home
RSS
Fighting kidney disease with diet, drugs and genetic testing
November 22nd, 2010
06:33 PM ET

Fighting kidney disease with diet, drugs and genetic testing

Eating vegetables and fruits and drinking pomegranate juice  have positive effects on kidney disease, according to two presentations at the  American Society of Nephrology's scientific meeting  in Denver Colorado.

One study placed patients with moderately reduced kidney function on a diet high in fruits and vegetables. The researchers hypothesized that the Western diet produces an acidic environment in the body that can worsen as kidney function decreases. After 30 days on the diet, the patients had reduced urine excretion of three markers that signal kidney injury: albumin, transforming growth factor, and N-acetyl-á-D- glucosaminidase. While the study by Texas A&M College of Medicine and Scott and White Healthcare was small– only 40 patients - the researchers indicated their findings merit larger and longer term studies to determine whether the dietary intervention, which is a simple and inexpensive treatment, produces the same results.

Many people have seen commercials claiming the health and antioxidant benefits of drinking pomegranate juice, which include claims that it can lower cholesterol and blood pressure in patients with diabetes and hypertension.

An Israeli study found that dialysis patients who drank pomegranate juice before dialysis treatments showed reduced inflammation and minimized oxidative stress damage from free radicals, as well as lower hospitalization rates from infections.

The small study included 101 patients who received either pomegranate juice or a placebo three times per week for a year. The researchers say their findings show that pomegranate juice has powerful antioxident properties with benefits for dialysis patients.

African Americans with kidney disease related to high blood pressure and who carry gene variant common in African Americans are 1.5 times more likely to be at risk for progressive kidney disease, researchers from Johns Hopkins University said at the scientific meeting last week.

End stage renal disease occurs when the kidneys fail or almost completely fail to properly remove waste from the body. ESRD is 13.1 times more common in African Americans compared with white subjects, according to the American Society of Nephrology.

The variant MYH9 gene was very common, present in 55 percent of the AASK (African American Study of Kidney Disease and Hypertension) study participants. Its association with progressive kidney disease was independent of age, sex, or treatment for high blood pressure. The same variants are present in many African Americans without kidney disease, however.

Knowing how specific genetic variations can effect outcomes and the progression of kidney disease "and may lead to areas of research to slow or prevent progressive kidney disease," according to Brad Astor, lead researcher from Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland.

Chronic kidney disease patients who took the cholesterol-lowering drug Vytorin had one-sixth fewer strokes, heart attacks or operations to open blocked arteries than patients who took a placebo. The results of the five-year SHARP (Study of Heart and Renal Protection) trial were presented on Saturday.

The main benefit to patients was the reduction in procedures to open blocked arteries and preventing certain types of strokes, according to lead researcher Dr. Colin Baigent of Oxford University, who presented the findings. In the group of patients treated with Vytorin, 284 had operations to unblock arteries, compared with 352 patients in the placebo group, which was statistically significant. Baigent explained that while the 9,000 patient study was large, it did not include enough patients to show differences in heart attacks and coronary deaths.

A press release from Merck, maker of Vytorin, noted, "This is the first prospective clinical study in patients with chronic kidney disease to demonstrate the benefit of lowering LDL (bad) cholesterol on major vascular events."
Vytorin is a combination of cholesterol fighters ezetimibe (Zetia) and simvastatin (Zocor), that is used for treating high levels of cholesterol in the blood.


soundoff (71 Responses)
  1. Isabella Bobby

    I am cured from herpes with his herbal Med! I feel so much happy for being so empathetic and helpful to me, ! His website is (( https://robinbuckler. com )) or (( robinsonbuckler11 @gmail. com )) ...He restored my relationship with his love spell

    DIABETES,

    URINARY TRACT INFECTION,

    ERECTILE DYSFUNCTION/INFERTILITY

    SIMPLEX HERPES AND GENITAL,,..

    COLD SORE

    January 11, 2021 at 15:20 | Report abuse | Reply
  2. JlloCrulk

    approved canadian online pharmacies canadian pharmacies family pharmacy

    January 12, 2021 at 19:33 | Report abuse | Reply
  3. JtmfEncox

    pharmacy orlando best canadian online pharmacy the pharmacy

    January 13, 2021 at 04:13 | Report abuse | Reply
  4. NlbxZisse

    generic viagra buy viagra in south africa quick ship viagra viagra dosage mg super force viagra viagra super active plus 365 pill viagra how to get prescribed viagra cheapest viagra viagra with out prescription viagra on line australia pfizer viagra 100mg price when does viagra patent expire viagra professional super trial pack viagra levitra

    January 13, 2021 at 13:47 | Report abuse | Reply
  5. JvcxCrulk

    generic viagra price buy viagra discover card how to get viagra sydney cost of viagra at walmart viagra online stores viagra cheap overnight shippimg order viagra online order viagra online without a prescription brand name viagra buy viagra pharmacy paypal viagra canada no prescription viagra for women in hyderabad viagra per nachname bestellen best generic viagra viagra prescription filled online

    January 16, 2021 at 19:27 | Report abuse | Reply
  6. FgnhZisse

    buy viagra south africa online australia cheap viagra viagra nz viagra overnite shipping viagra sample but viagra online viagra canada where can i purchase viagra with paypal? how do i get viagra in australia can you take prozac and viagra viagra in sydney nsw what doctor prescribes viagra viagra on line paying with paypal köpa viagra paypal vviagra sample

    January 17, 2021 at 18:39 | Report abuse | Reply
  7. LcxEncox

    viagra made in india after market viagra buy viagra online with free delivery http://genqpviag.com/ – price for viagra ’

    January 18, 2021 at 13:59 | Report abuse | Reply
  8. NlbxZisse

    cialis daily use cheap cialis tablets cialis price comparison http://cialijomen.com/ – buy brand cialis 20 mg ’

    January 18, 2021 at 14:27 | Report abuse | Reply
  9. JvcbxCrulk

    buy cialis 20 mg online buy cialis uk no prescription howard stern commercial cialis http://phrcialiled.com/ – cialis tablets ’

    January 21, 2021 at 17:14 | Report abuse | Reply
  10. AqbvEncox

    were can you buy kamagra and viagra in ireland how to take viagra viagra generic 100mg http://acialaarx.com/ – paypal for viagra ’

    January 22, 2021 at 08:00 | Report abuse | Reply
  11. FbdhZisse

    acs cialis cialis 80 cialis in us http://21cialismen.com/ – cialis pills canada ’

    January 22, 2021 at 18:15 | Report abuse | Reply
  12. JbdcEncox

    cheap generic viagra free brand viagra viagra in ukВ  http://llviabest.com/ – 100mg viagra for sale ’

    January 22, 2021 at 19:45 | Report abuse | Reply
  13. KbctMile

    cialis and no prescription brand name cialis cialis http://mycialedst.com/ – cialis ’

    January 23, 2021 at 04:40 | Report abuse | Reply
  14. NmilZisse

    viagra order viagra and mastercard generic soft viagra http://xz-pharmacyonline.com/en/career-opportunities.html – buy viagra by paypal ’

    January 23, 2021 at 10:23 | Report abuse | Reply
  15. JnhCrulk

    order cialis grapefruit juice and cialis does the va approve cialis for patients http://loncialis.com/ – cialis without prescription ’

    January 26, 2021 at 01:13 | Report abuse | Reply
  16. AhmdEncox

    cialis professionel cialis&dapoxetine cheap cialis http://cialmenshoprx.com/ – cialis generic 10 mg ’

    January 27, 2021 at 02:45 | Report abuse | Reply
  17. FmfvEncox

    cialis black box warning cialis generic cialis 40 mg http://sjcialis.com/ – fed ex overnight delivery cialis ’

    January 27, 2021 at 04:04 | Report abuse | Reply
  18. KbbtMile

    best price cialis 20mg Avodart cialis online canada https://xz-pharmacyonline.com – navarro pharmacy miami ’

    January 27, 2021 at 13:36 | Report abuse | Reply
  19. FbgZisse

    viagra jelly sachet viagra cheap viagra order https://canadianpharmacy-usx.com/organic.htm – viagra 100 mg generic ’

    January 27, 2021 at 14:39 | Report abuse | Reply
  20. Sharron Lowrie

    Social network traffic Facebook likes Twitter Followers Instagram Followers and much more

    https://bit.ly/2Hnl7vE

    January 28, 2021 at 00:52 | Report abuse | Reply
1 2

Leave a Reply to Richard Finckle


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.