March 15th, 2010
05:00 PM ET

Hip fractures more deadly to men

By Saundra Young
CNN Medical Senior Producer

Editor's note: In a previous version of this post, the form of zoledronic acid that reduced death rates by 28 percent over a three-year period was inaccurately identified. The correct form of the drug is Reclast

Hip fractures. They're breaks in the upper part of the femur or thigh bone, most often caused by a fall. People 65 and older are most vulnerable, and according to the American Academy of Orthopedic Surgeons, women have two to three times as many fractures as men. But a new study in the Annals of Internal Medicine says men are at greater risk of dying because of it.

[cnn-photo-caption image=
http://i2.cdn.turner.com/cnn/2010/images/03/15/story.hip.men.gi.jpg caption="Hip fractures are more deadly for men."]

Researchers looked at 39 studies involving nearly 600,000 women and 155,000 men over the age of 50, with hip fracture. They found that while older women are nearly six times more likely to die after a fracture than a woman without a break, older men are about eight times as likely to die in the first three months after their injury.

"Hip fractures are associated with a substantially increased risk of death for both men and women which lasts for at least 10 years after the fracture," said Dr. Cathleen Colon-Emeric, one of the study authors at Duke University Medical Center in Durham, North Carolina. "This highlights the importance of interventions which reduce operative complications and the physical decline that frequently results from a hip fracture."

Researchers are not quite sure why the risk of death increases. But Colon-Emeric says hip fracture is a major blow to your body. "People with hip fractures tend to be more frail. Many have underlying medical problems that put them at higher risk of death, like stroke, Parkinson's disease and dementia."

Earlier studies found that after a hip fracture men are more likely than women to die of infectious conditions such as sepsis and pneumonia.

Only 25 percent of these fractures occur in men. Dr. Jay Magaziner, chairman of the Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland in Baltimore, and a study co-author, says if you project forward to 2050, there will be as many hip fractures in men as there are currently in women today. "We know that men who fracture their hip are generally a bit sicker. They have more medical conditions at the time of their fracture than women. One of the reasons that we believe that is the case, is the natural process of aging post-menopausally in women."

Magaziner says the combination of falling and weak bones will create a hip fracture. He says women lose a little bit of bone each year after menopause, but men don't lose bone naturally. In fact, in order for men to lose enough bone to have a break when they fall, they generally have to have an underlying medical condition. "Women who fracture don't have these other medical problems, so that may be one of the reasons that we're seeing a higher mortality rate in men than women."

Dr. Sandra Fryhofer, an Atlanta, Georgia, internist and past president of the American College of Physicians, says the study is a wake-up call that men can get osteoporosis too. "It stresses the importance of prevention, making sure people are getting calcium, vitamin D and weight-bearing exercises like walking. Anything that puts weight on the bones, because that stimulates new bone formation."

Because men have not received a lot of attention on hip fracture and osteoporosis, Magaziner is working on new research to try to better understand the disparities. "If we can understand the differences in the way men and women respond to having a hip fracture then we can tailor our treatments to these differences and the way people recover," he said. "We want to individualize the way we treat patients."

Colon-Emeric says one treatment has proved to reduce mortality after fracture, an osteoporosis drug zoledronic acid or Reclast. It's made by pharmaceutical giant Novartis and new data show it reduced death rates by 28 percent over a three-year period. It's given once a year intravenously in a doctor’s office and it reduced the chance of additional fractures by 20 percent in a two-year period. Promising, because statistics show one in five will re-fracture their hip.

Editor's Note: Medical news is a popular but sensitive subject rooted in science. We receive many comments on this blog each day; not all are posted. Our hope is that much will be learned from the sharing of useful information and personal experiences based on the medical and health topics of the blog. We encourage you to focus your comments on those medical and health topics and we appreciate your input. Thank you for your participation.

soundoff (595 Responses)
  1. olesapora

    металлические люки от производителя или купить металлические люки


    April 28, 2021 at 16:17 | Report abuse | Reply
  2. LrbsEncox

    levitra side effects long term https://uslevitraanna.com/ levitra without a doctor prescription

    April 29, 2021 at 10:39 | Report abuse | Reply
  3. RfvbZisse

    order cialis http://cileve.com/ – cialis free samples cialis generic 20 mg

    April 29, 2021 at 11:49 | Report abuse | Reply
  4. erectile dysfunction drug

    erectile destroyer https://canadaerectiledysfunctionpills.com/ do erectile dysfunction pills really work

    April 29, 2021 at 13:32 | Report abuse | Reply
  5. Established loan consolidation company

    this is very informative and intersting for those who are interested in blogging field.


    April 29, 2021 at 14:37 | Report abuse | Reply
  6. window washing denver CO

    Commenting on a blog is an art. Good comments create relations. You're doing great work. Keep it up.


    April 29, 2021 at 15:42 | Report abuse | Reply
  7. https://www.songmanhits.com

    Best view i have ever seen !


    April 29, 2021 at 17:51 | Report abuse | Reply
  8. ed meds

    men with erectile dysfunction https://canadaerectiledysfunctionpills.com/ best erectile pills

    April 30, 2021 at 19:37 | Report abuse | Reply
  9. GvdbCrulk

    tadalafil 60 mg reviews http://boxtadafil.com/ tadalafil 20mg price in india

    April 30, 2021 at 22:16 | Report abuse | Reply
  10. LhdvZisse

    cialis on line purchase https://asciled.com/ cialis shipping

    May 1, 2021 at 03:39 | Report abuse | Reply
  11. FbsfEncox

    canadian pharmacy uk delivery http://uspharmus.com/ – order prescriptions online without doctor canadian pharmacy 365

    May 1, 2021 at 03:59 | Report abuse | Reply
  12. buy viagra from canada?

    canada cheap viagra https://canadaviagrastore.com/ is it legal to bring viagra back to canada from mexico

    May 1, 2021 at 16:59 | Report abuse | Reply
  13. GvdbCrulk

    is there a generic tadalafil http://boxtadafil.com/ – tadalafil dosage instructions tadalafil or viagra

    May 1, 2021 at 17:54 | Report abuse | Reply
  14. RfvbZisse

    voucher cialis index https://cileve.com/ cialis debit card

    May 2, 2021 at 06:38 | Report abuse | Reply
  15. canadian pharmacy 5 mg daily cialis

    cialis at canadian pharmacy https://canadacialisstore.com/ canadian pharmacy no perscription generic cialis

    May 2, 2021 at 12:59 | Report abuse | Reply
  16. LhdvZisse

    levitra vs cialis http://asciled.com/ cialis voucher

    May 2, 2021 at 20:41 | Report abuse | Reply
  17. AbdgEncox

    Buspar http://canadianeve21.com/ panacea pharmacy

    May 3, 2021 at 01:36 | Report abuse | Reply
  18. Matthew Schneider

    I was able to find good information from your content.


    May 3, 2021 at 04:49 | Report abuse | Reply
  19. LrbsEncox

    price of levitra at walgreens http://uslevitraanna.com/ glaxo levitra

    May 3, 2021 at 05:29 | Report abuse | Reply
  20. LebnEncox

    online pharmacy viagra https://xlnpharmacy.com/ prescription drug assistance

    May 3, 2021 at 06:45 | Report abuse | Reply
  21. dapoxetine

    priligy without a doctor prescription dapoxetine 1mg

    May 3, 2021 at 12:08 | Report abuse | Reply
  22. 카지노사이트



    May 3, 2021 at 22:27 | Report abuse | Reply
  23. 카지노사이트



    May 3, 2021 at 22:27 | Report abuse | Reply
  24. FmrfEncox

    cialis los angeles http://cialisee.com/ cialis online

    May 4, 2021 at 02:53 | Report abuse | Reply
  25. BbshMile

    female viagra http://loxviagra.com/ cost of viagra at cvs

    May 4, 2021 at 02:57 | Report abuse | Reply
  26. RebfZisse

    cialis 80 mg https://rcialisgl.com/ – brand cialis in canada cialis for sale brand

    May 4, 2021 at 12:20 | Report abuse | Reply
  27. LbsoZisse

    cialis black uk http://ucialisdas.com/ – cialis on lone brand cialis us

    May 5, 2021 at 08:09 | Report abuse | Reply
  28. Airgun megastore best bb guns for kids

    Commenting on a blog is an art. Good comments create relations. You're doing great work. Keep it up.


    May 5, 2021 at 16:28 | Report abuse | Reply
  29. Karate Gambrills MD

    I really like this post


    May 5, 2021 at 17:05 | Report abuse | Reply
  30. Cupids Health


    There is a candle in your heart, ready to be kindled.

    There is a void in your soul, ready to be filled.

    You feel it, dont you?


    Be the first to know important health alerts.

    Award winning Health Alert Website.

    May 5, 2021 at 18:49 | Report abuse | Reply
  31. BbshMile

    viagra wiki https://loxviagra.com/ – viagra vs cialis hardness viagra for men for sale

    May 5, 2021 at 19:42 | Report abuse | Reply
  32. dapoxetine

    priligy dapoxetine priligy pills for sale

    May 5, 2021 at 21:30 | Report abuse | Reply
  33. AnooEncox

    time for viagra to work http://llviagra.com/ – viagra price list india buying viagra in sweden

    May 6, 2021 at 06:13 | Report abuse | Reply
  34. RebfZisse

    daily use cialis cost https://rcialisgl.com/ cialis free samples

    May 6, 2021 at 07:57 | Report abuse | Reply
  35. hydroxychloroquine plaquenil

    chloroquina https://chloroquineorigin.com/ chloroquinw

    May 6, 2021 at 18:15 | Report abuse | Reply
  36. LebnEncox

    all in one pharmacy overseas online pharmacy online pharmacy australia

    May 6, 2021 at 18:31 | Report abuse | Reply
  37. LbsoZisse

    generic cialis without prescription https://ucialisdas.com/ how many milligrams of cialis can you take in a day ?

    May 6, 2021 at 22:13 | Report abuse | Reply
  38. JebgEncox

    Micardis Trimox generic viagra online

    May 7, 2021 at 14:21 | Report abuse | Reply
  39. AnooEncox

    how to buy viagra in hong kong https://llviagra.com/ sex offenders to use viagra

    May 7, 2021 at 17:09 | Report abuse | Reply
  40. AlexPeedy

    Монтаж напольных покрытий
    Монтаж напольного плинтуса!..

    May 7, 2021 at 21:06 | Report abuse | Reply
  41. JebgEncox

    cheap rx Levitra impotence

    May 8, 2021 at 09:25 | Report abuse | Reply
  42. hidroxicloroquina

    chrloroquine https://chloroquineorigin.com/ where to get chloroquine

    May 8, 2021 at 21:26 | Report abuse | Reply
  43. FmrfEncox

    cialis https://cialisee.com/ – cialis us pharmacy cialis doesn\'t work

    May 9, 2021 at 03:13 | Report abuse | Reply
  44. GtnbCrulk

    is viagra a controlled substance http://jokviagra.com/ gabapentin and viagra

    May 9, 2021 at 14:22 | Report abuse | Reply
  45. GtnbCrulk

    how to use viagra for best results https://jokviagra.com/ when to take viagra

    May 9, 2021 at 23:38 | Report abuse | Reply
  46. LebnEncox

    aarp approved canadian online pharmacies Motrin on line pharmacy

    May 10, 2021 at 05:02 | Report abuse | Reply
  47. FmrfEncox

    cialis promise program https://cialisee.com/ cialis 10 mg

    May 11, 2021 at 05:27 | Report abuse | Reply
  48. BbshMile

    natural viagra foods http://loxviagra.com/ viagra precio

    May 11, 2021 at 08:25 | Report abuse | Reply
  49. RebfZisse

    cialis black 800mg http://rcialisgl.com/ cialis purchase

    May 11, 2021 at 09:56 | Report abuse | Reply
  50. Jackeline Petroff


    May 12, 2021 at 03:58 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12

Leave a Reply to LebnEncox


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.