October 25th, 2010
04:27 PM ET

How you react to lost sleep may be in your genes

Genetics may affect an individual's response to sleep deprivation, according to a study published in the journal Neurology.

Researchers at the University of Pennsylvania School of Medicine studied 92 people who did not carry the gene DQB1*0602 and 37 people who were carriers of the gene, whom they considered to be healthy sleepers. The gene is closely associated with narcolepsy, a disorder characterized by excessive daytime sleepiness and caused by the brain's inability to normally regulate sleep-wake cycles. Not everyone who has the gene variant has narcolepsy.

In the study, subjects spent 10 hours in bed during the first two baseline nights. On the following five nights, they were given only four hours to spend in bed, and the rest of the night was spent awake reading, playing games, watching movies or talking with staff, to replicate partial sleep deprivation.

The researchers found the test subjects with people the gene variant rated themselves as being more sleepy while fully rested and sleep deprived.

"When we looked at their physiological sleep, we looked at the drive to sleep, we found that they had lower levels than the negative people," said study author Dr. Namni Goel.

Researchers also found individuals who carry the gene have more fragmented sleep, which translates into less deeper, more restorative sleep typically found in Stage 3 sleep; instead, more time was spent in stage 2 sleep. The presence of the gene did not impact memory and cognitive performance; both groups showed a slowdown, according to the researchers.

Goel noted that the study participants were all between 22 and 45 years of age. "You can't generalize our findings. It really is restricted to that population," she said.

"Different genes are probably regulating different aspects-whether it's how you rate yourself or how you perform, or this inherent sleep drive," Goel added. "This is one gene and we're continuing to look for others. The data should be replicated, but it gives us a hint of why some people respond better than others to sleep loss."

« Previous entry
soundoff (145 Responses)
  1. 파워볼 전용사이트

    After looking over a number of the blog posts on your web site, I honestly appreciate your technique of blogging. I book-marked it to my bookmark site list and will be checking back soon. Please check out my website too and tell me your opinion.


    June 7, 2021 at 06:10 | Report abuse | Reply
  2. Zetta Kofoid

    My developer is trying to persuade me to move to .net from PHP. I have always disliked the idea because of the costs. But he's tryiong none the less. I've been using WordPress on several websites for about a year and am nervous about switching to another platform. I have heard fantastic things about blogengine.net. Is there a way I can import all my wordpress content into it? Any kind of help would be really appreciated!


    June 7, 2021 at 07:57 | Report abuse | Reply
  3. Eugene Conces

    I savour, cause I found just what I used to be taking a look for. You've ended my 4 day long hunt! God Bless you man. Have a great day. Bye


    June 7, 2021 at 08:53 | Report abuse | Reply
  4. 먹튀검증업체

    Good post. I learn something totally new and challenging on websites I stumbleupon on a daily basis. It will always be interesting to read through content from other writers and use something from their web sites.


    June 7, 2021 at 11:57 | Report abuse | Reply
  5. 먹튀커뮤니티

    I need to to thank you for this fantastic read!! I absolutely enjoyed every little bit of it. I have got you bookmarked to look at new stuff you postÖ


    June 7, 2021 at 17:54 | Report abuse | Reply
  6. 부산출장마사지

    You've made some good points there. I checked on the internet for more information about the issue and found most individuals will go along with your views on this web site.


    June 8, 2021 at 00:32 | Report abuse | Reply
  7. 청주출장안마후불

    Your style is so unique in comparison to other folks I have read stuff from. Thank you for posting when you've got the opportunity, Guess I will just bookmark this site.


    June 8, 2021 at 01:06 | Report abuse | Reply
  8. wandavision final costume

    WandaVision's period finale provided us the initial proper take a look at Wanda's superhero attire.


    June 8, 2021 at 11:23 | Report abuse | Reply
  9. Palmer Fragassi

    very nice submit, i certainly love this website, carry on it


    June 8, 2021 at 14:46 | Report abuse | Reply
  10. 청주출장마사지후불

    Pretty! This was an extremely wonderful post. Thank you for supplying this information.


    June 8, 2021 at 23:09 | Report abuse | Reply
  11. 부산출장

    There's certainly a great deal to learn about this issue. I love all the points you made.


    June 9, 2021 at 00:14 | Report abuse | Reply
  12. Albina Mccrae

    Heya i’m for the first time here. I came across this board and I find It truly useful & it helped me out a lot. I hope to give something back and aid others like you helped me.


    June 9, 2021 at 00:16 | Report abuse | Reply
  13. Harley Egnew

    Simply want to say your article is as astounding. The clarity in your publish is just spectacular and that i could think you are a professional on this subject. Well together with your permission let me to clutch your feed to stay updated with approaching post. Thank you a million and please continue the gratifying work.


    June 9, 2021 at 03:46 | Report abuse | Reply
  14. Rudolf Marinese

    I found your blog web site on google and test a number of of your early posts. Proceed to keep up the excellent operate. I simply extra up your RSS feed to my MSN News Reader. Searching for ahead to studying extra from you later on!…


    June 9, 2021 at 11:52 | Report abuse | Reply
  15. Sharan Cottrill

    Hey very nice web site!! Man .. Excellent .. Amazing .. I will bookmark your site and take the feeds also…I am happy to find numerous useful information here in the post, we need develop more techniques in this regard, thanks for sharing. . . . . .


    June 9, 2021 at 23:05 | Report abuse | Reply
  16. Julio Sadat

    I’ll immediately grab your rss feed as I can't find your e-mail subscription link or newsletter service. Do you have any? Please let me know in order that I could subscribe. Thanks.


    June 10, 2021 at 02:26 | Report abuse | Reply
  17. Regina Lagatella

    Today, I went to the beach front with my children. I found a sea shell and gave it to my 4 year old daughter and said "You can hear the ocean if you put this to your ear." She placed the shell to her ear and screamed. There was a hermit crab inside and it pinched her ear. She never wants to go back! LoL I know this is entirely off topic but I had to tell someone!


    June 10, 2021 at 05:06 | Report abuse | Reply
  18. 울산출장

    I was able to find good info from your blog posts.


    June 10, 2021 at 07:41 | Report abuse | Reply
  19. Jacquelyn Lavanway

    Thanks for some other informative web site. The place else could I get that kind of info written in such an ideal manner? I've a undertaking that I am just now working on, and I've been at the look out for such information.


    June 10, 2021 at 07:46 | Report abuse | Reply
  20. Leo Hafer

    I love your blog.. very nice colors & theme. Did you make this website yourself or did you hire someone to do it for you? Plz respond as I'm looking to create my own blog and would like to find out where u got this from. thanks a lot


    June 10, 2021 at 15:32 | Report abuse | Reply
  21. 울산출장안마

    Itís nearly impossible to find experienced people in this particular subject, but you seem like you know what youíre talking about! Thanks


    June 10, 2021 at 19:03 | Report abuse | Reply
  22. Stasia Wyman

    Hi there! Someone in my Facebook group shared this website with us so I came to give it a look. I'm definitely enjoying the information. I'm book-marking and will be tweeting this to my followers! Exceptional blog and wonderful design and style.


    June 11, 2021 at 00:22 | Report abuse | Reply
  23. Hal Omelia

    I am really loving the theme/design of your web site. Do you ever run into any web browser compatibility issues? A handful of my blog visitors have complained about my site not working correctly in Explorer but looks great in Opera. Do you have any suggestions to help fix this issue?


    June 11, 2021 at 04:55 | Report abuse | Reply
  24. 울산출장안마

    Great blog you have here.. Itís difficult to find high-quality writing like yours these days. I honestly appreciate individuals like you! Take care!!


    June 11, 2021 at 05:09 | Report abuse | Reply
  25. Mac Sheikh

    Wow! This blog looks just like my old one! It's on a totally different topic but it has pretty much the same page layout and design. Great choice of colors!


    June 11, 2021 at 08:46 | Report abuse | Reply
  26. 먹튀검증

    Iím impressed, I must say. Rarely do I come across a blog thatís equally educative and amusing, and without a doubt, you have hit the nail on the head. The problem is something which not enough folks are speaking intelligently about. I am very happy I stumbled across this in my search for something concerning this.


    June 12, 2021 at 03:16 | Report abuse | Reply
  27. 먹튀 검증

    It's a jealous article. It's very remarkable and innovative. Who can be you to write this specific special article?


    June 12, 2021 at 06:19 | Report abuse | Reply
  28. Hertha Cohenour

    I’ve been exploring for a little bit for any high quality articles or blog posts in this kind of space . Exploring in Yahoo I eventually stumbled upon this web site. Studying this info So i am glad to show that I have a very just right uncanny feeling I found out just what I needed. I such a lot definitely will make certain to don’t put out of your mind this website and give it a look on a continuing basis.


    June 12, 2021 at 10:08 | Report abuse | Reply
  29. Jerrold Votolato

    I am very happy to read this. This is the kind of manual that needs to be given and not the accidental misinformation that’s at the other blogs. Appreciate your sharing this greatest doc.


    June 12, 2021 at 10:30 | Report abuse | Reply
  30. 인천출장안마

    The very next time I read a blog, Hopefully it won't disappoint me as much as this one. I mean, Yes, it was my choice to read through, but I actually believed you would have something helpful to talk about. All I hear is a bunch of moaning about something you can fix if you were not too busy looking for attention.


    June 12, 2021 at 18:18 | Report abuse | Reply
  31. 인천 출장안마

    Howdy! This blog post couldnít be written much better! Reading through this post reminds me of my previous roommate! He constantly kept talking about this. I am going to forward this post to him. Fairly certain he's going to have a good read. Thanks for sharing!


    June 13, 2021 at 00:45 | Report abuse | Reply
  32. Dede Bethany

    Definitely believe that which you said. Your favorite reason appeared to be on the internet the easiest thing to be aware of. I say to you, I certainly get annoyed while people consider worries that they plainly do not know about. You managed to hit the nail upon the top as well as defined out the whole thing without having side-effects , people can take a signal. Will likely be back to get more. Thanks


    June 13, 2021 at 01:55 | Report abuse | Reply
  33. Millicent Hulsman

    I would like to convey my love for your generosity giving support to those who must have assistance with in this topic. Your very own commitment to passing the solution around turned out to be surprisingly helpful and have in every case helped professionals much like me to arrive at their ambitions. Your entire informative facts entails this much a person like me and far more to my office colleagues. Many thanks; from everyone of us.


    June 13, 2021 at 22:52 | Report abuse | Reply
  34. Frankie Bausman

    This site is really a stroll-by means of for all of the information you needed about this and didn’t know who to ask. Glimpse right here, and also you’ll definitely uncover it.


    June 14, 2021 at 00:28 | Report abuse | Reply
  35. Leonel Holmgren

    It's a shame you don't have a donate button! I'd definitely donate to this excellent blog! I suppose for now i'll settle for bookmarking and adding your RSS feed to my Google account. I look forward to fresh updates and will share this site with my Facebook group. Talk soon!


    June 14, 2021 at 01:45 | Report abuse | Reply
  36. Marine Maxedon

    I simply couldn't go away your website prior to suggesting that I extremely loved the standard info a person supply on your visitors? Is going to be again incessantly to check out new posts


    June 14, 2021 at 05:23 | Report abuse | Reply
  37. Lashay Militello

    Hmm it looks like your website ate my first comment (it was super long) so I guess I'll just sum it up what I had written and say, I'm thoroughly enjoying your blog. I as well am an aspiring blog blogger but I'm still new to the whole thing. Do you have any tips and hints for beginner blog writers? I'd definitely appreciate it.


    June 14, 2021 at 07:32 | Report abuse | Reply
  38. Patsy Stehlik

    Pretty section of content. I just stumbled upon your web site and in accession capital to assert that I acquire in fact enjoyed account your blog posts. Any way I will be subscribing to your feeds and even I achievement you access consistently fast.


    June 14, 2021 at 16:00 | Report abuse | Reply
  39. Elise Yeaton

    I like what you guys are up also. Such intelligent work and reporting! Carry on the superb works guys I’ve incorporated you guys to my blogroll. I think it will improve the value of my site 🙂


    June 15, 2021 at 01:59 | Report abuse | Reply
  40. Kenda Homby

    I want to show my respect for your kind-heartedness giving support to people that absolutely need assistance with this one situation. Your special commitment to getting the message up and down was definitely interesting and has continuously empowered people like me to get to their ambitions. Your warm and helpful tips and hints implies a whole lot a person like me and even further to my peers. Thanks a lot; from everyone of us.


    June 15, 2021 at 17:42 | Report abuse | Reply
  41. Dorla Hazelgrove

    I have been reading out some of your stories and i can state pretty nice stuff. I will definitely bookmark your blog.


    June 16, 2021 at 07:03 | Report abuse | Reply
  42. Contessa Leaming

    Normally I do not read post on blogs, but I would like to say that this write-up very forced me to take a look at and do it! Your writing taste has been amazed me. Thank you, very great article.


    June 16, 2021 at 10:08 | Report abuse | Reply
  43. CBD Lube

    Way cool! Some very valid points! I appreciate you penning this post and also the rest of the website is very good.


    June 16, 2021 at 11:36 | Report abuse | Reply
  44. Roxy Vermette

    You made some first rate points there. I regarded on the web for the issue and located most people will associate with along with your website.


    June 17, 2021 at 00:03 | Report abuse | Reply
  45. Danika Hohm

    Hey there! Do you know if they make any plugins to safeguard against hackers? I'm kinda paranoid about losing everything I've worked hard on. Any suggestions?


    June 17, 2021 at 01:52 | Report abuse | Reply
  46. 파워볼 사이트

    I like reading an article that will make men and women think. Also, thank you for allowing for me to comment!


    June 17, 2021 at 04:02 | Report abuse | Reply
  47. Don Muellerleile

    Its like you read my thoughts! You seem to understand a lot approximately this, like you wrote the guide in it or something. I feel that you just could do with some p.c. to drive the message home a bit, but instead of that, this is fantastic blog. An excellent read. I will certainly be back.


    June 17, 2021 at 05:27 | Report abuse | Reply
  48. Jon Farman

    I do love the way you have framed this particular concern plus it does indeed offer me a lot of fodder for thought. However, from what precisely I have witnessed, I just simply trust when the feedback pile on that folks remain on issue and don't get started upon a tirade associated with some other news of the day. Yet, thank you for this exceptional point and while I can not necessarily go along with this in totality, I value the standpoint.


    June 17, 2021 at 21:12 | Report abuse | Reply
  49. Jaime Eggington

    There is perceptibly a bundle to identify about this. I consider you made various good points in features also.


    June 17, 2021 at 23:43 | Report abuse | Reply
  50. Lory Sieber

    I am really impressed with your writing skills and also with the layout on your weblog. Is this a paid theme or did you customize it yourself? Anyway keep up the excellent quality writing, it is rare to see a great blog like this one nowadays..


    June 18, 2021 at 01:36 | Report abuse | Reply
1 2 3

Post a comment


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

« Previous entry
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.