home
RSS
October 28th, 2010
03:21 PM ET

How serious is selective IgA deficiency?

As a feature of CNNhealth.com, our team of expert doctors will answer readers' questions. Here's a question for Dr. Gupta.

From Indu, Waukesha, Wisconsin

"My 3-year-old daughter has been diagnosed with selective IgA deficiency. I am really worried. Can you please tell me what is this? What are her risk factors and will she live a normal life? Since three months she has had recurrent sinusitis infections and her blood test showed this deficiency ( IgA =6), No one in our family has this and both my husband and I are quite healthy. What are her options, treatment and any latest information/research in this field?"

Answer

Indu, Thank you for your question. I know, as a parent, that it can be scary when the doctor tells you that something isn’t quite normal with your child, and you want to understand what may be wrong.

The immune system protects us from harmful substances—called antigens—which include bacteria, viruses, toxins, fungus, cancer cells, and allergens. When the body senses the presence of an antigen, it fights it with antibodies, which attach to the foreign substance and help the immune system to destroy them. When the immune system doesn’t produce enough antibodies to fight the antigens it’s called an immunodeficiency disorder.

You indicated that your daughter has experienced recurrent sinus infections since she was 3 months old, which is probably why her physician tested her immunity levels —to find out why she might not be fighting off her recurring  infections. The immunoglobulin test is a tool that medical professionals can use to help diagnose when the immune system isn’t working properly. People can be born with immunodeficiencies or acquire them through illness or as a side effect of medications. When a child has frequent or unusual infections, doctors may suspect an immunodeficiency.

Our bodies produce five types of antibodies including IgA, which is found in mucous membranes, IgG which is found in all body fluids and fights bacterial and viral infections, IgM, found in blood and lymph fluid and is the first line of defense fighting new infections, IgE, which fights allergic reactions, and IgD which is found in the blood and whose function is still uncertain to immunologists. IgA, IgG and IgM are often measured together because they can give useful information about how the immune system is functioning toward infection or autoimmune diseases.

Selective deficiency of IgA is the most common immune disorder and is less harmful than other disorders, according to information from the National Institutes of Health. People with this condition have low or deficient levels of immunoglobulin A, the antibody that protects the body and is found in high concentrations in mucous membranes in the respiratory passages, gastrointestinal tract, as well as in tears and saliva.

Emory University pediatric allergist Dr. Karen DeMuth said “I would never diagnose a child that age with selective deficiency of IgA,” explaining that more information is needed about her case, and adding that children's immune systems are not fully developed at her age. DeMuth strongly advises that your daughter have a consultation with an immunologist, and she notes that the American Academy of Allergy, Asthma and Immunology is an excellent resource for finding a specialist, as well as for information.

While no specific treatment is available for selective deficiency of IgA, it’s important to treat any bacterial infections with antibiotics to prevent them from recurring. If a specialist agrees that your daughter has the disorder, it’s important to know that sometimes this condition will disappear without treatment, and your medical professional is likely to recommend retesting your daughter to see if the deficiency resolves over time.


soundoff (1,376 Responses)
  1. esurance near me

    I could not resist commenting. Perfectly written!

    http://wtk.db.com/777554543598768/optout?redirect=https://ocrvcenter.co/rv-generator-repair-near-me

    May 13, 2021 at 02:07 | Report abuse | Reply
  2. best rv repair near me

    http://www.epb.dl.gov.cn/outlink/law.aspx?url=https://ocrvmotorsports.com/business-vehicle-collision-repair-shop-near-me

    May 13, 2021 at 02:24 | Report abuse | Reply
  3. RV Countertops California

    I could not refrain from commenting. Well written!

    https://dataplus.ru/bitrix/rk.php?goto=https://g.page/ocrvcenter

    May 13, 2021 at 02:48 | Report abuse | Reply
  4. couches orange county

    This is the perfect web site for anyone who would like to understand this topic. You realize a whole lot its almost hard to argue with you (not that I personally will need to…HaHa). You definitely put a brand new spin on a subject that's been discussed for many years. Great stuff, just great!

    https://www.capital.gr/viewswitcher/switchview?mobile=False&returnUrl=https://ocrv.us/city-bus-collision-repair-shop-near-me

    May 13, 2021 at 03:15 | Report abuse | Reply
  5. RV Cabinet Near Me

    http://www.harbor-gateway.com/__media__/js/netsoltrademark.php?d=www.yelp.com/biz/ocrv-center-anaheim-2

    May 13, 2021 at 04:55 | Report abuse | Reply
  6. paint repair near me

    https://www.docin.com/jsp_cn/mobile/tip/android_v1.jsp?forward=https://youtube.com/watch?v=aMf59t3yH14

    May 13, 2021 at 05:13 | Report abuse | Reply
  7. Art Van Repair

    There is certainly a lot to learn about this topic. I really like all of the points you've made.

    https://businesscatalyst.com/Redirect.aspx?destination=https://sprintervanrepairshop.com/rv-restoration-shop-near-me

    May 13, 2021 at 05:31 | Report abuse | Reply
  8. motorhomes for sale in orange county ca

    https://clixgalore.com/NoRedirect.aspx?ID=11387&AfID=225385&BID=111815&ER=1&RU=https://ocrv.us/rv-repair-shop-studio-city-california

    May 13, 2021 at 05:55 | Report abuse | Reply
  9. Gmc Safari Van Repair

    Very good info. Lucky me I recently found your blog by chance (stumbleupon). I have saved it for later!

    https://www.coloradoballet.org/Redirect.aspx?destination=https://commercialrepairshop.com/cargo-van-conversion-shop-near-me

    May 13, 2021 at 06:20 | Report abuse | Reply
  10. Mercedes Sprinter Repair Near Me

    https://www.bad.org.uk/for-the-public/patient-information-leaflets/androgenetic-alopecia/?showmore=1&returnlink=https://sprintervanrepairshop.com/high-top-van-repair-shop-near-me

    May 13, 2021 at 07:36 | Report abuse | Reply
  11. RV Frame Riverside

    I’m impressed, I have to admit. Rarely do I encounter a blog that’s both educative and engaging, and without a doubt, you have hit the nail on the head. The problem is something which not enough people are speaking intelligently about. I am very happy I stumbled across this in my hunt for something relating to this.

    http://www.sarasotakim.com/__media__/js/netsoltrademark.php?d=youtube.com/channel/UChUH5GdtSzHx6V02C90mnfQ/videos

    May 13, 2021 at 07:55 | Report abuse | Reply
  12. RV Beds Los Angeles

    https://www.myvest.info/__media__/js/netsoltrademark.php?d=goo.gl/maps/iCzoZ1dDPjhG6Dsh6

    May 13, 2021 at 09:48 | Report abuse | Reply
  13. RV Mechanics Near Me

    http://www.m2m2.ru/extlink.php?url=instagram.com/ocrvcenter

    May 13, 2021 at 11:02 | Report abuse | Reply
  14. windshield repair orange ca

    Very nice write-up. I definitely love this site. Keep it up!

    https://cutephp.com/forum/redirect/?q=https://ocrv.art/shuttle-truck-collision-repair-shop-near-me

    May 13, 2021 at 15:47 | Report abuse | Reply
  15. Mercedes Benz Sprinter Repair Shops Near Me

    Saved as a favorite, I love your website!

    http://services.nfpa.org/Authentication/GetSSOSession.aspx?return=https://commercialvanrepairshop.com/touring-van-repair-shop-near-me

    May 13, 2021 at 16:37 | Report abuse | Reply
  16. ambulance companies in orange county

    https://intranet.secure.griffith.edu.au/s/redirect?rank=10&collection=on-campus-search&url=https://ocrvcenter.biz/rv-photos

    May 13, 2021 at 19:36 | Report abuse | Reply
  17. toy hauler remodel

    I needed to thank you for this fantastic read!! I absolutely enjoyed every little bit of it. I have got you saved as a favorite to look at new stuff you post…

    http://www.lecake.com/stat/goto.php?url=http://youtube.com/watch?v=7YTIV3lgM1I

    May 13, 2021 at 20:09 | Report abuse | Reply
  18. rv tire shop near me

    Hello there, There's no doubt that your website may be having internet browser compatibility issues. When I look at your web site in Safari, it looks fine however, if opening in IE, it has some overlapping issues. I just wanted to provide you with a quick heads up! Apart from that, wonderful blog!

    https://rsv.nta.co.jp/affiliate/set/af100101.aspx?site_id=66108024&redi_url=https://ocrvcenter.net/toy-hauler-trailer-collision-repair-shop-near-me

    May 13, 2021 at 20:18 | Report abuse | Reply
  19. camper repair service near me

    https://www.sunzu.com/link/?url=https://ocrvcenter.biz/class-a-collision-repair-shop-near-me

    May 13, 2021 at 21:18 | Report abuse | Reply
  20. upholstery orange county

    https://www.bad.org.uk/for-the-public/patient-information-leaflets/androgenetic-alopecia/?showmore=1&returnlink=https://ocrvmotorsports.com/motorhome-toilet-repair-near-me

    May 13, 2021 at 21:54 | Report abuse | Reply
  21. RebfZisse

    free cialis online http://rcialisgl.com/ cialis without persciction

    May 13, 2021 at 22:44 | Report abuse | Reply
  22. truck shop orange california

    https://advocacy.socialpubli.com/site/redirect?url=https://youtube.com/watch?v=CeCBuXkUcv8

    May 14, 2021 at 02:58 | Report abuse | Reply
  23. RV Wraps Riverside

    https://gatherblogs.com/__media__/js/netsoltrademark.php?d=yelp.com/biz/ocrv-center-yorba-linda-2

    May 14, 2021 at 03:30 | Report abuse | Reply
  24. toy hauler furniture

    https://mitsui-shopping-park.com/lalaport/ebina/redirect.html?url=http://youtube.com/watch?v=lW5dKJYF3eM

    May 14, 2021 at 07:17 | Report abuse | Reply
  25. box truck roof repair

    Hello there! This blog post couldn’t be written much better! Reading through this post reminds me of my previous roommate! He always kept talking about this. I most certainly will send this post to him. Pretty sure he'll have a good read. Thanks for sharing!

    https://trackings.oxfamintermon.org/click.php?campanya=SYD1612_S0310_03126_0001&data_enviament=20161207&desti=https://ocrv.info/rv-repair-shop-culver-city-california

    May 14, 2021 at 07:48 | Report abuse | Reply
  26. Rv Mercedes Sprinter Service Center Near Me

    http://www.joomla-code.ru/go.php?gogo=https://commercialvanrepairshop.com/box-truck-windshield-replacement-shop-near-me

    May 14, 2021 at 07:48 | Report abuse | Reply
  27. Mercedes Benz Sprinter Service Center Near Me

    Howdy! This blog post could not be written any better! Going through this article reminds me of my previous roommate! He constantly kept preaching about this. I am going to send this information to him. Fairly certain he will have a great read. Thanks for sharing!

    http://delawarecpf.com/__media__/js/netsoltrademark.php?d=commercialvanrepairshop.com/frame-repair-shop-near-me

    May 14, 2021 at 08:12 | Report abuse | Reply
  28. oc towing company

    This excellent website certainly has all of the information I wanted about this subject and didn’t know who to ask.

    https://bibliopam.ec-lyon.fr/fork?https://

    May 14, 2021 at 09:35 | Report abuse | Reply
  29. 2009 Stuck Intake Dodge Sprinter Repair

    https://www.sunzu.com/link/?url=https://fleettruckrepairshop.com/sprinter-van-restoration-shop-near-me

    May 14, 2021 at 10:30 | Report abuse | Reply
  30. reupholstery services near me

    https://www.vans.com/webapp/wcs/stores/servlet/LinkShareGateway?siteID=IFCTyuu33gI-HmTv1Co9oM2RT1QCkYxD_Q&source=LSA&storeId=10153&url=https://ocrvandtrucks.com/rv-repair-shop-winnetka-california

    May 14, 2021 at 10:48 | Report abuse | Reply
  31. tv repair orange county

    Spot on with this write-up, I seriously believe that this amazing site needs much more attention. I’ll probably be back again to see more, thanks for the info!

    http://www.bioscience.org/2017/v9s/af/474/fulltext.php?bframe=https://ocrvluxurycoaches.com/rv-repair-shop-twentynine-palms-california

    May 14, 2021 at 11:36 | Report abuse | Reply
  32. rv decal repair

    Having read this I believed it was extremely enlightening. I appreciate you spending some time and energy to put this informative article together. I once again find myself spending a lot of time both reading and leaving comments. But so what, it was still worthwhile!

    https://cutephp.com/forum/redirect/?q=https://ocrvmotorsports.com/motorhome-collision-repair-shop-near-me

    May 14, 2021 at 12:33 | Report abuse | Reply
  33. school bus windshield replacement

    This website was... how do you say it? Relevant!! Finally I have found something that helped me. Appreciate it!

    http://sitebox.mailus.ru/requestform.php?success=1&referrer=https://ocrvmotorcoaches.com/rv-repair-shop-south-pasadena-california

    May 14, 2021 at 12:54 | Report abuse | Reply
  34. RV Blinds Orange County

    http://sensibleendowment.com/go.php/211/?url=http://youtube.com/channel/UCCWA5o3d2u11KvEjA3wLVUA/videos

    May 14, 2021 at 12:55 | Report abuse | Reply
  35. rv repair san diego

    Your style is really unique compared to other folks I've read stuff from. Thank you for posting when you have the opportunity, Guess I will just bookmark this blog.

    http://texasbedandbreakfast-com.securec55.ezhostingserver.com/hit.cfm?InnID=1&website=https://ocrvcenter.co/shuttle-bus-collision-repair-shop-near-me

    May 14, 2021 at 14:03 | Report abuse | Reply
  36. Eye Care Center Near Me

    http://cdn.embedded.com/common/jumplink.php?target=arizonasvision.com

    May 14, 2021 at 16:31 | Report abuse | Reply
  37. 2018 Maserati Granturismo Msrp

    Having read this I thought it was really informative. I appreciate you taking the time and energy to put this article together. I once again find myself personally spending a significant amount of time both reading and leaving comments. But so what, it was still worth it!

    http://balder.messe.de/werbung/www/delivery/ck.php?ct=1&oaparams=2__bannerid=1512__zoneid=697__cb=18dc65fbad__oadest=https://club-maserati.com/

    May 14, 2021 at 18:23 | Report abuse | Reply
  38. homes for sale near by

    I used to be able to find good advice from your blog posts.

    http://www.boosterblog.es/votar-12428-11629.html?adresse=meganleary.com

    May 14, 2021 at 20:00 | Report abuse | Reply
  39. Maserati 4200Gt

    https://www.atype.jp/track/click.php?aid=1663&linkid=b9&redirect=https://club-maserati.com/

    May 14, 2021 at 20:18 | Report abuse | Reply
  40. Eyeglasses Near Me

    After checking out a few of the articles on your site, I seriously appreciate your technique of blogging. I bookmarked it to my bookmark website list and will be checking back in the near future. Please visit my website as well and tell me what you think.

    http://t158.adsage.com/trc/track/x.gif?acc=1199&iid=p.110386427000355007.k.p&lpg=https://arizonasvision.com/

    May 14, 2021 at 21:54 | Report abuse | Reply
  41. Pediatric Eye Exam

    There's certainly a lot to find out about this topic. I love all the points you've made.

    http://momoantena.com/redirect?url=arizonasvision.com/

    May 14, 2021 at 22:21 | Report abuse | Reply
  42. houses for sale dalton gardens

    I’m impressed, I must say. Rarely do I encounter a blog that’s both equally educative and interesting, and without a doubt, you have hit the nail on the head. The problem is something not enough people are speaking intelligently about. Now i'm very happy that I found this during my search for something regarding this.

    http://www.sweetcotton.com/osanpo/search/rank.cgi?mode=link&id=1154&url=https://www.meganleary.com/

    May 14, 2021 at 22:28 | Report abuse | Reply
  43. homes for sale twin lakes

    Hello, I do believe your website might be having internet browser compatibility problems. Whenever I take a look at your web site in Safari, it looks fine however, when opening in IE, it has some overlapping issues. I simply wanted to provide you with a quick heads up! Apart from that, great site!

    http://client.paltalk.com/client/webapp/client/External.wmt?url=https://meganleary.com/

    May 14, 2021 at 22:47 | Report abuse | Reply
  44. Maserati Los Angeles

    http://www.mytown.ie/log_outbound.php?business=118705&type=website&url=https://club-maserati.com/

    May 14, 2021 at 23:18 | Report abuse | Reply
  45. LbsoZisse

    viagra and cialis http://ucialisdas.com/ generic vs brand name cialis

    May 14, 2021 at 23:43 | Report abuse | Reply
  46. How Much Does A Maserati Cost 2016

    https://secure.tickmill.co.uk/redirect/index.php?cii=132&cis=1&lp=https://club-maserati.com/

    May 15, 2021 at 00:32 | Report abuse | Reply
  47. Ray Ban Prescription Sunglasses

    Very nice post. I absolutely love this website. Thanks!

    https://audio-iwasaki.com/ys4/rank.cgi?mode=link&id=1551&url=https://arizonasvision.com/

    May 15, 2021 at 01:07 | Report abuse | Reply
  48. real estate for sale rathdrum id

    https://as.domru.ru/go?url=http://meganleary.com/

    May 15, 2021 at 02:12 | Report abuse | Reply
  49. homes for sale spirit lake idaho

    When I originally left a comment I appear to have clicked on the -Notify me when new comments are added- checkbox and from now on each time a comment is added I recieve four emails with the exact same comment. Is there an easy method you can remove me from that service? Thanks!

    https://www.neoromance.info/link/rank.cgi?mode=link&id=26&url=https://www.meganleary.com/

    May 15, 2021 at 03:42 | Report abuse | Reply
  50. 2019 Maserati Levante Msrp

    https://www.okmedicalboard.org/external-link?url=https://club-maserati.com

    May 15, 2021 at 03:47 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28

Leave a Reply to RV Repair Nearby


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.