Fighting kidney disease with diet, drugs and genetic testing
November 22nd, 2010
06:33 PM ET

Fighting kidney disease with diet, drugs and genetic testing

Eating vegetables and fruits and drinking pomegranate juice  have positive effects on kidney disease, according to two presentations at the  American Society of Nephrology's scientific meeting  in Denver Colorado.

One study placed patients with moderately reduced kidney function on a diet high in fruits and vegetables. The researchers hypothesized that the Western diet produces an acidic environment in the body that can worsen as kidney function decreases. After 30 days on the diet, the patients had reduced urine excretion of three markers that signal kidney injury: albumin, transforming growth factor, and N-acetyl-á-D- glucosaminidase. While the study by Texas A&M College of Medicine and Scott and White Healthcare was small– only 40 patients - the researchers indicated their findings merit larger and longer term studies to determine whether the dietary intervention, which is a simple and inexpensive treatment, produces the same results.

Many people have seen commercials claiming the health and antioxidant benefits of drinking pomegranate juice, which include claims that it can lower cholesterol and blood pressure in patients with diabetes and hypertension.

An Israeli study found that dialysis patients who drank pomegranate juice before dialysis treatments showed reduced inflammation and minimized oxidative stress damage from free radicals, as well as lower hospitalization rates from infections.

The small study included 101 patients who received either pomegranate juice or a placebo three times per week for a year. The researchers say their findings show that pomegranate juice has powerful antioxident properties with benefits for dialysis patients.

African Americans with kidney disease related to high blood pressure and who carry gene variant common in African Americans are 1.5 times more likely to be at risk for progressive kidney disease, researchers from Johns Hopkins University said at the scientific meeting last week.

End stage renal disease occurs when the kidneys fail or almost completely fail to properly remove waste from the body. ESRD is 13.1 times more common in African Americans compared with white subjects, according to the American Society of Nephrology.

The variant MYH9 gene was very common, present in 55 percent of the AASK (African American Study of Kidney Disease and Hypertension) study participants. Its association with progressive kidney disease was independent of age, sex, or treatment for high blood pressure. The same variants are present in many African Americans without kidney disease, however.

Knowing how specific genetic variations can effect outcomes and the progression of kidney disease "and may lead to areas of research to slow or prevent progressive kidney disease," according to Brad Astor, lead researcher from Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland.

Chronic kidney disease patients who took the cholesterol-lowering drug Vytorin had one-sixth fewer strokes, heart attacks or operations to open blocked arteries than patients who took a placebo. The results of the five-year SHARP (Study of Heart and Renal Protection) trial were presented on Saturday.

The main benefit to patients was the reduction in procedures to open blocked arteries and preventing certain types of strokes, according to lead researcher Dr. Colin Baigent of Oxford University, who presented the findings. In the group of patients treated with Vytorin, 284 had operations to unblock arteries, compared with 352 patients in the placebo group, which was statistically significant. Baigent explained that while the 9,000 patient study was large, it did not include enough patients to show differences in heart attacks and coronary deaths.

A press release from Merck, maker of Vytorin, noted, "This is the first prospective clinical study in patients with chronic kidney disease to demonstrate the benefit of lowering LDL (bad) cholesterol on major vascular events."
Vytorin is a combination of cholesterol fighters ezetimibe (Zetia) and simvastatin (Zocor), that is used for treating high levels of cholesterol in the blood.

soundoff (233 Responses)
  1. Datacenter Proxies For Sale

    Real clear internet site, regards for this post.


    February 15, 2021 at 10:47 | Report abuse | Reply
  2. KvaxMile

    indian bank cash credit loan maybank amex cash advance cash advance america cedar park

    February 16, 2021 at 02:28 | Report abuse | Reply
  3. FbsgZisse

    cialis in vegas indian cialis cialis super active experiences

    February 16, 2021 at 22:51 | Report abuse | Reply
  4. NbnhZisse

    sildenafil no prescription http://vigedon.com/ 30 mg viagra

    February 17, 2021 at 02:17 | Report abuse | Reply
  5. FqbbEncox

    payday loans no bank account killeen tx payday loans mississauga online cash converters loan rates

    February 17, 2021 at 03:46 | Report abuse | Reply
  6. ClarkTauts

    4nqla 9p8rb j7bn

    February 28, 2021 at 12:21 | Report abuse | Reply
  7. Abram Argentieri

    Good day! Do you use Twitter? I'd like to follow you if that would be okay. I'm definitely enjoying your blog and look forward to new updates.


    March 1, 2021 at 20:35 | Report abuse | Reply
  8. ClarkTauts

    kr0vg m58ek savm

    March 1, 2021 at 23:30 | Report abuse | Reply
  9. KndnMile

    viagra versus cialis viagra and nitrates viagra coupons

    March 2, 2021 at 02:56 | Report abuse | Reply
  10. FjjuZisse

    how does viagra work woman viagra female viagra pills

    March 3, 2021 at 09:46 | Report abuse | Reply
  11. NbmoZisse

    cialis, generic http://buycialisxz.com/ overnight pharmacy 4 u cialis

    March 3, 2021 at 14:17 | Report abuse | Reply
  12. AbgcEncox

    https://thesiswritingtob.com/ – thesis in writing phd thesis help good thesis statement thesis writing online

    March 23, 2021 at 00:14 | Report abuse | Reply
  13. JvqqEncox

    https://dissertationahelp.com/ – mba dissertation dissertation online dissertation writing assistance best dissertations

    March 24, 2021 at 01:16 | Report abuse | Reply
  14. GrvCrulk

    https://kloviagrli.com/ – viagra canadian pharmacy ezzz https://vigedon.com/ – viagra bottle https://llecialisjaw.com/ – is cialis over the counter https://jwcialislrt.com/ – what does cialis look like https://jecialisbn.com/ – how long does it take for cialis to work

    March 25, 2021 at 09:44 | Report abuse | Reply
  15. AbgcEncox

    https://thesiswritingtob.com/ – thesis for dummies business thesis topics phd no thesis thesis literature review

    March 25, 2021 at 19:58 | Report abuse | Reply
  16. LmoppEncox

    http://essaywriteris.com/ – write my essay paper write my admission essay order cheap essay online cheap essay online

    March 25, 2021 at 21:53 | Report abuse | Reply
  17. BrfgMile

    https://ljcialishe.com/ – cialis for women https://cialisvja.com/ – what does cialis look like https://viagraonlinejc.com/ – goodrx viagra https://viagratx.com/ – can you buy viagra over the counter https://buycialisxz.com/ – cheapest cialis

    March 30, 2021 at 19:45 | Report abuse | Reply
  18. AbgcEncox

    https://thesiswritingtob.com/ – help in thesis writing help thesis proposal for thesis writing the thesis

    March 30, 2021 at 23:47 | Report abuse | Reply
  19. AbgcEncox

    https://thesiswritingtob.com/ – thesiswritingtob.com thesis writing service thesiswritingtob.com phd thesis proposal

    April 7, 2021 at 17:05 | Report abuse | Reply
  20. FbsfEncox

    global pharmacy canada https://uspharmus.com/ Maxalt

    April 22, 2021 at 19:25 | Report abuse | Reply
  21. BbdfMile

    viagra without a doctor prescription canada https://gensitecil.com/ what is the shelf life of viagra

    April 23, 2021 at 03:47 | Report abuse | Reply
  22. LhdvZisse

    viagra and cialis https://asciled.com/ – find cheapest cialis pills research cialis

    April 23, 2021 at 18:08 | Report abuse | Reply
  23. JbsdEncox

    Malegra FXT viagra professional top rated canadian pharmacies online

    April 24, 2021 at 02:43 | Report abuse | Reply
  24. GvdbCrulk

    tadalafil 5 mg generic http://boxtadafil.com/ tadalafil dose

    April 25, 2021 at 12:13 | Report abuse | Reply
  25. JbsdEncox

    Epivir http://onlinecanda21.com/ canadian pharmacy online viagra

    April 26, 2021 at 06:10 | Report abuse | Reply
  26. RfvbZisse

    cheap cialis with dapoxetine https://cileve.com/ – generic cialis best price cialis supper active

    April 26, 2021 at 13:57 | Report abuse | Reply
  27. LhdvZisse

    cialis deliver next day http://asciled.com/ cialis super active vs professional

    April 26, 2021 at 15:39 | Report abuse | Reply
  28. LrbsEncox

    levitra vs cialis vs viagra reviews http://uslevitraanna.com/ viagra vs levitra reviews

    April 26, 2021 at 16:37 | Report abuse | Reply
  29. GvdbCrulk

    online prescription tadalafil https://boxtadafil.com/ best generic tadalafil

    April 27, 2021 at 17:05 | Report abuse | Reply
  30. AbdgEncox

    Requip http://canadianeve21.com/ – Dostinex Plendil

    April 27, 2021 at 18:06 | Report abuse | Reply
  31. BbdfMile

    coupons for viagra http://gensitecil.com/ diabetes and viagra

    April 27, 2021 at 19:22 | Report abuse | Reply
  32. RfvbZisse

    cialis 10mg https://cileve.com/ canadian pharmacy for cialis for sale

    April 27, 2021 at 19:53 | Report abuse | Reply
  33. FbsfEncox

    canadian pharmacy viagra brand https://uspharmus.com/ – Tadalis SX medicine online shopping

    April 28, 2021 at 02:29 | Report abuse | Reply
  34. LrbsEncox

    levitra generic brand http://uslevitraanna.com/ hearing levitra

    April 28, 2021 at 17:29 | Report abuse | Reply
  35. LhdvZisse

    viagra cialis from germany https://asciled.com/ geneneric cialis aus

    April 30, 2021 at 08:05 | Report abuse | Reply
  36. FbsfEncox

    Dostinex http://uspharmus.com/ Flexeril

    April 30, 2021 at 13:45 | Report abuse | Reply
  37. BbdfMile

    viagra and cocaine https://gensitecil.com/ viagra and weed

    May 2, 2021 at 22:40 | Report abuse | Reply
  38. FmrfEncox

    cialis pricing http://cialisee.com/ cialis discussion forum

    May 3, 2021 at 13:22 | Report abuse | Reply
  39. Puppy supplies

    Hey I know this is off topic but I was wondering if you knew of
    any widgets I could add to my blog that automatically tweet my newest twitter updates.
    I've been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this.
    Please let me know if you run into anything. I truly enjoy reading
    your blog and I look forward to your new updates.

    May 3, 2021 at 13:22 | Report abuse | Reply
  40. BbshMile

    cost of viagra http://loxviagra.com/ viagra 100mg price per pill

    May 3, 2021 at 21:21 | Report abuse | Reply
  41. LbsoZisse

    generic cialis 20mg http://ucialisdas.com/ buy cialis toronto

    May 4, 2021 at 16:57 | Report abuse | Reply
  42. JebgEncox

    canada pharmacies online http://pharmacylo.com/ canadian pharmacy discount coupon

    May 4, 2021 at 20:20 | Report abuse | Reply
  43. GtnbCrulk

    viagra woman http://jokviagra.com/ – online viagra prescription viagra and cialis

    May 5, 2021 at 14:36 | Report abuse | Reply
  44. AnooEncox

    viagra what is it wikipedia http://llviagra.com/ – vrai site viagra viagra doses recommended

    May 6, 2021 at 20:17 | Report abuse | Reply
  45. JebgEncox

    Cardura http://pharmacylo.com/ Allopurinol

    May 7, 2021 at 10:41 | Report abuse | Reply
  46. GtnbCrulk

    viagra with alcohol http://jokviagra.com/ – what was viagra originally used for active ingredient in viagra

    May 7, 2021 at 10:45 | Report abuse | Reply
  47. BbshMile

    what do viagra pills look like https://loxviagra.com/ viagra triangle chicago

    May 7, 2021 at 12:36 | Report abuse | Reply
  48. RebfZisse

    windsor, ontario, canada pharmacy cialis http://rcialisgl.com/ buy dapoxetine with cialis

    May 7, 2021 at 18:27 | Report abuse | Reply
  49. LbsoZisse

    discount cialis https://ucialisdas.com/ buy cialis india

    May 7, 2021 at 19:23 | Report abuse | Reply
  50. LebnEncox

    silkroad online pharmacy http://xlnpharmacy.com/ viagra pharmacy 100mg

    May 7, 2021 at 22:08 | Report abuse | Reply
1 2 3 4 5

Leave a Reply to welding courses


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.

November 2010
  • An error has occurred, which probably means the feed is down. Try again later.