ADHD is a genetic condition, study says
September 29th, 2010
06:30 PM ET

ADHD is a genetic condition, study says

A new study in the Lancet provides the first direct evidence that genetic abnormalities are responsible for attention-deficit hyperactivity disorder, ADHD.

Although previous research had shown that ADHD can be inherited, no specific genes have been identified before that seem to underlie this condition. But that doesn't mean that someone with these particular genetic markers will have ADHD, experts say.

"This tells us that there is a biological marker that tells us that this person is susceptible to develop this disease," said Dr. Robert Marion, chief of genetics and developmental medicine at the Children’s Hospital at Montefiore and Albert Einstein College of Medicine, who was not involved in the study.

Researchers led by Dr. Nigel Williams at the Cardiff University School of Medicine in Wales fully analyzed data from 366 children with ADHD and 1,047 who did not have ADHD.

The Lancet study finds that children with ADHD have more large, rare copy-number variants than children without the condition. "Copy-number variants" are pieces of DNA that are either missing or extraneous in the chromosomes. Other studies have suggested that these variants may be associated with schizophrenia, autism, epilepsy, and other neurodevelopmental disorders.

Specifically, this study suggests a shared biological basis between ADHD and autism because of the shared genetic characteristics found in this study. Researchers also found genetic overlaps with schizophrenia.

""Eventually we’re going to be able to do testing that will identify susceptibility to ADHD or other conditions," Marion said.

But that test won't be available any time soon, especially because there appear to be a large number of variations in DNA that predispose a person to ADHD, Marion said.

The results suggest that ADHD is "not purely a social construct," the study authors wrote. "It’s a real hard and true disorder," Marion added.

On the other hand, this doesn't rule out environmental factors, Marion said. It may be that specific environments determine whether a person with these genetic variations goes on to develop ADHD, autism, schizophrenia, or nothing at all. However, scientists do not yet know precisely what those factors are.

In the future, as more becomes known about the genetics of ADHD, interventions may be tailored toward specific children before they begin to have serious problems in school, Marion said.

The study's "results are exciting, but how these findings will be clinically translated is still speculative," writes J. Peter Burbach, of the University Medical Center Utrecht in the Netherlands, in a Comment in the journal. More research should be done to further examine the associations between these genes and their outcomes.

ADHD has caused a great deal of controversy as parents struggle to appropriately treat their children.

Given that there may be nearly 1 million misdiagnoses of ADHD in the United States, a better grip on the biological basis of it may help mental health professionals distinguish ADHD from other problems.

soundoff (618 Responses)
  1. LokuEncox

    impotence medicine for erectile canada pharmacy reviews

    January 12, 2021 at 07:14 | Report abuse | Reply
  2. NllpZisse

    the people's pharmacy family pharmacy 24 hr pharmacy near me

    January 12, 2021 at 19:15 | Report abuse | Reply
  3. JlloCrulk

    24 hours pharmacy erectile dysfunction treatment mail order pharmacy

    January 12, 2021 at 19:58 | Report abuse | Reply
  4. JtmfEncox

    rx pharmacy online pharmacies near me discount pharmacy card

    January 13, 2021 at 09:17 | Report abuse | Reply
  5. KlioMile

    discount generic viagra viagra store in las vegas viagra viagra online australia generis viagra buy viagra australia online no prescription viagra no prescription fast shipping viagra for sell brand viagra viagra price generic viagra sildenfil citrate australia best cheap website for viagra alternatives to viagra men buying viagra from sydney sample viagra package

    January 14, 2021 at 01:09 | Report abuse | Reply
  6. Verline Abbas

    I got what you mean , thankyou for posting .Woh I am lucky to find this website through google. "Don't be afraid of opposition. Remember, a kite rises against not with the wind." by Hamilton Mabie.


    January 15, 2021 at 23:40 | Report abuse | Reply
  7. FgnhZisse

    viagra samples free online pharmacy, mastercard, viagra viagra with dapoxetine 365 pills buy viagra online viagra buy paypal what does viagra cost at walmart generic viagra shoppers drug mart viagra generic viagra pill canadianlab viagra viagra heartburn viagra in korea viagra 100mg viagra online no prescription overnight delivery does liquid viagra

    January 16, 2021 at 05:13 | Report abuse | Reply
  8. JvcxCrulk

    best generic viagra viagra for women for sale viagra pills sale in greenville generic viagra orders accepted by mastercard walmart viagra price %viagra online viagra generic buy viagra from canada viagra online via paypal viagra 100mg viagra online generic buy pfizer viagra generic viagra 50mg buy viagra in sydney need to get samples of viagra without a perscription

    January 16, 2021 at 19:52 | Report abuse | Reply
  9. NlbxZisse

    viagra free trial offer free viagra pills viagra generica viagra price walmart liquid viagra shot shopping generic viagra viagra super active canada viagra users comments what does viagra cost in uk buy viagra online uk no prescription viagra cialis combo viagra canada pfizer viagra/cialis packs buy viagra toronto buy viagra from germany

    January 16, 2021 at 21:49 | Report abuse | Reply
  10. Aurea Vias


    January 17, 2021 at 23:02 | Report abuse | Reply
  11. KbctMile

    cialis with dapoxetine online cialis super active plus cialis online australia http://mycialedst.com/ – what color is cialis pill ’

    January 19, 2021 at 01:27 | Report abuse | Reply
  12. AqbvEncox

    viagra in hamburg viagra patent date viagra sales austra http://acialaarx.com/ – generic viagra without prescription ’

    January 20, 2021 at 15:31 | Report abuse | Reply
  13. Mertie Paulino


    January 21, 2021 at 04:37 | Report abuse | Reply
  14. FbdhZisse

    generic cialis professional 10mg cialis cialis online without a prescription http://21cialismen.com/ – can i buy cialis without prescription pay pal ’

    January 21, 2021 at 05:45 | Report abuse | Reply
  15. Viviana Ouellete


    January 21, 2021 at 11:36 | Report abuse | Reply
  16. JvcbxCrulk

    cialis prices walmart cialis super active experiences free cialis canada http://phrcialiled.com/ – viagra • cialis • ’

    January 21, 2021 at 17:34 | Report abuse | Reply
  17. NlbxZisse

    generic cialis buy cialis cheapest cialis doesn\'t work? http://cialijomen.com/ – cialis supplier uk ’

    January 21, 2021 at 22:22 | Report abuse | Reply
  18. LcxEncox

    viagra from canana without a prescription viagra professional super viagra 50 mg http://genqpviag.com/ – generic viagra from canada ’

    January 21, 2021 at 23:43 | Report abuse | Reply
  19. JbdcEncox

    buy cheap generic viagra best aftermarket viagra how to buy viagra melbourne http://llviabest.com/ – viagra samples paypal ’

    January 23, 2021 at 00:42 | Report abuse | Reply
  20. KbbtMile

    buying cialis internet canada rx generic cialis paypal https://xz-pharmacyonline.com – canadian pharmacies online ’

    January 23, 2021 at 18:22 | Report abuse | Reply
  21. AhmdEncox

    best price for cialis cheap cialis online order original cialis http://cialmenshoprx.com/ – generic cialis from india ’

    January 25, 2021 at 09:23 | Report abuse | Reply
  22. FbgZisse

    viagra alternatives over counter viagra online sales in australia generic viagra aus https://canadianpharmacy-usx.com/organic.htm – walmart viagra cost ’

    January 26, 2021 at 01:25 | Report abuse | Reply
  23. JnhCrulk

    cialis price cialis online doctor cialis edmonton http://loncialis.com/ – cialis lilly price ’

    January 26, 2021 at 01:34 | Report abuse | Reply
  24. NmilZisse

    canada viagra over 40 and viagra viagra replacements http://xz-pharmacyonline.com/en/career-opportunities.html – genaric viagra ’

    January 26, 2021 at 18:01 | Report abuse | Reply
  25. FmfvEncox

    generic cialis canada cialis 20 mg sell cialis generic no prescription http://sjcialis.com/ – cialis pills ’

    January 26, 2021 at 18:51 | Report abuse | Reply
  26. Jae Kusek

    I've been absent for a while, but now I remember why I used to love this site. Thanks, I'll try and check back more often. How frequently you update your site?


    January 28, 2021 at 22:10 | Report abuse | Reply
  27. KbbgMile

    buy viagra online canadian pharmaceuticals online safe 36 hour viagra http://erectilejyzd.com/ – Sporanox ’

    January 29, 2021 at 00:17 | Report abuse | Reply
  28. AhmdEncox

    cialis black brand Super ED Trial Pack cialis buy without https://impotencecdny.com/ – canadian pharmacy 365 ’

    January 30, 2021 at 16:33 | Report abuse | Reply
  29. FhnhZisse

    Speman buy drugs online pain relief https://canadianpharmacy-yy.com/ – Zyrtec ’

    January 31, 2021 at 07:29 | Report abuse | Reply
  30. JnscCrulk

    fed ex overnight delivery viagra viagra 20 mg from united kingdom viagra daily http://erectilejyzd.com/index.php?called=terms – buy viagra tadalafil ’

    January 31, 2021 at 07:44 | Report abuse | Reply
  31. NgscZisse

    20 mg viagra daily how to get a viagra prescription online how to get real viagra http://canadianpharmacy-yy.com/Fitness/how-to-get-a-six-pack.html – viagra generic ’

    February 1, 2021 at 00:09 | Report abuse | Reply
  32. FmnfEncox

    buy cialis online from canada cialis nz is generic cialis safe https://impotencecdny.com/info/history.php – germany cialis professional ’

    February 1, 2021 at 01:50 | Report abuse | Reply
  33. Benedict Hayes

    This is a very interesting article. Please, share more like this!


    February 1, 2021 at 16:40 | Report abuse | Reply
  34. Kuikseelt

    best online sites for viagra generic viagra with next day delivery generic viagra

    February 4, 2021 at 19:23 | Report abuse | Reply
  35. FqhhEncox

    drugs online discount pharmacy online pharmacy online cheap

    February 5, 2021 at 13:04 | Report abuse | Reply
  36. JbbvEncox

    walmart pharmacy online prescription drugs prices try our ed pack

    February 6, 2021 at 07:26 | Report abuse | Reply
  37. JbnbCrulk

    discount pharmacy board of pharmacy canada drugs

    February 6, 2021 at 15:04 | Report abuse | Reply
  38. zortilonrel

    Hello, you used to write fantastic, but the last few posts have been kinda boringK I miss your super writings. Past few posts are just a little bit out of track! come on!


    February 7, 2021 at 04:08 | Report abuse | Reply
  39. FvfcZisse

    free viagra canada viagra pyschological buy online viagra

    February 7, 2021 at 17:14 | Report abuse | Reply
  40. NncsZisse

    buy 100 ml viagra cheap drugs online cheap generic viagra 100mg

    February 7, 2021 at 22:20 | Report abuse | Reply
  41. KbcxMile

    walmart pharmacy viagra prescription drugs from canada online buy prescription drugs online

    February 8, 2021 at 05:47 | Report abuse | Reply
  42. AhkdEncox

    medication costs highest rated canadian pharmacies pharmacy northwest canada

    February 8, 2021 at 20:10 | Report abuse | Reply
  43. https://dr-goz-peter-ugyved.business.site/

    Simply wanna remark on few general things, The website style and design is perfect, the subject matter is really great : D.


    February 9, 2021 at 03:10 | Report abuse | Reply
  44. AqcfTeneseelt

    daily use cialis cost cialis costco price cialis 20mg

    February 9, 2021 at 11:02 | Report abuse | Reply
  45. Kbbfseelt

    viagra for sale in ireland http://kloviagrli.com/ questions about viagra

    February 11, 2021 at 21:53 | Report abuse | Reply
  46. FqbbEncox

    cash advance loans memphis tn everest cash advance mailing address cash loans low income

    February 12, 2021 at 10:01 | Report abuse | Reply
  47. LabxEncox

    does cialis lose potency modello ricetta cialis claritin d and cialis

    February 13, 2021 at 04:26 | Report abuse | Reply
  48. JbbnEncox

    cialis sales in canada viagra et cialis en meme temps О±ОіОїПЃО± cialis ПѓП„О·ОЅ ОµО»О»О±ОґО±

    February 13, 2021 at 09:14 | Report abuse | Reply
  49. JbnvCrulk

    stop payday loans taking money my account payday loans no bank account reno nv quick cash loan in davao city

    February 13, 2021 at 14:51 | Report abuse | Reply
  50. KvaxMile

    payday loans 23228 payday loans in binghamton ny where to get a payday loan fast

    February 15, 2021 at 14:13 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10

Leave a Reply to Mom of three


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.