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March 12th, 2010
05:12 PM ET
FDA issues new warning for PlavixBy Saundra Young A new boxed warning has been added to the anti-blood clotting drug Plavix by the Food and Drug Administration, who says the medication doesn't work well in people who have difficulty metabolizing the drug. Plavix is used by patients with heart disease to help decrease risk of heart attack, stroke and death. It works on platelets–special blood cells that help blood clot to stop bleeding–by preventing blood clots from forming. Plavix needs to be activated by the liver enzyme, CYP2C19. Patients that have reduced liver enzyme function can't activate the drug making it less effective for them. They're called "poor metabolizers" and this puts them at greater risk of heart attack, stroke and death. "We want to highlight this warning to make sure health care professionals use the best information possible to treat their patients," said Mary Ross Southworth, a clinical analyst in the Division of Cardiovascular and Renal Products in the FDA's Center for Drug Evaluation and Research. The Agency says there are tests available to evaluate CYP2C19 and determine if you are a "poor metabolizer." They say patients should talk to their doctors to determine if they should stop taking the drug. Last November the FDA issued a warning about using Plavix in conjunction with over the counter stomach acid reducer Prilosec and Prilosec OTC when new data found that taking the two together reducedPlavix's anti-clotting effect by about half. . Plavix is available only by prescription. It's made by Bristol-Myer Squibb and Sanofi Aventis, who issued the following statement "The revisions to the prescribing information for Plavix reflect the companies' ongoing research in collaboration with the FDA, which better defines the patient population that may be affected by a genetic variation in CYP2C19 and alternate treatment strategies." Editor's Note: Medical news is a popular but sensitive subject rooted in science. We receive many comments on this blog each day; not all are posted. Our hope is that much will be learned from the sharing of useful information and personal experiences based on the medical and health topics of the blog. We encourage you to focus your comments on those medical and health topics and we appreciate your input. Thank you for your participation. |
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I was so happy to get off of that drug. Taking it with aspirin on Dr's orders. When you get cut, you bleed and bleed and bleed. I would also get nose bleeds, which I never have had not taking that medication.
Hi, I'm just curious about what the possible symptom's or side effect's are with someone that is taking plavix and can not metabolize it proper.
The reason I'm asking is because my dad is on it and had been on it for almost 9 years now.
I'm on Plavix and aspirin as well, but 15 years post MI and open heart surgery plus two agioplasties and two stents, I'm alive and kicking and in the best health of my life. Sure I bleed a lot (I've ruined a lot of clothes from little scratchs and hangnails) but that's a small price to pay.
i had a heart attack ten years ago, since then I have been taking Plavix and aspirin, I do not like this medicine either, because of the excessive bruising and bleeding,even a minor cut can send me to a Doctor to control the bleeding. I have blood work done once a year to check liver function and cholesterol levels, would this test detect weather or not my liver was processing the drug? My tests have all been fine for liver function.
I think it is so scarry to beielve that moms and aunts and femal baby sitters are potentially dangerous that we do everything we can to shut out the information.Women have most of the access to children, and we like to think that they are all safe. It makes us feel better to do so, it is comfortable.But obviously, all women are not safe. And that is frightening. My daughter was harmed by a woman therapist. My father abused by a woman teacher for two years. We need to toughen up and face facts, that abuse is a human problem, not a male one.Trey
As a former Plavix user due to a stroke, my Veterans Administration doctor switched me to a drug named Aggrenox (aspirin/extended-release dipyridamole) which seems to do the same thing as Plavix, with less risk. M y health seems to be the same, and my life activity hasnt suffered. I think the world of the Veterans Administration health care for keeping me alive.
My Mother is 91 yrs old and has been on plavix for about four years. Her skin is very thin, the plavix makes her body looked bruised and very bad. Would you advise me to talk to the doctor about the drug which Jason Twomley wrote in his comment. She also bleeds when gets cuts. Her skin is so thin the doctor told us to be careful not to grab her arms because the skin could tear.
This new blackbox is not very useful clinically. I just don't see it ever happening where it becomes std of practice to order cyp isozyme evals for all patients.
Plavix is a fantastic drug...yes, you will tend to bleed a little bit longer, but hey, it beats being on coumadin and getting lab work done monthly(or more) or being on aggrenox and facing ridiculous headaches....and in the case of all these drugs, you face increased bleeding risk anyways.
I was recently told by a pharmacist that they would NOT put their spouse on Plavix (even though the spouse had a heart attack several years ago). Pharmacists know drugs. Doctor's often just prescribe and send you home. Is this a ambiguous drug with too many negative effects? Are their better options? Pharmacist recommends Vitamin E (at least 800IU). I had a TIA and can't get a clear perspective on this drug. Currently, Plavix lawsuits out there. It is now the second most prescribed drug on the market. Costly – no generic – big revenues for maker. Company did a little song and dance to renew patent on it. I would really like to know the truth about Plavix. I continue to ask doctors. Nothing but, "yes take it." I am allergic to aspirin.
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Great article.
wife had a stient and was put on plavix, which she was also taking prilosec. she said she felt 30yrs younger. within 2wks she got a rash on her lower body and not feeling as good as after the stient was put in. 4wks after stient she got a 3in blood clot at her stient and was in hospital 11wks, life support 3 times. doctor said it was due to the prilosec counteracting the plavix. she is waiting for a heart transplant now. I have read that the drug company that makes plavix knew about the problem. too late for my wife. the FDA has finally expressed a concern.
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οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½. οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½ 60 % οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½. οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½.
οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½. οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½, οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½, οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½. οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½. οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½, οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½ οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½οΏ½.
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http://a9m.ru/p/7197/ – Π Π΅ΠΊΠ»Π°ΠΌΠΎΠ΄Π°ΡΠ΅Π»Ρ
ΠΠΏΠ»Π°ΡΠΈΠ²Π°ΡΡΡΡ ΡΠΎΠ»ΡΠΊΠΎ ΡΠ΅Π°Π»ΡΠ½ΡΠ΅ ΠΏΠΎΡΠ΅ΡΠΈΡΠ΅Π»ΠΈ;
ΠΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΉ, ΠΆΠΈΠ²ΠΎΠΉ ΠΈ Π·Π°ΠΈΠ½ΡΠ΅ΡΠ΅ΡΠΎΠ²Π°Π½Π½ΡΠΉ ΡΡΠ°ΡΠΈΠΊ ΠΈΠ· ΡΠΈΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΏΠ΅ΠΊΡΡΠ° ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ ΠΌΠ΅Π΄ΠΈΠ°;
ΠΠΎΠ΄ΡΠΎΠ±Π½Π°Ρ ΡΡΠ°ΡΠΈΡΡΠΈΠΊΠ° ΠΏΠΎ ΠΊΠ»ΠΈΠΊΠ°ΠΌ Ρ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡΡ ΠΎΠ±ΠΆΠ°Π»ΠΎΠ²Π°Π½ΠΈΡ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ Π·Π°Π΄Π°Π½ΠΈΡ;
ΠΡΡΡΡΡΡΠ²ΠΈΠ΅ ΠΊΠΎΠΌΠΈΡΡΠΈΠΈ Π·Π° Π²Π²ΠΎΠ΄ ΡΡΠ΅Π΄ΡΡΠ² Π² ΡΠΈΡΡΠ΅ΠΌΡ
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ΠΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΌΠΎΠ½Π΅ΡΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ ΡΠ²ΠΎΠΈ Π°ΠΊΠΊΠ°ΡΠ½ΡΡ Π² ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΡ ΠΌΠ΅Π΄ΠΈΠ°, ΡΠ°ΠΊΠΈΡ ΠΊΠ°ΠΊ Twitter, Π³ΡΡΠΏΠΏΡ ΠΈ Π°ΠΊΠΊΠ°ΡΠ½ΡΡ ΠΠΊΠΎΠ½ΡΠ°ΠΊΡΠ΅, ΡΡΡΠ°Π½ΠΈΡΡ ΠΈ Π°ΠΊΠΊΠ°ΡΠ½ΡΡ Facebook, Google+ ΠΈ Π΄Π°ΠΆΠ΅ Π±Π»ΠΎΠ³ΠΈ;
ΠΠ°ΠΊΡΠΈΠΌΡΠΌ ΠΏΡΠΈΠ±ΡΠ»ΠΈ Π·Π° ΡΡΡΡ ΠΏΠΎΠ»Π½ΠΎΠΉ ΡΠ²ΠΎΠ±ΠΎΠ΄Ρ Π² Π½Π°ΠΏΠΈΡΠ°Π½ΠΈΠΈ ΡΠΎΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ΅ΠΊΡΡΠ° ΠΏΡΠΈ ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΈ ΡΡΡΠ»ΠΊΠΈ Π·Π°ΠΊΠ°Π·ΡΠΈΠΊΠ°;
ΠΠ°ΡΠ°Π½ΡΠΈΡ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΈΡ Π΄Π΅Π½Π΅Π³ Π·Π° ΡΡΡΡ ΡΠΈΡΡΠ΅ΠΌΡ Ρ ΠΎΠ»Π΄Π°;
ΠΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ Π·Π°ΡΠ°Π±ΠΎΡΠΊΠ° Π½Π΅ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²Π΅Π½Π½ΠΎ ΠΏΡΠΈ Π΄ΠΎΠ±Π°Π²Π»Π΅Π½ΠΈΠΈ ΠΏΠ»ΠΎΡΠ°Π΄ΠΊΠΈ Π² ΡΠΈΡΡΠ΅ΠΌΡ;
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I never watch Oprah. I apologize for the iemragy, but I'd rather rip out my own eyes with salad forks than watch that hideous, vapid cow.On the topic, I read Kathleen Parker's book "Save the Males" and couldn't read past chapter 7. Most depressing book I ever read in my life. Any woman that thinks life as a man in contemporary America is just a joyride should read that book. Also, "No More Mr. Nice Guy" by Dr. Robert A. Glover, which I'm reading now. Also addresses how life as a man in western society can be an exercise in getting your head completely f'ed up.Just my 2 cents. You may now amble about the cabin.
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ΠΠ½ΡΠ΅ΡΠ½Π΅Ρ-ΠΌΠ°Π³Π°Π·ΠΈΠ½ Π₯ΠΎΡΠΎΡΠΈΠ΅ ΠΏΠΎΠ΄Π°ΡΠΊΠΈ ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ΅Ρ ΠΏΡΠΎΠ΄Π°ΠΆΡ ΡΡΠ²Π΅Π½ΠΈΡΠΎΠ² ΠΠ°Π³Π°Π·ΠΈΠ½ Π‘llon.ru Π·Π°Π½ΠΈΠΌΠ°Π΅ΡΡΡ ΠΏΡΠΎΠ΄Π°ΠΆΠ΅ΠΉ ΠΏΠΎΠ΄Π°ΡΠΊΠΎΠ² ΠΈ ΡΡΠ²Π΅Π½ΠΈΡΠΎΠ² Π² Π³ΠΎΡΠΎΠ΄Π΅ ΠΠΎΡΠΊΠ²Π° ΠΈ ΠΎΠ±Π»Π°ΡΡΠΈ. ΠΠ΄Π΅ΡΡ ΠΡ ΡΠΌΠΎΠΆΠ΅ΡΠ΅ ΠΏΡΠΈΠΎΠ±ΡΠ΅ΡΡΠΈ ΡΠ°ΠΌΡΡΠ°ΠΉΡΠΊΠΈΠ΅ ΠΌΠ΅ΡΠΈ, ΠΊΠΈΠ½ΠΆΠ°Π»Ρ ΠΈ Π°ΡΠ±Π°Π»Π΅ΡΡ, ΠΏΠΎΠ΄Π°ΡΠΎΡΠ½ΡΠ΅ ΠΊΡΡΠΆΠΊΠΈ ΠΈ Π±ΡΡΡΠ»ΠΈ, ΡΠ°ΡΡΠΎΡΠΎΠ²ΡΠ΅ ΠΊΡΠΊΠ»Ρ, Π° ΡΠ°ΠΊΠΆΠ΅ Π±ΡΠΎΠ½Π·ΠΎΠ²ΡΠ΅, ΡΠ°ΡΡΠΎΡΠΎΠ²ΡΠ΅ ΡΡΠ°ΡΡΡΡΠΊΠΈ, ΡΠΊΠ°ΡΡΠ»ΠΊΠΈ Π΄Π»Ρ ΡΠΊΡΠ°ΡΠ΅Π½ΠΈΠΉ. ΠΡΠΎΠΌΠ΅ ΡΠΎΠ³ΠΎ, Π·Π°ΠΊΠ°ΠΆΠΈΡΠ΅ ΡΠΎΠ΄ΠΎΡΠ»ΠΎΠ²Π½ΡΠ΅ ΠΊΠ½ΠΈΠ³ΠΈ, ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΠ°ΡΡΡΠ½ΠΈΠΊΠΎΠ² ΠΈ Π΄ΡΡΠ³ΠΎΠ΅. ΠΠΎΡΡΡΠΏΠ½ΡΠ΅ ΡΠ΅Π½Ρ. ΠΠΎΠ·ΠΌΠΎΠΆΠ½Π° Π΄ΠΎΡΡΠ°Π²ΠΊΠ°. ΠΠΎΠ»ΡΡΠ΅ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΈ http://cllon.ru!
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11]ΠΡΠΈΠ³ΠΈΠ½Π°Π»ΡΠ½ΡΠ΅ ΠΏΠΎΠ΄Π°ΡΠΊΠΈ ΠΈ ΡΡΠ²Π΅Π½ΠΈΡΡ Ρ Π΄ΠΎΡΡΠ°Π²ΠΊΠΎΠΉ ΠΏΠΎ Π ΠΎΡΡΠΈΠΈ
ΠΠ½ΡΠ΅ΡΠ½Π΅Ρ-ΠΌΠ°Π³Π°Π·ΠΈΠ½ Β«Π₯ΠΎΡΠΎΡΠΈΠ΅ ΠΏΠΎΠ΄Π°ΡΠΊΠΈΒ» Π±ΠΎΠ»Π΅Π΅ 2000 Π½Π°ΠΈΠΌΠ΅Π½ΠΎΠ²Π°Π½ΠΈΠΉ ΠΏΠΎΠ΄Π°ΡΠΎΡΠ½ΠΎΠΉ ΠΈ ΡΡΠ²Π΅Π½ΠΈΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠΈ
Π₯ΠΎΡΠΈΡΠ΅ ΡΠ΄Π΅Π»Π°ΡΡ ΠΎΡΠΈΠ³ΠΈΠ½Π°Π»ΡΠ½ΡΠΉ ΠΏΠΎΠ΄Π°ΡΠΎΠΊ? ΠΠ°Ρ ΠΎΠ΄ΠΈΡΠ΅ Π² ΠΈΠ½ΡΠ΅ΡΠ½Π΅Ρ-ΠΌΠ°Π³Π°Π·ΠΈΠ½ Π‘llon.ru. ΠΠ΄Π΅ΡΡ ΠΡ ΡΠΌΠΎΠΆΠ΅ΡΠ΅ ΠΏΡΠΈΠΎΠ±ΡΠ΅ΡΡΠΈ ΡΠ°ΠΌΡΡΠ°ΠΉΡΠΊΠΈΠ΅ ΠΌΠ΅ΡΠΈ, ΠΏΡΠ°Π²ΠΎΡΠ»Π°Π²Π½ΡΠ΅ ΠΈ Π²ΠΎΡΡΠΎΡΠ½ΡΠ΅ ΠΏΠ°Π½Π½ΠΎ, Π±ΠΈΠ·Π½Π΅Ρ-ΡΡΠ²Π΅Π½ΠΈΡΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΊΠ°Π½Π΄Π΅Π»ΡΠ±ΡΡ ΠΈ Π²Π°Π·Ρ, Π³Π»ΠΎΠ±ΡΡΡ-Π±Π°ΡΡ ΠΈ Π΄ΡΡΠ³ΠΎΠ΅.
5 ΠΏΡΠΈΡΠΈΠ½, ΠΏΠΎ ΠΊΠΎΡΠΎΡΡΠΌ ΡΡΠΎΠΈΡ ΠΏΡΠΈΠΎΠ±ΡΠ΅ΡΡΠΈ ΠΏΠΎΠ΄Π°ΡΠΊΠΈ ΠΈ ΡΡΠ²Π΅Π½ΠΈΡΡ Ρ Π½Π°Ρ
1.ΠΠΆΠ΅Π½Π΅Π΄Π΅Π»ΡΠ½ΠΎΠ΅ ΠΎΠ±Π½ΠΎΠ²Π»Π΅Π½ΠΈΠ΅. ΠΠΎΡΡΠΎΡΠ½Π½ΠΎ ΡΠ°ΡΡΠΈΡΡΠ΅ΠΌ Π½Π°Ρ Π°ΡΡΠΎΡΡΠΈΠΌΠ΅Π½Ρ β Π²Ρ Π²ΡΠ΅Π³Π΄Π° ΡΠΌΠΎΠΆΠ΅ΡΠ΅ Π½Π°ΠΉΡΠΈ ΡΡΠΎ-Π½ΠΈΠ±ΡΠ΄Ρ Π½ΠΎΠ²Π΅Π½ΡΠΊΠΎΠ΅.
2.ΠΠΎΠΌΠΎΡΡ Π² Π²ΡΠ±ΠΎΡΠ΅. Π‘ΠΎΠΌΠ½Π΅Π²Π°Π΅ΡΠ΅ΡΡ Π² ΠΏΠΎΠΊΡΠΏΠΊΠ΅? ΠΠΎΠ·Π²ΠΎΠ½ΠΈΡΠ΅ Π½Π°ΠΌ ΠΏΠΎ Π½ΠΎΠΌΠ΅ΡΡ, ΠΈ ΠΌΡ ΠΏΠΎΠ΄Π±Π΅ΡΠ΅ΠΌ ΠΏΠΎΠ΄Ρ ΠΎΠ΄ΡΡΠΈΠΉ Π²Π°ΡΠΈΠ°Π½Ρ.
3.ΠΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠ΅ ΡΠΎΠ²Π°ΡΡ. Π£ Π½Π°Ρ Π½Π΅Ρ Π΄Π΅ΡΠ΅Π²ΡΡ ΠΊΠΈΡΠ°ΠΉΡΠΊΠΈΡ ΠΏΠΎΠ΄Π΄Π΅Π»ΠΎΠΊ: Π²ΡΠ΅ ΡΠΎΠ²Π°ΡΡ ΠΏΡΠΈΠ²Π΅Π·Π΅Π½Ρ ΠΈΠ· ΠΠ½Π΄ΠΈΠΈ, ΠΡΠ΅ΡΠ½Π°ΠΌΠ°, Π’Π°ΠΈΠ»Π°Π½Π΄Π°.
4.ΠΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ Π³Π°ΡΠ°Π½ΡΠΈΠΈ. ΠΠ΅ ΠΏΠΎΠ½ΡΠ°Π²ΠΈΠ»ΡΡ ΡΠΎΠ²Π°Ρ? ΠΠ±ΠΌΠ΅Π½ΡΠ΅ΠΌ Π½Π° Π΄ΡΡΠ³ΠΎΠΉ ΠΈΠ»ΠΈ Π±Π΅Π· Π»ΠΈΡΠ½ΠΈΡ Π²ΠΎΠΏΡΠΎΡΠΎΠ² Π²Π΅ΡΠ½Π΅ΠΌ Π΄Π΅Π½ΡΠ³ΠΈ.
5.ΠΡΡΡΡΠ°Ρ Π΄ΠΎΡΡΠ°Π²ΠΊΠ°. ΠΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΠ΅ Π² ΠΊΠ°ΡΠ°Π»ΠΎΠ³Π΅ Π½Π°ΠΈΠΌΠ΅Π½ΠΎΠ²Π°Π½ΠΈΠ΅ Π΅ΡΡΡ Π½Π° Π½Π°ΡΠ΅ΠΌ ΡΠΊΠ»Π°Π΄Π΅ β ΠΏΡΠΈΠ²Π΅Π·Π΅ΠΌ Π·Π°ΠΊΠ°Π· Π² ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ Π΄Π½Ρ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ»Π°ΡΡ.
ΠΡΠΎΡ ΡΠΎΠΏΠΈΠΊ ΡΠ°ΠΊΠΆΠ΅ ΠΈΡΡΡ ΠΏΠΎ Π·Π°ΠΏΡΠΎΡΠ°ΠΌ:
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ΠΏΠΎΠ΄Π°ΡΠΎΠΊ ΠΌΡΠΆΡ Π½Π° Π΄Π΅Π½Ρ ΡΠΎΠΆΠ΄Π΅Π½ΠΈΡ
ΠΠΎΠ΄Π°ΡΠΎΠΊ Π»ΡΠ±ΠΈΠΌΠΎΠΌΡ Π½Π° Π΄Π΅Π½Ρ ΡΠΎΠΆΠ΄Π΅Π½ΠΈΡ
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ΠΠΎΠ³Π΄Π° ΠΎΠ±ΡΡΠ½ΡΠΉ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊ ΡΡΠ°Π»ΠΊΠΈΠ²Π°Π΅ΡΡΡ Ρ ΡΠ΅ΠΌ ΡΡΠΎ ΠΏΠΎΡΠ΅ΡΡΠ» ΠΊΠ»ΡΡΠΈ ΠΈΠ»ΠΈ Π·Π°ΠΌΠΎΠΊ Π±ΡΠ» ΡΠ»ΡΡΠ°ΠΉΠ½ΠΎ ΠΈΠ»ΠΈ ΡΠΌΡΡΠ»Π΅Π½Π½ΠΎ Π²ΡΠ²Π΅Π΄Π΅Π½ ΠΈΠ· ΡΡΡΠΎΡ ΠΌΡ Π³ΠΎΡΠΎΠ²Ρ ΠΏΡΠΈΠΉΡΠΈ Π½Π° ΠΏΠΎΠΌΠΎΡΡ ΠΈ Π²ΡΠΊΡΡΡΡ Π²Π°Ρ Π·Π°ΠΌΠΎΠΊ. ΠΡΠΊΡΡΡΠΈΠ΅ Π·Π°ΠΌΠΊΠΎΠ² ΠΌΠΎΠΆΠ΅Ρ ΠΏΡΠΎΠΈΡΡ ΠΎΠ΄ΠΈΡΡ ΠΊΠ°ΠΊ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ»Π΅ΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°, ΡΠ°ΠΊ ΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΡ ΠΎΡΠΌΡΡΠ΅ΠΊ – ΡΡΠΎ Π·Π°Π²ΠΈΡΠΈΡ ΠΎΡ ΡΠΈΠΏΠ° Π·Π°ΠΌΠΊΠ°, Π΅Π³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΈ ΠΊΠ°ΠΆΠ΄ΡΠΉ Π½Π°Ρ ΠΌΠ°ΡΡΠ΅Ρ Π·Π½Π°Π΅Ρ ΠΊΠ°ΠΊ ΡΠ°Π±ΠΎΡΠ°ΡΡ Ρ ΡΠ΅ΠΌ ΠΈΠ»ΠΈ ΠΈΠ½ΡΠΌ Π²ΠΈΠ΄ΠΎΠΌ Π·Π°ΠΌΠΊΠ°. ΠΡΠ΅ ΡΡΠΎ Π²Π°ΠΌ Π½ΡΠΆΠ½ΠΎ ΡΠ΄Π΅Π»Π°ΡΡ – ΡΡΠΎ ΠΎΡΠΎΡΠΌΠΈΡΡ Π²ΡΠ·ΠΎΠ² ΠΈ ΠΏΠΎΠ΄ΠΎΠΆΠ΄Π°ΡΡ Π½Π΅ΠΊΠΎΡΠΎΡΠΎΠ΅ Π²ΡΠ΅ΠΌΡ ΠΏΡΠΈΠ±ΡΡΠΈΡ ΠΌΠ°ΡΡΠ΅ΡΠ° ΠΏΠΎ Π·Π°ΠΌΠΊΠ°ΠΌ. ΠΠ°ΡΡΠ΅Ρ ΠΏΠΎΠ΅Π΄Π΅Ρ ΠΊ Π²Π°ΠΌ ΠΎΠ±ΡΠ·Π°ΡΠ΅Π»ΡΠ½ΠΎ, Π² ΠΊΠ°ΠΆΠ΄ΠΎΠΌ ΡΠ°ΠΉΠΎΠ½Π΅ ΠΠΎΡΠΊΠ²Ρ ΡΠ°Π±ΠΎΡΠ°Π΅Ρ ΠΏΠΎ Π½Π΅ΡΠΊΠΎΠ»ΡΠΊΠΎ ΠΌΠ°ΡΡΠ΅ΡΠΎΠ² ΠΏΠΎ Π²ΡΠΊΡΡΡΠΈΡ Π·Π°ΠΌΠΊΠΎΠ² ΠΎΡ Π½Π°ΡΠ΅ΠΉ ΠΊΠΎΠΌΠΏΠ°Π½ΠΈΠΈ. ΠΠΎΡΠ»Π΅ Π²ΡΠΊΡΡΡΠΈΡ Π·Π°ΠΌΠΊΠ° ΠΌΡ ΠΏΠΎΠΌΠΎΠΆΠ΅ΠΌ Π²Π°ΠΌ Π² Π·Π°ΠΊΡΠΏΠΊΠ΅ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΡΡΡΠΈΡ ΠΈ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠ΅ Π½ΠΎΠ²ΠΎΠ³ΠΎ Π±ΠΎΠ»Π΅Π΅ Π½Π°Π΄Π΅ΠΆΠ½ΠΎΠ³ΠΎ Π·Π°ΠΌΠΊΠ° Π΄Π»Ρ Π²Π°ΡΠ΅ΠΉ Π΄Π²Π΅ΡΠΈ.
ΡΠ»ΡΠΆΠ±Π° ΠΏΠΎ ΡΠ΅ΠΌΠΎΠ½ΡΡ Π·Π°ΠΌΠΊΠ° Π² Π΄Π²Π΅ΡΠΈ
seo ΠΏΡΠΎΠ΄Π²ΠΈΠΆΠ΅Π½ΠΈΠ΅ ΡΠ°ΠΉΡΠ° 2019
FDA issues new warning for Plavix β The Chart – CNN.com Blogs
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adjoxysceqf
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Your money has arrived!!!
Bitcoin turns lunch money into thousands >> http://freeforryou.blogspot.ie
ΠΡΠΈΠ½ΡΠ»ΠΈ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠ΅ΡΠ²Π°ΡΡ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΡ? ΠΡΠ»ΠΈ ΡΠ²Π΅ΡΠ΅Π½Ρ Π² Π½Π΅ΠΌ, Π·Π½Π°ΡΠΈΡ ΠΈΡΠΈΡΠ΅ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΡΠΉ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠΉ Π²Π°ΡΠΈΠ°Π½Ρ β ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ Ρ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π΅Π½ΠΈΠ΅ΠΌ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³Π°. ΠΠ° ΡΠ°ΠΉΡΠ΅ https://medabort.kiev.ua/ Π΅ΡΡΡ ΠΎΠ½Π»Π°ΠΉΠ½ ΡΠ΅ΡΡ Π½Π° Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΡ, ΠΎΠ½ ΠΏΠΎΡΠ»ΡΠΆΠΈΡ ΠΏΠΎΠ΄ΡΠΊΠ°Π·ΠΊΠΎΠΉ Π΅ΡΠ»ΠΈ Π²Ρ Π½Π΅ Π΄Π΅Π»Π°Π»ΠΈ ΡΠ΅ΡΡ. ΠΠΎ Π½Π°Ρ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ ΡΠΎΡΠ½ΠΎ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡ, Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½Ρ Π»ΠΈ ΠΡ, Π½ΠΈΠΊΡΠΎ Π½Π΅ ΡΠ·Π½Π°Π΅Ρ, ΠΊΡΠΎΠΌΠ΅ ΠΠ°Ρ. ΠΠ°ΡΠ° ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ° ΠΈΠΌΠ΅Π΅Ρ Π°ΠΊΡΠ΅Π΄ΠΈΡΠ°ΡΠΈΡ ΠΈ Π»ΠΈΡΠ΅Π½Π·ΠΈΡ ΠΈ ΠΎΠ±ΠΎΡΡΠ΄ΠΎΠ²Π°Π½Π½ΡΡ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ. ΠΠ΅ Π΄ΠΎΠ²Π΅ΡΡΠΉΡΠ΅ Π·Π΄ΠΎΡΠΎΠ²ΡΠ΅, Π΅ΡΠ»ΠΈ ΡΡΠΎΠ³ΠΎ Π½Π΅Ρ. Π’Π΅ΠΌ Π±ΠΎΠ»Π΅Π΅ Π½Π° ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ ΡΠ΅Π½Π° Ρ Π½Π°Ρ Π±Π΅Π· ΡΠΊΡΡΡΡΡ Π΄ΠΎΠΏΠ»Π°Ρ, Π½Π΅ Π·Π°Π²ΡΡΠ΅Π½Π½ΡΠ΅. MedAbortHelp Π³Π°ΡΠ°Π½ΡΠΈΡΡΠ΅Ρ ΠΏΡΠΎΠ·ΡΠ°ΡΠ½ΠΎΠΉ ΠΈ Π΅Π΄ΠΈΠ½ΠΎΠΉ ΡΠ΅Π½Ρ Π½Π° ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΠΎΠ΅ ΠΏΡΠ΅ΡΡΠ²Π°Π½ΠΈΠ΅ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ Π² ΠΠΈΠ΅Π²Π΅. ΠΡ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΠΌ ΡΠ°Π±Π»Π΅ΡΠΊΠΈ Π΄Π»Ρ ΠΏΡΠ΅ΡΡΠ²Π°Π½ΠΈΡ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ, ΠΎΠ΄ΠΎΠ±ΡΠ΅Π½Π½ΡΠ΅ ΠΠΈΠ½Π·Π΄ΡΠ°Π²ΠΎΠΌ. Π ΠΏΠ°ΠΊΠ΅Ρ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ Π²Ρ ΠΎΠ΄ΡΡ ΡΠ°Π±Π»Π΅ΡΠΊΠΈ, Π°Π½Π°Π»ΠΈΠ·Ρ ΠΈ ΠΌΠ°Π·ΠΊΠΈ, ΠΎΡΠΌΠΎΡΡ Π²ΡΠ°ΡΠ° ΠΈ ΠΏΠΎΠ»Π½ΠΎΡΠ΅Π½Π½ΡΠΉ ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ. ΠΠΎΠΌΠ½ΠΈΡΠ΅, ΡΡΠΎ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ Π΄ΠΎΠΏΡΡΡΠΈΠΌΠΎ ΠΏΡΠΈΠΌΠ΅Π½ΡΡΡ ΠΏΡΠΈ ΡΡΠΎΠΊΠ΅ Π΄ΠΎ 7 Π½Π΅Π΄Π΅Π»Ρ. Π Π²Π°ΠΊΡΡΠΌΠ½ΡΠΉ Π°Π±ΠΎΡΡ, ΡΠ΅Π½Π° Π½Π° ΠΊΠΎΡΠΎΡΡΠΉ Π²ΡΡΠ΅, ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΡΡΡ ΠΏΡΠΈ ΡΡΠΎΠΊΠ΅ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ ΠΏΠΎ Π£ΠΠ Π΄ΠΎ 12 Π½Π΅Π΄Π΅Π»Ρ. ΠΡΠΎΡ ΡΠΏΠΎΡΠΎΠ± ΡΠ°ΠΊΠΆΠ΅ Π±ΠΎΠ»Π΅Π΅ Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½ΡΠΉ, ΡΠ΅ΠΌ Ρ ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π±ΠΎΡΡ. ΠΡΠ»ΠΈ ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΡΠΎΠΊ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ, Π·Π²ΠΎΠ½ΠΈΡΠ΅ ΡΠ΅ΠΉΡΠ°Ρ. ΠΠΎΠΌΠΎΠΆΠ΅ΠΌ ΠΠ°ΠΌ ΠΈ ΡΠ°ΡΡΠΊΠ°ΠΆΠ΅ΠΌ ΠΏΠΎΠ΄ΡΠΎΠ±Π½Π΅Π΅. ΠΠ²ΠΎΠ½ΠΈΡΠ΅!: (063) 978-89-44, (099) 298-75-05, (044) 360-83-83, (067) 756-88-66
ΠΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ ΠΠΈΠ΅Π² – Medabort.Kiev.Ua: ΠΌΠ΅Π΄ΠΈΠΊΠ°ΠΌΠ΅Π½ΡΠΎΠ·Π½ΡΠΉ Π°Π±ΠΎΡΡ ΡΡΠΎΠΊΠΈ
Π‘β‘Π Β»Π Β΅Π Π
Π Β±Π Β°Π Β·Π‘ΡΠ ΡΠ Β°
ΠΠΎΡΠΌΠ΅ΡΠΈΡΠ΅ΡΠΊΠ°Ρ, Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΠ΅Π»ΡΠ½Π°Ρ, ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ΅ Π½Π°Π½Π΅ΡΠ΅Π½ΠΈΠ΅
Π·Π°ΡΠΈΡΠ½ΡΡ ΡΡΠ΅Π΄ΡΡΠ² Π½Π° ΠΊΡΠ·ΠΎΠ² (ΠΆΠΈΠ΄ΠΊΠΎΠ΅ ΡΡΠ΅ΠΊΠ»ΠΎ, Π½Π°Π½ΠΎΠΊΠ΅ΡΠ°ΠΌΠΈΠΊΠ°,
ΡΠΈΠ»Π°Π½ΡΠΎΡΠΎΠ΄Π΅ΡΠΆΠ°ΡΠΈΠ΅ ΡΠΎΡΡΠ°Π²Ρ), ΠΏΠΎΠ»ΠΈΡΠΎΠ²ΠΊΠ° ΡΠ°Ρ.
ΠΏΠΎΡΠ½ΠΎ
ΠΠΎΠ²ΡΠΉ Π³ΠΎΠ΄ ΡΠΆΠ΅ Π±Π»ΠΈΠ·ΠΊΠΎ.
Π ΠΈΠ½ΡΠ΅ΡΠ½Π΅Ρ ΠΌΠ°Π³Π°Π·ΠΈΠ½Π΅ Π’ΠΎΠ²Π°ΡΠΎΠΌΠ°Π½ΠΈΡ.Π Π€ ΡΠ½ΠΈΠΆΠ΅Π½Ρ ΡΠ΅Π½Ρ.
ΠΠ΅ΡΠΏΠ»Π°ΡΠ½Π°Ρ Π΄ΠΎΡΡΠ°Π²ΠΊΠ°.
Π‘Π°ΠΌΡΠΉ Π²ΡΠ³ΠΎΠ΄Π½ΡΠ΅ ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½ΠΈΡ Π½Π° ΠΠ²ΡΠΎΡΡΠ΅ΠΊΠΈ ΡΠΎΠ»ΡΠΊΠΎ ΡΠ΅ΠΉΡΠ°Ρ.
The tracer can we own foremost from the hemicranias of antibiotics who. cialis canada Wxzmad hnkvfc
ΠΡΠ»ΠΎΠΆΠ΅Π½Π½ΡΠΉ ΠΏΠΎΡΡΠΈΠ½Π³ Π² ΠΈΠ½ΡΡΠ°Π³ΡΠ°ΠΌ ΠΈ Π² ΠΎΡΡΠ°Π»ΡΠ½ΡΠ΅ ΡΠΎΡ ΡΠ΅ΡΠΈ Pinterest ΠΡΠΎΠΊΡΠΈ ΠΈ Π΄ΡΡΠ³ΠΈΠ΅ ΠΌΠΎΡΠ½ΡΠ΅ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΡ
FDA issues new warning for Plavix β The Chart – CNN.com Blogs
[url=http://www.g9dd2i668j8j1xonop774c14jl195f0ts.org/]ugeiqdzvpl[/url]
geiqdzvpl http://www.g9dd2i668j8j1xonop774c14jl195f0ts.org/
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Π²ΠΏΠΎΠ»Π½Π΅ ΡΠ΅Π±Π΅ Π³ΠΎΠ΄Π½ΠΎΡΠ°
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ΡΠ³ΡΠΎΠ²Ρ Π°Π²ΡΠΎΠΌΠ°ΡΠΈ 777 Π³ΡΠ°ΡΠΈ ΠΎΠ½Π»Π°ΠΉΠ½