Mouse study may offer hope for infertile men
March 24th, 2011
04:54 PM ET

Mouse study may offer hope for infertile men

After decades of failure, researchers have managed to create fertile sperm in a laboratory, raising hopes for infertile men.

“I think for everyone in the field, especially for the potential patients, it’s quite exciting,” says Martin Dym, a professor of biochemistry at Georgetown University School of Medicine.

Japanese scientists generated mouse sperm in a dish, which has been done before. However, in the past the manufactured sperm failed to get a female mouse pregnant. This time, when they injected the sperm into egg cells, female mice delivered a dozen live baby mice.

“The proof is in the pudding,” Dym says. “They were able to get pups.”

“Bravo,” says Pamela Madsen, founder of the American Fertility Association. “This is a fabulous breakthrough for men with no sperm, such as those with Klinefelter Syndrome, or men who’ve had testicular cancer.”

Madsen points out, however, that most infertile men don’t need fake sperm, since they often have at least a few functioning sperm.

“In the world of infertility what would really be exciting would be to do this for eggs,” said Madsen, a fertility advocate and blogger.

The researchers made the sperm by taking tissue from the testes of male mice, which contain stem cells.

The trick to making sperm capable of impregnating a female was in finding the right medium from growing the stem cells.

It’s not known when scientists would start to try to make human sperm in a lab. In the past, numerous treatments that have worked in mice have been failures in humans.

soundoff (11 Responses)
  1. Carl

    I do think it would be wonderful for for a loving family to be made, through the advancement of science, but I also can't help to wonder why God decided for certain men to not be able to reproduce. Perhaps what is best is to keep Gods plans how they were intended. Either way though God will do what's necessary to keep his plans for all of us in order & their is nothing we can do about it. (Perhaps infirtility is a way to control population growth, who knows.) just God bless & hopefully happiness will come from LOVING FAMILIES who might not have had that oppertunity without science.

    March 24, 2011 at 22:09 | Report abuse | Reply
  2. kingston

    Yeap that's just what we need making more of that guy/girl. Driving slow in the fast lane talking on the cell phone. People have kids like that little bundle of joy is going to make a differance in the world. Nope. Just being in the way. Comitting crimes, having more kids.ETC. That little bundle of joy that pops out will need bail money in the near future. There should be a law in the U.S. One kid.

    March 25, 2011 at 00:22 | Report abuse | Reply
  3. Terence

    Waste of time and effort, obviously money driven, not common sense. What men need is exactly the opposite – a cure for fertility! Some safe, unobtrusive form of birth control that can protect us against the never ending assault on us by women for making babies! Wake up people.

    March 25, 2011 at 01:32 | Report abuse | Reply
  4. Seriously?

    It's sad to see people drag religion into every facet of life. Give it a rest. I think we, as a society, have advanced enough to leave fairytales behind and use our own good sense of right and wrong. Seriously. How will we ever be anything more when we rely so heavily on this ancient text? Use your brains, I beg of you.

    March 25, 2011 at 01:48 | Report abuse | Reply
  5. Ashley

    I think it's fact by now that the creation theory is irrelevant and God has no power over why people are born the way they are born. Genetics made those men infertile.

    April 11, 2011 at 00:37 | Report abuse | Reply
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