September 17th, 2010
05:00 PM ET

FDA reviews diabetes drug Actos

Another diabetes drug is under the Food and Drug Administration's microscope amid safety concerns. On Friday, the agency announced preliminary five-year data shows Actos can increase the risk of bladder cancer in patients using the drug long-term.

Pioglitazone, marketed as Actos, is one of two drugs used to control blood sugar in diabetics.  The data are from a 10-year study by the manufacturer Takeda Pharmaceuticals of San Diego.  The early results did not show an overall link between use and the risk of bladder cancer, but taking the drug for a long time or in high doses may increase the risk, according to the study.

In July a FDA advisory committee looked at whether to pull GlaxoSmithKline's diabetes drug  Avandia off the market because of concerns it increased the risk of heart attack and stroke. 

The committee was split on whether to pull the drug– 12 of the 33 members voted to withdraw Avandia from the market, while 20 voted to allow it to remain with enhanced restrictions and rigorous black box warning labels.  The agency says it  has no data linking Avandia to bladder cancer.  Actos and Avandia are in the same class of drugs.

A FDA statement said the review is ongoing, and that it "has not concluded that Actos increases the risk of bladder cancer."   Patients with any concerns about Actos should not stop taking the drug but talk to their doctor, the FDA advised.

soundoff (627 Responses)
  1. RV Repairs Nearby

    Your style is unique compared to other people I have read stuff from. I appreciate you for posting when you have the opportunity, Guess I'll just bookmark this blog.


    June 28, 2021 at 13:42 | Report abuse | Reply
  2. RV Repair San Clemente California


    June 28, 2021 at 17:57 | Report abuse | Reply
  3. Sprinter Repair Shop Near Me


    June 28, 2021 at 20:10 | Report abuse | Reply
  4. Rv Windshield Replacement


    June 28, 2021 at 21:36 | Report abuse | Reply
  5. RV Repair Seal Beach


    June 29, 2021 at 01:39 | Report abuse | Reply
  6. Rv Collision Repair Shop Near Me

    I couldnít resist commenting. Perfectly written!


    June 29, 2021 at 03:12 | Report abuse | Reply
  7. High Roof Sprinter Repair Panels

    After I originally left a comment I appear to have clicked the -Notify me when new comments are added- checkbox and from now on each time a comment is added I recieve 4 emails with the exact same comment. There has to be an easy method you can remove me from that service? Kudos!


    June 29, 2021 at 04:29 | Report abuse | Reply
  8. RV Repair Around Me


    June 29, 2021 at 04:46 | Report abuse | Reply
  9. Nearest RV Repair

    Great blog you've got here.. Itís difficult to find excellent writing like yours nowadays. I really appreciate individuals like you! Take care!!


    June 29, 2021 at 07:16 | Report abuse | Reply
  10. RV Repair Near My Location


    June 29, 2021 at 07:46 | Report abuse | Reply
  11. RV Repair Santa Ana

    Everything is very open with a really clear clarification of the issues. It was really informative. Your website is very useful. Thanks for sharing!


    June 29, 2021 at 07:48 | Report abuse | Reply
  12. Mercedes Sprinter Van 2015 3500 Repair

    Everything is very open with a very clear clarification of the challenges. It was truly informative. Your website is extremely helpful. Thanks for sharing!


    June 29, 2021 at 08:00 | Report abuse | Reply
  13. RV Repair Shops Near Me Now

    Great post! We are linking to this great post on our website. Keep up the great writing.


    June 29, 2021 at 11:39 | Report abuse | Reply
  14. Camper Repair Shop Near Me


    June 29, 2021 at 14:24 | Report abuse | Reply
  15. RV Repairs Near Me

    Excellent post. I am facing many of these issues as well..


    June 29, 2021 at 18:32 | Report abuse | Reply
  16. RV Repair Mission Viejo


    June 29, 2021 at 21:06 | Report abuse | Reply
  17. Sprinter Van Upgrades


    June 29, 2021 at 22:39 | Report abuse | Reply
  18. RV Repairs Near Me


    June 30, 2021 at 03:20 | Report abuse | Reply
  19. Van Dent Repair Shop Near Me


    June 30, 2021 at 05:04 | Report abuse | Reply
  20. Authorized Dodge Sprinter Repair


    June 30, 2021 at 05:18 | Report abuse | Reply
  21. RV Repair Shops Near Me Now

    This blog was... how do I say it? Relevant!! Finally I've found something which helped me. Thanks!


    June 30, 2021 at 06:55 | Report abuse | Reply
  22. Sprinter Repair Orange County


    June 30, 2021 at 08:56 | Report abuse | Reply
  23. RV Repair Huntington Beach


    June 30, 2021 at 09:48 | Report abuse | Reply
  24. RV Repair Shops Near My Location

    You're so interesting! I do not believe I've read something like this before. So great to discover somebody with a few genuine thoughts on this subject. Really.. thank you for starting this up. This site is one thing that is required on the internet, someone with a bit of originality!


    June 30, 2021 at 10:24 | Report abuse | Reply
  25. RV Repair Garden Grove


    June 30, 2021 at 10:31 | Report abuse | Reply
  26. KIU

    Great goods from you, man. I have understand your stuff previous to and you are just too magnificent.

    I actually like what you've acquired here, really like what you are saying and
    the way in which you say it. You make it entertaining and you still take care of to keep it smart.
    I can not wait to read much more from you. This is
    actually a wonderful web site.

    June 30, 2021 at 10:47 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13

Post a comment


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.