home
RSS
September 13th, 2010
12:02 AM ET

Study: Men with low initial PSA levels less likely to develop prostate cancer

Men with low PSA levels from a baseline blood test were less likely to develop prostate cancer compared to men whose baseline PSA levels were high, according to a new study.

The simple test may be a strong predictor of who will benefit from future screening and treatment for prostate cancer, according to the study published Monday in the journal Cancer.

More than 85,000 men, ages 55 to 74, with no previous prostate cancer history were the subjects of the study. The authors found that in order to save one life, they needed to investigate almost  25,000 men with low PSA levels but only 133 men with high ones. Similarly, they needed to treat 724 men who had low PSA levels to save one life but only 60 men whose levels were higher.

PSA, or prostate-specific antigen, is a protein found in prostate cancer tissue. When that tissue breaks down, the protein seeps into the bloodstream. The heavier the presence of PSA in the blood, the more likely prostate cancer will be dangerous and require some type of treatment, said Dr. Otis Brawley, Chief Medical Officer at American Cancer Society and a contributor to CNNHealth.com.

But aren't all cancers bad, even if a man's PSA level is low?

"There are a large number of prostate cancers that don't need to be treated because they're not a health threat to the man who has them," explained Brawley.  That makes guidelines for screenings more difficult to set.

The American Cancer Society encourages men to work with their doctors to learn about the test's benefits and risks before making an informed personal decision around age 50.   Research has not yet proven that the potential benefits of testing outweigh the harms of testing and treatment, explains the organization.

The American Urology Association recommends baseline screening for men at age 40 with future screenings determined in conjunction with the patient's doctor.

"This can't be done in a vacuum," said Dr. J. Brantley Thrasher, spokesman for the American Urology Association and the William L. Balk Chair of the Department of Urology at the University of Kansas. "We need to let [patients] know this is an imperfect marker, but we're getting data that may help us in the future."

It's difficult to accept the idea that you could have prostate cancer that doesn't need to be treated and could be left alone with no harm, while other men have aggressive and deadly prostate cancers.  Brawley, who chooses not to be screened, thinks this is why most men get PSA tests regularly, despite the many risks associated treatment.

"By choosing to get screened, there is a guaranteed increase in diagnosis... but there is only a potential decrease in death," said Brawley.

Some of the risks of treatment include impotence, incontinence and bowel injury.

Still, Thrasher says the importance of the PSA blood test should not be diminished. He tells his patients to get regular screenings every other year or every three years after their initial test.

"I believe knowledge is power to some extent," said Thrasher. "It's risks versus benefits... and each decision point is a fork in the road where [me and patients] have to have a discussion."


soundoff (708 Responses)
  1. Luxury Van Repair

    May I simply just say what a comfort to find someone that actually understands what they are discussing on the internet. You definitely know how to bring an issue to light and make it important. More and more people need to read this and understand this side of the story. I can't believe you aren't more popular because you definitely possess the gift.

    http://forum.kinoafisha.info/cc.php?url=https://pumastorejava.co.id/smartblog/11_PUMA-RS-X-Retro-Futurism-Blend-style-and-sp.html

    June 1, 2021 at 11:09 | Report abuse | Reply
  2. national interstate rv insurance reviews

    http://www.1919gogo.com/afindex.php?page=https://forum.fabricadeplante.ro/showthread.php?tid=10241&pid=36686

    June 1, 2021 at 12:13 | Report abuse | Reply
  3. paint a horse trailer

    Having read this I believed it was rather enlightening. I appreciate you taking the time and energy to put this content together. I once again find myself spending way too much time both reading and commenting. But so what, it was still worth it!

    /

    June 1, 2021 at 12:17 | Report abuse | Reply
  4. Mertie Dutta

    http://dol.deliver.ifeng.com/c?z=ifeng&la=0&si=2&cg=1&c=1&ci=2&or=7549&l=28704&bg=28703&b=37275&u=https://griffinm93a4.isblog.net/rumored-buzz-on-repair-shop-17948563

    June 1, 2021 at 15:40 | Report abuse | Reply
  5. Johnson Robar

    https://rspcb.safety.fhwa.dot.gov/pageRedirect.aspx?RedirectedURL=https://jeffreyw25a3.mpeblog.com/24460354/a-simple-key-for-smoke-shop-unveiled

    June 1, 2021 at 15:44 | Report abuse | Reply
  6. Kena Pierce

    https://go.onelink.me/v1xd?pid=Patch&c=Mobile20Footer&af_web_dp=http://sergios15e6.blogproducer.com/5674061/the-5-second-trick-for-internet-marketing-consultant

    June 2, 2021 at 06:29 | Report abuse | Reply
  7. Sprinter Van Paint Shop Near Me

    /

    June 2, 2021 at 07:56 | Report abuse | Reply
  8. rv cabinets and furniture

    http://www.treasury.gov/cgi-bin/redirect.cgi/?http://www.ingenieurleistungenreiter.com/index.php?option=com_phocaguestbook&view=phocaguestbook&id=1&Itemid=4&limitstart=85100

    June 2, 2021 at 10:01 | Report abuse | Reply
  9. Graham Letourneau

    https://reddit.app.link/?channel=mweb_branch&feature=xpromo&campaign=xpromo&$og_redirect=https://charliex25b4.bcbloggers.com/4334944/exactly-what-is-existence-coaching-and-why-lifetime-coaching-might-be-for-you-personally

    June 2, 2021 at 11:14 | Report abuse | Reply
  10. orange county car upholstery

    I was able to find good information from your blog posts.

    https://dmca.com/Protection/Status.aspx?ID=edc817fd-d796-4c84-abb8-d1cb5b2e3719&refurl=https://www.luxurybusinessmanagement.blogdun.com/2470629/helping-the-others-realize-the-advantages-of-rv-repair-shop

    June 2, 2021 at 11:42 | Report abuse | Reply
  11. Mercedes Cargo Van Repair Shop

    http://www.p-hero.com/hsee/rank.cgi?mode=link&id=88&url=https://npcnewstv.com/2019-npc-natural-eastern-usa-mens-physique-classic-physique-overall-winner-daniel-kolbrich/

    June 2, 2021 at 13:56 | Report abuse | Reply
  12. rv repair santa fe

    You ought to take part in a contest for one of the highest quality blogs online. I most certainly will recommend this website!

    https://za.zalo.me/v3/verifyv2/pc?token=OcNsmjfpL0XY2F3BtHzNRs4A-hhQ5q5sPXtbk3O&continue=9zest.com/guide/tremor-parkinsons-disease/

    June 2, 2021 at 15:45 | Report abuse | Reply
  13. Nissan Luxury Van Repair

    http://happylife.com/__media__/js/netsoltrademark.php?d=raisingcolorado.com/2011/05/sharps.html/comment-page-231

    June 2, 2021 at 15:48 | Report abuse | Reply
  14. Shemika Porta

    http://dol.deliver.ifeng.com/c?z=ifeng&la=0&si=2&cg=1&c=1&ci=2&or=7549&l=28704&bg=28703&b=37275&u=https://beckettj94g7.canariblogs.com/the-smart-trick-of-van-repair-shop-that-no-one-is-discussing-16245025

    June 2, 2021 at 20:32 | Report abuse | Reply
  15. Royal Leusink

    http://dol.deliver.ifeng.com/c?z=ifeng&la=0&si=2&cg=1&c=1&ci=2&or=7549&l=28704&bg=28703&b=37275&u=https://reidp93v1.mybloglicious.com/23718925/considerations-to-know-about-rv-body-repair

    June 3, 2021 at 00:30 | Report abuse | Reply
  16. Desmond Masucci

    I need to to thank you for this very good read!! I certainly loved every little bit of it. I have you book-marked to check out new things you post…

    https://rspcb.safety.fhwa.dot.gov/pageRedirect.aspx?RedirectedURL=https://emiliog58j7.free-blogz.com/47484003/the-5-second-trick-for-rv-body-shop

    June 3, 2021 at 01:18 | Report abuse | Reply
  17. binance app review

    These are genuinely wonderful ideas in on the topic of blogging.
    You have touched some good things here. Any way keep up wrinting.

    June 3, 2021 at 02:07 | Report abuse | Reply
  18. RV Driver Seats Near Me

    You've made some good points there. I checked on the net to learn more about the issue and found most individuals will go along with your views on this site.

    http://www.offroadamerica.com/__media__/js/netsoltrademark.php?d=ocrvmotorsports.us/

    June 3, 2021 at 04:00 | Report abuse | Reply
  19. Social Media Marketing Agencies

    http://blog.tieonline.com/feedtie/feed2js.php?src=https://www.seopostfalls.com/ &num=3&au=y&date=y&utf=y&html=y

    June 3, 2021 at 05:05 | Report abuse | Reply
  20. Digital Marketing Agency

    Hi there! This article couldn’t be written any better! Going through this article reminds me of my previous roommate! He always kept preaching about this. I'll send this information to him. Pretty sure he's going to have a very good read. Thank you for sharing!

    http://www.shelterisland.com/__media__/js/netsoltrademark.php?d=nearmyspot.com/

    June 3, 2021 at 05:09 | Report abuse | Reply
  21. Google Marketing Companies

    I seriously love your site.. Excellent colors & theme. Did you develop this site yourself? Please reply back as Iím trying to create my very own website and would like to know where you got this from or what the theme is named. Thank you!

    http://ace-ace.co.jp/cgi-bin/ys4/rank.cgi?mode=link&id=26651&url=https://meticulousjess.com

    June 3, 2021 at 13:24 | Report abuse | Reply
  22. Sprinter Fuel Filler Pipe Repair

    Aw, this was an incredibly good post. Taking the time and actual effort to produce a good article… but what can I say… I put things off a whole lot and don't manage to get nearly anything done.

    http://www.iate89.ru/info.php?a%5B%5D=http://bestkamery.pl/produkty/kamery-sportowe/kamera-sportowa-bc-sj4000/+(<a+href=http://commercialvanrepairshop.com

    June 3, 2021 at 14:36 | Report abuse | Reply
  23. Keystone Sprinter Tank Repair Leaking

    https://privatelink.de/?http://youtube.com/watch?v=BIx3f6Ksv6c

    June 3, 2021 at 16:42 | Report abuse | Reply
  24. trailer repair near me now

    https://icewarp.cz/ru/downloads/redir/?link=http://youtube.com/watch?v=w9cLLsF5HEg

    June 3, 2021 at 16:50 | Report abuse | Reply
  25. cabinet repair service near me

    Oh my goodness! Awesome article dude! Thank you so much, However I am going through issues with your RSS. I donít understand the reason why I can't subscribe to it. Is there anyone else getting similar RSS issues? Anyone that knows the answer will you kindly respond? Thanks!!

    http://ams.ceu.edu/optimal/optimal.php?url=http://www.youtube.com/watch?v=ceJGVRPSV7U

    June 3, 2021 at 16:57 | Report abuse | Reply
  26. camera repair orange county ca

    Pretty! This was an extremely wonderful article. Thanks for providing this info.

    http://nagano.visit-town.com/functions/external_link?http://youtube.com/watch?v=JWuVf_sMn5A/

    June 3, 2021 at 16:59 | Report abuse | Reply
  27. 2004 Mercedes Sprinter Engine Block Repair

    http://www.google.com.pg/url?q=http://youtube.com/watch?v=TX4MKltw7-k/

    June 3, 2021 at 17:00 | Report abuse | Reply
  28. rv body shop near me

    http://citrix.iamgold.com/__media__/js/netsoltrademark.php?d=youtube.com/watch?v=p6wZCWW6ciA

    June 4, 2021 at 00:27 | Report abuse | Reply
  29. Sprinter Van Repair

    Right here is the right web site for anybody who wants to find out about this topic. You know a whole lot its almost hard to argue with you (not that I personally will need toÖHaHa). You definitely put a fresh spin on a topic which has been written about for a long time. Wonderful stuff, just excellent!

    http://ottollc.com/__media__/js/netsoltrademark.php?d=www.orangecountyrvrepair.com

    June 4, 2021 at 02:03 | Report abuse | Reply
  30. Digital Marketing Experts

    http://squawkbox.com/__media__/js/netsoltrademark.php?d=www.lifeboosterpack.com/

    June 4, 2021 at 02:10 | Report abuse | Reply
  31. togel online

    Saktibet Bandar Judi Online 24jam Transfer Pulsa Terdepan dengan taruhan terpopuler.
    Tinggal memanfaatkan 1 ID saja untuk segala betting seperti:
    • Slot Mesin
    • Live Casino
    • Tarujam Sbobet
    • Fish Hunting
    • Poker Online
    • Game Togel Online
    Menerima Transfer bank Lokal 24jam tanpa Henti.

    Deposit bisa memakai emoney seperti Dana, Ovo, Gopay dan Link Aja.
    Juga menerima pulsa Telkomsel dan juga XL.
    Untuk perihal lebih lanjut kalian dipersilahkan mengklik penghubung yang tertulis di bawah ini:
    Whatsapp : +62 8199-459-7290
    Line : cs.saktibet
    Link Main : saktibet.link
    Link Main : https://www.saktibet.link/

    June 4, 2021 at 02:16 | Report abuse | Reply
  32. Sprinter Truck Repair

    Hello there, There's no doubt that your site may be having web browser compatibility issues. Whenever I take a look at your web site in Safari, it looks fine however, if opening in Internet Explorer, it has some overlapping issues. I merely wanted to give you a quick heads up! Other than that, fantastic blog!

    http://redirects.tradedoubler.com/utm/td_redirect.php?td_keep_old_utm_value=1&url=http://ocrv.vip/rv-repair-shop-pomona-california

    June 4, 2021 at 02:17 | Report abuse | Reply
  33. beaches near me

    Oh my goodness! Amazing article dude! Thanks, However I am experiencing difficulties with your RSS. I donít understand the reason why I cannot join it. Is there anybody else getting similar RSS problems? Anyone who knows the solution will you kindly respond? Thanx!!

    http://leadertoday.org/topframe2014.php?goto=https://bulknearme.com

    June 4, 2021 at 02:18 | Report abuse | Reply
  34. Dodge Sprinter Service Near Me

    Everything is very open with a really clear clarification of the issues. It was really informative. Your website is useful. Thank you for sharing!

    http://tk-80.com/__media__/js/netsoltrademark.php?d=fleetvehiclerepairshop.com/

    June 4, 2021 at 02:18 | Report abuse | Reply
  35. Service A Mercedes Sprinter

    I could not refrain from commenting. Exceptionally well written!

    http://altoonamirror.net/__media__/js/netsoltrademark.php?d=sprintervanrepair.com/

    June 4, 2021 at 04:30 | Report abuse | Reply
  36. Dodge Sprinter Service Centers

    Very nice post. I certainly love this site. Thanks!

    http://www.foreseeresults.ws/__media__/js/netsoltrademark.php?d=ocrv.online

    June 4, 2021 at 09:52 | Report abuse | Reply
  37. rv mechanic near me

    https://sso.aoa.org/Authenticate.aspx?Return=https://ocrv.life/rv-repair-shop-norco-california

    June 4, 2021 at 13:31 | Report abuse | Reply
  38. bed bath and beyond near me

    http://uglyidaho.com/__media__/js/netsoltrademark.php?d=bulknearme.com/

    June 4, 2021 at 13:35 | Report abuse | Reply
  39. Sprinter Van Side Repair Price

    Way cool! Some very valid points! I appreciate you penning this article and the rest of the website is extremely good.

    http://www.salarycoach.com/__media__/js/netsoltrademark.php?d=fleetrepairshops.com/

    June 4, 2021 at 13:54 | Report abuse | Reply
  40. Sprinter Van Repair Shops Near Me

    Greetings! Very useful advice in this particular article! It's the little changes which will make the largest changes. Many thanks for sharing!

    http://whatsyoursign.com/__media__/js/netsoltrademark.php?d=www.sprintervanrepair.com/

    June 4, 2021 at 14:56 | Report abuse | Reply
  41. oranges for sale near me

    Everything is very open with a really clear clarification of the issues. It was truly informative. Your site is useful. Many thanks for sharing!

    http://jpg.heuveltransport.com/__media__/js/netsoltrademark.php?d=ocrvshop.com/

    June 4, 2021 at 17:41 | Report abuse | Reply
  42. Video Marketing Company

    http://gatedpeople.net/__media__/js/netsoltrademark.php?d=meticulousjessmarketing.com

    June 5, 2021 at 01:24 | Report abuse | Reply
  43. Freightliner Sprinter Repair Near Me

    http://dncdirector.com/__media__/js/netsoltrademark.php?d=ocrvart.com/

    June 5, 2021 at 01:39 | Report abuse | Reply
  44. Rust Repair Sprinter

    Great article. I'm going through many of these issues as well..

    https://www.mydoterra.com/Application/index.cfm?EnrollerID=458046&Theme=DefaultTheme&ReturnURL=ocrv.today/rv-repair-shop-bell-gardens-california

    June 5, 2021 at 02:12 | Report abuse | Reply
  45. pet stores near me

    Good information. Lucky me I ran across your site by accident (stumbleupon). I have book-marked it for later!

    http://fausel.net/__media__/js/netsoltrademark.php?d=www.bestlocalnearme.com

    June 5, 2021 at 02:18 | Report abuse | Reply
  46. 2003 Sprinter Ac Repair

    I'm very happy to find this page. I want to to thank you for your time just for this fantastic read!! I definitely really liked every part of it and i also have you book marked to see new information in your site.

    http://aurora.network/redirect?url=http://sprintervanrepairnearme.com/

    June 5, 2021 at 02:23 | Report abuse | Reply
  47. http://compositecenter.org/

    Hi, i believe that i saw you visited my blog thus i got here to go back the desire?.I am trying to in finding issues to enhance
    my site!I suppose its good enough to make use of some of
    your concepts!!

    June 5, 2021 at 02:26 | Report abuse | Reply
  48. 32955 Sprinter Repair

    I was pretty pleased to discover this great site. I want to to thank you for ones time due to this wonderful read!! I definitely savored every little bit of it and I have you bookmarked to see new things in your website.

    http://www.expertoptimization.com/__media__/js/netsoltrademark.php?d=fleetvehiclerepairshop.com/

    June 5, 2021 at 03:38 | Report abuse | Reply
  49. Release Clip Repair On Mercedes Sprinter Seat

    http://www.feldfire.net/__media__/js/netsoltrademark.php?d=sprintervanrepair.com

    June 5, 2021 at 20:03 | Report abuse | Reply
  50. Dodge Sprinter Repair Near Me

    After I originally left a comment I seem to have clicked on the -Notify me when new comments are added- checkbox and now each time a comment is added I recieve four emails with the exact same comment. Perhaps there is a means you are able to remove me from that service? Thanks a lot!

    https://www.ontariocourts.ca/search-canlii/scj/newdecisions-en.php?link=http://ocrv.world/rv-repair-shop-palm-desert-california

    June 5, 2021 at 20:46 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.