Smoking boosts risk for Alzheimer's
October 25th, 2010
04:52 PM ET

Smoking boosts risk for Alzheimer's

Here's yet another reason to stop smoking: It elevates the risk of Alzheimer's disease and vascular dementia, according to a new study.

An analysis of more than 20,000 men and women found a 157 percent heightened risk of Alzheimer's disease in people who had smoked more than two packs of cigarettes a day. For vascular dementia, the second most common form of dementia, these smokers had a 172 percent increased risk.

"Dementia is a disease that crops up in late life, and that becomes clinically apparent, but I think people really need to think about risk factors for it over the life course," said Rachel Whitmer, study co-author and research scientist with Kaiser Permanente Division of Research in Oakland, California.

The study, sponsored by Kaiser Permanente, is published in the Archives of Internal Medicine.

Researchers say the association between smoking and various forms of dementia is strong, but they do not know exactly why. It has been shown before that people who smoke are more likely to have hypertension and cerebral vascular disease, as well as inflammation, Whitmer said. Smoking may contribute to the damage of brain blood vessels in addition to brain cells, she said.

The data came from Kaiser Permanente Northern California members surveyed between 1978 and 1985. At that time, they were between ages 50 and 60. Diagnoses of various forms of dementia among these people were made from 1994 to 2008, and researchers took that information from electronic health records. The participants in this study were all alive and still members of the health plan in 1994.

Researchers found that associations with the development of the disease are more modest among smokers who use up fewer than two packs a day, but still significant. Those who smoked a half-pack to one pack a day had an overall 37 percent elevated risk of dementia, and those who smoked between one and two packs had a 44 percent heightened risk, compared to non-smokers.

But this could be an underestimation, because some smokers who would have developed dementia died before diagnosis, said Kenneth Hepburn, associate dean for research at the Emory University School of Nursing, who was not involved in the study.

The reported risk of dementia among heavy smokers is also likely an underestimation because many of those people will die before they're old enough to develop dementia, he said.

While the elevated risk for various forms of dementia was shown for those smoking two packs a day in midlife, smoking less than half a pack of cigarettes a day, or having smoked in the past, did not appear to raise the risk compared with nonsmokers.

Hepburn found the study compelling, and noted that it incorporated an ethnically diverse population of both men and women.

"This gives great confidence in saying this kind of heavy smoking has some kind of association – and it looks like a fairly strong association – with the development of the disease," he said.

One limitation of the study is that researchers collected data only about smoking habits among middle-aged people; it did not look at what happened among those who had quit after the initial survey, Whitmer said.

The research speaks to what the Alzheimer's Association Maintain Your Brain campaign is promoting: that brain health has a lot to do with overall health, Hepburn said.

"The brain is part of the body, it’s part of the whole and if you assault parts, it’s going to have an impact on the whole," he said.

soundoff (2,459 Responses)
  1. 007카지노

    This page certainly has all of the information I needed about this subject and didnít know who to ask.


    February 27, 2021 at 09:01 | Report abuse | Reply
  2. 더킹카지노


    February 27, 2021 at 18:14 | Report abuse | Reply
  3. 더킹카지노주소

    Great post. I am going through some of these issues as well..


    February 27, 2021 at 21:08 | Report abuse | Reply
  4. 더킹카지노주소

    I love it when individuals come together and share views. Great site, stick with it!


    February 27, 2021 at 22:12 | Report abuse | Reply
  5. https://www.sfweekly.com/uncategorized/best-cbd-oil-for-dogs-in-2019-cbd-oil-for-pets-reviews/

    Precisely the type of web content that enriches the internet. Thanks!


    February 27, 2021 at 22:21 | Report abuse | Reply
  6. https://www.sfweekly.com/uncategorized/best-cbd-oil-for-dogs-in-2019-cbd-oil-for-pets-reviews/

    Love the manner you cover this subject.


    February 27, 2021 at 23:14 | Report abuse | Reply
  7. 더킹카지노


    February 28, 2021 at 05:06 | Report abuse | Reply
  8. 더킹카지노


    February 28, 2021 at 08:36 | Report abuse | Reply
  9. 더킹카지노

    Excellent post. I am dealing with many of these issues as well..


    February 28, 2021 at 10:13 | Report abuse | Reply
  10. ClarkTauts

    ew1cj nliq2 0t2f

    February 28, 2021 at 11:04 | Report abuse | Reply
  11. www.theintouchnews.com business

    You can certainly see your expertise in the work you write. The world hopes for even more passionate writers like you who are not afraid to say how they believe. Always follow your heart.


    February 28, 2021 at 14:35 | Report abuse | Reply
  12. www.theintouchnews.com technology

    Whoa! This blog looks just like my old one! It's on a entirely different subject but it has pretty much the same page layout and design. Wonderful choice of colors!


    February 28, 2021 at 17:24 | Report abuse | Reply
  13. theintouchnews.com business

    Heya im for the first time here. I found this board and I find It truly useful & it helped me out a lot. I hope to give something back and help others like you helped me.


    February 28, 2021 at 18:21 | Report abuse | Reply
  14. www.theintouchnews.com politics

    Nice post. I be taught something more difficult on different blogs everyday. It's going to at all times be stimulating to learn content material from different writers and apply a bit of something from their store. Id desire to make use of some with the content material on my weblog whether you dont mind. Natually Ill offer you a link in your web blog. Thanks for sharing.


    February 28, 2021 at 19:55 | Report abuse | Reply
  15. ClarkTauts

    3nnb8 m2oqo c1lu

    March 1, 2021 at 11:31 | Report abuse | Reply
  16. www.theondecknews.com home

    Hey there just wanted to give you a quick heads up. The words in your post seem to be running off the screen in Opera. I'm not sure if this is a format issue or something to do with internet browser compatibility but I thought I'd post to let you know. The design and style look great though! Hope you get the problem fixed soon. Thanks


    March 1, 2021 at 11:32 | Report abuse | Reply
  17. Health Insurance Leads

    I was suggested this website by my cousin. I'm not sure whether this post is written by him as no one else know such detailed about my trouble. You're wonderful! Thanks!


    March 2, 2021 at 04:50 | Report abuse | Reply
  18. Auto Insurance Leads

    Keep functioning ,impressive job!


    March 2, 2021 at 05:15 | Report abuse | Reply
  19. Carbon steel pipe supplier

    Great looking web site. Presume you did a bunch of your very own html coding.


    March 2, 2021 at 08:06 | Report abuse | Reply
  20. boiler grade steel pipe size

    Truly, such a advantageous online site.


    March 2, 2021 at 10:49 | Report abuse | Reply
  21. Mutual Fund

    I was suggested this website by my cousin. I am not sure whether this post is written by him as no one else know such detailed about my problem. You are wonderful! Thanks!


    March 2, 2021 at 13:50 | Report abuse | Reply
  22. Top Mutual Funds

    Oh my goodness! an incredible article dude. Thanks However I am experiencing issue with ur rss . Don’t know why Unable to subscribe to it. Is there anyone getting similar rss problem? Anyone who knows kindly respond. Thnkx


    March 2, 2021 at 14:35 | Report abuse | Reply
  23. Best Mutual Funds

    I absolutely love your blog and find a lot of your post's to be just what I'm looking for. Does one offer guest writers to write content available for you? I wouldn't mind writing a post or elaborating on a number of the subjects you write about here. Again, awesome weblog!


    March 2, 2021 at 16:59 | Report abuse | Reply
  24. www.thetuckernews.com fitness

    Very nice post. I just stumbled upon your weblog and wished to say that I have truly enjoyed browsing your blog posts. After all Ill be subscribing to your rss feed and I hope you write again very soon!


    March 2, 2021 at 17:33 | Report abuse | Reply
  25. www.thetuckernews.com lifestyle

    Wow that was unusual. I just wrote an incredibly long comment but after I clicked submit my comment didn't show up. Grrrr... well I'm not writing all that over again. Anyhow, just wanted to say wonderful blog!


    March 2, 2021 at 22:59 | Report abuse | Reply
  26. best panerai replica fake ladies rolex watches uk

    Extremely individual pleasant site. Astounding information offered on couple of clicks on.


    March 2, 2021 at 23:07 | Report abuse | Reply
  27. Keenan Kortum

    I’m not that much of a online reader to be honest but your blogs really nice, keep it up! I'll go ahead and bookmark your website to come back later. All the best


    March 3, 2021 at 00:23 | Report abuse | Reply
  28. wearethenationnews.com style

    of course like your web-site but you need to check the spelling on several of your posts. Several of them are rife with spelling issues and I find it very bothersome to tell the truth nevertheless I will certainly come back again.


    March 3, 2021 at 06:52 | Report abuse | Reply
  29. www.wearethenationnews.com entertainment

    I think this is one of the most important info for me. And i am glad reading your article. But want to remark on some general things, The site style is ideal, the articles is really great : D. Good job, cheers


    March 3, 2021 at 08:35 | Report abuse | Reply
  30. Political News

    I'm not sure exactly why but this weblog is loading extremely slow for me. Is anyone else having this issue or is it a problem on my end? I'll check back later on and see if the problem still exists.


    March 3, 2021 at 09:16 | Report abuse | Reply
  31. TechNews

    Thanks for the marvelous posting! I really enjoyed reading it, you're a great author.I will remember to bookmark your blog and will often come back from now on. I want to encourage you to continue your great job, have a nice evening!


    March 3, 2021 at 11:19 | Report abuse | Reply
  32. Political News

    Thanks , I have just been searching for info about this subject for ages and yours is the greatest I have discovered so far. But, what about the bottom line? Are you sure about the source?


    March 3, 2021 at 12:49 | Report abuse | Reply
  33. 우리카지노


    March 3, 2021 at 16:15 | Report abuse | Reply
  34. www.wearethenationnews.com money

    Wow! Thank you! I constantly needed to write on my site something like that. Can I implement a part of your post to my site?


    March 3, 2021 at 17:21 | Report abuse | Reply
  35. www.wearethenationnews.com entertainment

    Whats up! I just would like to give a huge thumbs up for the great data you've got here on this post. I can be coming again to your blog for extra soon.


    March 3, 2021 at 21:00 | Report abuse | Reply
  36. 바카라사이트주소


    March 3, 2021 at 21:52 | Report abuse | Reply
  37. wearethenationnews

    Hello There. I found your blog using msn. This is a very well written article. I will be sure to bookmark it and return to read more of your useful info. Thanks for the post. I will certainly comeback.


    March 3, 2021 at 22:31 | Report abuse | Reply
  38. Cameron Klingenberg

    Encontre as Melhores Ofertas e Cupons no Os10Melhor. Reunimos promoções de Smartphones, TVs, Moda e muito mais. O menor preço nas melhores lojas.


    March 3, 2021 at 23:57 | Report abuse | Reply
  39. 우리카지노

    Nice post. I learn something new and challenging on sites I stumbleupon everyday. It will always be exciting to read through content from other writers and use something from other websites.


    March 4, 2021 at 00:01 | Report abuse | Reply
  40. 출장


    March 4, 2021 at 03:16 | Report abuse | Reply
  41. 우리카지노

    I was able to find good information from your articles.


    March 4, 2021 at 07:26 | Report abuse | Reply
  42. Leonora Schlissel

    Encontre as Melhores Ofertas e Cupons no Os10Melhores. Reunimos promoções de Smartphones, TVs, Moda e muito mais. O menor preço nas melhores lojas.


    March 4, 2021 at 07:52 | Report abuse | Reply
  43. 바카라사이트


    March 4, 2021 at 08:28 | Report abuse | Reply
  44. 출장안마


    March 4, 2021 at 08:49 | Report abuse | Reply
  45. Clelia Frederique

    Hmm it seemsappearslooks like your sitewebsiteblog ate my first comment (it was extremelysuper long) so I guess I'll just sum it up what I submittedhad writtenwrote and say, I'm thoroughly enjoying your blog. I as welltoo am an aspiring blog bloggerwriter but I'm still new to the whole thingeverything. Do you have any helpful hintsrecommendationstips and hintspointssuggestionstips for inexperiencedfirst-timerookienovicebeginnernewbie blog writers? I'd certainlydefinitelygenuinelyreally appreciate it.


    March 4, 2021 at 10:30 | Report abuse | Reply
  46. http://thetrailblazingnews.com/

    Well I truly enjoyed reading it. This tip offered by you is very practical for good planning.


    March 4, 2021 at 10:57 | Report abuse | Reply
  47. www.thetrailblazingnews.com home

    I used to be very happy to search out this net-site.I wanted to thanks for your time for this wonderful learn!! I definitely enjoying every little bit of it and I have you bookmarked to check out new stuff you weblog post.


    March 4, 2021 at 13:49 | Report abuse | Reply
  48. travelers notebook

    Hey! I really could have sworn I've gone to this blog before but after browsing through several of
    the post I realized it's a novice to me. Nonetheless, I'm definitely
    delighted I discovered it and I'll be bookmarking and checking back frequently!

    my site travelers notebook

    March 4, 2021 at 15:16 | Report abuse | Reply
  49. thetrailblazingnews.com

    What i do not realize is actually how you're not really much more well-liked than you may be right now. You're so intelligent. You realize thus considerably relating to this subject, produced me personally consider it from numerous varied angles. Its like men and women aren't fascinated unless it is one thing to accomplish with Lady gaga! Your own stuffs excellent. Always maintain it up!


    March 4, 2021 at 16:26 | Report abuse | Reply
  50. 우리카지노쿠폰

    You need to be a part of a contest for one of the best websites on the net. I will highly recommend this site!


    March 4, 2021 at 16:31 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49

Leave a Reply to Best Mutual Funds


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.