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The road to a more dangerous malaria?
A new study warns a malaria vaccine could lead to a more dangerous parasite.
August 1st, 2012
09:57 AM ET

The road to a more dangerous malaria?

Doctors have dreamed for decades of a vaccine against malaria, which sickens more than 200 million people every year. But a new study warns of a potential pitfall: a malaria vaccine could lead to an even more dangerous parasite.

The paper was published this week in the journal PLOS.  Researchers working with the leading candidate vaccine immediately questioned it, saying they’ve seen no sign of dangerous changes as a result of their work.

The study was performed on mice. Researchers monitored the malaria parasite through several generations, comparing parasites in mice who had been inoculated against malaria with mice those who did not receive vaccinations. In the former group, new malaria infections caused more severe illness, as measured by red blood cell count.

Vicki Barclay, the study’s lead author, said it shows a need to track the long-term impact of any malaria vaccine, especially since any such vaccine is expected to be “leaky” - meaning it won’t offer complete protection, and the disease will continue to spread, albeit at a slower rate. The fear is that malaria could become more deadly, even as it continues to infect people. FULL POST


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Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.

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