 |
|
|
|
|
September 22nd, 2010
08:35 AM ET
Is the inability of cancer patients to eat a concern?Every weekday, a CNNHealth expert doctor answers a viewer question. On Wednesdays, it's Dr. Otis Brawley, chief medical officer at the American Cancer Society. Question asked by Steve Snodgrass, Bowling Green, Kentucky I wanted to see what your experts thought about cancer/chemotherapy patients and protein malnutrition. I have read it leads to as many as 45 to 50 percent of cancer deaths. Is the inability of cancer patients to eat of major concern to cancer health care providers? Thank you. Expert Answer You ask an important question about a devastating problem. Cachexia is a condition in which the body consumes excess energy. There is accelerated loss of fat stores and then consumption of proteins such as skeletal muscle. Cachexia is best known as a disease of cancer patients, but it is seen in patients with chronic infection, AIDS, heart failure, rheumatoid diseases and chronic obstructive pulmonary disease. Nearly half of patients with cancer that has spread to organs other the original site of disease (metastatic disease) have cachexia. Loss of appetite or anorexia is often associated with cachexia, especially cachexia of malignancy. Contrary to what many think, this is not a disease caused by starvation. The loss in weight and body mass is driven by a metabolic disease manifested by increased energy consumption. As a result aggressive feeding and caloric replacement are not adequate treatments. Extremely aggressive efforts are to be discouraged. There are studies to suggest that forced tube feeding or intravenous feeding (known as hyperalimentation) can actually increase risk of infection and death. Cachectic patients generally do not respond well to anti-cancer therapies. In one National Cancer Institute sponsored study, weight loss of greater than 5% from baseline was a predictor of poor outcome independent of cancer stage, type of cancer and patient performance status. Performance status is a rating of a patient's ability to walk and independently care for ones activities of daily living such as dressing oneself or hygiene. Studies demonstrate that cachexia is the direct cause of death in a small number of cancer patients (1 to 2 percent). This is akin to the body running out of fuel or extreme malnutrition. More commonly the person has lost a great deal of immune function and becomes susceptible to infection or cachexia can lead to metabolic disorders that can cause heart rhythm disturbances. There are no good estimates as to how often this occurs. Cancer cachexia appears to be caused by chemicals given off by the tumor or by the patient's immune system that is trying to combat the tumor. These chemicals are called cytokines. Some cytokines have also been found to cause depression which can also of course cause loss of appetite which worsens the condition. When there is effective treatment of the cancer, symptoms of cachexia decrease. A number of agents have been studied, not as treatment of the cancer, but as a treatment of the condition known as cachexia of malignancy. These include melatonin, thalidomide, cannabinoids, and androgenic steroids. Only the corticosteroids, such as dexamethasone, and the progestational agents, such megesterol acetate, have proven of benefit in treatment of the loss of appetite. While a number of studies show corticosteroids and progestational agents cause an increase in appetite and even weight gain, these studies have not shown that they improve quality of live or survival. soundoff (1,148 Responses)« Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Next »Leave a Reply to Flossie
Next entry »TEDMED: What do your genes say about you?
|
  About this blog
Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.
 |
|
|
|
You ought to take part in a contest for one of the highest quality blogs
on the internet. I am going to recommend this web site! https://school.mosreg.ru/soc/moderation/abuse.aspx?link=https://trmedya.co/
twitter homework help pay for uni essays boston ma resume writing service executive resume writing service san jose
I would like to thank you for the efforts you've put in writing this website. I am hoping to check out the same high-grade blog posts from you later on as well. In truth, your creative writing abilities has inspired me to get my own, personal website now 😉
http://zooboard.ru/user/profile/14175
I love looking through an article that will make people think. Also, thank you for allowing me to comment!
http://driver.com.ru/user/p7iibhv171
afl writing service amibroker essay the help movie database homework help transfer application essay help
help write a thesis statement for me narrative essay about community service british gas service plan telephone homework help paris
cyclosporine 100 mg cyclomune
Not many writers with proper expertise of the topics they blog about.
https://www.sfgate.com/cannabis-paid/article/best-cbd-oil-for-dogs-15812674.php
homework problems help band 6 world order essay pay for math homework online business plan for service station
I'm extremely pleased to find this page. I wanted to thank you for ones time for this particularly fantastic read!! I definitely loved every bit of it and i also have you bookmarked to see new things in your site.
http://w-w-b.net.ua/user/canoesilver34/
buy essay canada i forgot to do my essay can someone do my coursework for me do my homework app
Very good info. Lucky me I came across your blog by chance (stumbleupon). I have bookmarked it for later!
http://www.szltgd.com/space-uid-1143999.html
chloroquin https://chloroquineorigin.com/ – cloroquine chloroquine phosphate brand name aralen buy https://chloroquineorigin.com/
xml homework help management essay writing service desire to help others essay homework help trigonometry
cyclosporine eye drops cyclosporine medication
You have made some really good points there. I looked on the internet to find out more about the issue and found most individuals will go along with your views on this website.
https://www.chilterntraveller.co.uk/members/baccarat0sockliquid23/activity/1149420/
Different kinds of stainless-steel are produced depending on the amount of nickel and chromium in the alloy. Chrome, brief for chromium,
https://www.ted.com/profiles/27978397
buy your essay community service essay hook bike sharing programs essay elementary homework help online
https://chloroquineorigin.com/ hydroxychloroquine coronavirus clonidine chloroquine tablets chloroquine prophylaxis
Cyclomune eye drops 0.05% cyclosporine for humans
Aw, this was an exceptionally nice post. Finding the time and actual effort to generate a top notch articleÖ but what can I sayÖ I hesitate a whole lot and never seem to get nearly anything done.
https://diigo.com/0k5d6r
hydroxychloroquine coronavirus https://chloroquineorigin.com/ – clozapine arechin aralen phosphate chloroquine phosphate buy aralen
The only thing I lament is not having found your blog before.
https://gliderclerk7.bladejournal.com/post/2021/05/22/Why-People-Read-Fitness-Equipment-Reviews
First off I want to say terrific blog! I had a quick
question in which I'd like to ask if you don't mind.
I was interested to know how you center yourself and clear
your thoughts prior to writing. I have had a difficult time clearing my mind in getting my thoughts out there.
I truly do enjoy writing but it just seems like
the first 10 to 15 minutes are lost simply just trying to figure out how to begin. Any ideas
or tips? Cheers!
My web site microsoft certification books, Leonida,
Hiya! I know this is kinda off topic however , I'd figured I'd ask. Would you be interested in trading links or maybe guest authoring a blog article or vice-versa? My website discusses a lot of the same topics as yours and I think we could greatly benefit from each other. If you happen to be interested feel free to shoot me an email. I look forward to hearing from you! Superb blog by the way!
https://ultrapedia.org/wiki/index.php/User:JacquieBaber906
chloroquine for lupus where to buy aralen aralen uk chloroquine phosphate brand name https://chloroquineorigin.com/
You've made some really good points there. I looked on the net for more information about the issue and found most individuals will go along with your views on this site.
http://www.dylshou.com/home.php?mod=space&uid=40999
Your Online Metal Marketplace In Texas With Lowest Prices, Guaranteed. Countless Steel Items Available, Custom or Stock. Call Our Experts, Shop Steel Now
https://www.weddingbee.com/members/lorentzenramirez10
You made some good points there. I looked on the net for additional information about the issue and found most people will go along with your views on this website.
http://goodpeoplecoin.com/forums/user/b1kypmj878/
A provider buildup in Scotland requires one to feature a 'stakeholder'
provision with the Record as well as Articles of
Association. This condition mentions that all shareholders
that will definitely make a offered variety of equity contributions
are actually needed to authorize their labels as stakeholders to the backing of the
business. This aids to give reliability to the business as all stakeholders are going to know specifically what funds are readily available
for their requirements without must ask for financing coming from third parties.
If your business were actually to go under throughout the
term of the Record as well as Contents of Association, then it would certainly
need investors to begin the procedure of seeking a brand-new partner
to take over the business. Therefore, the
visibility of the stakeholder stipulation provides security for all
stakeholders.
If you desire to combine a organization, there are a lot of solicitors
that specialize in business rule that can assist you ready up and
develop your company. Company rule possesses a
variety of intricate conditions and also clauses
that require to be recognized carefully in order to ensure you perform not crack any laws or even laws.
A lawyer is going to have the ability to assist you via every action of the
method from the conception of your firm by means
of to its own consolidation. Most solicitors in Edinburgh
exclusively manage corporations, collaborations, limited
liability alliances, restricted collaborations, partnership shares and leaves.
However, there are actually various other solicitors
that have the ability to encourage you on the format of your Record and
Articles of Association.
cyclomune cyclomune eye drops 1%
What's up to every one, the contents existing at this web page
are in fact awesome for people experience, well, keep up the good work fellows.
https://tadalafilww.com/ where to buy cialis without prescription https://tadalafilww.com/ – tadalafil without a doctor prescription lowest price cialis
combigan combigan generic prices
buy generic cialis online with mastercard tadalafil liquid buy generic cialis online with mastercard cialis without a prescription https://tadagatadalafil.com/
https://tadalafilww.com/ tadalafil generic where to buy https://tadacipetadalafil.com/ – tadalafil generic prescription tadalafil online
buy brimonidine online combigan bottle sizecombigan
generic cialis online fast shipping tadalafil daily online generic cialis tadalafil https://tadalafilol.com/
tadalafil online https://cttadalafil.com/ cheapest tadalafil cost buy cialis generic cialis tadalafil
Cyclomune eye drops 0.05% buy cyclosporine online
https://apcalisetadalafil.com/ best price usa tadalafil https://tadacipetadalafil.com/ – tadalafil generic where to buy cheap generic cialis for sale
generic tadalafil from uk generic tadalafil from uk where to buy generic cialis online safely buy cialis pills https://tadacipetadalafil.com/
When someone writes an piece of writing he/she keeps the
image of a user in his/her brain that how a user can know it.
Thus that's why this post is perfect. Thanks!
https://tadalafilol.com/ side effects for tadalafil side effects of tadalafil cialis cost where to buy cialis without prescription
brimonidine generic brimonidine use
cheap generic cialis for sale cheapest tadalafil cost buy tadalis where to buy generic cialis online safely https://tadacipetadalafil.com/
cheap cialis pills for sale tadalafil cost walmart side effects for tadalafil https://cttadalafil.com/
https://tadagatadalafil.com/ cost of cialis https://tadacipetadalafil.com/ – tadalafil generic where to buy cialis cost
https://apcalisetadalafil.com/ tadalafil brands https://tadacipetadalafil.com/ – generic tadalafil from uk cheap generic cialis for sale
combigan brimonidine