home
RSS
September 21st, 2010
10:23 AM ET

How can I stop using Paxil without the side effects?

Every weekday, a CNNHealth expert doctor answers a viewer question. On Tuesdays, it's Dr. Charles Raison, an associate professor of psychiatry and behavioral sciences at Emory University, and an expert in the mind-body connection for health.

Question asked by Sharon Reynolds of Tampa, Florida: I have been taking 10 mg of Paxil for nine years. I would like to get off of it but have heard of the many side effects associated with stopping it. Brain "buzzes" and various other frightening possibilities.

How can I stop Paxil without those side effects? I started taking it after a complete hysterectomy that resulted in extreme anxiety.

Expert answer: Dear Sharon,

There is good news and bad news about your situation.

The good news is that only about 20 percent of patients who take antidepressants experience these type of withdrawal symptoms when they discontinue the medications, and when experienced, these symptoms are usually mild and resolve in a week or two.

The bad news is that you have two risk factors for experiencing an antidepressant withdrawal syndrome. First you have been on your antidepressant for an extended period. Second, you are taking Paxil (generic paroxetine) which - because of its short "half-life" in the body - is especially notorious for causing withdrawal problems.

There are two very important things you can do to reduce your risk of having the type of symptoms you describe.

First, you should work closely with your health care provider. Second, you should never just stop the medication.

Probably the all-time best way to experience antidepressant withdrawal is to just suddenly stop the medication. Doing this is a shock to the nervous system, which has adjusted its neurotransmitter release based on the presence of the antidepressant.

In the case of medications like Paxil that affect serotonin, we believe most of the withdrawal symptoms are related to a sudden increase in serotonin activity for which body and brain are not prepared.

The first thing a good clinician will do is closely examine whether stopping the Paxil is a good idea in the first place. If you have been on the medication for 10 years and are emotionally stable, it might be the right thing to do.

Even if it makes sense to do this, a good clinician will be carefully watching, not just for withdrawal symptoms, but also for any sign that the psychiatric condition that prompted you to take the medication in the first place isn't coming back.

The most common symptoms of a Paxil withdrawal syndrome are feeling like you have the flu, often in combination with dizziness, sensory disturbances (like the buzzing you describe) and anxiety/agitation.

The trick to lowering your chances of having these symptoms is to reduce the dose of the antidepressant as slowly as possible. For people who are really sensitive it can take months to get off an antidepressant slowly enough to avoid withdrawal symptoms.

But remember that most people can stop an antidepressant cold and won't have symptoms. Whether you would be similarly fortunate or more unlucky is probably not a question you should test out. Rather, I recommend starting to work with your clinician to slowly lower the dose. If you feel fine you might try lowering the dose more rapidly as it feels comfortable.


soundoff (1,620 Responses)
  1. 24 hour pharmacy near me

    http://infotiger.com/addurl.html?url=https://cateringbusinessplans.com

    June 14, 2021 at 17:32 | Report abuse | Reply
  2. pizza delivery near me

    Way cool! Some extremely valid points! I appreciate you writing this article and also the rest of the site is also really good.

    http://mitsui-shopping-park.com/lalaport/iwata/redirect.html?url=romeomotorsports.com/

    June 14, 2021 at 18:11 | Report abuse | Reply
  3. delivery near me

    Very good info. Lucky me I came across your website by accident (stumbleupon). I've book marked it for later!

    http://www.portuguese.myoresearch.com/?URL=https://www.socialmediacoversmadeforyou.com

    June 14, 2021 at 18:58 | Report abuse | Reply
  4. RV Repair Orange County California

    Very nice article. I absolutely love this site. Stick with it!

    https://www.herna.net/cgi/redir.cgi?www.ocrvcenter.com/rv-repair-shop-cerritos-california

    June 14, 2021 at 21:32 | Report abuse | Reply
  5. RV Repair Shops Near Me Now

    I was very pleased to uncover this site. I wanted to thank you for ones time due to this fantastic read!! I definitely savored every bit of it and I have you saved as a favorite to check out new stuff in your website.

    https://www.dartn.de/redirect/?url=https://ocrvcenter.com/rv-repair-shop-lemon-grove-california

    June 14, 2021 at 22:17 | Report abuse | Reply
  6. Sprinter Repair Shops Near Me

    Howdy, There's no doubt that your site may be having browser compatibility issues. Whenever I take a look at your site in Safari, it looks fine however, when opening in IE, it has some overlapping issues. I simply wanted to give you a quick heads up! Besides that, great site!

    https://www.mf-shogyo.co.jp/link.php?url=https://ocrvcenter.com/motorhome-technician-near-me

    June 14, 2021 at 22:26 | Report abuse | Reply
  7. RV Repair Near Me

    You're so interesting! I don't think I have read anything like that before. So good to discover someone with some original thoughts on this subject matter. Really.. many thanks for starting this up. This site is something that's needed on the internet, someone with a little originality!

    http://atari.org/links/frameit.cgi?footer=YES&back=https://www.ocrvcenter.com/shuttle-truck-collision-repair-shop-near-me/

    June 14, 2021 at 22:43 | Report abuse | Reply
  8. Nearby RV Repairs

    http://www.horizoninteractiveawards.com/index.php?URL=https://ocrvcenter.com/rv-maintenance-near-me-2

    June 14, 2021 at 23:35 | Report abuse | Reply
  9. RV Repair San Clemente California

    Hi there! I could have sworn Iíve visited this site before but after browsing through many of the articles I realized itís new to me. Anyways, Iím definitely pleased I discovered it and Iíll be book-marking it and checking back frequently!

    https://www.blackfive.net/__media__/js/netsoltrademark.php?d=ocrvcenter.com/rv-countertop-repair-near-me

    June 14, 2021 at 23:48 | Report abuse | Reply
  10. RV Repair Shop

    https://scanmail.trustwave.com/?c=8510&d=4qa02KqxZJadHuhFUvy7ZCUfI_2L10yeH0EeBz7FGQ&u=https://ocrvcenter.com/construction-truck-collision-repair-shop-near-me/

    June 15, 2021 at 00:47 | Report abuse | Reply
  11. RV Repairs Nearby

    An interesting discussion is definitely worth comment. I do think that you ought to publish more about this subject, it might not be a taboo matter but typically folks don't discuss such subjects. To the next! All the best!!

    http://freedback.com/thank_you.php?u=https://ocrvcenter.com/rv-repair-shop-granada-hills-california/

    June 15, 2021 at 02:33 | Report abuse | Reply
  12. RV Repair Orange County

    https://friscowebsites.com/Redirect.aspx?destination=https://www.ocrvcenter.com/rv-leak-repair-near-me

    June 15, 2021 at 03:01 | Report abuse | Reply
  13. RV Repair Santa Ana

    http://www.galter.northwestern.edu/exit?url=http://www.game-mun.com/forum/index.php?topic=2215.msg120102

    June 15, 2021 at 03:23 | Report abuse | Reply
  14. Camper Repairs Near Me

    Iím impressed, I must say. Seldom do I come across a blog thatís both equally educative and interesting, and without a doubt, you've hit the nail on the head. The problem is something that too few folks are speaking intelligently about. I am very happy I found this during my hunt for something relating to this.

    https://neurostar.com/en/redirect.php?url=http://www.ocrvcenter.com/rv-repair-shop-chino-hills-california/

    June 15, 2021 at 03:53 | Report abuse | Reply
  15. 먹튀커뮤니티

    This design is steller! You most certainly know how to keep a reader
    amused. Between your wit and your videos, I was almost moved to start my own blog (well, almost...HaHa!) Great job.

    I really loved what you had to say, and more than that,
    how you presented it. Too cool!

    June 15, 2021 at 04:13 | Report abuse | Reply
  16. Camper Repairs Near Me

    I would like to thank you for the efforts you have put in writing this blog. I really hope to view the same high-grade content by you in the future as well. In truth, your creative writing abilities has motivated me to get my own, personal blog now 😉

    http://georgewbushlibrary.smu.edu/exit.aspx?url=http://produccionestoro.com/revealing-painless-solutions-in-top-essay-writing-reviews-reviewingwriting/

    June 15, 2021 at 04:27 | Report abuse | Reply
  17. Camper Repair Shop Near Me

    http://sutemos.wip.lt/redirect.php?url=http://www.ocrvcenter.com/rv-repair-shop-carlsbad-california

    June 15, 2021 at 04:54 | Report abuse | Reply
  18. RV Repair Fountain Valley

    &PageName=login.asp

    June 15, 2021 at 05:55 | Report abuse | Reply
  19. Camper Repair Shop Near Me

    http://jp.local.com/__media__/js/netsoltrademark.php?d=www.ocrvcenter.com/rv-repair-shop-corona-california/

    June 15, 2021 at 07:52 | Report abuse | Reply
  20. RV Repair Huntington Beach

    https://nagano.visit-town.com/functions/external_link?www.ocrvcenter.com/rv-plumbing-repair-near-me

    June 15, 2021 at 08:14 | Report abuse | Reply
  21. RV Repair Seal Beach

    This web site really has all the information I needed about this subject and didnít know who to ask.

    https://www.cassinausa.com/__media__/js/netsoltrademark.php?d=www.ocrvcenter.com/rv-repair-shop-castaic-californiacity-temp-wireframe

    June 15, 2021 at 08:47 | Report abuse | Reply
  22. RV Repairs Near Me

    http://sherlock.scribblelive.com/r?u=www.hootnholler.net/apostle-islands-camping-reopens-for-2021-superior-telegram/

    June 15, 2021 at 08:51 | Report abuse | Reply
  23. Camper Repair Shop Near Me

    http://offers.sidex.ru/stat_ym_new.php?redir=ocrvcenter.com/rv-repair-shop-perris-california&hash=1577762

    June 15, 2021 at 09:42 | Report abuse | Reply
  24. RV Repair Near My Location

    https://localbusiness.houmatoday.com/__media__/js/netsoltrademark.php?d=http://ocrvcenter.com/rv-repair-shop-noho-arts-district-california/

    June 15, 2021 at 10:35 | Report abuse | Reply
  25. RV Repair Shops Near Me Now

    Aw, this was a really good post. Taking a few minutes and actual effort to make a good articleÖ but what can I sayÖ I procrastinate a lot and never manage to get nearly anything done.

    http://salesnews.qantas.com/public/m/closed?msLRR=http://12rex.com/foto_descansillo-big/

    June 15, 2021 at 11:09 | Report abuse | Reply
  26. RV Repair Orange County

    http://affiliate.joomla-monster.com/idevaffiliate.php?id=789&url=http://qdsinocrown.com/?p=1397

    June 15, 2021 at 12:43 | Report abuse | Reply
  27. RV Repair Shops Near Me

    https://vladinfo.ru/away.php?url=https://ocrvcenter.com/national-general-rv-collision-repair-shop-near-me/

    June 15, 2021 at 13:30 | Report abuse | Reply
  28. RV Repair California

    Good post. I learn something new and challenging on blogs I stumbleupon everyday. It will always be useful to read through articles from other writers and practice something from other sites.

    https://www.paeria.cat/ang/ajuntament/noticies.asp?Detall=True&IdNoticia=21087&Dia=-1&Mes=-1&Any=2014&IdDepartament=-1&Consulta=False&PaginaAnterior=http://ocrvcenter.com/rv-repair-shop-santa-ana-california/

    June 15, 2021 at 15:07 | Report abuse | Reply
  29. RV Repair Huntington Beach

    I'd like to thank you for the efforts you've put in writing this site. I'm hoping to view the same high-grade content from you in the future as well. In fact, your creative writing abilities has encouraged me to get my own blog now 😉

    http://directory.lufkindailynews.com/__media__/js/netsoltrademark.php?d=ocrvcenter.com/rv-repair-shop-palmdale-california

    June 15, 2021 at 15:31 | Report abuse | Reply
  30. Camper Repairs Near Me

    Very good article. I definitely love this site. Keep it up!

    http://funny-games.ws/bookmark.php?url=http://www.ocrvcenter.com/testimonials

    June 15, 2021 at 20:23 | Report abuse | Reply
  31. RV Repairs Nearby

    Good info. Lucky me I came across your website by accident (stumbleupon). I've book marked it for later!

    https://go.xscript.ir/index.php?url=ocrvcenter.com/rv-repair-shop-hermosa-beach-california

    June 15, 2021 at 20:34 | Report abuse | Reply
  32. RV Repairs Near My Location

    Good article! We will be linking to this great post on our site. Keep up the great writing.

    http://sv.paltalk.com/client/webapp/client/External.wmt?url=http://ocrvcenter.com/national-general-rv-collision-repair-shop-near-me/

    June 15, 2021 at 22:11 | Report abuse | Reply
  33. RV Repair Huntington Beach

    This is a really good tip particularly to those new to the blogosphere. Short but very precise informationÖ Appreciate your sharing this one. A must read article!

    http://yellowpages.uticaod.com/__media__/js/netsoltrademark.php?d=http://ocrvcenter.com/rv-repair-shop-los-angeles-california/

    June 15, 2021 at 23:11 | Report abuse | Reply
  34. RV Repairs Near Me

    Itís nearly impossible to find well-informed people about this subject, however, you seem like you know what youíre talking about! Thanks

    https://herna.net/cgi/redir.cgi?ocrvcenter.com/class-6-truck-collision-repair-shop-near-me

    June 15, 2021 at 23:22 | Report abuse | Reply
  35. RV Repair Santa Ana

    https://es.paltalk.com/client/webapp/client/External.wmt?url=https://www.ocrvcenter.com/cascade-collision-repair-shop-near-me

    June 15, 2021 at 23:23 | Report abuse | Reply
  36. Nearby RV Repairs

    https://sfwater.org/redirect.aspx?url=http://www.ocrvcenter.com/motorhome-dent-repair-near-me/

    June 16, 2021 at 03:15 | Report abuse | Reply
  37. Camper Repair Near Me

    https://aarss.com/redir.php?siteref=&aarsslink=http://www.ocrvcenter.com/camper-collision-repair-shop-near-me

    June 16, 2021 at 03:26 | Report abuse | Reply
  38. RV Repair Shop Near My Location

    http://www.saco.se/EPiServerMail/Public/CheckLink.aspx?url=ocrvcenter.com/rv-repair-shop-redondo-beach-california/

    June 16, 2021 at 03:37 | Report abuse | Reply
  39. RV Repair Near My Location

    http://www.boosterblog.com/vote-864130-668401.html?adresse=https://www.ocrvcenter.com/rv-repair-shop-san-marcos-california&

    June 16, 2021 at 03:41 | Report abuse | Reply
  40. Camper Repair Shops Near Me

    http://www.fms.treas.gov/fmsweb/disclaimer.jsp?ciURL=http://www.ingenieurleistungenreiter.de/index.php?option=com_phocaguestbook&view=phocaguestbook&id=1&Itemid=4&limitstart=29200

    June 16, 2021 at 05:13 | Report abuse | Reply
  41. Camper Repair Shop Near Me

    https://www.etis.ford.com/externalURL.do?url=https://ingenieurleistungenreiter.de/index.php?option=com_phocaguestbook&view=phocaguestbook&id=1&Itemid=4&t=740&limitstart=66020

    June 16, 2021 at 05:26 | Report abuse | Reply
  42. Nearby RV Repairs

    I used to be able to find good info from your blog articles.

    https://weblib.lib.umt.edu/redirect/proxyselect.php?url=https://cien-byarhair.com/archives/11035

    June 16, 2021 at 05:38 | Report abuse | Reply
  43. RV Repairs Near My Location

    I really like reading through a post that can make men and women think. Also, thanks for permitting me to comment!

    https://my.volusion.com/TransferLogin.aspx?HostName=stclairbowl.com/dscn7423/

    June 16, 2021 at 06:53 | Report abuse | Reply
  44. RV Repair Shop Near My Location

    http://www.historyhub.history.gov/external-link.jspa?url=https://ocrvcenter.com/rv-repair-shop-santa-clarita-california

    June 16, 2021 at 07:02 | Report abuse | Reply
  45. Camper Repairs Near Me

    https://www.cross-a.net/go_out.php?url=ocrvcenter.com/rv-repair-shop-loma-linda-california/

    June 16, 2021 at 10:52 | Report abuse | Reply
  46. RV Repair Huntington Beach

    http://www.faseb.org/pdfviewer?loadthis=http://www.ocrvcenter.com/rv-repair-shop-compton-california

    June 16, 2021 at 10:59 | Report abuse | Reply
  47. RV Repair Orange County California

    Your style is so unique compared to other people I have read stuff from. Many thanks for posting when you have the opportunity, Guess I will just book mark this blog.

    https://www.cbts2.thischurch.org/mod/admin/view-image.php?i=/share/mod_news_images/2767.jpg&ru=https://www.ocrvcenter.com/toy-hauler-trailer-collision-repair-shop-near-me/

    June 16, 2021 at 11:49 | Report abuse | Reply
  48. Sprinter Repair Costa Mesa

    https://bibliopam.ec-lyon.fr/fork?http://radiobanadir.com/the-definitive-guide-to-marketing-your-business-on-instagram/comment-page-31/

    June 16, 2021 at 12:16 | Report abuse | Reply
  49. rest area near me

    http://stadt-gladbeck.de/ExternerLink.asp?ziel=www.ocrvcenter.com/

    June 16, 2021 at 13:49 | Report abuse | Reply
  50. toyota near me

    Hi there! This post could not be written any better! Reading through this article reminds me of my previous roommate! He constantly kept talking about this. I am going to forward this post to him. Fairly certain he will have a good read. Thanks for sharing!

    https://www.kaimaluhawaii.com/__media__/js/netsoltrademark.php?d=www.ocrvcenter.com

    June 16, 2021 at 14:03 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32

Leave a Reply to Van Repair


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.