cttadalafil.com/
cost tadalafil generic [url=https://tadalafilww.com/ ]where to buy generic cialis online safely [/url] where to buy tadalafil on line tadalafil order online no prescription https://tadagatadalafil.com/
Hiya! Quick question that's totally off topic. Do
you know how to make your site mobile friendly? My site looks weird when browsing from my iphone.
I'm trying to find a template or plugin that might be able to correct this issue.
If you have any recommendations, please share.
With thanks!
Feel free to surf to my web blog: wukong333 demo id
https://tadacipetadalafil.com/ canada generic tadalafil cheapest tadalafil cost tadalafil cialis what is tadalafil
значение рун тату
руна смерти значение
руны солнышко
руна леля значение
недфорспид рун
https://allthingstrill-com.myshopify.com/blogs/long-live-pimp-c/ugks-super-tight-turn-25?comment=123654373510#comments
https://xnesjy.com/forum.php?mod=viewthread&tid=11230&extra=
http://www.ghtsalesinc.com/uncategorized/hello-world/#comment-6008
http://dom.encyklopedia.info/pranie-dywanow-i-tapicerki-dla-leniwych/?unapproved=168832&moderation-hash=78b595729dd1962b3e054010cfccf0d8#comment-168832
https://cateringzone.com.au/the-cheapest-food-to-cater-for-an-office-meeting/?unapproved=4523&moderation-hash=8ebf27805293ba3ecee6e398aa78f7f6#comment-4523
даждьбог руна
ур руна значение
кс рун
ведьмак руны
один руна значение
эзраэль руны
прозерпина руны
руны магии
руна москва
виктор руны
веды значение рунгерманские руны значениерасшифровка рунруны эш15 руна значение
руна ткани
thurisaz руна значение
русские руны
руна ак значение
руны иннер
свастика руны значение
руна ключ
руна алтарь значение
руна значение отношения
руны рамус
показать значение рун
https://tadalafilww.com/ side effects for tadalafil [url=https://apcalisetadalafil.com/ ]cialis without a prescription [/url] tadalafil daily online
cialis without prescription tadalafil order online no prescription where to buy cialis without prescription cialis cost https://tadalafilol.com/
https://cttadalafil.com/ best price usa tadalafil cost of cialis tadalafil without a doctor prescription tadalafil dosage
brimonidine tartrate ophthalmic buy generic brimonidine
avana 200 mg avanafil cost
tadalafil brands tadalafil goodrx tadalafil generic cialis tadalafil [url=https://tadalafilww.com/ ]tadalafil order online no prescription [/url]
generic tadalafil from uk https://tadacipetadalafil.com/ generic cialis online fast shipping generic cialis tadalafil tadalafil blood pressure
tadalafil https://tadalafilww.com/ – cialis without a prescription tadalafil dosage tadalafil price walmart https://tadalafilww.com/
tadalafil blood pressure https://tadalafilww.com/ – where to buy tadalafil on line buy generic cialis online with mastercard tadalafil online cialis at canadian pharmacy
https://tadagatadalafil.com/ tadalafil side effects [url=https://tadalafilww.com/ ]tadalafil cialis [/url] tadalafil price walmart
tadalafil brands https://tadalafilol.com/ – tadalafil cost in canada tadalafil blood pressure tadalafil order online no prescription https://tadalafilol.com/
brimonidine side effects buy generic brimonidine
combigan generic prices brimonidine how it works
buy generic cialis online with mastercard tadalafil cialis cialis without prescription cialis at canadian pharmacy https://apcalisetadalafil.com/ – best price usa tadalafil
https://tadalafilww.com/ cialis cost lowest price cialis where to buy cialis without prescription generic cialis tadalafil
buy tadalis [url=https://tadalafilww.com/ ]generic cialis online fast shipping [/url] cialis without prescription buy tadalis https://apcalisetadalafil.com/
hydroxychloroquin https://chloroquineorigin.com/# – dolquine buy chloroquine uk what is clonidine chloroquine phosphate generic name
brimonidine generic combigan
tadalafil cost in canada tadalafil cost walmart tadalafil side effects where to get tadalafil [url=https://tadalafilol.com/ ]side effects of tadalafil [/url]
tadalafil goodrx buy tadalafil tadalafil without a doctor prescription where to get tadalafil https://cttadalafil.com/
tadalafil cialis https://tadagatadalafil.com/ tadalafil order online no prescription tadalafil drug cheap generic cialis for sale
avanafil vs cialis avanafil 100
https://apcalisetadalafil.com/ cost of cialis https://tadacipetadalafil.com/ – cialis cost where to buy generic cialis online safely
combigan generic prices brimonidine dosage