home
RSS
September 13th, 2010
12:02 AM ET

Study: Men with low initial PSA levels less likely to develop prostate cancer

Men with low PSA levels from a baseline blood test were less likely to develop prostate cancer compared to men whose baseline PSA levels were high, according to a new study.

The simple test may be a strong predictor of who will benefit from future screening and treatment for prostate cancer, according to the study published Monday in the journal Cancer.

More than 85,000 men, ages 55 to 74, with no previous prostate cancer history were the subjects of the study. The authors found that in order to save one life, they needed to investigate almost  25,000 men with low PSA levels but only 133 men with high ones. Similarly, they needed to treat 724 men who had low PSA levels to save one life but only 60 men whose levels were higher.

PSA, or prostate-specific antigen, is a protein found in prostate cancer tissue. When that tissue breaks down, the protein seeps into the bloodstream. The heavier the presence of PSA in the blood, the more likely prostate cancer will be dangerous and require some type of treatment, said Dr. Otis Brawley, Chief Medical Officer at American Cancer Society and a contributor to CNNHealth.com.

But aren't all cancers bad, even if a man's PSA level is low?

"There are a large number of prostate cancers that don't need to be treated because they're not a health threat to the man who has them," explained Brawley.  That makes guidelines for screenings more difficult to set.

The American Cancer Society encourages men to work with their doctors to learn about the test's benefits and risks before making an informed personal decision around age 50.   Research has not yet proven that the potential benefits of testing outweigh the harms of testing and treatment, explains the organization.

The American Urology Association recommends baseline screening for men at age 40 with future screenings determined in conjunction with the patient's doctor.

"This can't be done in a vacuum," said Dr. J. Brantley Thrasher, spokesman for the American Urology Association and the William L. Balk Chair of the Department of Urology at the University of Kansas. "We need to let [patients] know this is an imperfect marker, but we're getting data that may help us in the future."

It's difficult to accept the idea that you could have prostate cancer that doesn't need to be treated and could be left alone with no harm, while other men have aggressive and deadly prostate cancers.  Brawley, who chooses not to be screened, thinks this is why most men get PSA tests regularly, despite the many risks associated treatment.

"By choosing to get screened, there is a guaranteed increase in diagnosis... but there is only a potential decrease in death," said Brawley.

Some of the risks of treatment include impotence, incontinence and bowel injury.

Still, Thrasher says the importance of the PSA blood test should not be diminished. He tells his patients to get regular screenings every other year or every three years after their initial test.

"I believe knowledge is power to some extent," said Thrasher. "It's risks versus benefits... and each decision point is a fork in the road where [me and patients] have to have a discussion."


soundoff (708 Responses)
  1. RV Repair Centers Near Me

    https://aritc.yru.ac.th/redirect/78?url=https://www.ocrvshop.com

    June 23, 2021 at 01:50 | Report abuse | Reply
  2. Digital Marketing Near Me

    This page certainly has all the info I needed concerning this subject and didnít know who to ask.

    http://mfpwa.com/__media__/js/netsoltrademark.php?d=consciousgrowthmarketing.com

    June 23, 2021 at 02:00 | Report abuse | Reply
  3. RV Repair Places Near Me

    http://sadiemadison.tc/__media__/js/netsoltrademark.php?d=ocrvcenter.com

    June 23, 2021 at 06:45 | Report abuse | Reply
  4. RV Mobile Repair Service Near Me

    Hello! I simply would like to give you a big thumbs up for your excellent info you've got here on this post. I will be returning to your website for more soon.

    https://www.soyyooestacaido.com/www.watsonbuys.com

    June 23, 2021 at 11:18 | Report abuse | Reply
  5. RV Body Repair Shops Near Me

    This website was... how do you say it? Relevant!! Finally I have found something that helped me. Thank you!

    https://www.springsguide.com/util/urlclick.aspx?obj=DIListing&id=17470&url=https://watsonbuys.com/sell-my-house-fast/

    June 23, 2021 at 12:19 | Report abuse | Reply
  6. RV Repair Center Near Me

    http://www.bytecheck.com/results?resource=ocrv.org/

    June 23, 2021 at 14:02 | Report abuse | Reply
  7. Internet Marketing Specialist

    Everything is very open with a precise explanation of the issues. It was definitely informative. Your website is very helpful. Thanks for sharing!

    http://1-888-low-bail.com/__media__/js/netsoltrademark.php?d=boosterpackforlife.com

    June 23, 2021 at 14:34 | Report abuse | Reply
  8. wawa near me

    Everything is very open with a really clear explanation of the issues. It was definitely informative. Your website is very helpful. Many thanks for sharing!

    http://www.ahaonline.org/__media__/js/netsoltrademark.php?d=www.bjsnearme.com

    June 23, 2021 at 17:46 | Report abuse | Reply
  9. RV Chassis Repair Near Me

    I like it when people come together and share views. Great blog, stick with it!

    https://www.viagginrete-it.it/urlesterno.asp?url=http://orangecountyrvrepair.com/

    June 23, 2021 at 18:37 | Report abuse | Reply
  10. SEO Marketing Company

    http://barclay-foundation.org/__media__/js/netsoltrademark.php?d=getmoneytraveling.com/

    June 23, 2021 at 19:29 | Report abuse | Reply
  11. Local Marketing Experts

    This is a good tip particularly to those new to the blogosphere. Brief but very accurate infoÖ Appreciate your sharing this one. A must read post!

    http://www.leasethatplane.com/__media__/js/netsoltrademark.php?d=codymarketing.com

    June 23, 2021 at 20:40 | Report abuse | Reply
  12. RV Repair And Service Near Me

    http://youngertube.com/cgi-bin/atx/out.cgi?id=487&tag=twitter&trade=https://ocrv.tv

    June 23, 2021 at 22:26 | Report abuse | Reply
  13. RV Repair Places Near Me

    Hi there! I could have sworn Iíve visited this blog before but after looking at some of the articles I realized itís new to me. Anyhow, Iím certainly delighted I found it and Iíll be bookmarking it and checking back regularly!

    http://hinewest.com/__media__/js/netsoltrademark.php?d=ocrvparts.com

    June 24, 2021 at 05:52 | Report abuse | Reply
  14. RV Plumbing Repair Near Me

    I blog frequently and I genuinely thank you for your information. The article has really peaked my interest. I'm going to book mark your website and keep checking for new information about once a week. I opted in for your Feed as well.

    https://2013ebookcase.gogofinder.com.tw/index/link.php?id=8&link=https://oc-rv.com/

    June 24, 2021 at 06:04 | Report abuse | Reply
  15. Content Marketing Consultants

    After exploring a few of the articles on your web page, I seriously appreciate your way of writing a blog. I book-marked it to my bookmark webpage list and will be checking back soon. Take a look at my web site as well and let me know how you feel.

    http://delmarforum.org/__media__/js/netsoltrademark.php?d=juicycalls.com/

    June 24, 2021 at 07:03 | Report abuse | Reply
  16. Video Marketing Specialist

    http://www.clean-dry.biz/__media__/js/netsoltrademark.php?d=consciousgrowthmarketing.com

    June 24, 2021 at 07:05 | Report abuse | Reply
  17. red robin near me

    Iím amazed, I have to admit. Seldom do I encounter a blog thatís equally educative and entertaining, and let me tell you, you have hit the nail on the head. The problem is an issue that not enough men and women are speaking intelligently about. I am very happy that I found this during my hunt for something regarding this.

    http://younglist.net/cgi-bin/out.cgi?ses=U4T2sDe36l&id=206&url=https://bjsnearme.com/

    June 24, 2021 at 08:43 | Report abuse | Reply
  18. Video Marketing Consultant

    Greetings! Very useful advice in this particular article! It is the little changes which will make the most important changes. Many thanks for sharing!

    http://soft.lissi.ru/redir.php?_link=http://lifeboosterpack.com

    June 24, 2021 at 09:30 | Report abuse | Reply
  19. Social Media Marketing Businesses

    http://ce-cs.net/__media__/js/netsoltrademark.php?d=hiddenapples.com/

    June 24, 2021 at 09:48 | Report abuse | Reply
  20. Video Marketing Companies Near Me

    https://www.koni-store.ru/bitrix/redirect.php?event1=OME&event2=&event3=&goto=https://rankemailads.com/

    June 24, 2021 at 13:03 | Report abuse | Reply
  21. motor home repair parts

    Spot on with this write-up, I actually believe this website needs a lot more attention. Iíll probably be returning to read more, thanks for the advice!

    https://www.vfao.com/login.aspx?returnurl=https://ocrvcenter.com

    June 24, 2021 at 13:13 | Report abuse | Reply
  22. Camper Repair Places Near Me

    This is a really good tip particularly to those fresh to the blogosphere. Short but very precise informationÖ Many thanks for sharing this one. A must read post!

    https://www.bigcosmic.com/board/s/board.cgi?id=tetsujin&mode=damy&moveurl=www.ocrvcenter.com

    June 24, 2021 at 16:30 | Report abuse | Reply
  23. RV Satellite Repair Near Me

    https://2style.net/out.php?id=rinoda&url=ocrvcenter.com/

    June 24, 2021 at 20:15 | Report abuse | Reply
  24. Sprinter Repair Shops Near Me

    This is the right website for everyone who wants to understand this topic. You understand a whole lot its almost tough to argue with you (not that I really would want toÖHaHa). You definitely put a brand new spin on a subject that's been discussed for ages. Excellent stuff, just wonderful!

    https://www.rvlife.com/click?dealer_ad=&dadid=29&url=http://ocrvcenter.com/

    June 24, 2021 at 22:53 | Report abuse | Reply
  25. RV Repair Mission Viejo

    http://www.kunstbuchanzeiger.de/link.php?url=https://www.ocrvcenter.com/

    June 25, 2021 at 02:50 | Report abuse | Reply
  26. Camper Repairs Near Me

    http://www.bshare.cn/share?url=http://ocrvcenter.com/

    June 25, 2021 at 03:01 | Report abuse | Reply
  27. RV Roof Repair Service Near Me

    This site really has all of the information and facts I wanted concerning this subject and didnít know who to ask.

    https://studeo.icp.fr/url?https://ocrvcenter.com/

    June 25, 2021 at 08:42 | Report abuse | Reply
  28. RV Water Repair Man Near Me

    /

    June 25, 2021 at 12:14 | Report abuse | Reply
  29. Camper Repair Near Me

    https://lcu.hlcommission.org/lcu/pages/auth/forgotPassword.aspx?Returnurl=https://www.soulkids.org

    June 25, 2021 at 14:19 | Report abuse | Reply
  30. Camper Repairs Near Me

    https://netshop.misty.ne.jp/fashion/05/out.cgi?id=uenon&url=https://www.www.charlie7l01d.blogaritma.com

    June 25, 2021 at 17:24 | Report abuse | Reply
  31. RV Brake Repair Near Me

    http://www.osbar.org/secured/plf/remote_logout.asp?returnurl=https://www.jysk.co.id/en/smartblog/39_HOW-TO-CHOOSE-HAND-SANITIZER-TO-PREVENT-COVID.html

    June 25, 2021 at 17:25 | Report abuse | Reply
  32. RV Repair Nearby

    Everything is very open with a precise explanation of the issues. It was definitely informative. Your website is useful. Many thanks for sharing!

    https://responsivedesignchecker.com/checker.php?url=beau8a6y4.sharebyblog.com/&width=1400&height=700

    June 25, 2021 at 17:32 | Report abuse | Reply
  33. RV Roof Repair Service Near Me

    This is a topic that is near to my heart... Thank you! Where are your contact details though?

    /

    June 25, 2021 at 21:10 | Report abuse | Reply
  34. Norberto Blakely

    https://netshop.misty.ne.jp/beauty/01/out.cgi?id=vertrich&url=https://wildwestforkliftschool.com

    June 25, 2021 at 22:03 | Report abuse | Reply
  35. RV Air Conditioner Repair Near Me

    https://www.dmsg.de/externerlink.php?url=http://donovan4c7q2.onzeblog.com/3500052/the-basic-principles-of-rv-service-near-me

    June 25, 2021 at 22:03 | Report abuse | Reply
  36. RV Repair Orange County

    http://www.pcpitstop.com/offsite.asp?https://mamasmusicstore.it

    June 26, 2021 at 02:33 | Report abuse | Reply
  37. RV Repair

    https://jamesattorney.agilecrm.com/click?u=https://angelo0l6u9.azzablog.com/

    June 26, 2021 at 03:07 | Report abuse | Reply
  38. Sprinter Repair Shop Near Me

    Spot on with this write-up, I seriously think this site needs a lot more attention. Iíll probably be back again to read through more, thanks for the info!

    https://foaf-visualizer.gnu.org.ua/?url=https://www.easylinkdirectory.com/

    June 26, 2021 at 10:29 | Report abuse | Reply
  39. Errol Beiter

    https://blogranking.fc2.com/out.php?id=414788&url=https://www.allamericanstatewidesecurity.com

    June 26, 2021 at 11:51 | Report abuse | Reply
  40. Joeann Eberlein

    I was able to find good advice from your content.

    http://sc.devb.gov.hk/TuniS/www.ocrv.today/

    June 26, 2021 at 14:13 | Report abuse | Reply
  41. RV Glass Repair Near Me

    Hi there! This post couldnít be written much better! Looking at this article reminds me of my previous roommate! He always kept talking about this. I'll forward this post to him. Pretty sure he'll have a great read. Thanks for sharing!

    /

    June 26, 2021 at 15:07 | Report abuse | Reply
  42. Oswaldo Sieczkowski

    I could not refrain from commenting. Very well written!

    https://polo-v1.feathr.co/v1/analytics/crumb?flvr=email_link_click&rdr=http://masteringthemanwithin.com

    June 26, 2021 at 15:16 | Report abuse | Reply
  43. Long Mazell

    After looking into a handful of the articles on your web page, I really appreciate your technique of writing a blog. I saved it to my bookmark site list and will be checking back in the near future. Take a look at my website as well and let me know how you feel.

    https://www.rya.org.uk/coursestraining/professional/pages/redir.axd?url=http://ocrv.art/

    June 26, 2021 at 15:25 | Report abuse | Reply
  44. RV Repair California

    I was able to find good advice from your blog articles.

    https://sherlock.scribblelive.com/r?u=http://acinstallationserviceinna86065.thechapblog.com/

    June 26, 2021 at 15:48 | Report abuse | Reply
  45. Books On Leadership

    Howdy, I believe your web site could be having web browser compatibility problems. Whenever I look at your site in Safari, it looks fine however when opening in I.E., it's got some overlapping issues. I just wanted to provide you with a quick heads up! Besides that, fantastic blog!

    http://www.dogfriendly.com/servlet/refer?from=pageFL&dest=https://backboneleaders.com

    June 26, 2021 at 16:23 | Report abuse | Reply
  46. National Student Leadership Conference

    You need to take part in a contest for one of the greatest blogs on the net. I am going to highly recommend this blog!

    http://go.isclix.com/deep_link/4694673464837045969?url=http://backboneleaders.com

    June 26, 2021 at 18:26 | Report abuse | Reply
  47. What Is Your Leadership Style

    https://pt-br.paltalk.com/client/webapp/client/External.wmt?url=https://backboneleaders.com

    June 26, 2021 at 19:29 | Report abuse | Reply
  48. spittin chiclets podcast

    This website certainly has all of the information and facts I wanted about this subject and didnít know who to ask.

    https://ssp.send.microad.jp/cc?ep=3WkB-sR7-kgCUB3oC4dc3s608eSsloN9K9NHq6iY9RsN0FgxwNmpck0T4k-9LLI9yuidcEtEYotIEUzjREa-S5R4v2nHvcF0QtXiQsDdubYMYrJ_XftQVRNkmURGNS6aGMDFcsiCQl_lNKo507iRUEbVxoJ8HW2yDEKqX54dvXTI&r=https://www.backbonehunters.com

    June 26, 2021 at 20:25 | Report abuse | Reply
  49. sofa king podcast

    http://yumi.rgr.jp/puku-board/kboard.cgi?mode=res_html&owner=proscar&url=www.backbonehunters.com

    June 26, 2021 at 20:53 | Report abuse | Reply
  50. Leadership Activities

    Everything is very open with a really clear description of the challenges. It was really informative. Your site is useful. Thanks for sharing!

    http://timemapper.okfnlabs.org/view?url=https://backboneleaders.com/

    June 27, 2021 at 03:17 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.