ADHD is a genetic condition, study says
September 29th, 2010
06:30 PM ET

ADHD is a genetic condition, study says

A new study in the Lancet provides the first direct evidence that genetic abnormalities are responsible for attention-deficit hyperactivity disorder, ADHD.

Although previous research had shown that ADHD can be inherited, no specific genes have been identified before that seem to underlie this condition. But that doesn't mean that someone with these particular genetic markers will have ADHD, experts say.

"This tells us that there is a biological marker that tells us that this person is susceptible to develop this disease," said Dr. Robert Marion, chief of genetics and developmental medicine at the Children’s Hospital at Montefiore and Albert Einstein College of Medicine, who was not involved in the study.

Researchers led by Dr. Nigel Williams at the Cardiff University School of Medicine in Wales fully analyzed data from 366 children with ADHD and 1,047 who did not have ADHD.

The Lancet study finds that children with ADHD have more large, rare copy-number variants than children without the condition. "Copy-number variants" are pieces of DNA that are either missing or extraneous in the chromosomes. Other studies have suggested that these variants may be associated with schizophrenia, autism, epilepsy, and other neurodevelopmental disorders.

Specifically, this study suggests a shared biological basis between ADHD and autism because of the shared genetic characteristics found in this study. Researchers also found genetic overlaps with schizophrenia.

""Eventually we’re going to be able to do testing that will identify susceptibility to ADHD or other conditions," Marion said.

But that test won't be available any time soon, especially because there appear to be a large number of variations in DNA that predispose a person to ADHD, Marion said.

The results suggest that ADHD is "not purely a social construct," the study authors wrote. "It’s a real hard and true disorder," Marion added.

On the other hand, this doesn't rule out environmental factors, Marion said. It may be that specific environments determine whether a person with these genetic variations goes on to develop ADHD, autism, schizophrenia, or nothing at all. However, scientists do not yet know precisely what those factors are.

In the future, as more becomes known about the genetics of ADHD, interventions may be tailored toward specific children before they begin to have serious problems in school, Marion said.

The study's "results are exciting, but how these findings will be clinically translated is still speculative," writes J. Peter Burbach, of the University Medical Center Utrecht in the Netherlands, in a Comment in the journal. More research should be done to further examine the associations between these genes and their outcomes.

ADHD has caused a great deal of controversy as parents struggle to appropriately treat their children.

Given that there may be nearly 1 million misdiagnoses of ADHD in the United States, a better grip on the biological basis of it may help mental health professionals distinguish ADHD from other problems.

soundoff (618 Responses)
  1. LbsoZisse

    cialis and paypal http://ucialisdas.com/ montreal drug cialis

    May 6, 2021 at 00:22 | Report abuse | Reply
  2. RebfZisse

    what works better cialis or viagra? http://rcialisgl.com/ cialis usa paypal

    May 6, 2021 at 22:50 | Report abuse | Reply
  3. LebnEncox

    compare prescription prices buying prescription drugs canada online pharmacy search

    May 7, 2021 at 01:58 | Report abuse | Reply
  4. LebnEncox

    pharma http://xlnpharmacy.com/ online canadian pharmacy

    May 7, 2021 at 02:45 | Report abuse | Reply
  5. JebgEncox

    mexican pharmacies shipping to usa drugs online online pharmacy no prescription needed

    May 7, 2021 at 06:50 | Report abuse | Reply
  6. GtnbCrulk

    viagra for sale ebay https://jokviagra.com/ mixing cialis and viagra

    May 7, 2021 at 07:13 | Report abuse | Reply
  7. AnooEncox

    what does viagra do to dogs https://llviagra.com/ can you use too much viagra

    May 7, 2021 at 07:52 | Report abuse | Reply
  8. clonidine hcl

    chloroquine side effects https://chloroquineorigin.com/ side effects of chloroquine

    May 7, 2021 at 14:53 | Report abuse | Reply
  9. LbsoZisse

    cialis for sale online http://ucialisdas.com/ cialis paypale

    May 7, 2021 at 20:50 | Report abuse | Reply
  10. JebgEncox

    mail order pharmacies http://pharmacylo.com/ canadian pharmacy reviews

    May 8, 2021 at 04:57 | Report abuse | Reply
  11. FmrfEncox

    cialis original https://cialisee.com/ price comparison viagra cialis levitra

    May 8, 2021 at 19:57 | Report abuse | Reply
  12. Etsuko Heckstall

    I really appreciate this post. I’ve been looking everywhere for this! Thank goodness I found it on Bing. You've made my day! Thanks again


    May 9, 2021 at 04:47 | Report abuse | Reply
  13. AnooEncox

    was ist besser viagra order kamagra http://llviagra.com/ viagra sans carte de credit

    May 9, 2021 at 05:03 | Report abuse | Reply
  14. BbshMile

    buy viagra online cheapest https://loxviagra.com/ – how much viagra should i take free viagra sample pack

    May 9, 2021 at 18:11 | Report abuse | Reply
  15. FmrfEncox

    cialis low prices http://cialisee.com/ – cialis generic viagra vs cialis

    May 11, 2021 at 04:01 | Report abuse | Reply
  16. BbshMile

    viagra uk https://loxviagra.com/ viagra canadian pharmacy

    May 12, 2021 at 01:44 | Report abuse | Reply
  17. GtnbCrulk

    buying viagra online reviews https://jokviagra.com/ viagra for sale

    May 12, 2021 at 05:31 | Report abuse | Reply
  18. RebfZisse

    where to get my prescription cialis filled https://rcialisgl.com/ cialis tadalafil online paypal

    May 12, 2021 at 11:51 | Report abuse | Reply
  19. stornobrzinol

    With havin so much content do you ever run into any problems of plagorism or copyright violation? My blog has a lot of unique content I've either authored myself or outsourced but it appears a lot of it is popping it up all over the internet without my permission. Do you know any ways to help protect against content from being stolen? I'd genuinely appreciate it.


    May 13, 2021 at 03:19 | Report abuse | Reply
  20. LbsoZisse

    generic cialis forums http://ucialisdas.com/ cialis canada online

    May 13, 2021 at 07:23 | Report abuse | Reply
  21. RebfZisse

    how much is a cialis http://rcialisgl.com/ – buy cialis online overnight delivery cialisfree pills

    May 14, 2021 at 04:16 | Report abuse | Reply
  22. AnooEncox

    news for viagra https://llviagra.com/ cialis sau viagra forum

    May 14, 2021 at 06:54 | Report abuse | Reply
  23. GtnbCrulk

    viagra coupon http://jokviagra.com/ buy viagra cheaper

    May 14, 2021 at 18:43 | Report abuse | Reply
  24. LbsoZisse

    cialis https://ucialisdas.com/ cialis 36 hour

    May 15, 2021 at 00:12 | Report abuse | Reply
  25. LebnEncox

    Atarax http://xlnpharmacy.com/ safe canadian pharmacies

    May 15, 2021 at 02:11 | Report abuse | Reply
  26. LebnEncox

    drug costs nearest drug store buy prescription drugs canada

    May 15, 2021 at 02:57 | Report abuse | Reply
  27. JebgEncox

    Florinef https://pharmacylo.com/ canadapharmacy24h

    May 15, 2021 at 06:58 | Report abuse | Reply
  28. FmrfEncox

    where to buy cialis in singapore https://cialisee.com/ cialis canada free trial

    May 15, 2021 at 13:32 | Report abuse | Reply
  29. AnooEncox

    es perjudicial el viagra https://llviagra.com/ what effect will viagra have on a woman

    May 15, 2021 at 21:16 | Report abuse | Reply
  30. JebgEncox

    safe canadian online pharmacies drug stores near me Tofranil

    May 16, 2021 at 01:22 | Report abuse | Reply
  31. BbshMile

    viagra samples walgreens http://loxviagra.com/ online generic viagra

    May 17, 2021 at 11:42 | Report abuse | Reply
  32. FmrfEncox

    cialis 20mg shopping http://cialisee.com/ cialis 20mg usa

    May 17, 2021 at 19:53 | Report abuse | Reply
  33. RebfZisse

    how to buy cialis from canada http://rcialisgl.com/ cipla cialis

    May 18, 2021 at 10:36 | Report abuse | Reply
  34. LbsoZisse

    cialis 40mg http://ucialisdas.com/ viagra and cialis discount

    May 19, 2021 at 18:18 | Report abuse | Reply
  35. LebnEncox

    canada meds best drugstore shampoo canada pharmacy 24h

    May 20, 2021 at 11:40 | Report abuse | Reply
  36. RebfZisse

    generica cialis http://rcialisgl.com/ best price cialis 20mg

    May 20, 2021 at 11:57 | Report abuse | Reply
  37. LebnEncox

    prescription drug http://xlnpharmacy.com/ Capoten

    May 20, 2021 at 12:15 | Report abuse | Reply
  38. JebgEncox

    online pharmacy without insurance https://pharmacylo.com/ Casodex

    May 20, 2021 at 15:34 | Report abuse | Reply
  39. BbshMile

    female viagra pill walmart http://loxviagra.com/ do you need a prescription for viagra

    May 20, 2021 at 19:03 | Report abuse | Reply
  40. GtnbCrulk

    how long does it take for viagra to work http://jokviagra.com/ viagra cost

    May 20, 2021 at 21:11 | Report abuse | Reply
  41. LbsoZisse

    pay cialis with paypal http://ucialisdas.com/ discount cialis 20mg

    May 21, 2021 at 03:27 | Report abuse | Reply
  42. JebgEncox

    rx pharmacy no prescription Estrace canada drugs

    May 21, 2021 at 12:03 | Report abuse | Reply
  43. FmrfEncox

    buy brand cialis overnight http://cialisee.com/ buy cialis cheap

    May 21, 2021 at 20:21 | Report abuse | Reply
  44. GtnbCrulk

    virectin vs viagra https://jokviagra.com/ – does viagra make your dick bigger cost of viagra at walmart

    May 23, 2021 at 13:20 | Report abuse | Reply
  45. AnooEncox

    kamagra viagra oral jelly http://llviagra.com/ viagra profits pfizer

    May 24, 2021 at 04:14 | Report abuse | Reply
  46. Tritreviewifind

    https://tadalafilww.com/ side effects of tadalafil cheap cialis pills for sale tadalafil brands side effects of tadalafil

    May 24, 2021 at 07:24 | Report abuse | Reply
  47. RebfZisse

    where to buy cialis http://rcialisgl.com/ cialis lion

    May 24, 2021 at 12:12 | Report abuse | Reply
  48. cyclosporine

    cyclosporine medication cyclosporine for humans

    May 24, 2021 at 17:25 | Report abuse | Reply
  49. LbsoZisse

    buy cialis no prescription australia https://ucialisdas.com/ cialis generic alternative

    May 25, 2021 at 00:16 | Report abuse | Reply
  50. Tritreviewifind

    best price usa tadalafil tadalafil dosage tadalafil cost in canada cost of cialis https://tadacipetadalafil.com/

    May 25, 2021 at 11:12 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10

Leave a Reply to Exposo


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.