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More on Robin Roberts' rare blood syndrome
June 11th, 2012
11:04 AM ET

More on Robin Roberts' rare blood syndrome

"Good Morning America's" Robin Roberts announced this morning that she has myelodysplastic syndrome, or MDS. The rare syndrome is also known as preleukemia.

MDS can be broken down by its name: Myeloid refers to a type of blood cell; dysplasia means a problem with the development of those cells.

The condition occurs when "something goes wrong in your bone marrow ā€” the spongy material inside your bones where blood cells are made," according to the Mayo Clinic.

A healthy person's bone marrow produces stem cells that mature into blood cells. But the bone marrow of a person with MDS produces abnormal stem cells that turn into defective blood cells.

Deformed cells get into the bloodstream and eventually outnumber healthy blood cells, according to the National Cancer Institute. Often the deformed blood cells don't live as long as they should, producing a shortage in the body.

There are several types of MDS, depending on the kind of myeloid cells - red blood cells, white blood cells or platelets - that are being affected. Having too few red blood cells results in anemia; having too few white blood cells can result in frequent infections.

The term "preleukemia" is a bit misleading, as most MDS cases do not become cancerous. Certain types of MDS can progress to acute myeloid leukemia, however.

MDS can be caused by exposure to chemotherapy and radiation, common cancer treatments. (Roberts is a breast cancer survivor.) Other risk factors include being over 60 years old and/or being exposed to other chemicals such as benzene, according to the Aplastic Anemia & MDS International Foundation.

Symptoms are rare during the early stage of the disease, but can include tiredness, shortness of breath and easy bruising/bleeding. Doctors generally diagnose through a blood test and a bone marrow biopsy.

Unfortunately there is no known cure for MDS. The goal for treatment is to keep healthy blood cells circulating as long as possible.

Blood transfusions can help slow the disease by replacing bad cells with good cells. Medications can also be used to increase the production of healthy cells.

Another option is a bone marrow stem cell transplant, in which doctors administer chemotherapy drugs to destroy defective blood cells, and insert healthy cells from a donor to replace them. But there are high risks involved in this procedure, according to the Mayo Clinic, even among people who are young and relatively healthy.

Roberts wrote in a statement that she will undergo chemotherapy ahead of a bone marrow transplant later this year. Her sister, who is a match, is donating the bone marrow.


soundoff (61 Responses)
  1. mount and blade pvp

    .....dude....i'm just speechless. Who the hell told you that? rubbish? The white ball in the sky is GOD???....smh get a dame telescope and look for yourself. I know god is not some "rock" in the sky. You must leave under a rock.

    [youtube=http://www.youtube.com/watch?v=S-3STqujUS8&w=640&h=390]

    September 17, 2013 at 15:20 | Report abuse | Reply
  2. rome 2 cool battle

    Interesting. But does a small part of the moon count as 'the moon' if I take a glass of water from the Pacific Ocean and bring it home, is it still 'the Pacific Ocean'? I would agree that it WAS PART OF the Pacific Ocean, but can an isolated segment be regarded as representative of the whole, to which? it is no longer attached, especially when separated by so large a distance?

    [youtube=http://www.youtube.com/watch?v=1hoRt2TutPg&w=640&h=390]

    September 24, 2013 at 21:45 | Report abuse | Reply
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Get a behind-the-scenes look at the latest stories from CNN Chief Medical Correspondent, Dr. Sanjay Gupta, Senior Medical Correspondent Elizabeth Cohen and the CNN Medical Unit producers. They'll share news and views on health and medical trends - info that will help you take better care of yourself and the people you love.