September 17th, 2009
09:39 AM ET

Are there new treatments available for lupus?

As a regular feature of CNNhealth.com, our team of expert doctors answers readers’ questions. Here’s a question for Dr. Gupta.

From Carolyn in Goliad, Texas:

What is the latest treatment or drug that is showing success in treating lupus?


Thanks for your question Carolyn.  Lupus  is a chronic autoimmune disease which seems to affect mainly women.  Essentially your body’s immune system begins to attack not only foreign invaders, like viruses, but your own tissues and organs.  There are four types of the disease but the most common is called systemic lupus erythematosus.  Doctors don’t know the cause, but they believe it’s a combination of family history and environmental triggers.  Those triggers can be something like an infection or even sunlight.  

Lupus can cause inflammation in just about any organ or tissue in the body, from your skin and your lungs to your kidneys.  Your doctor will determine your best treatment depending on what type of lupus you have, your signs and symptoms and their severity.  This is a disease of flare-ups and periods of remissions so your medication may also change depending on what stage you’re experiencing.  Plus, it can take months to nail down the most effective combination of treatments to best control your symptoms.  The three most common medications are nonsteroidal anti-inflammatories, corticosteroids and antimalarial drugs. 

There are currently more than 200 lupus clinical trials testing hormones, immune suppressives, stem cell transplants and biologics.  But Carolyn, after getting your email we put a call into the Lupus Foundation to find out what they considered to be the most promising.  They said lupus is difficult because patients with the same symptoms on the same medication can have different outcomes, so they consider targeted therapies the best hope – specifically biologics.  Biologics are compounds that block or interfere with your body’s immune system response.  They gave us a heads up about a large clinical trial ending in November on one such drug that they hope will help patients looking for new treatments.  Granted even if this drug is shown to be beneficial it will still have to go through the FDA review process so it will be some time before it’s available in your doctor’s office.

« Previous entry
soundoff (574 Responses)
  1. Daryl

    Is Lupus related to rheumatoid arthritis?

    September 20, 2009 at 12:00 | Report abuse | Reply
  2. Oona

    I was diagnosed with Lupus when I was 20 years old.
    I've been on a host of medications: Imuran, Dapsone, Plaquenil and last but not least, Cytoxan (IV) since my kidneys were compromised.
    Lupus has also manifested itself in the form of vasculitis (mainly in my legs; it's been 3 years since that happened and I'm still taking Lasix daily since I continue to retain fluid).

    My body cannot tolerate corticosteroids.

    I'm 28 years old and continue to take a combo of Plaquenil and Imuran daily. I've had short periods of "remission" but the illness always comes back in different forms, with different symptoms.

    I do hope a new drug is found soon. Lupus severely affects your quality of life. I also wish more people knew about the illness as it affects so many.

    September 23, 2009 at 11:29 | Report abuse | Reply
  3. S.Brittain

    YES,LUPUS IS AN AUTO IMMUNE DISEASE LIKE RHEUMATOID ARTHRITIS, AND BOTH USUALLY HAVE OTHER AUTO IMMUNE DISEASES AT THE SAME TIME..IE SJOGRENS, REYNAUDS and others. It is important to get treatment from a rheumatologist because alot can be done now to prevent the diseases' progression.

    September 23, 2009 at 12:29 | Report abuse | Reply
  4. lisa

    I was diagnosed with Lupus when I was pregnant with my daughter 25 years ago. I tried several antiinflammatories, none of which really were effective. I was in the hospital 3 times with flare ups. I was put on prednisone while in the hospital.(high doses).
    I've been on it since..over 20 years and would LOVE to be able to get off of it and on something less harmful. I'm hoping that a new medicine/treatment will be found soon so I am able.

    October 16, 2009 at 13:58 | Report abuse | Reply
  5. Barbara Pierce

    I was diagnosed with lupus 9 years ago. I also have bad kidneys which they tell me is from the use of Mobic and Celebrex. While I have a wonderful kidney doctor I'm having trouble finding a rheumatologist that doesn't dispute the diagnosis because they didn't make it. I have 5 of the indications and joint pain and mouth sores are the worst. Any suggestions would be appreciated.

    April 12, 2010 at 13:12 | Report abuse | Reply
  6. lupus treatment

    An interesting discussion is definitely worth comment. I believe that you ought to publish more about this subject matter, it might not be a taboo matter but generally people do not speak about these issues. To the next! Many thanks!!

    March 8, 2012 at 08:40 | Report abuse | Reply
  7. Whitney O'leary

    All discussions and journal articles are helpful. Endocrinology is becoming a rarity:( As a Type 1 Diabetic for 39 years, Lupus, Pituitary Adenoma; I'm the anomaly according to medical science. I continue to research any information that allows me to be the active member of society I expect myself to maintain. Keep researching:) Thank You!

    January 20, 2015 at 23:45 | Report abuse | Reply
  8. FnrdEncox

    u. s. overnight viagra online viagra viagra uk

    November 24, 2020 at 08:20 | Report abuse | Reply
  9. DbsfZisse

    buy viagra toronto canadian viagra prescription 805551 sildenafil

    November 25, 2020 at 05:32 | Report abuse | Reply
  10. FdbvZisse

    cheap viagra pills uk cheap viagra online free shipping cost of generic viagra in canada

    November 26, 2020 at 18:47 | Report abuse | Reply
  11. KbrgMile

    online viagra united states how much is generic viagra in canada sildenafil 20 mg online canada

    November 26, 2020 at 18:58 | Report abuse | Reply
  12. FmsgEncox

    wirkung viagra nach samenerguss viagra erfindungsjahr can u take xanax with viagra

    November 27, 2020 at 01:27 | Report abuse | Reply
  13. JgscCrulk

    can i pay someone to do my homework for me homework help mummies essay writing mla format

    November 28, 2020 at 07:41 | Report abuse | Reply
  14. DvscZisse

    career research paper method of writing an essay 7th grade essay writing worksheets

    November 30, 2020 at 08:57 | Report abuse | Reply
  15. FtghEncox

    essays about college education list of transitional words for writing essays methodology essay

    November 30, 2020 at 09:30 | Report abuse | Reply
  16. FnrhEncox

    viagra brand frizer viagra pill viagra online netherlands

    November 30, 2020 at 15:38 | Report abuse | Reply
  17. FqfEncox

    can you do my homework please master essay writing algebra homework app

    December 1, 2020 at 02:43 | Report abuse | Reply
  18. FnsbEncox

    psychology dissertations help me write my assignment library based dissertation

    December 1, 2020 at 15:09 | Report abuse | Reply
  19. FgsZisse

    research paper 2nd amendment research paper using apa style fake essay writer

    December 1, 2020 at 22:35 | Report abuse | Reply
  20. KwgdMile

    theses and dissertations online writing essay top college application essays

    December 2, 2020 at 02:07 | Report abuse | Reply
  21. FsfEncox

    we do your math homework essay nurse help writing a research paper thesis

    December 2, 2020 at 14:43 | Report abuse | Reply
  22. JgsvCrulk

    buy generic viagra with paypal viagrarx discount viagra usa

    December 9, 2020 at 17:11 | Report abuse | Reply
  23. FbsbEncox

    canadianmed cialis levitra vs cialis side effects generic cialis online purchase

    December 11, 2020 at 05:54 | Report abuse | Reply
  24. FgnsZisse

    costa rica cialis sale orginal cialis buy cialis via pay pal

    December 11, 2020 at 15:51 | Report abuse | Reply
  25. FgrsEncox

    viagra mit paypal viagra no prescriptin compare generic viagra prices

    December 11, 2020 at 16:01 | Report abuse | Reply
  26. FqbfEncox

    cialis liquid for sale cialis for sale online buy cialis withiut a prescription

    December 11, 2020 at 16:50 | Report abuse | Reply
  27. FsfgEncox

    viagra light buy viagra australia buy viagra online\'

    December 13, 2020 at 13:10 | Report abuse | Reply
  28. KhedMile

    365 pills viagra viagra australia viagra doctor samples

    December 13, 2020 at 18:55 | Report abuse | Reply
  29. DvnjZisse

    buy generic viagra with dapoxetine uk top online generic viagra easy avilibility of viagra

    December 15, 2020 at 03:48 | Report abuse | Reply
  30. FhsnZisse

    viagra for sale without prescription and next day delivery viagra usa buy viagra online australia

    December 16, 2020 at 14:48 | Report abuse | Reply
  31. LokuEncox

    canadian pharmacies online 24 hr pharmacy near me ed pills that work quickly

    January 8, 2021 at 19:57 | Report abuse | Reply
  32. FwsxEncox

    e d online drugstore online pharmacy no prescription

    January 9, 2021 at 06:27 | Report abuse | Reply
  33. JlloCrulk

    erectile dysfunction drug texas state board of pharmacy drugstore makeup

    January 9, 2021 at 10:09 | Report abuse | Reply
  34. JtmfEncox

    discount pharmacy uk pharmacy pharmacy rx

    January 10, 2021 at 06:30 | Report abuse | Reply
  35. AqwsEncox

    ed treatment drug rx erectile dysfunction drug

    January 11, 2021 at 02:01 | Report abuse | Reply
  36. Isabella Bobby

    I am cured from herpes with his herbal Med! I feel so much happy for being so empathetic and helpful to me, ! His website is (( https://robinbuckler. com )) or (( robinsonbuckler11 @gmail. com )) ...He restored my relationship with his love spell






    January 11, 2021 at 15:25 | Report abuse | Reply
  37. KhthMile

    dollar store drug test best drugstore bb cream 24 hour drug store near me

    January 11, 2021 at 19:49 | Report abuse | Reply
  38. FgvdZisse

    global pharmacy canada board of pharmacy best drugstore primer

    January 12, 2021 at 17:25 | Report abuse | Reply
  39. JvcxCrulk

    buy viagra cialis mix online how to use viagra for men viagra in peru how can i buy viagra online australia blood pressure medicne and viagra viagra,cialis india adderall and viagra buy viagra online usa sale viagra viagra for sale in the uk viagra online nz where to buy viagra in toronto quickly viagra professional vs viagra is it illegal to buy viagra online viagra sale uk

    January 14, 2021 at 04:58 | Report abuse | Reply
  40. FgnhZisse

    viagra professional generic were can you buy kamagra and viagra in ireland brand name viagra canada brand name viagra canada viagra no prescription overnight delivery dp viagra we can i buy viagra without a prescription viagra buy in melbourne viagra preço viagra for sale viagra\\\' buy super viagra viagra canada head office viagra purchase online usa viagra super active plus

    January 16, 2021 at 19:51 | Report abuse | Reply
  41. KlioMile

    viagra 100 viagra throught paypall viagra on line\' viagra purchase viagra in hamburg viagra pay viagra gold for sale viagra best price buy viagra what is better viagra or levitra hard for 36hr like viagra buy viagra online priligy viagra australia viagra 150 mg viagra professional 100mg

    January 16, 2021 at 20:31 | Report abuse | Reply
  42. NlbxZisse

    buy generic viagra what is better viagra or cialis or levitra?? paypal buy viagra viagra for sale in uk reliable cheap viagra buy viagra without prescrip buy viagra and prescription drugs viagra cheap master card buy prescription only viagra youtube viagra prices viagra mit paypal zahlen viagra repacement viagra mon line viagra buy online australia viagra cheap cheapest

    January 17, 2021 at 19:32 | Report abuse | Reply
  43. Chi Rockett


    January 17, 2021 at 22:43 | Report abuse | Reply
  44. LcxEncox

    viagra pills for sale viagra on line nz viagra headquarters http://genqpviag.com/ – online viagra canada pharmacy ’

    January 18, 2021 at 15:28 | Report abuse | Reply
  45. JvcbxCrulk

    cialis in usa buy cialis where to find cheap cialis http://phrcialiled.com/ – cialis tablets for sell ’

    January 19, 2021 at 05:19 | Report abuse | Reply
  46. AqbvEncox

    viagra for cheap viagra/cialis black and gold 800 best viagra http://acialaarx.com/ – what if viagra doesnt work another tablet ’

    January 20, 2021 at 20:39 | Report abuse | Reply
  47. KbctMile

    cialis purchase canada cialis in canada cheap cialis australia http://mycialedst.com/ – acquista cialis paypal ’

    January 21, 2021 at 18:01 | Report abuse | Reply
  48. FbdhZisse

    but cialis overnight delivery cialisВ® cheep cialis http://21cialismen.com/ – cialis lilly 20mg ’

    January 21, 2021 at 20:16 | Report abuse | Reply
  49. NlbxZisse

    cialis coupon code cialis no prescription canada review buy cialis online http://cialijomen.com/ – cialis online/canada ’

    January 22, 2021 at 19:29 | Report abuse | Reply
  50. FmfvEncox

    cialis mastercard buy cialis online i need cialis overnight http://sjcialis.com/ – buy generic cialis ’

    January 23, 2021 at 20:34 | Report abuse | Reply
1 2 3 4 5 6 7 8 9 10 11 12

Leave a Reply to RfvbZisse


CNN welcomes a lively and courteous discussion as long as you follow the Rules of Conduct set forth in our Terms of Service. Comments are not pre-screened before they post. You agree that anything you post may be used, along with your name and profile picture, in accordance with our Privacy Policy and the license you have granted pursuant to our Terms of Service.

« Previous entry
About this blog

Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.