home
RSS
May 4th, 2010
11:05 PM ET

Scientists use pig embryo to create stem cells

By Miriam Falco
CNN Medical Managing Editor

Scientists appear to have broken another barrier in stem cell research by creating a better research model to study human illnesses – a pig – actually 34 pigs.

It’s an important advance for research because pigs are much more like humans than other lab animals are.

The scientists did not clone the pigs – instead they adapted a procedure used in mice and human stem cell research and were able to grow a specific kind of cell, induced pluripotent stem cells, or IPS cells.

Pluripotent stem cells have the ability to turn into any cell in the body. IPS cells were first developed about five years ago by Shinya Yamanaka, who used four genes to coax a regular mouse cell into acting like an embryo. Creating stem cells with this method is less controversial than harvesting them from an embryo, which destroys the fertilized egg in the process.

According to Dr. Steve Stice, director of the University of Georgia Regenerative Bioscience Center, his team took a bone marrow cell from a pig and injected six new genes, which caused it turn into an embryo-like cell.  Pluripotent stem cells were harvested from this embryo-like cell and injected in another pig embryo. 

The first piglets carrying these new stem cells were born September 3, 2009. 

So far human embryonic stem cell research has not actually found its way into the human body.  Most of the research is still in mice.  But mice aren't the best animal models to get more accurate data on how a treatment may affect a person.  For example, mice hearts beat four times faster than a human heart and mice don't get atherosclerosis (clogged arteries) – but pigs do.  That's why pigs are much better animal models says Stice. "Physiologically, pigs are much closer to a human," he says.

The researchers also found that unlike mouse embryonic stem cells, which can turn into cancer cells, none of the pigs developed any signs of tumors.

But it has been very difficult to harvest embryonic pluripotent stem cells from pigs. Stice credits his research assistant Franklin West with finding a way to make the existing IPS technology work in pigs.  

Now researchers hope to find many different applications for these new pig stem cells and the pigs they can produce.  They are already working with scientists at Emory University to develop insulin-producing pancreatic islet cells, which might be transplanted into people with diabetes.

Stice thinks this new method can also be used to genetically engineer healthier livestock for other tissue transplants and food consumption. He suggests these stem cells may someday be used to make "artificial bacon," which would eliminate the need to slaughter pigs.

The research will be published in the online journal "Stem Cell and Development."

Editor's Note: Medical news is a popular but sensitive subject rooted in science. We receive many comments on this blog each day; not all are posted. Our hope is that much will be learned from the sharing of useful information and personal experiences based on the medical and health topics of the blog. We encourage you to focus your comments on those medical and health topics and we appreciate your input. Thank you for your participation.


soundoff (105 Responses)
  1. FgvdZisse

    pharmacy prices the drug store specialty pharmacy

    January 11, 2021 at 23:57 | Report abuse | Reply
  2. Vince Gear

    There is evidently a bundle to know about this. I assume you made certain nice points in features also.

    http://yourmatrixcashmachine.com

    January 12, 2021 at 01:25 | Report abuse | Reply
  3. KhthMile

    texas state board of pharmacy canada online pharmacy north drug store

    January 13, 2021 at 06:26 | Report abuse | Reply
  4. JvcxCrulk

    buy sildenafil viagra overnight united states viagra buy generic viagra viagra viagra natural china viagras 100mg viagra online in australia cheap what drugstore can i buy viagra in hong kong viagra in los angeles canadian viagra buy via paypal online viagra austalia viagra with depoxatine overnight shipping levitra vs cialis vs viagra buy viagra new york viagra vs cialis which is better

    January 14, 2021 at 20:44 | Report abuse | Reply
  5. FgnhZisse

    united states viagra online viagra no prescription minute clinic viagra cheap viagra viagra without prescription where to buy viagra in sydney viagra .com generic viagra canada cheep viagra viagra vs cialis reviews viagra dealers in malaysia viagra in india viagra australia paypal how to take viagra buy generic viagra on line

    January 16, 2021 at 02:46 | Report abuse | Reply
  6. KlioMile

    buy viagra with echeck generic viagra buy online cheap viagra online australia quick ship viagra viagra brand viagra 100mg viagra buy canada viagra without prescription femal viagra what doctor prescribes viagra suppliers of generic viagra best place to buy online viagra buy viagra cheap viagra online canada buy viagra in canadГЎ

    January 18, 2021 at 08:22 | Report abuse | Reply
  7. AqbvEncox

    viagra in montreal cialis viagra 100mg viagra for sale http://acialaarx.com/ – viagra gold bestellen ’

    January 19, 2021 at 05:26 | Report abuse | Reply
  8. JvcbxCrulk

    cialis in vegas get online cialis without prescription overnight brand cialis with prescription http://phrcialiled.com/ – best prices for cialis ’

    January 19, 2021 at 20:29 | Report abuse | Reply
  9. LcxEncox

    kamagra vs viagra viagra vor sale uk viagra without a rx http://genqpviag.com/ – amazon viagra ’

    January 20, 2021 at 10:19 | Report abuse | Reply
  10. NlbxZisse

    cialis at a discount generic cialis india cialis soft tabs, united states origin http://cialijomen.com/ – cialis for sale ’

    January 20, 2021 at 16:07 | Report abuse | Reply
  11. FbdhZisse

    bootleg cialis cialis 20 mg best price mastercard cialis http://21cialismen.com/ – where to buy cialis ’

    January 21, 2021 at 03:15 | Report abuse | Reply
  12. JbdcEncox

    austalia online viagra viagra for sale pay pal viagra on sale http://llviabest.com/ – viagra coupon code ’

    January 21, 2021 at 08:55 | Report abuse | Reply
  13. KbctMile

    buy generic cialis australia cialis pay pal free samples cialis http://mycialedst.com/ – cialis paypal accepted australia ’

    January 22, 2021 at 22:28 | Report abuse | Reply
  14. AhmdEncox

    viagra/cialis cialis ordering viagra cialis trial pack http://cialmenshoprx.com/ – order online cialis with dapoxetine ’

    January 24, 2021 at 00:16 | Report abuse | Reply
  15. JnhCrulk

    cialis without perscriptions cialis on line paypal payment free cialis no prescription http://loncialis.com/ – cialis most trusted ’

    January 24, 2021 at 10:08 | Report abuse | Reply
  16. NmilZisse

    viagra 300mg brand viagra cheap 50 viagra on line\' http://xz-pharmacyonline.com/en/career-opportunities.html – viagra under 50 ’

    January 25, 2021 at 11:04 | Report abuse | Reply
  17. FbgZisse

    buy viagra online flavor viagra cialis viagra sales https://canadianpharmacy-usx.com/organic.htm – least expensive viagra ’

    January 25, 2021 at 22:56 | Report abuse | Reply
  18. FmfvEncox

    trial pack cialis viagra levitro cialis 36 hour online cialis for daily use http://sjcialis.com/ – canadian pharmacy viagra & cialis ’

    January 27, 2021 at 05:18 | Report abuse | Reply
  19. KbbtMile

    buy cialis online medical information online how to get cialis 800mg https://xz-pharmacyonline.com – best 10 online canadian pharmacies ’

    January 27, 2021 at 07:15 | Report abuse | Reply
  20. Ciara Nass

    Thanks for the sensible critique. Me and my neighbor were just preparing to do some research on this. We got a grab a book from our local library but I think I learned more from this post. I am very glad to see such fantastic info being shared freely out there.

    https://www.electricpercolatorcoffeepot.com/10-top-coffee-bloggers/

    January 28, 2021 at 22:01 | Report abuse | Reply
  21. AhmdEncox

    cialis 10mg Prevacid cialis canadian pharmacy https://impotencecdny.com/ – pharmacy drug store ’

    January 29, 2021 at 06:58 | Report abuse | Reply
  22. JnscCrulk

    buy viagra online professional viagra viagra online purchase http://erectilejyzd.com/index.php?called=terms – brand viagra 20 mg ’

    January 29, 2021 at 16:39 | Report abuse | Reply
  23. NgscZisse

    viagra soft gel go deal now where to get viagra over the counter http://canadianpharmacy-yy.com/Fitness/how-to-get-a-six-pack.html – how to get viagra without a prescription ’

    January 30, 2021 at 17:21 | Report abuse | Reply
  24. FhnhZisse

    Imdur walmart online pharmacy online medicine order discount https://canadianpharmacy-yy.com/ – apollo pharmacy online ’

    January 31, 2021 at 05:00 | Report abuse | Reply
  25. Lee Virelli

    This is a very interesting article. Please, share more like this!

    https://yt1s.com

    February 1, 2021 at 09:51 | Report abuse | Reply
  26. FmnfEncox

    how to buy cialis us cialis 800mg black cialis without a pescripton https://impotencecdny.com/info/history.php – cialis without perscription ’

    February 1, 2021 at 12:26 | Report abuse | Reply
  27. KbbgMile

    dapoxetine viagra canadadrugs to buy viagra generic http://erectilejyzd.com/ – Danazol ’

    February 1, 2021 at 13:17 | Report abuse | Reply
  28. NncsZisse

    prescription drugs prices side effects of viagra super force viagra and sports performance

    February 3, 2021 at 10:12 | Report abuse | Reply
  29. JbbvEncox

    canada pharmacies without script pharmacy drugstore online online pharmacies

    February 3, 2021 at 19:06 | Report abuse | Reply
  30. FvfcZisse

    online discount pharmacy viagra mit paypal viagra gel karmagara australia

    February 4, 2021 at 15:41 | Report abuse | Reply
  31. Kuikseelt

    free viagra pills what are the over the counter viagra viagra natural china

    February 4, 2021 at 17:48 | Report abuse | Reply
  32. JbnbCrulk

    no prescription online pharmacy online medicine to buy viagra pharmacy 100mg

    February 5, 2021 at 04:21 | Report abuse | Reply
  33. zortilonrel

    It's a pity you don't have a donate button! I'd without a doubt donate to this fantastic blog! I guess for now i'll settle for book-marking and adding your RSS feed to my Google account. I look forward to new updates and will share this blog with my Facebook group. Chat soon!

    http://www.zortilonrel.com/

    February 7, 2021 at 05:49 | Report abuse | Reply
  34. AhkdEncox

    online pharmacies uk price pro pharmacy canada dapoxetine

    February 7, 2021 at 16:22 | Report abuse | Reply
  35. LbsxEncox

    prescription prices comparison most reliable viagra walmart pharmacy price check

    February 7, 2021 at 16:59 | Report abuse | Reply
  36. zortilonrel

    It's a pity you don't have a donate button! I'd without a doubt donate to this brilliant blog! I suppose for now i'll settle for bookmarking and adding your RSS feed to my Google account. I look forward to brand new updates and will share this website with my Facebook group. Chat soon!

    http://www.zortilonrel.com/

    February 7, 2021 at 18:14 | Report abuse | Reply
  37. KbcxMile

    most reliable canadian pharmacies canadian pharmacy viagra brand mental illness

    February 8, 2021 at 00:47 | Report abuse | Reply
  38. FqhhEncox

    publix pharmacy online ordering discount pharmaceuticals cheap drugs

    February 8, 2021 at 16:34 | Report abuse | Reply
  39. Europa-Road gépszállítás

    I do not even know how I ended up here, but I thought this post was great. I don't know who you are but certainly you're going to a famous blogger if you are not already 😉 Cheers!

    https://europa-road.eu/hu/gepszallitas.php

    February 9, 2021 at 03:15 | Report abuse | Reply
  40. FÓKUSZBAN 2002 Bt

    It is really a great and helpful piece of information. I’m glad that you shared this helpful information with us. Please keep us up to date like this. Thank you for sharing.

    http://www.fokuszpalyazat.hu/rolunk

    February 9, 2021 at 03:46 | Report abuse | Reply
  41. https://europa-road.eu/hu/traktor-szallitas.php

    Thanks for any other informative website. The place else may just I am getting that kind of info written in such an ideal method? I've a project that I'm simply now operating on, and I've been at the look out for such info.

    https://europa-road.eu/hu/traktor-szallitas.php

    February 9, 2021 at 04:56 | Report abuse | Reply
  42. Learn More

    Great – I should certainly pronounce, impressed with your website. I had no trouble navigating through all the tabs and related info ended up being truly simple to do to access. I recently found what I hoped for before you know it at all. Reasonably unusual. Is likely to appreciate it for those who add forums or something, website theme . a tones way for your customer to communicate. Nice task..

    http://www.dumpawaste.co.uk

    February 9, 2021 at 08:17 | Report abuse | Reply
  43. JbbnEncox

    which one is better viagra cialis levitra 1-800-cialis meglio il viagra o il cialis

    February 10, 2021 at 17:36 | Report abuse | Reply
  44. NbnhZisse

    viagra 100mg cost http://vigedon.com/ viagra sales online

    February 11, 2021 at 09:54 | Report abuse | Reply
  45. Kbbfseelt

    buy viagra canada viagra online bestellen org ganeric viagra

    February 11, 2021 at 20:36 | Report abuse | Reply
  46. JbnvCrulk

    cash advance fletcher instant cash advance rockingham canadian online payday loans fast

    February 12, 2021 at 05:33 | Report abuse | Reply
  47. FbsgZisse

    generic cialis http://llecialisjaw.com/ cialis best price

    February 12, 2021 at 13:55 | Report abuse | Reply
  48. LabxEncox

    ancillary guys liquid cialis sahan gökbakar cialis cialis originale miglior prezzo

    February 14, 2021 at 07:35 | Report abuse | Reply
  49. KvaxMile

    best payday loans in pa cash advance best buy card ace cash advance indianapolis

    February 15, 2021 at 09:16 | Report abuse | Reply
  50. AhbzEncox

    payday loans in gresham oregon states where online payday loans are illegal moneyline loan reviews

    February 16, 2021 at 00:19 | Report abuse | Reply
1 2 3

Post a comment


 

CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

Advertisement
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.