Smoking boosts risk for Alzheimer's
October 25th, 2010
04:52 PM ET

Smoking boosts risk for Alzheimer's

Here's yet another reason to stop smoking: It elevates the risk of Alzheimer's disease and vascular dementia, according to a new study.

An analysis of more than 20,000 men and women found a 157 percent heightened risk of Alzheimer's disease in people who had smoked more than two packs of cigarettes a day. For vascular dementia, the second most common form of dementia, these smokers had a 172 percent increased risk.

"Dementia is a disease that crops up in late life, and that becomes clinically apparent, but I think people really need to think about risk factors for it over the life course," said Rachel Whitmer, study co-author and research scientist with Kaiser Permanente Division of Research in Oakland, California.

The study, sponsored by Kaiser Permanente, is published in the Archives of Internal Medicine.

Researchers say the association between smoking and various forms of dementia is strong, but they do not know exactly why. It has been shown before that people who smoke are more likely to have hypertension and cerebral vascular disease, as well as inflammation, Whitmer said. Smoking may contribute to the damage of brain blood vessels in addition to brain cells, she said.

The data came from Kaiser Permanente Northern California members surveyed between 1978 and 1985. At that time, they were between ages 50 and 60. Diagnoses of various forms of dementia among these people were made from 1994 to 2008, and researchers took that information from electronic health records. The participants in this study were all alive and still members of the health plan in 1994.

Researchers found that associations with the development of the disease are more modest among smokers who use up fewer than two packs a day, but still significant. Those who smoked a half-pack to one pack a day had an overall 37 percent elevated risk of dementia, and those who smoked between one and two packs had a 44 percent heightened risk, compared to non-smokers.

But this could be an underestimation, because some smokers who would have developed dementia died before diagnosis, said Kenneth Hepburn, associate dean for research at the Emory University School of Nursing, who was not involved in the study.

The reported risk of dementia among heavy smokers is also likely an underestimation because many of those people will die before they're old enough to develop dementia, he said.

While the elevated risk for various forms of dementia was shown for those smoking two packs a day in midlife, smoking less than half a pack of cigarettes a day, or having smoked in the past, did not appear to raise the risk compared with nonsmokers.

Hepburn found the study compelling, and noted that it incorporated an ethnically diverse population of both men and women.

"This gives great confidence in saying this kind of heavy smoking has some kind of association – and it looks like a fairly strong association – with the development of the disease," he said.

One limitation of the study is that researchers collected data only about smoking habits among middle-aged people; it did not look at what happened among those who had quit after the initial survey, Whitmer said.

The research speaks to what the Alzheimer's Association Maintain Your Brain campaign is promoting: that brain health has a lot to do with overall health, Hepburn said.

"The brain is part of the body, it’s part of the whole and if you assault parts, it’s going to have an impact on the whole," he said.

soundoff (2,459 Responses)
  1. http://thetrailblazingnews.com/

    Hello! Do you know if they make any plugins to help with Search Engine Optimization? I'm trying to get my blog to rank for some targeted keywords but I'm not seeing very good gains. If you know of any please share. Kudos!


    February 21, 2021 at 05:04 | Report abuse | Reply
  2. Clair Corcino

    Everything is very open with a very clearclearprecisereally clear explanationdescriptionclarification of the issueschallenges. It was trulyreallydefinitely informative. Your website isYour site is very usefulvery helpfulextremely helpfuluseful. Thanks forThank you forMany thanks for sharing!


    February 21, 2021 at 07:12 | Report abuse | Reply
  3. 샌즈카지노쿠폰

    This website certainly has all the info I wanted concerning this subject and didnít know who to ask.


    February 21, 2021 at 10:32 | Report abuse | Reply
  4. 샌즈카지노


    February 21, 2021 at 11:42 | Report abuse | Reply
  5. 샌즈카지노주소


    February 21, 2021 at 16:20 | Report abuse | Reply
  6. 샌즈카지노


    February 21, 2021 at 17:34 | Report abuse | Reply
  7. 샌즈카지노쿠폰


    February 22, 2021 at 01:04 | Report abuse | Reply
  8. click here

    Howdy I am so thrilled I found your blog page, I really found you by accident, while I was researching on Digg for something else, Nonetheless I am here now and would just like to say many thanks for a incredible post and a all round thrilling blog (I also love the theme/design), I dont have time to browse it all at the minute but I have saved it and also included your RSS feeds, so when I have time I will be back to read a lot more, Please do keep up the excellent job.

    February 22, 2021 at 04:58 | Report abuse | Reply
  9. 울산출장

    Aw, this was an extremely good post. Taking the time and actual effort to make a good article횜 but what can I say횜 I hesitate a lot and never seem to get nearly anything done.


    February 22, 2021 at 11:19 | Report abuse | Reply
  10. 샌즈카지노쿠폰


    February 22, 2021 at 12:36 | Report abuse | Reply
  11. www.twitter.com/clipsitnet

    Ill right away grab your rss as I can not find your e-mail subscription link or newsletter service. Do you have any? Kindly let me know in order that I could subscribe. Thanks.

    February 22, 2021 at 13:10 | Report abuse | Reply
  12. 메리트카지노


    February 22, 2021 at 15:31 | Report abuse | Reply
  13. 메리트카지노쿠폰


    February 23, 2021 at 00:37 | Report abuse | Reply
  14. Harold Eigner

    I am really impressed with your writing skills as well as with the layout on your weblog. Is this a paid theme or did you modify it yourself? Anyway keep up the nice quality writing, it’s rare to see a great blog like this one today..


    February 23, 2021 at 02:46 | Report abuse | Reply
  15. 메리트카지노

    This website was... how do you say it? Relevant!! Finally I have found something that helped me. Thanks a lot!


    February 23, 2021 at 05:10 | Report abuse | Reply
  16. https://www.facebook.com/clipsitnet

    Valuable information. Lucky me I found your web site by accident, and I'm shocked why this accident didn't happened earlier! I bookmarked it.


    February 23, 2021 at 08:17 | Report abuse | Reply
  17. facebook com clipsitnet

    Great site. A lot of useful info here. I am sending it to some friends ans also sharing in delicious. And of course, thanks for your effort!

    February 23, 2021 at 08:42 | Report abuse | Reply
  18. 메리트카지노쿠폰

    Greetings! Very useful advice in this particular article! It is the little changes that produce the biggest changes. Many thanks for sharing!


    February 23, 2021 at 09:12 | Report abuse | Reply
  19. https://www.sfweekly.com/uncategorized/best-cbd-oil-near-me-buy-cbd-oil-online/

    Specifically the type of material that enhances the internet. Thanks!


    February 23, 2021 at 11:23 | Report abuse | Reply
  20. 메리트카지노


    February 23, 2021 at 12:23 | Report abuse | Reply
  21. buy semenax amazon

    I’ve learn several excellent stuff here. Certainly worth bookmarking for revisiting. I surprise how so much effort you place to create the sort of magnificent informative web site.


    February 23, 2021 at 14:00 | Report abuse | Reply
  22. clipsitnet

    Hello, i think that i saw you visited my weblog thus i came to return the favor.I'm trying to find things to enhance my site!I suppose its ok to use a few of your ideas!!

    February 23, 2021 at 14:01 | Report abuse | Reply
  23. 메리트카지노주소

    I love reading through an article that can make men and women think. Also, thank you for allowing me to comment!


    February 23, 2021 at 14:57 | Report abuse | Reply
  24. click here facebook clipsitnet

    Thank you for the good writeup. It in fact was a amusement account it. Look advanced to far added agreeable from you! However, how could we communicate?

    February 23, 2021 at 15:30 | Report abuse | Reply
  25. semenax commercial music

    Hello, i read your blog from time to time and i own a similar one and i was just curious if you get a lot of spam feedback? If so how do you reduce it, any plugin or anything you can suggest? I get so much lately it's driving me mad so any help is very much appreciated.


    February 23, 2021 at 20:49 | Report abuse | Reply
  26. 메리트카지노주소


    February 24, 2021 at 02:54 | Report abuse | Reply
  27. sfweekly.com

    I love the manner you have actually concluded this post ...


    February 24, 2021 at 05:47 | Report abuse | Reply
  28. diigo.com

    Hi my friend! I wish to say that this article is awesome, nice written and include approximately all important infos. Id like to see more posts like this.


    February 24, 2021 at 08:41 | Report abuse | Reply
  29. read this

    Its arduous to find educated folks on this subject, however you sound like you already know what youre speaking about! Thanks


    February 24, 2021 at 10:09 | Report abuse | Reply
  30. 메리트카지노쿠폰


    February 24, 2021 at 16:18 | Report abuse | Reply
  31. boiler grade steel pipe Distributors

    Love the site– very individual friendly and lots to see!


    February 25, 2021 at 05:19 | Report abuse | Reply
  32. water freedom system 900

    A person necessarily help to make critically articles I would state. That is the first time I frequented your website page and so far? I surprised with the analysis you made to create this particular publish extraordinary. Wonderful task!


    February 25, 2021 at 07:00 | Report abuse | Reply
  33. 메리트카지노

    Nice post. I learn something totally new and challenging on sites I stumbleupon everyday. It's always helpful to read articles from other writers and use a little something from their web sites.


    February 25, 2021 at 07:33 | Report abuse | Reply
  34. click here

    I've been browsing online more than 3 hours today, yet I never found any interesting article like yours. Its pretty worth enough for me. In my view, if all web owners and bloggers made good content as you did, the internet will be much more useful than ever before.


    February 25, 2021 at 08:19 | Report abuse | Reply
  35. diigo.com

    This really answered my downside, thanks!


    February 25, 2021 at 22:31 | Report abuse | Reply
  36. steel line pipe supplier

    Your data is amazingly exciting.


    February 26, 2021 at 00:34 | Report abuse | Reply
  37. Pay and Shop

    You really make it seem so easy with your presentation but I find this matter to be really something that I think I would never understand. It seems too complicated and very broad for me. I am looking forward for your next post, I will try to get the hang of it!


    February 26, 2021 at 04:17 | Report abuse | Reply
  38. Know More

    This web page can be a walk-by for all of the data you wished about this and didn’t know who to ask. Glimpse here, and you’ll definitely uncover it.


    February 26, 2021 at 06:15 | Report abuse | Reply
  39. Link

    Great paintings! This is the type of info that should be shared around the web. Shame on Google for now not positioning this publish upper! Come on over and discuss with my web site . Thank you =)


    February 26, 2021 at 06:25 | Report abuse | Reply
  40. Paz Kalbach



    February 26, 2021 at 09:08 | Report abuse | Reply
  41. vreyro linomit

    I think you have observed some very interesting points, appreciate it for the post.


    February 26, 2021 at 11:28 | Report abuse | Reply
  42. 007카지노

    An intriguing discussion is worth comment. I believe that you need to write more on this subject matter, it may not be a taboo matter but typically people do not discuss these topics. To the next! Kind regards!!


    February 26, 2021 at 15:36 | Report abuse | Reply
  43. Urls

    Of course, what a splendid website and enlightening posts, I will bookmark your site.Have an awsome day!


    February 26, 2021 at 17:54 | Report abuse | Reply
  44. 007카지노주소


    February 26, 2021 at 18:52 | Report abuse | Reply
  45. 007카지노

    You should take part in a contest for one of the finest websites on the web. I will highly recommend this site!


    February 26, 2021 at 19:44 | Report abuse | Reply
  46. Urls

    Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You clearly know what youre talking about, why waste your intelligence on just posting videos to your site when you could be giving us something enlightening to read?


    February 26, 2021 at 20:25 | Report abuse | Reply
  47. 007카지노

    Itís hard to find well-informed people in this particular topic, however, you sound like you know what youíre talking about! Thanks


    February 26, 2021 at 21:38 | Report abuse | Reply
  48. Urls

    I was more than happy to find this web-site.I needed to thanks in your time for this wonderful read!! I undoubtedly having fun with every little bit of it and I've you bookmarked to check out new stuff you weblog post.


    February 26, 2021 at 23:41 | Report abuse | Reply
  49. 007카지노쿠폰


    February 27, 2021 at 01:36 | Report abuse | Reply
  50. CBD For Dogs

    Precisely the kind of web content that improves the web. Many thanks!


    February 27, 2021 at 02:25 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49

Leave a Reply to windows microsoft office home and business 2019


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.