 |
|
|
|
May 18th, 2011
05:05 PM ET
Stop selling higher dose Alzheimer's drug, group saysA specific dose of Alzheimer’s drug should be pulled from the market because it poses a risk to patients, according to a consumer group. The drug, donepezil, sold under the brand Aricept, is administered in several doses – the highest being 23 milligrams – for patients with moderate to severe Alzheimer’s disease. It is prescribed to improve mental function, such as memory, attention and reasoning by increasing a brain chemical. Aricept which is taken daily, could slow the mental decline, but it does not cure or prevent Alzheimer's. The Public Citizen’s Health Research Group called the 23-milligram dose of Aricept “significantly more toxic” than the 10-milligram dose and said it “should be immediately withdrawn from the market.” The group says that the drug in higher dose compared with the 10-milligrams could pose increased adverse effects such as slowed pulse rate, nausea, vomiting, diarrhea, urinary incontinence, fatigue, dizziness and agitation. The group also said the higher dose does not appear to give any benefits to the patients. Patients often stop taking the higher dose because of its strong side effects such as vomiting. And Alzheimer’s patients are particularly sensitive to vomiting because it can lead to other problems such as pneumonia, massive gastrointestinal bleeding, esophageal rupture and even death, the group said. In response, Pfizer, which co-promotes Aricept with another company, Eisai, wrote in an emailed statement: "We are reviewing the petition and will respond accordingly; however, it is important to note that the Aricept (donepezil HCl) 23 mg tablet has been approved by the U.S. Food and Drug Administration for the treatment of moderate-to-severe Alzheimer’s disease. " Dr. James Lah, director of the cognitive neurology program at Emory University"s Department of Neurology, regularly prescribes Aricept to patients, but doesn't prescribe the 23-milligram dose. “Being Americans, the notion is that bigger is better, more is better... it’s simply not true in this particular instance,” Lah said. He said he was concerned when the FDA approved the 23-milligram version. “There is very little evidence that it’s superior,” Lah, an Alzheimer's clinician and associate professor said. “There is a lot of evidence that it’s worse in terms of causing side effects. If you look at the one study, only one clinical trial reported about the 23 versus 10 milligram Aricept. The results were entirely mixed in terms of effectiveness.” soundoff (35,738 Responses)« Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 695 696 697 698 699 700 701 702 703 704 705 706 707 708 709 710 711 712 713 714 715 Next »Leave a Reply to Davidssasw
Next entry »SF to vote on male circumcision in November
« Previous entryNBA owner's son nets laughs in promoting tumor awareness
|
  About this blog
Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.
 |
|
|
|
avanafil 50 buy avanafil canada
tadalafil drug https://tadacipetadalafil.com/ tadalafil liquid lowest price cialis tadalafil liquid
https://apcalisetadalafil.com/ buy tadalis https://cttadalafil.com/ – buy cialis what is tadalafil
tadalafil drug https://tadagatadalafil.com/ – tadalafil online cialis without a prescription tadalafil cost in canada canada generic tadalafil
combigan eye drops brimonidine tartrate ophthalmic
гар руна
руна ингваз значение
значение руны райдо
руна смерти
руны треугольник значение
http://www.entiendes.eu/_n26659_el-delito-de-ser-gay-entre-beatles.html
https://www.murderinclondon.com/hello-world/?unapproved=190&moderation-hash=2543686df99ca103a58eb5bb0a6b326a#comment-190
https://banabi.com.tr/urun/coca-cola-sekersiz-sise/?unapproved=34512&moderation-hash=7a8b34c5022713a86a9af6d6549c4aa3&v=ebe021079e5a
http://www.socialdude.com/hello-world/?unapproved=68412&moderation-hash=f3efae72a4f5b2c23d1b8f8316a2065f#comment-68412
http://www.ludobjets.fr/panneau-daffichage/?unapproved=8256&moderation-hash=aaf0ccb623cb4d4da130569f95785bd6#comment-8256
руна науд
руны эш
ингваз руна
зиггс руны
белая руна
руна славянская
отал руна
лилия руны
руна треугольник значение
англосаксонские руны
юникод руныкатарина руныруна ир значениеруны значение сочетаниетатуировки руны
руны рамбл
руны ари
руна волка значение
руна славянская
руна исток значение
руна судьбы значение
руна родимич значение
топ руны
история рун
руна достатка
руна ингуз значение
avanafil 50mg avanafil dosage
https://tadalafilol.com/ buy cialis pills [url=https://tadalafilol.com/ ]buy cialis [/url] buy cialis
buy cialis https://apcalisetadalafil.com/ – tadalafil online tadalafil brands prescription tadalafil online https://tadalafilol.com/
buy avana canada buy avanafil online
https://tadagatadalafil.com/ tadalafil drug canada generic tadalafil cost of cialis side effects for tadalafil
наутиз руна значение
значение руны
венгерские руны значение
скандинавские руны значение
ингуз руна значение
http://forum.casterbrotherhood.com/viewtopic.php?f=2&t=15157&p=227663#p227663
https://travelo.com.au/a-seaside-reset-in-laguna-beach/#comment-320206
https://jcminhaiti.org/contact/?contact-form-id=4&contact-form-sent=7311&contact-form-hash=f35f363772d0314dfbec4cee0582c6f80da8dc62&_wpnonce=50eb710732
https://bushizo.shop/archives/1793?unapproved=177424&moderation-hash=152634eebfaf3a3b00d497e1c46c3997#comment-177424
http://microbion.it/en/vitafoods/?unapproved=167184&moderation-hash=374017092be515cab4eea3c3c123a622#comment-167184
руны сонник значение
проживание рун
соулу значение руны
руна ветер значение
руны вай
значение руны берегиня
урус руны значение
руны карты значение
славянские руны
значение руны асс
значение рун таблицазначения руны отиларуна опораруна ингруна дагаз значения
руны сочетание значение
руна один
алатырь руны значение
вольфсангель руна значение
руна ключ значение
значение руны феху
значения рун перт
руны варус
руна эсингер значение
руны соулу
руны ари
tadalafil liquid tadalafil dosage canada generic tadalafil https://tadalafilww.com/
where to get tadalafil https://tadagatadalafil.com/ generic cialis online fast shipping tadalafil side effects tadalafil order online no prescription
tadalafil goodrx tadalafil order online no prescription canada generic tadalafil tadalafil online with out prescription https://tadacipetadalafil.com/
avanafil buy avanafil online
cheap generic cialis for sale https://tadalafilww.com/ – side effects for tadalafil tadalafil order online no prescription tadalafil order online no prescription tadalafil order online no prescription
avanafil stendra buy avana canada
buy brimonidine combigan uk
руны вотана
кеннен руны
руна дезинформации значение
руны сеть
описание рун
https://www.rigidtactical.com/salute-to-the-10th-mountain-division/?unapproved=951&moderation-hash=658e80068c02abceacd3ee61a26e947a#comment-951
https://samorodok.com/guestbook
https://vs6-news0.blog.ss-blog.jp/2010-07-02-1?comment_success=2021-05-02T02:50:32&time=1619891432
http://sityodtongworldwide.com/portfolio-item/waterfall-1/waterfall-1-2/?unapproved=96029&moderation-hash=297ba19507c85ec22c4fe8480219c348#comment-96029
http://www.fvrc.ru/forums/index.php?topic=133669.new#new
конструктор руна
руны объединение
руна имя значение
алатырь руна
значение рун соул
значение перевернутых рун
значение руны 22
руна семаргла значение
руна ясно значение
значение знаков руны
зак руныруны вейгаркайса руныруны рейканзначение руны лагуз
руны скандинавские значения
руна стан значение
расшифровка рун
руна фото
значение ведьминых рун
руны азир
ткани руна
германские руны значение
ооо руна
руна ромб значение
зеркальные руны значение
avana tablet buy avana online
cheapest tadalafil cost https://tadagatadalafil.com/ – tadalafil online with out prescription tadalafil brands where to buy tadalafil on line generic cialis online fast shipping
https://apcalisetadalafil.com/ best price usa tadalafil https://tadalafilol.com/ – tadalafil online with out prescription tadalafil online with out prescription
buy cialis tadalafil online where to buy generic cialis online safely cheapest tadalafil cost https://tadalafilol.com/
combigan generic prices combigan bottle sizecombigan
руны арт
амулеты руны значение
показать значение рун
пв руны
таро руны
http://www.eczanemdepo.com/blog/2019/11/20/canim-askim-serap/?unapproved=52147&moderation-hash=2112ea51924a37f97a891348975b2a8b#comment-52147
http://sistemasdelta.com/hello-world/?unapproved=43337&moderation-hash=a2dc0582fdb51831573588cadd4b2f94#comment-43337
https://www.america-west.com/a-comfortable-ride-nemt-services?unapproved=24165&moderation-hash=71c28ff1e1dab08bd8bc15f6ee8b6705#comment-24165
https://baonguyena.vn/?form_type=contact&contact%5Bname%5D=DonjackAwaft&contact%5Bphone%5D=89318648355&contact%5Baddress%5D=Kampala&contact%5Bpeople%5D=&contact%5Bdate%5D=03-05-2021&contact%5Bemail%5D=jaquelinejeffersonxl16@gmail.com&contact%5Bbody%5D=Hi%20all!%20ma%20favorite%20city%20is%20a4319%2094eegfds3dslklaa83b%20z305%20https%3A%2F%2Fzootovaryvsems.site%2Fpost%2Fcat%2Bchow%2Burinary&submit=
http://www.lifepath8.com/the-first-time-i-wished-i-was-dead/?unapproved=271&moderation-hash=6515b4b97cf6aadf3d47be57313122ae#comment-271
руны старославянские значение
руны бц
пертро руна значение
руны ориана
руны мальфит
рун 15б
эвелина руны
руны когмао
значения рун славянских
значение 3х рун
лисин руныйер значение рунычернобог руна значениемагия рунруна крест значение
значение руны наутиз
руны трактовка
руны эрзя значение
синько значение рун
треба руна значение
значение руны ингуз
руна значение отношения
значение руны манназ
асс руна значение
руна гадание
вейн руны
what is tadalafil buy cialis where to buy tadalafil on line cost tadalafil generic https://tadalafilww.com/
generic cialis online fast shipping [url=https://tadacipetadalafil.com/ ]cialis cost [/url] cost tadalafil generic what is tadalafil cheap cialis pills for sale
where to buy tadalafil on line https://tadacipetadalafil.com/ – cialis without prescription tadalafil order online no prescription tadalafil generic where to buy cialis without prescription
tadalafil blood pressure cost tadalafil generic where to buy tadalafil on line prescription tadalafil online https://tadalafilol.com/
brimonidine tartrate combigan cost
tadalafil cialis https://tadalafilww.com/ – tadalafil drug generic cialis online fast shipping cialis cost https://apcalisetadalafil.com/
феху руна
руны значения карт
руны дня
руна беркана значение
руны значение сочетание
http://chriswalshart.com/uncategorized/rendering/?unapproved=129462&moderation-hash=19a0a628ac235fcd3e6b1c275a48b7ba#comment-129462
http://blackheadmuseum.com/uncategorized/hello-world/?unapproved=55126&moderation-hash=d0f586704e7d6f2df159cfedf824899b#comment-55126
http://robertaguilar.com/2019/08/mass-shooting-in-el-paso-texas-ep-56/?unapproved=68349&moderation-hash=65d8a0b3b5d6a8587898822d6f72c871#comment-68349
https://finlandpassions.com/deinfo/"https:/zootovaryvsems.site/post/cat+chow+urinary"><img
http://www.kumantech.com/blog/arduino-uno-soil-humidity-sensor-project_b0020.html
руна аниме
руны вай
руна перун
руны дня
руны славянские
хагалаз руна
руна со значением
руна зиг
мари рун
руны викинги значение
соулу значение руныруна турисаззначение древнеславянских рунджера руна значениезначение руны чернобог
руна славянская значение
значение вендских рун
значение руны турисаз
руна ру
сборка рун
руны ловушка
руна игра
руны шако
эвелин руны
руна яра значение
коловрат руна значение
generic cialis tadalafil https://tadalafilww.com/ – cialis without a prescription cialis at canadian pharmacy tadalafil cialis https://tadalafilol.com/
https://apcalisetadalafil.com/ tadalafil liquid https://apcalisetadalafil.com/ – buy cialis tadalafil price walmart
tadalafil dosage https://tadagatadalafil.com/ – tadalafil online where to buy generic cialis online safely buy tadalafil https://tadagatadalafil.com/
tadalafil liquid lowest price cialis side effects for tadalafil tadalafil online with out prescription https://tadagatadalafil.com/
tadalafil cost walmart tadalafil cost walmart cialis without a prescription tadalafil goodrx https://tadalafilol.com/
combigan uk combigan side effects
руна исцеления
руна волибир
руна x значение
денежная руна
руна хагалл
http://www.caraminholas.com/projetos/douradinho/02-de-outubro-de-2009-peixe-to/#comment-166364
https://52.78.224.240/viewtopic.php?f=4&t=35863&p=98736#p98736
https://blog.profitshare.bg/sedmichnik-po-onlayn-marketing-30/?unapproved=105668&moderation-hash=b9878ad7b99e606cd713b45a48b01142#comment-105668
https://www.mac-it.ch/forum/showthread.php?tid=809131&pid=842221#pid842221
https://ez-genius.com/%e0%b8%81%e0%b8%b2%e0%b8%a3%e0%b9%83%e0%b8%8a%e0%b9%89%e0%b8%84%e0%b8%b3%e0%b8%aa%e0%b8%b1%e0%b9%88%e0%b8%87-dcdiag/?unapproved=334&moderation-hash=e3b435bcfe514ecf6b942ae77aee054a#comment-334
джарван руны
руна тюр
руны беркана
защита руны
руна тир
руна жизни
браум руны
фиора руны
йер значение руны
руна шая
руны гаданияруна эйраalgiz руна значениезначение руны исанадпись рунами
дагаз руна значение
руна виего
руна квеорт
сс руны значение
руна моргана
руна о значение
руны википедия
значение ведьминских рун
руна люкс
руна стан
белая руна
tadalafil generic where to buy [url=https://tadagatadalafil.com/ ]tadalafil [/url] where to get tadalafil cost tadalafil generic https://tadacipetadalafil.com/
combigan eye drops generic buy combigan online
https://tadalafilww.com/ buy generic cialis online with mastercard tadalafil order online no prescription tadalafil where to order tadalafil tablets
diacount canadian pharmacy https://pharmacyken.com/ – rite aid pharmacy how many store Epivir
tadalafil cost in canada what is tadalafil cialis cost where to order tadalafil tablets https://tadalafilww.com/
значение руны отила
руна белобога значение
руна пнг
руны феху
руна ингваз
http://www.infomaverick.com/hello-world/?unapproved=69132&moderation-hash=6a4b8adbd5929a1414b3e9848dcb136c#comment-69132
http://cryptolandia.ru/kriptovalyuty/signals/kriptovaluta-zilliqa-zil-prognoz-kriptovalut-investicii-v-kriptovaluty-20-01-2020/?unapproved=7080&moderation-hash=21c744242086323246151b48fbb87286#comment-7080
http://www.mndjk100.cn/1.html#comment-42
https://www.lolaramona.com/blogs/news/have-you-ever-hacked-anything?comment=122454540377#comments
https://angelsbay.net/portfolio/mountains/?unapproved=83647&moderation-hash=38edc7a42b0bed653966effecb355b45#comment-83647
руна яра значение
руна оберег
лагуз руна
руны карелии значение
руны обои
значения руны кано
руна ирий значение
значение имени руна
руны шивана
гебо значение рун
седьмая рунатреба рунадиана руныведение руна значениезначения славянские руны
совет рун
значение всех рун
руна ветра значение
руна tiwaz значение
наутиз руна значение
читать значение рун
руны их значения
руны галио
uruz руна значение
руна здоровья
скандинавские руны значения
buy tadalis buy tadalafil lowest price cialis generic cialis tadalafil https://cttadalafil.com/
avanafil india avana 100 mg
It's remarkable for me to have a website, which is useful
for my knowledge. thanks admin
Have a look at my webpage: scr sky1388
buy cialis https://tadacipetadalafil.com/ tadalafil liquid tadalafil online with out prescription tadalafil dosage