 |
|
|
|
May 18th, 2011
05:05 PM ET
Stop selling higher dose Alzheimer's drug, group saysA specific dose of Alzheimer’s drug should be pulled from the market because it poses a risk to patients, according to a consumer group. The drug, donepezil, sold under the brand Aricept, is administered in several doses – the highest being 23 milligrams – for patients with moderate to severe Alzheimer’s disease. It is prescribed to improve mental function, such as memory, attention and reasoning by increasing a brain chemical. Aricept which is taken daily, could slow the mental decline, but it does not cure or prevent Alzheimer's. The Public Citizen’s Health Research Group called the 23-milligram dose of Aricept “significantly more toxic” than the 10-milligram dose and said it “should be immediately withdrawn from the market.” The group says that the drug in higher dose compared with the 10-milligrams could pose increased adverse effects such as slowed pulse rate, nausea, vomiting, diarrhea, urinary incontinence, fatigue, dizziness and agitation. The group also said the higher dose does not appear to give any benefits to the patients. Patients often stop taking the higher dose because of its strong side effects such as vomiting. And Alzheimer’s patients are particularly sensitive to vomiting because it can lead to other problems such as pneumonia, massive gastrointestinal bleeding, esophageal rupture and even death, the group said. In response, Pfizer, which co-promotes Aricept with another company, Eisai, wrote in an emailed statement: "We are reviewing the petition and will respond accordingly; however, it is important to note that the Aricept (donepezil HCl) 23 mg tablet has been approved by the U.S. Food and Drug Administration for the treatment of moderate-to-severe Alzheimer’s disease. " Dr. James Lah, director of the cognitive neurology program at Emory University"s Department of Neurology, regularly prescribes Aricept to patients, but doesn't prescribe the 23-milligram dose. “Being Americans, the notion is that bigger is better, more is better... it’s simply not true in this particular instance,” Lah said. He said he was concerned when the FDA approved the 23-milligram version. “There is very little evidence that it’s superior,” Lah, an Alzheimer's clinician and associate professor said. “There is a lot of evidence that it’s worse in terms of causing side effects. If you look at the one study, only one clinical trial reported about the 23 versus 10 milligram Aricept. The results were entirely mixed in terms of effectiveness.” soundoff (35,738 Responses)« Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499 500 501 502 503 504 505 506 507 508 509 510 511 512 513 514 515 516 517 518 519 520 521 522 523 524 525 526 527 528 529 530 531 532 533 534 535 536 537 538 539 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 648 649 650 651 652 653 654 655 656 657 658 659 660 661 662 663 664 665 666 667 668 669 670 671 672 673 674 675 676 677 678 679 680 681 682 683 684 685 686 687 688 689 690 691 692 693 694 695 696 697 698 699 700 701 702 703 704 705 706 707 708 709 710 711 712 713 714 715 Next »Leave a Reply to Davidssasw
Next entry »SF to vote on male circumcision in November
« Previous entryNBA owner's son nets laughs in promoting tumor awareness
|
  About this blog
Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.
 |
|
|
|
factory of chemical
https://www.tcsindustry.com/pro/103.html
order fractions printable pay for uni essays gender pay gap australia essay do my lab report
cyclosporine cost buy cyclosporine
essay question generator uc application essay help algebra 1a homework help pt essay help
combigan generic prices combigan bottle sizecombigan
low price essay writing service suny purchase application essay literature review on purchase decision primary homework help stone keep castles
buy brimonidine online combigan cost
combigan side effects combigan eye drops
outbound logistics of starbucks custom writing essays writing a service improvement report high school math homework help
Very shortly this website will be famous among all blog people, due to it's fastidious content
Feel free to surf to my blog post; xe88com (https://918kiss-m.com/)
primary homework help victorian houses buy descriptive essay essay polish service thesis wordpress help
homework help holt algebra 2 law essay writing help should i do my homework right after school 11 year old boy not doing homework
help i can do my homework service delivery protests essay buy essays online uk cheap essay writing service in australia
руны русские
значение руны
майл руны
руны победы
зиг руна
https://yournewstops.blogspot.com/2021/04/blog-post_56.html
https://hophopnews.blogspot.com/2021/05/blog-post.html
https://tarrdirtwormni.tumblr.com/
руна твич
пертро руна значение
бк руна
руна r
руна даждьбога
руна берегиня
руна алтарь значение
руны дня
релл руныофала руна значениеруна каинруна уруз значенияруны сена
руна игра
соулу руна значение
руна велес
перевернутые значения рун
руна процветание значение
перт руна
руна зиг
кенен руны
cd writing service in bangalore students and social service essay in telugu favorite food and why essay writing service university
business plan help winnipeg buy comparative essay help to write phd thesis i to do my homework at six o clock tomorrow
the help novel essay money cant buy time essay homework help canada coupon riverside county library homework help
do my accounting assignment for me benefits of doing homework essay how to buy a used car essay the odyssey homework help
cyclomune cyclosporine ophthalmic
cyclomune eye drop cyclomune 0.1% eye drops cost
essay on the importance of doing your homework importance of service learning essay statistics help for thesis order a dissertation
buy cyclosporine usa cyclosporine 100 mg
write essay customer service help with essay for scholarship biochemistry homework help eagle scout service project papers
brimonidine buy combigan
how does homework help parents help with rutgers college essay doing research paper essay about community service experience
craigslist do my homework essays about illegal immigration art history research paper topics top 10 best excuses for not doing your homework
combigan side effects brimonidine dosage
cyclomune 0.1% eye drops cost buy cyclosporine usa
essay of civil service buy comparative essay engineering mechanics statics homework help chronological order process essays
help me write my scholarship essay ap lit essay help process essay how to buy a used car pay it forward theme essay
20mg cialis http://rcialisgl.com/ – cialis promise program cialis black uk
значение руны тюр
руна косплей
руна отила значение
пластур руна
руны ведьмины значение
https://hophopnews.blogspot.com/2021/05/blog-post.html
https://bopsneeews.blogspot.com/2021/05/blog-post_16.html
https://hubsternews.blogspot.com/2021/05/blog-post.html
руны фортуна
галио руны
тейваз руна
руны значение википедия
руны значение рун
ирелия руны
значение каждой руны
алатырь руна значение
славена рунызащита рунамируны ссзначение руны роктаро руны
руна вирта значение
сколько рун
руна восстановитель
значения рун футарка
руна соул
райдо значение руны
руна nauthiz значение
руны медальон значение
custom research paper writers essay importance of customer service helping people essay automotive service technician essay
интим иркутск
essay on self help is the best help in english buy essays uk d2jsp homework help essay writing services reviews
will writing service gosport quality of service essay mcgill writing service dissertation accession or order number
loyola marymount supplement essay help essay about service to community service writer jobs near me homework help block websites
franklin library homework help best website to buy essays is there a website that will do my math homework essay writing service kijiji
квин руны
руны отзывы
чистка руны
руны сион
значение древнеславянских рун
https://bopspopss.blogspot.com/2021/05/blog-post.html
https://podlesnyiakarenlei.wordpress.com/2021/05/12/%d0%b7%d0%bd%d0%b0%d1%87%d0%b5%d0%bd%d0%b8%d0%b5-%d1%80%d1%83%d0%bd-%d0%b8-%d0%b8%d1%85-%d1%81%d0%be%d1%87%d0%b5%d1%82%d0%b0%d0%bd%d0%b8%d0%b5/
https://znacheniyerun.blogspot.com/2021/05/blog-post.html
руна wunjo значение
руны круг значение
руны победы
лостфильм рун
руна любовь
руна отилия значение
руна лаукар значение
перто руна
косплей руныветер значение рунызначение руны человекруна силарунах значение
руна лагуз
руны ведьмины значение
эз руны
значение древнеславянских рун
руны магии
рун скайрим
ур руна значение
пв руны
This blog is definitely rather handy since I'm at the moment creating an internet floral website – although I am only starting out therefore it's really fairly small, nothing like this site. Can link to a few of the posts here as they are quite. Thanks much. Zoey Olsen
http://ufotech.com.vn/members/avalgon.756297/
Having read this I thought it was very informative. I appreciate you taking the time and effort to put this article together. I once again find myself spending way to much time both reading and commenting. But so what, it was still worth it!
https://avalgon.bandcamp.com/album/avalgon
Way cool, some valid points! I appreciate you making this article available, the rest of the site is also high quality. Have a fun.
https://www.kiva.org/lender/avalgon7660
Those are yours alright! . We at least need to get these people stealing images to start blogging! They probably just did a image search and grabbed them. They look good though!
http://www.nfomedia.com/profile?uid=rJkXaiD
Way cool, some valid points! I appreciate you making this article available, the rest of the site is also high quality. Have a fun.
https://www.theodysseyonline.com/user/@roberto__hernandez
This is a topic close to my heart cheers, where are your contact details though?
https://gumroad.com/avalgon
help with advanced statistics homework essay questions for the help by kathryn stockett essay on self help is the essence of heroism ap government homework help
cv writing service dubai my essay service review doing homework in chinese parent help for homework
https://chloroquineorigin.com/ hydroxychloroquin [url=https://chloroquineorigin.com/ ]chloroquine phosphate generic [/url] raoult coronavirus
cyclosporine ophthalmic buy cyclosporine online
Having read this I thought it was very informative. I appreciate you taking the time and effort to put this article together. I once again find myself spending way to much time both reading and commenting. But so what, it was still worth it!
https://www.intensedebate.com/people/avalgonStart