March 12th, 2010
05:12 PM ET

FDA issues new warning for Plavix

By Saundra Young
CNN Medical Senior Producer

A new boxed warning has been added to the anti-blood clotting drug Plavix by the Food and Drug Administration, who says the medication doesn't work well in people who have difficulty metabolizing the drug.

Plavix is used by patients with heart disease to help decrease risk of heart attack, stroke and death. It works on platelets–special blood cells that help blood clot to stop bleeding–by preventing blood clots from forming.

Plavix needs to be activated by the liver enzyme, CYP2C19. Patients that have reduced liver enzyme function can't activate the drug making it less effective for them. They're called "poor metabolizers" and this puts them at greater risk of heart attack, stroke and death.

"We want to highlight this warning to make sure health care professionals use the best information possible to treat their patients," said Mary Ross Southworth, a clinical analyst in the Division of Cardiovascular and Renal Products in the FDA's Center for Drug Evaluation and Research.

The Agency says there are tests available to evaluate CYP2C19 and determine if you are a "poor metabolizer." They say patients should talk to their doctors to determine if they should stop taking the drug.

Last November the FDA issued a warning about using Plavix in conjunction with over the counter stomach acid reducer Prilosec and Prilosec OTC when new data found that taking the two together reducedPlavix's anti-clotting effect by about half. .

Plavix is available only by prescription. It's made by Bristol-Myer Squibb and Sanofi Aventis, who issued the following statement "The revisions to the prescribing information for Plavix reflect the companies' ongoing research in collaboration with the FDA, which better defines the patient population that may be affected by a genetic variation in CYP2C19 and alternate treatment strategies."

Editor's Note: Medical news is a popular but sensitive subject rooted in science. We receive many comments on this blog each day; not all are posted. Our hope is that much will be learned from the sharing of useful information and personal experiences based on the medical and health topics of the blog. We encourage you to focus your comments on those medical and health topics and we appreciate your input. Thank you for your participation.

soundoff (1,596 Responses)
  1. WillieHus

    Ежедневные порнуха на телефон бесплатно чтобы народа! Качественная и красивая Порнуха HD. Порно ролики в охеренном качестве 720p и 1080p домашняя женская мастурбация записи видео коситься позволительно https://xepok.online/categories/%D0%A0%D0%B5%D1%82%D1%80%D0%BE/ даром 24 часа 365 дней!

    April 13, 2021 at 19:31 | Report abuse | Reply
  2. Cortez Nelder

    Great write-up, I am normal visitor of one’s website, maintain up the nice operate, and It is going to be a regular visitor for a lengthy time.


    April 13, 2021 at 19:47 | Report abuse | Reply
  3. RafaelKnorn

    Хотите обманывать бал порнуха крупным планом с удовольствием? Порно видео ебля с женой помогут вам в этом, не теряйте времени. Заходите в категорию «порно инцест», чтоб полюбоваться чистый сын трахнул мать: девственной, с заметный дыркой, с пирсингом alias с татуировкой. Посетив категорию «домашнее порно», сможете понимать прекрасную женскую грудь разного размера и формы, которая просто не оставит вас в покое. Надоело смотреть https://sextut.top/categories/%D0%94%D0%B5%D0%B4+%D0%95%D0%B1%D0%B5%D1%82+%D0%92%D0%BD%D1%83%D1%87%D0%BA%D1%83/ порнуху в видосах тут много порно инцест мама трахается с сыном порно фото сообразно категориям.

    April 13, 2021 at 20:29 | Report abuse | Reply
  4. alprostadil dosage

    how much alprostadil vials https://alprostadildrugs.com/ muse injection

    April 14, 2021 at 02:03 | Report abuse | Reply
  5. HelenGal

    Israel Haifa Bat Galim

    חיפה בת גלים

    April 14, 2021 at 10:49 | Report abuse | Reply
  6. Billaek

    Date Asian a woman

    published in Dating Tips, online dating site tagged Asian lady, Autumn dating, , fall in love this fall, IDto be found ateAsia of 8:48 am made by Idateasia

    It's starting to be cooler, Can you feel it? certainly, Autumn just received here. And the completed of summer. I know most of you are gonna miss our summer days and parties! within the, Autumn is also a great season. It just amuses you diversely.

    Personally autumn is definitely the season in a year; weather is really comfortable, Neither too hot nor freezing. the outdoors becomes quiet, And you look right out of the window seeing a leaf dancing in the air and then fall down on the shoulder of a young man, But he doesn notice that and keeps talking to the girl next to him and she's giggling. What amazing sight!

    Autumn is a nostalgic season because it can easily wake up the deepest emotions inside our heart. It reminds us of the past and the joyful memories in those days, And it makes us happy and feel a little sad in the same time frame. when you're single, much like me, It might also remind you of love and romance. Your heart feels empty and wants something to meet it. the urge for love is never so strong. Here are some tips which you amuse your lovely Asian lady:

    Write her an enchanting love poem. Women love sweet afro introductions reviews words and they always want to be the heroine in your goal, Your story additionally your poem. It's only to be very long, Just as well as sweet. in the final analysis of the letter, Attach a recent photo of yourself experiencing and enjoying the autumn day.

    Sing a love song for my child. Pick a love song and record it by computer or other audio device, weeks done, Make a love call to the lady and let her hear it with phone. it would be a surprise!

    Fly over to fulfill her. If you been dating for a few months and get ready for the next move, Your unexpected show up must become amongst the best memories in her life. Then you can walk outside with your beautiful Asian lady, You're telling you, She's giggling and the leaf's dancing in an airplane.

    fall madly in love this fall. sure, this FREE, in other words, You may have a trial of its featured services like browsing photos of gorgeous Asian singles and a brief live chat with pretty Asian girls without costing a penny, simply to it your call, To decide whether they should call be the member of this Asian dating site or not.

    in my opinion, This free trial is open to anyone who wants to find a Southeast Asian girlfriend or a exotic Asian bride. So if you seeking an interracial alliance with some hot Thai girl, careful Vietnamese lady or sexy Philippines woman, Don miss an opportunity! just get in!

    And exactly what can you get from the FREE trial? 1) 20 minutes of FREE online chat with the greatest Asian singles; 2) 5 FREE e-mails or EMF mail correspondences; 3) Browse snap shots of thousands of prettyAsian ladies; 4) Get a FREE view show the particular hotties.

    So do you want to get the FREE TRAIL now? Click this link to create an account and finish the sign up process with your basic personal information, then you get the OFFER!

    the fall of 5, 2013Lady, So call us by phone Me, or maybe?

    Posted in online dating services tagged Asian dating, , IDateAsia company, young lady call me, online dating sites at 8:31 am a Idateasia

    Carly Rae Jepsen gets popular combined with her song Call Me Maybe. many families love this song. And I also crazy about it. I guess it tells our deep wants to be chased and to be loved! on the whole, Girls will give out their phone number when they meet someone handsome or attracted to them, Hoping you day he will call her and ask her out for a date. But should you follow guys? Should he wait to get the telephone number? How about he supplying the contact way and letting girls make the first call? could it be possible?

    understand, everyone, You really can make her call you first. clearly, Our staffs always watch your requests and are making every effort to improve our dating services to meet your needs during the online dating process, So just lately iDateAsia has launched a new featured service LADY CALL ME!

    Call Service is the perfect way to hear her voice! Use any mobile phone or land line to get connected and talk to your girl directly or in a 3 way call with professional translation assist with help overcome language and cultural barriers! There are 3 solutions to make a Love Call on iDateAsia, immediate Calls, appointed Calls and Lady Call Me.

    April 14, 2021 at 11:11 | Report abuse | Reply
  7. Alexinedy

    Movers Los Angeles

    April 14, 2021 at 11:47 | Report abuse | Reply
  8. cialis viagra combination canadian pharmacy

    canadian viagra cialis https://canadacialisstore.com/ cialis canadian discounts

    April 14, 2021 at 17:03 | Report abuse | Reply
  9. is it illegal to by viagra from canada

    organic viagra in canada https://canadaviagrastore.com/ generic viagra shipping from canada

    April 14, 2021 at 20:09 | Report abuse | Reply
  10. Anthonywoove

    Рассматривать порно поза видео домашняя порно фильмы https://jaebu.online/categories/%D0%9C%D0%B8%D0%BD%D0%B5%D1%82/ для взрослых со смыслом и русским переводом онлайн, порно анал ганг банг домашний

    April 14, 2021 at 21:54 | Report abuse | Reply
  11. azithromycin zithromax

    is zithromax an antibiotic https://zithromaxes.com/ chlamydia powder medication

    April 14, 2021 at 23:51 | Report abuse | Reply
  12. Larrymow

    Trusted Online Casino Malaysia http://gm231.com/poker/#Poker – Click here>>>

    April 15, 2021 at 09:04 | Report abuse | Reply
  13. Richarddig


    April 15, 2021 at 10:22 | Report abuse | Reply
  14. tadalis sx

    generic tadalafil united states https://elitadalafill.com/ generic tadalafil

    April 15, 2021 at 13:23 | Report abuse | Reply
  15. vardenafil cvs

    teva pharms vardenafil https://vegavardenafil.com/ why vardenafil dosage over 65

    April 15, 2021 at 20:40 | Report abuse | Reply
  16. lok

    Всем привет!
    Жизненно серьезный и важный вопрос!?
    Уважаемые и дорогие мужчины, помогите!
    Кто разбирается и понимает в строительстве фундамента для бани, дома, дачи, гаража есть такие?
    Было бы отлично и здорово, если бы вы занимались и имели бы опыт в строительстве фундаментов, есть такие?
    В интернете много говорят и пишут о строительстве фундамента за 50% или за полцены.
    Мне интересно это уловка или правда?
    Нашла в интернете сайт Школы частных прорабов Prorab2.ru, они утверждают, что можно строить качественные и дешевые фундаменты для дома, дачи, бани, гаража и т.д.
    Это правда или нет, действительно можно строить фундаменты за полцены или за 1/2, соблюдая все строительные нормы и не нарушая технологического процесса?
    Взгляд на вещи у меня конечно женский, а не мужской, мне что-то мало в это верится, в общем, я сомневаюсь и колеблюсь.
    Сайт у них конечно пояснительный и хороший, с множеством подробных и разъясняющих статей с схематическими рисунками и таблицами, например:
    Школа Частных Прорабов Prorab2ru
    После прочтения нескольких статей и ознакомления с сайтом начинаешь верить в правдоподобность и реальность этого утверждения.
    Действительно начинаешь верить в строительство дешевых и качественных фундаментов под дачу, дом, баню, гараж и т.д. за полцены или 1/2.
    Еще есть важный и хороший момент, на сайте есть раздел посвященный психологии в строительстве и ремонте, в нем рассказывается обо всех строительных и ремонтных процессах, как бы изнутри.
    Есть моменты и тонкости, о которых вообще ни кто не рассказывает и не пишет, например:
    Безопасность строительства и ремонта: Как определить брак
    Профессионалы, специалисты и практики в строительстве фундаментов, можно ли строить дешевые и качественные фундаменты за полцены или за 50% от цены фундамента, или нельзя?
    Вот адрес Школы частных прорабов Prorab2.ru, обучающей и осуществляющей строительство фундаментов за полцены или за 50% от цены фундамента https://prorab2.ru/ .
    До новых встреч!

    April 16, 2021 at 03:39 | Report abuse | Reply
  17. Knvpllfrine

    дубна гравий купить
    Tegs: дубна купить щебень https://dubna-pesok.ru

    купить почвогрунт дубна кимры талдом
    купить чернозем в дубне
    купить чернозем в дубне московской области

    April 16, 2021 at 03:53 | Report abuse | Reply
  18. pffhmbxAnnuada


    April 16, 2021 at 11:13 | Report abuse | Reply
  19. UnelteshopSquig

    Aparat de stropit

    Drujbe puternice

    Invertor Industrial

    Masina de tuns iarba


    April 16, 2021 at 12:41 | Report abuse | Reply
  20. trimix v alprostadil

    cheap alprostadil https://alprostadildrugs.com/ alprostadil pellet

    April 16, 2021 at 13:29 | Report abuse | Reply
  21. LeoldGap


    April 16, 2021 at 14:58 | Report abuse | Reply
  22. Kennethlom

    http://www.pure-season.club/ – Индивидуальные туры в Женеву цены

    April 16, 2021 at 15:38 | Report abuse | Reply
  23. how to buy teva sub for viagra in canada

    buy viagra from canada? https://canadaviagrastore.com/ best canada viagra pills online

    April 16, 2021 at 18:51 | Report abuse | Reply
  24. tadalafil max dose

    tadalafil online https://elitadalafill.com/ tadalafil dosage

    April 16, 2021 at 23:22 | Report abuse | Reply
  25. ArthurTum

    Смотрите отборное порнуха с негром с толстой жопой онлайн https://365sexp.xyz/categories/%D0%9C%D0%B0%D0%BB%D0%B5%D0%BD%D1%8C%D0%BA%D0%B8%D0%B5+%D0%A1%D0%B8%D1%81%D1%8C%D0%BA%D0%B8/ бескорыстно в хорошем качестве. Порнуха HD. Порно 365 дней в году 24 часа в сутки! Ебля и картинный секс русские реальные домашние зрелыми женщинами порно сообразно категориям. Свободный порно сайт для гурманов!

    April 16, 2021 at 23:31 | Report abuse | Reply
  26. JeffreyGax

    Бесплатное https://eropron.top/categories/%D0%93%D1%80%D1%83%D0%B4%D1%8C+%D0%9A%D1%80%D0%B0%D1%81%D0%B8%D0%B2%D0%B0%D1%8F/ порно видео в хорошем качестве на страницах EROPRON.TOP) Один скачать порно с парнем отборное порево без рекламы и ежедневным обновлением

    русская зрелая сосет видео порно

    April 17, 2021 at 00:21 | Report abuse | Reply
  27. alprostadil penile suppository price

    cheap alprostadil https://alprostadildrugs.com/ alprostadil

    April 17, 2021 at 06:51 | Report abuse | Reply
  28. canada viagra

    viagra canada by mail https://canadaviagrastore.com/ viagra prices canada

    April 17, 2021 at 18:44 | Report abuse | Reply
  29. illegal sales of alprostadil

    alprostadil ingredients 745-65-3 https://alprostadildrugs.com/ alprostadil topical cream

    April 18, 2021 at 08:00 | Report abuse | Reply
  30. Rubinnug

    Порно видео на сайте [url=https://zaebal.online/]порно видео анал групповуха[/url] это ежедневное обновление секс роликов! [url=https://zaebal.online/categories/%D0%9C%D0%BE%D0%BB%D0%BE%D0%B4%D1%8B%D0%B5/]порно ебут толстую молодую русское[/url] Качай порнуху для телефон тож https://zaebal.online/categories/%D0%9C%D0%BE%D0%BB%D0%BE%D0%B4%D1%8B%D0%B5/ компьютер без ограничений.

    April 18, 2021 at 23:14 | Report abuse | Reply
  31. ThomasPer

    Иными словами, пакет услуг «Гражданство через инвестиции в недвижимость» — это выгодная и удобная долгосрочная партнерская программа, в результате которой наш клиент становится полноправным гражданином выбранной им стран
    [url=https://sothebys-realty.ru/]buy tadalafil pills[/url]

    April 19, 2021 at 00:19 | Report abuse | Reply
  32. Tungmjh

    assessment for sancerre1985

    the most significant here is how you feel, And to take into consideration any red flags with him. Your soon to be ex doesn't need to know what is taking place in your personal life, So I will suggest to avoid disclosing anything to him until divorce is way at the same time.Now in regards about meeting someone that make you feel right before getting divorce can totally happen. you don't have a 1 year rule : The critical is how you feel, And making sure you are not projecting any thing on him and your relationship which render it seems better than it is.I met my now wife several months after the divorce started with my ex. My ex wife was a cheater and was mentally sick but didn't need to get treated. I was not really looking to meet someone while the divorce was ongoing but clearly what we had was not a rebound (She was divorce herself and knew I was going to a divorce too). We both have been honest and direct from the beginning and I can tell that my relationship with her was way beyond what I had with my ex wife even after 15+ yearsI watch too for red flags since my ex had various mental illness and clearly there was none.Soon after the divorce was over I did propose to her on a trip, And last December we got wedded.So nutrients can happen when you expect it the least!I do imagine that when you find a great match, Fighting is not something which should really be happening.I was in a 15+ years relationship that ended in divorce: Lots of yelling mostly from my ex wife, And her turning violent from times to times.2 times later, After meeting the most amazing woman I could ever dream of (I just marital her) I can see that a great relationship doesn't involve fighting; There are disagreements but everything can be discussed and no yelling involved.we've been through a lot since we met and travel enough miles to go twice around earth (Sometimes going down the road over 24 hrs non stop) And even with the worry, Lack of sleep and discomfort that is included with such trips we just get along. Some trips wasn't pleasure trips (suffering with death in family) So we highly trained a lot.So I am now convinced that a good and solid affectionate doesn't involved fighting, And rather anything can be tackled.So trustworthy! I keep in after she filed for divorce, In a matters of [url=https://www.bestbrides.net/afrointroductions-review-2020-does-this-african-dating-site-work-for-you/]afrointroductions member login[/url] week many of the little things that I was bothered with became clearly visible of her laziness and how I was turning a blind eye on it.During our marriage she barely was cleaning after her mess: Socks left on the house, Dishes piled up in the sink with the pan/pot and anticipating that I will clean up the mess (I work full time and she barely was able to keep a job so she was often times at home or shopping)I was go glad I decided to move out and not have to deal with her mess anymore. And so glad we didn't have any kids because she will have made it difficult (She made it already very difficult so with kids it will have been extremely bad)Wishing the OP the most efficient.I can see the feeling after I moved out since I couldn't stand living under the same roof as my cheating ex wife (She was which one filed).I remember how happy I was when I got the key and a couple days later got the movers coming in and within 90 minutes got most of my stuff packed.It was a big downgrade moving from a home I own to a 1 bedroom/1 bath but not being in the same roof as her was a huge milestone. And truly this is too when my life grew to become back on track for the bestI had no idea that less than a month later after moving, My best friend suggested to sign up for some online dating service, Where soon after I met the most amazing woman I could dream of. go forward more 1.5 countless later, And I have moved out again to a home we are booking with my now fiance; The divorce has been finalized more than 6 months ago and my life went from a tiny amount of light in the length to a beautiful sunny and happy day.Moving to my apartment was the big turnaround so I still keep a warm happy feeling of getting my new personal space. Your life is just waiting to start again for the best.

    April 19, 2021 at 01:40 | Report abuse | Reply
  33. GalyaAnnuada


    April 19, 2021 at 11:14 | Report abuse | Reply
  34. MelvinDreft

    Hi all. af62194ee4c0d3225mdcb9222df83b w823

    April 19, 2021 at 11:40 | Report abuse | Reply
  35. skyreveryCrigh

    [url=https://skyrevery.ru/zakaz-chastnogo-samoleta/]Заказ частного самолета с экипажем, заказать частный самолет[/url] – подробнее на нашем сайте [url=https://skyrevery.ru]skyrevery.ru[/url]
    [url=https://skyrevery.ru/]Аренда частного самолета[/url] с экипажем в компании SkyRevery – это выбор тех, кто ценит свое время и живет по своему расписанию!
    Аренда частного самолета помогает экономить самый важный ресурс – время. Арендовав частный самолет, именно Вы решаете, когда и куда полетите. Для выполнения чартерных рейсов мы предлагаем частные самолеты иностранного производства, гарантирующие высокий уровень комфорта и безопасности полета. Внимательные бортпроводники и высокопрофессиональные пилоты сделают Ваш полет максимально приятным и удобным.
    Когда Вам нужна [url=https://skyrevery.ru/]аренда самолета[/url] срочно, мы можем организовать для Вас вылет по готовности от 3 часов с момента подтверждения.

    April 19, 2021 at 11:47 | Report abuse | Reply
  36. why vardenafil dosage over 65

    vardenafil cvs https://vegavardenafil.com/ vardenafil vs tadalafil

    April 19, 2021 at 12:43 | Report abuse | Reply
  37. canadian pharmacies ed pills

    canadian weight loss pills https://canadapillstorex.com/ canadian pharmacies ed pills

    April 19, 2021 at 17:12 | Report abuse | Reply
  38. ClaytonAronY



    April 19, 2021 at 19:39 | Report abuse | Reply
  39. portal sex randki

    What's up Dear, are you actually visiting this site on a regular basis, if so afterward
    you will absolutely get fastidious experience.

    April 19, 2021 at 21:23 | Report abuse | Reply
  40. CarrollBeado





    питомник спейс стар
    питомник мейн кунов лакшестар
    котята мейн кун спб недорого
    питомник мейн кунов спб
    купить мейн куна спб

    швеллер перфорированный 60х35 цена
    швеллер шп 60х35 перфорированный цена
    профиль zп 45х25
    астра электро
    цена швеллер перфорированный шп 60х35 у1

    April 20, 2021 at 01:40 | Report abuse | Reply
  41. Stephendob

    Созерцать порно зрелые хд чтобы взрослых со смыслом и русским переводом онлайн, домашнее секс видео без https://pizdato.vip/categories/%D0%A7%D1%83%D0%BB%D0%BA%D0%B8/ регистрации смотреть порно фото зрелых

    April 20, 2021 at 02:10 | Report abuse | Reply
  42. Qfshttj



    April 20, 2021 at 04:05 | Report abuse | Reply
  43. alprostadil penile injection

    alprostadil gel online https://alprostadildrugs.com/ buy muse alprostadil urethral suppository

    April 20, 2021 at 05:48 | Report abuse | Reply
  44. spravkimedikCrigh

    http://spravkimedik.ru – купить медицинскую справку 086у в красноярске – подробнее на нашем сайте http://spravkimedik.ru – spravkimedik.ru
    Личная http://spravkimedik.ru – медицинская книжка (http://spravkimedik.ru – санитарная книжка) – официальный документ строгой отчетности. В санитарной книжке отражаются все данные о результатах периодических осмотров, сдачи анализов и прививках, наличия инфекционных заболеваний, а также о прохождении курсов по гигиеническому воспитанию и аттестации.

    April 20, 2021 at 09:39 | Report abuse | Reply
  45. counterfeit canadian drugs cialis

    canadian pharmacy tadalafil viagara cialis https://canadacialisstore.com/ is it safe to order cialis from canadian pharmacy

    April 20, 2021 at 12:05 | Report abuse | Reply
  46. Petershale



    April 20, 2021 at 14:25 | Report abuse | Reply
  47. Claudiofreer

    Хотите посмотреть порно девушка кончает хорошо ? Тутто вам на PISIKA.TOP. Вы можете безвозмездно скачать порно кончающие зрелые дамы на лице с русскими красотками тож посмотреть https://pisika.top/categories/%D0%91%D1%80%D1%8E%D0%BD%D0%B5%D1%82%D0%BA%D0%B8/ онлайн даже с мобилы!

    April 20, 2021 at 15:15 | Report abuse | Reply
  48. ShawnSAL

    Крипто бот в телеграмм низкая комиссия для переводов Ethereum (ETH)

    Вывести крипто валюту

    April 20, 2021 at 17:42 | Report abuse | Reply
  49. tadalafil tablets

    tadalafil tablets https://elitadalafill.com/ tadalis sx

    April 20, 2021 at 18:51 | Report abuse | Reply
  50. canadian pills pharmacy

    canadian pills online https://canadapillstorex.com/ best canadian mail order pharmacies for diet pills

    April 20, 2021 at 19:14 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32

Post a comment


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.